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Executive function ...
Executive function in HIV-affected children and adolescents : a systematic review and meta-analyses
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- Rowe, Kirsten (författare)
- Child and Adolescent Psychiatry, Department of Psychiatry, University of Oxford, Oxford, United Kingdom; MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, University of Witwatersrand, Johannesburg, South Africa
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- Buivydaite, Ruta (författare)
- Child and Adolescent Psychiatry, Department of Psychiatry, University of Oxford, Oxford, United Kingdom
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- Heinsohn, Torben (författare)
- Medical School, Medical Sciences Division, University of Oxford, Oxford, United Kingdom
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- Rahimzadeh, Mana (författare)
- Medical School, Medical Sciences Division, University of Oxford, Oxford, United Kingdom
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- Wagner, Ryan G. (författare)
- Umeå universitet,Institutionen för epidemiologi och global hälsa,MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, University of Witwatersrand, Johannesburg, South Africa
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- Scerif, Gaia (författare)
- Developmental Cognitive Neuroscience, Department of Experimental Psychology, University of Oxford, Oxford, United Kingdom
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- Stein, Alan (författare)
- Child and Adolescent Psychiatry, Department of Psychiatry, University of Oxford, Oxford, United Kingdom; MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, University of Witwatersrand, Johannesburg, South Africa
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(creator_code:org_t)
- 2021-03-25
- 2021
- Engelska.
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Ingår i: AIDS Care. - : Routledge. - 0954-0121 .- 1360-0451. ; 33:7, s. 833-857
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- This review aimed to determine: whether EF is affected in children and adolescents (2–24-years-old) with perinatal HIV infection, perinatal HIV exposure without infection, and behaviourally acquired HIV. A systematic review (PROSPERO number: CRD42017067813) was conducted using 11 electronic databases (01.01.1981–09.07.2019) and 8 conference websites. Primary quantitative studies with EF scores on cognitive tasks and/or behavioural report measures were included. Meta-analyses were performed by EF subtype and subpopulations compared. 1789 records were found. Sixty-one studies were included in the narrative synthesis; 32 (N = 7884 participants) were included in meta-analyses. There was a distinct pattern of reduced EF in those with perinatal HIV infection on antiretroviral therapy compared to controls: pooled effect sizes were largest for verbal and visuospatial working memory, with smaller effects on planning, inhibitory control and set-shifting. Data were limited for other HIV-affected subpopulations. Perinatal HIV infection is associated with reduced EF with varying effect sizes for the different EF subtypes.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Nyckelord
- executive function
- HIV-associated neurocognitive disorder
- neurodevelopment
- paediatric HIV
- Perinatally acquired HIV
- systematic review
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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