Sökning: id:"swepub:oai:DiVA.org:uu-423365" >
Evolutionary geneti...
Evolutionary genetics of canine respiratory coronavirus and recent introduction into Swedish dogs
-
- Wille, Michelle (författare)
- Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi
-
- Johansson Wensman, Jonas (författare)
- Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för kliniska vetenskaper (KV),Department of Clinical Sciences,Swedish Univ Agr Sci, Dept Clin Sci, Box 7054, S-75007 Uppsala, Sweden.
-
- Larsson, Simon (författare)
- Swedish Univ Agr Sci, Dept Biomed Sci & Vet Publ Hlth, Sect Virol, Box 7028, S-75007 Uppsala, Sweden.;Nanyang Technol Univ, Lee Kong Chian Sch Med, 59 Nanyang Dr,Expt Med Bldg, Singapore 636921, Singapore.
-
visa fler...
-
- van Damme, Renaud (författare)
- Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för husdjursgenetik (HGEN),Department of Animal Breeding and Genetics,Swedish Univ Agr Sci, SLU Global Bioinformat Ctr, Dept Anim Breeding & Genet, Box 7023, S-75007 Uppsala, Sweden.
-
- Theelke, Anna-Karin (författare)
- Natl Vet Inst, Dept Microbiol, S-75189 Uppsala, Sweden.
-
- Hayer, Juliette (författare)
- Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för husdjursgenetik (HGEN),Department of Animal Breeding and Genetics,Swedish Univ Agr Sci, SLU Global Bioinformat Ctr, Dept Anim Breeding & Genet, Box 7023, S-75007 Uppsala, Sweden.
-
- Malmberg, Maja (författare)
- Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Inst för biomedicin och veterinär folkhälsovetenskap,Institutionen för husdjursgenetik (HGEN),Department of Biomedical Science and Veterinary Public Health,Department of Animal Breeding and Genetics,Swedish Univ Agr Sci, Dept Biomed Sci & Vet Publ Hlth, Sect Virol, Box 7028, S-75007 Uppsala, Sweden.;Swedish Univ Agr Sci, SLU Global Bioinformat Ctr, Dept Anim Breeding & Genet, Box 7023, S-75007 Uppsala, Sweden.
-
visa färre...
-
(creator_code:org_t)
-
- Elsevier BV, 2020
- 2020
- Engelska.
-
Ingår i: Infection, Genetics and Evolution. - : Elsevier BV. - 1567-1348 .- 1567-7257. ; 82
- Relaterad länk:
-
https://doi.org/10.1...
-
visa fler...
-
https://pub.epsilon.... (primary) (Raw object) (free)
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
https://res.slu.se/i...
-
visa färre...
Abstract
Ämnesord
Stäng
- Canine respiratory coronavirus (CRCoV) has been identified as a causative agent of canine infectious respiratory disease, an upper respiratory infection affecting dogs. The epidemiology is currently opaque, with an unclear understanding of global prevalence, pathology, and genetic characteristics. In this study, Swedish privately-owned dogs with characteristic signs of canine infectious respiratory disease (n = 88) were screened for CRCoV and 13 positive samples (14.7%, 8.4-23.7% [95% confidence interval (CI)]) were further sequenced. Sequenced Swedish CRCoV isolates were highly similar despite being detected in dogs living in geographically distant locations and sampled across 3 years (2013-2015). This is due to a single introduction into Swedish dogs in approximately 2010, as inferred by time structured phylogeny. Unlike other CRCoVs, there was no evidence of recombination in Swedish CRCoV viruses, further supporting a single introduction. Finally, there were low levels of polymorphisms, in the spike genes. Overall, we demonstrate that there is little diversity of CRCoV which is endemic in Swedish dogs.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
- LANTBRUKSVETENSKAPER -- Veterinärmedicin -- Klinisk vetenskap (hsv//swe)
- AGRICULTURAL SCIENCES -- Veterinary Science -- Clinical Science (hsv//eng)
- LANTBRUKSVETENSKAPER -- Veterinärmedicin -- Patobiologi (hsv//swe)
- AGRICULTURAL SCIENCES -- Veterinary Science -- Pathobiology (hsv//eng)
Nyckelord
- Canine infectious respiratory disease
- Canine respiratory coronavirus
- CRCoV
- Coronavirus
- Evolutionary genetics
- Kennel cough
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas