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The Genetics of Uri...
The Genetics of Urinary Tract Infections and the Innate Defense of the Kidney and Urinary tract
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- Ambite, Ines (författare)
- Lund University,Lunds universitet,Avdelningen för mikrobiologi, immunologi och glykobiologi - MIG,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Microbiology, Immunology and Glycobiology - MIG,Department of Laboratory Medicine,Faculty of Medicine
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- RYDSTRÖM, GUSTAV (författare)
- Lund University,Lunds universitet,Avdelningen för mikrobiologi, immunologi och glykobiologi - MIG,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Microbiology, Immunology and Glycobiology - MIG,Department of Laboratory Medicine,Faculty of Medicine
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- Schwaderer, Andrew L (författare)
- Ohio State University
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- Hains, David S (författare)
- University of Tennessee
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(creator_code:org_t)
- 2015-08-13
- 2016
- Engelska.
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Ingår i: Journal of pediatric genetics. - : Georg Thieme Verlag KG. - 2146-4596 .- 2146-460X. ; 5:1, s. 25-32
- Relaterad länk:
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http://dx.doi.org/10...
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https://europepmc.or...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The urinary tract is a sterile organ system. Urinary tract infections (UTIs) are common and often serious infections. Research has focused on uropathogen, environment, and host factors leading to UTI pathogenesis. A growing body of evidence exists implicating genetic factors that can contribute to UTI risks. In this review, we highlight genetic variations in aspects of the innate immune system critical to the host response to uropathogens. This overview includes genetic variations in pattern recognition receptor molecules, chemokines/cytokines, and neutrophil activation. We also comprehensively cover murine knockout models of UTI, genetic variations involved in renal scarring as a result of ascending UTIs, and asymptomatic bacteriuria.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
Nyckelord
- Journal Article
- Review
Publikations- och innehållstyp
- for (ämneskategori)
- ref (ämneskategori)
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