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Combined diffusion-...
Combined diffusion-relaxometry microstructure imaging : Current status and future prospects
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- Slator, Paddy J. (författare)
- University College London
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- Palombo, Marco (författare)
- University College London
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- Miller, Karla L. (författare)
- University of Oxford
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- Westin, Carl Fredrik (författare)
- Harvard Medical School
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- Laun, Frederik (författare)
- University Hospital Erlangen
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- Kim, Daeun (författare)
- University of Southern California
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- Haldar, Justin P. (författare)
- University of Southern California
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- Benjamini, Dan (författare)
- Uniformed Services University of the Health Sciences,National Institute of Child Health and Human Development
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- Lemberskiy, Gregory (författare)
- NYU Grossman School of Medicine
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- de Almeida Martins, Joao P. (författare)
- Lund University,Lunds universitet,Fysikalisk kemi,Enheten för fysikalisk och teoretisk kemi,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Physical Chemistry,Physical and theoretical chemistry,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH,St. Olav’s University Hospital
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- Hutter, Jana (författare)
- King's College London
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(creator_code:org_t)
- 2021-08-19
- 2021
- Engelska 25 s.
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Ingår i: Magnetic Resonance in Medicine. - : Wiley. - 0740-3194 .- 1522-2594. ; 86:6, s. 2987-3011
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http://dx.doi.org/10... (free)
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Abstract
Ämnesord
Stäng
- Microstructure imaging seeks to noninvasively measure and map microscopic tissue features by pairing mathematical modeling with tailored MRI protocols. This article reviews an emerging paradigm that has the potential to provide a more detailed assessment of tissue microstructure—combined diffusion-relaxometry imaging. Combined diffusion-relaxometry acquisitions vary multiple MR contrast encodings—such as b-value, gradient direction, inversion time, and echo time—in a multidimensional acquisition space. When paired with suitable analysis techniques, this enables quantification of correlations and coupling between multiple MR parameters—such as diffusivity, (Formula presented.), (Formula presented.), and (Formula presented.). This opens the possibility of disentangling multiple tissue compartments (within voxels) that are indistinguishable with single-contrast scans, enabling a new generation of microstructural maps with improved biological sensitivity and specificity.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
Nyckelord
- diffusion
- multidimensional MRI
- quantitative MRI
- relaxometry
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- ref (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Slator, Paddy J.
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Palombo, Marco
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Miller, Karla L.
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Westin, Carl Fre ...
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Laun, Frederik
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Kim, Daeun
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visa fler...
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Haldar, Justin P ...
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Benjamini, Dan
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Lemberskiy, Greg ...
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de Almeida Marti ...
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Hutter, Jana
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Radiologi och bi ...
- Artiklar i publikationen
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Magnetic Resonan ...
- Av lärosätet
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Lunds universitet