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A three-dimensional...
A three-dimensional ultrasonic cage for characterization of individual cells
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- Manneberg, Otto (author)
- KTH,Biomedicinsk fysik och röntgenfysik,Biomedical & X-Ray Physics
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- Vanherberghen, Bruno (author)
- KTH,Cellens fysik,Cell Physics
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- Svennebring, Jessica (author)
- KTH,Biomedicinsk fysik och röntgenfysik,Biomedical & X-Ray Physics
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- Hertz, Hans M. (author)
- KTH,Biomedicinsk fysik och röntgenfysik,Biomedical & X-Ray Physics
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- Önfelt, Björn (author)
- Karolinska Institutet,KTH,Cellens fysik,Cell Physics
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- Wiklund, Martin (author)
- KTH,Biomedicinsk fysik och röntgenfysik,Biomedical & X-Ray Physics
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(creator_code:org_t)
- AIP Publishing, 2008
- 2008
- English.
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In: Applied Physics Letters. - : AIP Publishing. - 0003-6951 .- 1077-3118. ; 93, s. 063901-
- Related links:
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http://scitation.aip...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- We demonstrate enrichment, controlled aggregation, and manipulation of microparticles and cells by an ultrasonic cage integrated in a microfluidic chip compatible with high-resolution optical microscopy. The cage is designed as a dual-frequency resonant filleted square box integrated in the fluid channel. Individual particles may be trapped three dimensionally, and the dimensionality of one-dimensional to three-dimensional aggregates can be controlled. We investigate the dependence of the shape and position of a microparticle aggregate on the actuation voltages and aggregate size, and demonstrate optical monitoring of individually trapped live cells with submicrometer resolution.
Subject headings
- NATURVETENSKAP -- Fysik -- Den kondenserade materiens fysik (hsv//swe)
- NATURAL SCIENCES -- Physical Sciences -- Condensed Matter Physics (hsv//eng)
Keyword
- optical manipulation; microfluidic chip; particles; traps
- Biological physics
- Biologisk fysik
Publication and Content Type
- ref (subject category)
- art (subject category)
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