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Sulfonimidamides in...
Sulfonimidamides in Medicinal and Agricultural Chemistry
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- Chinthakindi, Praveen Kumar (författare)
- University of KwaZulu Natal, Durban, South Africa
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- Thota, Niranjan (författare)
- University of KwaZulu Natal, Durban, South Africa
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- Govender, Thavendran (författare)
- University of KwaZulu Natal, Durban, South Africa
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- Kruger, Hendrik G. (författare)
- University of KwaZulu Natal, Durban, South Africa
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- Arvidsson, Per I. (författare)
- Karolinska Institutet
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Naicker, T (författare)
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(creator_code:org_t)
- 2017-02-23
- 2017
- Engelska.
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Ingår i: Angewandte Chemie International Edition. - : Wiley. - 1433-7851. ; 56:15, s. 4100-4109
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- The synthesis and evaluation of structural analogues and isosteres are of central importance in medicinal and agricultural chemistry. The sulfonamide functional group represents one of the most important amide isosteres in contemporary drug design, and about 500 such compounds have overcome both the pharmacological and regulatory hurdles that precede studies in humans. The mono aza analogues of sulfonamides, that is, sulfonimidamides, are rapidly gaining popularity as a novel functional group among synthetic chemists involved in the design of biologically active compounds for both pharmaceutical and agrochemical applications. Herein, we review these recent developments to showcase the promise of this functional group.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Läkemedelskemi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Medicinal Chemistry (hsv//eng)
- NATURVETENSKAP -- Kemi -- Organisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Organic Chemistry (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Kemiteknik -- Farmaceutisk synteskemi (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Chemical Engineering -- Pharmaceutical Chemistry (hsv//eng)
Nyckelord
- Sulfonimidamide
- Medicinal Chemistry
- Läkemedelskemi
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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