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Dementia screening ...
Dementia screening in rural-dwelling Chinese older adults : The utility of a smell test and the self-rated AD8
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Dong, Yi (författare)
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Wang, Yongxiang (författare)
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Liu, Keke (författare)
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Hou, Tingting (författare)
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Han, Xiaolei (författare)
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Cong, Lin (författare)
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Ren, Yifei (författare)
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Zhang, Qinghua (författare)
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Tang, Shi (författare)
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- Ekström, Ingrid, 1988- (författare)
- Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI)
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- Laukka, Erika J. (författare)
- Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI)
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Du, Yifeng (författare)
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- Qiu, Chengxuan (författare)
- Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Shandong University, China
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Ekstrom, R (författare)
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(creator_code:org_t)
- 2021-12-07
- 2022
- Engelska.
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Ingår i: Journal of The American Geriatrics Society. - : Wiley. - 0002-8614 .- 1532-5415. ; 70:4, s. 1106-1116
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Background: Olfactory impairment is associated with dementia in clinical settings. We examined the relationship of olfactory identification function with all-cause dementia, Alzheimer's disease (AD), and vascular dementia (VaD) and assessed the discriminative ability of the Sniffin' Sticks Identification Test (SSIT), the self-rated Ascertain Dementia 8-item Questionnaire (AD8), and their combination for dementia detection among rural-dwelling older adults in China.Methods: This population-based cross-sectional study included 4481 participants (age ≥ 65 years; 56.8% women; 38.1% illiteracy) living in rural communities. The 16-item SSIT was performed to assess olfactory identification function. The self-rated AD8 was administered to participants for cognitive status. We diagnosed dementia, AD, and VaD following the international criteria. Data were analyzed with logistic regression models and receiver operating characteristic curve.Results: Of the 4481 participants, dementia was diagnosed in 139 persons (3.1%), including 92 with AD and 42 with VaD. The SSIT score (range, 0–16) was associated with multiadjusted odds ratios of 0.83 (95% CI: 0.79–0.88) for dementia, 0.84 (0.79–0.90) for AD, and 0.79 (0.71–0.87) for VaD. The area under the curve for the discrimination between participants with and without dementia was 0.73 (95% CI: 0.69–0.77) for SSIT score ≤ 8 alone, 0.86 (0.82–0.89) for self-rated AD8 score ≥ 3 alone, and 0.89 (0.86–0.92) for their combination using a logistic model.Conclusions: Olfactory impairment is a clinical marker for all-cause dementia, AD, and VaD. The smell identification test, in combination with the brief self-rated cognitive screening tool, is accurate for screening dementia among rural-dwelling Chinese older adults with no or limited education.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Geriatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Geriatrics (hsv//eng)
Nyckelord
- dementia
- diagnostic accuracy
- olfaction
- population-based study
- self-rated ascertain dementia 8-item questionnaire
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Dong, Yi
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Wang, Yongxiang
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Liu, Keke
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Hou, Tingting
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Han, Xiaolei
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Cong, Lin
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visa fler...
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Ren, Yifei
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Zhang, Qinghua
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Tang, Shi
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Ekström, Ingrid, ...
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Laukka, Erika J.
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Du, Yifeng
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Qiu, Chengxuan
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Ekstrom, R
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Geriatrik
- Artiklar i publikationen
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Journal of The A ...
- Av lärosätet
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Stockholms universitet
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Karolinska Institutet