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Increased Risk of S...
Increased Risk of Squamous Cell Carcinoma of the Skin and Lymphoma Among 5,739 Patients with Bullous Pemphigoid: A Swedish Nationwide Cohort Study
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- Albadri, Zeyad (författare)
- Linköpings universitet,Avdelningen för cellbiologi,Medicinska fakulteten
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- Thorslund, Kristofer (författare)
- Karolinska Inst, Sweden
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- Habel, Henrike (författare)
- Karolinska Institutet,Karolinska Inst, Sweden
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- Seifert, Oliver (författare)
- Linköpings universitet,Avdelningen för cellbiologi,Medicinska fakulteten,Div Dermatol & Venereol, Sweden
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- Gronhagen, Carina (författare)
- Lund Univ, Sweden
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(creator_code:org_t)
- 2020
- 2020
- Engelska.
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Ingår i: Acta Dermato-Venereologica. - : ACTA DERMATO-VENEREOLOGICA. - 0001-5555 .- 1651-2057. ; 100
- Relaterad länk:
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https://liu.diva-por... (primary) (Raw object)
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https://doi.org/10.2...
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https://urn.kb.se/re...
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https://doi.org/10.2...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Evidence about the association of bullous pemphigoid and the risk of cancer is conflicting. Patients diagnosed with bullous pemphigoid (n = 5,739) between 2005 and 2016 were matched with a control cohort from the general population (n = 17,168) to estimate their overall and specific risk of cancer. The risk of squamous cell cancer of the skin (cSCC) was increased in patients with bullous pemphigoid (hazard ratio (HR) 1.3; 95% confidence interval (CI) 1.1-1.6). The risk of lymphoma within one year after bullous pemphigoid diagnosis was also increased (HR 3.1; 95% CI 1.3-7.6). While overall cancer risk prior to diagnosis of bullous pemphigoid was similar in cases and controls (prevalence odds ratio (POR) 1.0; 95% CI 0.9-1.0), the risk of male genital cancer within one year prior to diagnosis of bullous pemphigoid was lower in cases (POR 0.4; 95% CI 0.2-0.8). Clinicians must be aware of the increased risk of cSCC and lymphoma in patients with bullous pemphigoid.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Nyckelord
- cancer; epidemiology; bullous pemphigoid; autoimmune diseases; malignancy; skin diseases
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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