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Sökning: id:"swepub:oai:gup.ub.gu.se/294102" > Predicting mental h...

Predicting mental health problems in adolescence using machine learning techniques

Tate, A. E. (författare)
Karolinska Institutet
McCabe, R. C. (författare)
Spotify, Stockholm, Sweden
Larsson, Henrik, 1975- (författare)
Örebro universitet,Institutionen för medicinska vetenskaper,Department of Medical Epidemiology and Biostatics, Karolinska Institutet, Stockholm, Sweden
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Lundström, Sebastian (författare)
Gothenburg University,Göteborgs universitet,Centrum för etik, juridik och mental hälsa,Centre for Ethics, Law, and Mental Health,Centre for Ethics, Law and Mental Health (CELAM), University of Gothenburg, Gothenburg, Swede; Gillberg Neuropsychiatry Centre, University of Gothenburg, Gothenburg, Sweden
Lichtenstein, P. (författare)
Karolinska Institutet
Kuja-Halkola, R. (författare)
Karolinska Institutet
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 (creator_code:org_t)
2020-04-06
2020
Engelska.
Ingår i: PLoS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 15:4
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Background Predicting which children will go on to develop mental health symptoms as adolescents is critical for early intervention and preventing future, severe negative outcomes. Although many aspects of a child's life, personality, and symptoms have been flagged as indicators, there is currently no model created to screen the general population for the risk of developing mental health problems. Additionally, the advent of machine learning techniques represents an exciting way to potentially improve upon the standard prediction modelling technique, logistic regression. Therefore, we aimed to I.) develop a model that can predict mental health problems in mid-adolescence II.) investigate if machine learning techniques (random forest, support vector machines, neural network, and XGBoost) will outperform logistic regression. Methods In 7,638 twins from the Child and Adolescent Twin Study in Sweden we used 474 predictors derived from parental report and register data. The outcome, mental health problems, was determined by the Strengths and Difficulties Questionnaire. Model performance was determined by the area under the receiver operating characteristic curve (AUC). Results Although model performance varied somewhat, the confidence interval overlapped for each model indicating non-significant superiority for the random forest model (AUC = 0.739, 95% CI 0.708-0.769), followed closely by support vector machines (AUC = 0.735, 95% CI 0.707-0.764). Conclusion Ultimately, our top performing model would not be suitable for clinical use, however it lays important groundwork for future models seeking to predict general mental health outcomes. Future studies should make use of parent-rated assessments when possible. Additionally, it may not be necessary for similar studies to forgo logistic regression in favor of other more complex methods.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Psykiatri (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Psychiatry (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)

Nyckelord

childhood
symptoms
children
subthreshold
impulsivity
disorders
strengths
outcomes
suicide
twin
Science & Technology - Other Topics

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