| 1. |
- Ask, Per, et al.
(författare)
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Combined pH and pressure measurement device for oesophageal investigations.
- 1981
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Ingår i: Medical and Biological Engineering and Computing. - 0140-0118 .- 1741-0444. ; 19:4, s. 443-446
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Tidskriftsartikel (refereegranskat)abstract
- A combined pH- and pressure-measurement device for oesophageal investigations has been designed using monocrystalline antimony pH electrodes and perfused polyvinyl catheters. The combined device facilitates pressure measurements simultaneously with pH recording, both distal and proximal to the pH electrode. The device is easier to pass through the nose to the oesophagus than the conventional glass pH electrode. pH and pressure measurements in the oesophagus are therefore simplified and valuable information about the function of the region of the lower oesophageal sphincter is added owing to the simultaneous recording of the two parameters.
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| 2. |
- Biberfeld, G, et al.
(författare)
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Enzyme immunoassays for the demonstration of antibodies to HIV-2SBL-6669 and HTLV-IV (SIVmac).
- 1988
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Ingår i: AIDS. - 0269-9370 .- 1473-5571. ; 2:3, s. 195-9
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Tidskriftsartikel (refereegranskat)abstract
- Enzyme-linked immunosorbent assays (ELISA) were developed for the demonstration of antibodies to HIV-2 using disrupted virions of the SBL-6669 isolate of HIV-2 and the so-called human T-lymphotropic virus type IV (HTLV-IV), recently found to be identical with the simian immunodeficiency virus (SIVmac), as antigens. Three hundred sera from West African subjects, attending an outward clinic in Bissau for examination of suspected tuberculosis, were tested by these two assays as well as by a commercially available anti-HIV-2 ELISA (ELAVIA II). Fifty of these sera were positive in all three ELISAs as well as in Western blot tests against HTLV-IV. Thirty-eight of these positive sera were also tested by an anti-HIV-2 Western blot kit (LAV-Blot II) with positive results. The ELISAs based on SBL-6669 and HTLV-IV antigens had a specificity of 99.6% (one false positive among 250 negative sera) whereas the specificity of ELAVIA II was 94.6% using the recommended cut-off value and 98.4% using a higher cut-off value. Another 58 sera from West African patients, clinically suspected of having AIDS or HIV-related disease, were tested for HIV-2/HTLV-IV antibodies by Western blot and by ELISA against SBL-6669 and HTLV-IV antigens; all of the 30 sera which were positive by Western blot were found to be positive in both ELISAs.(ABSTRACT TRUNCATED AT 250 WORDS)
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| 3. |
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| 4. |
- Teriö, H, et al.
(författare)
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Estimation of elastic properties in the urethral flow controlling zone by signal analysis of urodynamic pressure/flow data.
- 1989
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Ingår i: Medical and Biological Engineering and Computing. - 0140-0118 .- 1741-0444. ; 27:3, s. 314-321
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Tidskriftsartikel (refereegranskat)abstract
- When urethral flow is treated as a lossless flow through an elastic tube, the relationship between the detrusor pressure and the urinary flow can be related to the elasticity of the flow-controlling zone of the urethra. A recent analytical method of describing urethral elasticity is implemented on a computer. The function p(Q) = pmo + LmQm is fitted to the recorded pressure/flow data. p(Q) is the detrusor pressure, Q the flow and pmo, m and Lm parameters. The elastic properties are then obtained as p(A) = pmo + KnAn, where p(A) is the static pressure, A the cross-sectional area of the flow-controlling zone and n and Kn calculated parameters. The urodynamic methods used and the computer implementation of the analytical method are described. In obstructed and unobstructed men without neurological symptoms, the elastic properties could be estimated in 94 per cent of the micturitions. The method makes it possible to describe urethral flow properties with Griffiths' model in a standardised way and compare results obtained by different investigators. It is recommended for quantification of urethral obstruction in research and for assessment of borderline cases of obstruction in clinical practice.
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