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Cardiovascular seco...
Cardiovascular secondary prevention in high-risk patients : a randomized controlled trial sub-study
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- Jakobsson, Stina (författare)
- Umeå universitet,Medicin,Research Unit Östersund
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- Irewall, Anna-Lotta, 1987- (författare)
- Umeå universitet,Medicin,Research Unit Östersund
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- Björklund, Fredrik (författare)
- Umeå universitet,Medicin,Research Unit Östersund
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- Mooe, Thomas (författare)
- Umeå universitet,Medicin,Resarch Unit Östersund
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(creator_code:org_t)
- 2015-10-14
- 2015
- Engelska.
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Ingår i: BMC Cardiovascular Disorders. - : BioMed Central. - 1471-2261 .- 1471-2261. ; 15
- Relaterad länk:
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https://umu.diva-por... (primary) (Raw object)
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https://umu.diva-por...
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https://umu.diva-por...
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https://umu.diva-por...
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https://bmccardiovas...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background: Enhanced cardiovascular secondary preventive follow-up is needed to improve adherence to recommended low-density lipoprotein cholesterol (LDL-C) and blood pressure (BP) levels. Patients with diabetes mellitus (DM) or chronic kidney disease (CKD) have a high risk of recurrent events. Secondary prevention is therefore essential in these patients.Methods: Patients with acute coronary syndrome, stroke, or transient ischemic attack were randomized to nurse-based telephone follow-up (intervention) or usual care (control). LDL-C and BP were measured at 1 month (baseline) and 12 months post-discharge. Intervention patients with above-target values at baseline received medication titration to achieve treatment goals. Values measured for control patients were given to the patient’s general practitioner for assessment.Results: The final analyses included 225 intervention and 215 control patients with DM or CKD. Among patients with above-target baseline values, the following 12-month values were recorded for intervention and control patients, respectively: LDL-C, 2.2 versus 3.0 mmol/L (p < 0.001); and median systolic BP (SBP), 140 versus 145 mmHg (p = 0.26). Among patients with above-target values at baseline, 52.3% of intervention patients reached target LDL-C values at 12 months versus 21.3% of control patients (absolute difference of 30.9%, 95% CI 16.1 to 43.8%), and there was a non-significant trend of more intervention patients reaching target SBP (49.4% versus 36.8%; absolute difference of 12.6%, 95% CI -1.7 to 26.2%).Conclusions: Cardiovascular secondary prevention with nurse-based telephone follow-up was more effective than usual care in improving LDL-C levels 12 months after discharge for patients with DM or CKD.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- acute coronary syndrome
- myocardial infarction
- stroke
- transient ischemic attack
- diabetes mellitus
- chronic renal insufficiency
- secondary prevention
- cardiovascular disease
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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