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A cross-sectional s...
A cross-sectional study of the Birmingham Vasculitis Activity Score version 3 in systemic vasculitis.
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Suppiah, Ravi (författare)
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Mukhtyar, Chetan (författare)
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Flossmann, Oliver (författare)
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Alberici, Federico (författare)
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Baslund, Bo (författare)
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Batra, Rajbir (författare)
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Brown, Denise (författare)
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Holle, Julia (författare)
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Hruskova, Zdenka (författare)
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Jayne, David R W (författare)
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Judge, Andrew (författare)
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Little, Mark A (författare)
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Palmisano, Alessandra (författare)
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Stegeman, Coen (författare)
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Tesar, Vladimir (författare)
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Vaglio, Augusto (författare)
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- Westman, Kerstin (författare)
- Lund University,Lunds universitet,Njurmedicin,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Nephrology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine
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Luqmani, Raashid (författare)
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(creator_code:org_t)
- 2010-12-13
- 2011
- Engelska.
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Ingår i: Rheumatology (Oxford, England). - : Oxford University Press (OUP). - 1462-0332 .- 1462-0324. ; 50, s. 899-905
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http://dx.doi.org/10... (free)
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- Objective. Assessment of disease activity in vasculitis can be achieved using the BVAS, a clinical checklist of relevant symptoms, signs and features of active disease. The aim of this study was to revalidate the BVAS version 3 (BVAS v. 3) in a cohort of patients with systemic vasculitis. Methods. A total of 238 patients with vasculitis from seven countries in Europe were evaluated at a single time point. Spearman's correlation coefficients were calculated between BVAS v. 3 scores, vasculitis activity index (VAI), physician's global assessment (PGA), the physician's treatment decision, CRP and the vasculitis damage index (VDI) to demonstrate that the BVAS v. 3 measures disease activity. Results. WG (63%), Churg-Strauss syndrome (9%) and microscopic polyangiitis (9%) were the most common diagnoses. The BVAS v. 3 showed convergent validity with the VAI [ρ = 0.82 (95% CI 0.77, 0.85)], PGA [ρ = 0.85 (95% CI 0.81, 0.88)] and the physician's treatment decision [ρ = 0.54 (95% CI 0.44, 0.62)]. There was little or no correlation between BVAS v. 3 and the CRP level [ρ = 0.18 (95% CI 0.05, 0.30)] or with the VDI [ρ = -0.10 (95% CI 0.22, 0.03)]. The inter-observer reliability was very high with an intra-class correlation coefficient (ICC) of 0.996 (95% CI 0.990, 0.998) for the total BVAS v. 3 score. Conclusion. The BVAS v. 3 has been evaluated in a large cohort of patients with vasculitis and the important properties of the tool revalidated. This study increases the utility of the BVAS v. 3 in different populations of patients with systemic vasculitis.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)
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- Av författaren/redakt...
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Suppiah, Ravi
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Mukhtyar, Chetan
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Flossmann, Olive ...
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Alberici, Federi ...
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Baslund, Bo
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Batra, Rajbir
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visa fler...
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Brown, Denise
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Holle, Julia
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Hruskova, Zdenka
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Jayne, David R W
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Judge, Andrew
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Little, Mark A
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Palmisano, Aless ...
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Stegeman, Coen
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Tesar, Vladimir
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Vaglio, Augusto
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Westman, Kerstin
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Luqmani, Raashid
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visa färre...
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Lunds universitet