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Chlamydia trachomat...
Chlamydia trachomatis and Mycoplasma genitalium plasma antibodies in relation to epithelial ovarian tumors
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- Idahl, Annika, 1965- (författare)
- Umeå universitet,Obstetrik och gynekologi,Ovarian Cancer Research Group
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- Lundin, Eva (författare)
- Umeå universitet,Patologi,Ovarian Cancer Research Group
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- Jurstrand, Margaretha (författare)
- Clinical Research Centre, Örebro University Hospital, Örebro, Sweden
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- Kumlin, Urban (författare)
- Umeå universitet,Virologi
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- Elgh, Fredrik, 1957- (författare)
- Umeå universitet,Avdelningen för virologi
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- Ohlson, Nina (författare)
- Umeå universitet,Patologi
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- Ottander, Ulrika (författare)
- Umeå universitet,Obstetrik och gynekologi,Ovarian Cancer Research Group
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(creator_code:org_t)
- Hindawi Publishing Corporation, 2011
- 2011
- Engelska.
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Ingår i: Infectious diseases in obstetrics and gynecology. - : Hindawi Publishing Corporation. - 1064-7449 .- 1098-0997. ; 2011
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Objective: To assess associations of Chlamydia trachomatis and Mycoplasma genitalium antibodies with epithelial ovarian tumors.Methods: Plasma samples from 291 women, undergoing surgery due to suspected ovarian pathology, were analyzed with respect to C. trachomatis IgG and IgA, chlamydial Heat Shock Protein 60-1 (cHSP60-1) IgG and M. genitalium IgG antibodies. Women with borderline tumors (), ovarian carcinoma (), or other pelvic malignancies () were matched to four healthy controls each.Results: Overall, there were no associations of antibodies with EOC. However, chlamydial HSP60-1 IgG antibodies were associated with type II ovarian cancer () in women with plasma samples obtained >1 year prior to diagnosis (). M. genitalium IgG antibodies were associated with borderline ovarian tumors ().Conclusion: Chlamydial HSP60-1 IgG and M. genitalium IgG antibodies are in this study associated with epithelial ovarian tumors in some subsets, which support the hypothesis linking upper-genital tract infections and ovarian tumor development.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)
Nyckelord
- borderline tumors
- Chlamydia trachomatis
- cHSP60
- Mycoplasma genitalium
- ovarian cancer
- Obstetrics and gynaecology
- Obstetrik och gynekologi
- obstetrik och gynekologi
- Obstetrics and Gynaecology
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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