Search: id:"swepub:oai:DiVA.org:liu-72017" >
Thoracic epidural a...
Thoracic epidural analgesia or patient-controlled local analgesia for radical retropubic prostatectomy: a randomized, double-blind study
-
- Fant, Federica (author)
- Örebro universitet,Institutionen för hälsovetenskap och medicin,Örebro University
-
- Axelsson, Kjell (author)
- Örebro universitet,Institutionen för hälsovetenskap och medicin,Örebro University
-
- Sandblom, Dag (author)
- Örebro universitet,Institutionen för hälsovetenskap och medicin,Örebro University
-
show more...
-
- Magnuson, A (author)
- Clinical Epidemiology and Biostatistical Unit, Örebro University Hospital, Örebro University, Örebro, Sweden
-
- Andersson, Swen-Olof (author)
- Örebro universitet,Institutionen för hälsovetenskap och medicin,Örebro University
-
- Gupta, Anil (author)
- Örebro universitet,Östergötlands Läns Landsting,Linköpings universitet,Anestesiologi med intensivvård,Hälsouniversitetet,Anestesi- och operationkliniken US,Institutionen för hälsovetenskap och medicin
-
show less...
-
(creator_code:org_t)
- Oxford University Press (OUP), 2011
- 2011
- English.
-
In: British Journal of Anaesthesia. - : Oxford University Press (OUP). - 0007-0912 .- 1471-6771. ; 107:5, s. 782-789
- Related links:
-
http://bjanaesthesia...
-
show more...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
https://urn.kb.se/re...
-
show less...
Abstract
Subject headings
Close
- Background. Postoperative pain after radical retropubic prostatectomy is moderate to severe. The primary aim of this study was to assess whether intra-abdominal local anaesthetics provide similar analgesia compared with thoracic epidural analgesia (TEA). less thanbrgreater than less thanbrgreater thanMethods. Fifty patients, ASA I-II, participated in this prospective, double-blinded study. All patients had TEA. After operation, they were randomized into two groups of 25 patients: Group PCLA (patient-controlled local analgesia): self-administration of 10 ml of ropivacaine 2 mg ml(-1) via the intra-abdominal catheter for 48 h. Group TEA: infusion of 10 ml h(-1) of ropivacaine 1 mg ml(-1), fentanyl 2 mg ml(-1), and epinephrine 2 mg ml 21 epidurally for 48 h. The primary endpoint was pain on coughing at 4 h after operation. Rescue medication was morphine i.v. as required. less thanbrgreater than less thanbrgreater thanResults. Pain on coughing at 4, 24, and 48 h was significantly lower in Group TEA [0 (0-10)] compared with Group PCLA [4 (0-10)] (Pandlt;0.05). Significantly lower pain intensity was also found in Group TEA compared with Group PCLA at the incision site, deep pain, and pain on coughing at 4 and 24 h (Pandlt;0.05). Morphine consumption was significantly greater in Group PCLA [12 (0-46)] compared with Group TEA [0 (0-20)] at 0-48 h after operation [median (range)] (P=0.015). Maximum expiratory pressure was higher in Group TEA compared with Group PCLA at 24 h (Pandlt;0.01). less thanbrgreater than less thanbrgreater thanConclusions. TEA provides superior postoperative pain relief with better preservation of expiratory muscle strength compared with PCLA.
Keyword
- anaesthetics
- local
- analgesia
- epidural
- analgesia
- patient-controlled
- prostatectomy
- retropubic
- MEDICINE
- MEDICIN
- Medicine
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database