Search: id:"swepub:oai:lup.lub.lu.se:d8633dff-359c-4f2d-a9e7-88fc05a543eb" >
Time to epileptifor...
Time to epileptiform activity and EEG background recovery are independent predictors after cardiac arrest
-
- Westhall, E. (author)
- Lund University,Lunds universitet,Klinisk neurofysiologi,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Clinical Neurophysiology,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital,Lund Univ, Sweden
-
- Rosén, I. (author)
- Lund University,Lunds universitet,Klinisk neurofysiologi,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Clinical Neurophysiology,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital,Lund Univ, Sweden
-
- Rundgren, M. (author)
- Lund University,Lunds universitet,Anestesiologi och intensivvård,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Anesthesiology and Intensive Care,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital,Lund Univ, Sweden
-
show more...
-
- Bro-Jeppesen, J. (author)
- University of Copenhagen,Rigshosp, Denmark; Univ Copenhagen, Denmark
-
- Kjaergaard, J. (author)
- University of Copenhagen,Rigshosp, Denmark; Univ Copenhagen, Denmark
-
- Hassager, C. (author)
- University of Copenhagen,Rigshosp, Denmark; Univ Copenhagen, Denmark
-
- Lindehammar, Hans (author)
- Linköpings universitet,Linköping University,Avdelningen för neuro- och inflammationsvetenskap,Medicinska fakulteten,Region Östergötland, Neurofysiologiska kliniken US
-
- Horn, J. (author)
- Academic Medical Center of University of Amsterdam (AMC),Univ Amsterdam, Netherlands
-
- Ullén, S. (author)
- Skåne University Hospital,Skane Univ Hosp, Sweden
-
- Nielsen, N. (author)
- Helsingborg Hospital,Helsingborg Hosp, Sweden
-
- Friberg, H. (author)
- Lund University,Lunds universitet,Anestesiologi och intensivvård,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Anesthesiology and Intensive Care,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital,Lund Univ, Sweden
-
- Cronberg, T. (author)
- Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital,Lund Univ, Sweden
-
show less...
-
(creator_code:org_t)
- Elsevier BV, 2018
- 2018
- English 9 s.
-
In: Clinical Neurophysiology. - : Elsevier BV. - 1388-2457 .- 1872-8952. ; 129:8, s. 1660-1668
- Related links:
-
http://dx.doi.org/10...
-
show more...
-
https://lup.lub.lu.s...
-
https://doi.org/10.1...
-
https://urn.kb.se/re...
-
show less...
Abstract
Subject headings
Close
- Objective: Investigate the temporal development of EEG and prognosis. Methods: Prospective observational substudy of the Target Temperature Management trial. Six sites performed simplified continuous EEG-monitoring (cEEG) on comatose patients after cardiac arrest, blinded to treating physicians. We determined time-points of recovery of a normal-voltage continuous background activity and the appearance of an epileptiform EEG, defined as abundant epileptiform discharges, periodic/rhythmic discharges or electrographic seizure activity. Results: 134 patients were included, 65 had a good outcome. Early recovery of continuous background activity (within 24 h) occurred in 72 patients and predicted good outcome since 55 (76%) had good outcome, increasing the odds for a good outcome seven times compared to a late background recovery. Early appearance of an epileptiform EEG occurred in 38 patients and 34 (89%) had a poor outcome, increasing the odds for a poor outcome six times compared to a late debut. The time to background recovery and the time to epileptiform activity were highly associated with outcome and levels of neuron-specific enolase. Multiple regression analysis showed that both variables were independent predictors. Conclusions: Time to epileptiform activity and background recovery are independent prognostic indicators. Significance: Patients with early background recovery combined with late appearance of epileptiform activity may have a good outcome.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Keyword
- Cardiac arrest
- Coma
- Continuous EEG monitoring
- EEG
- Prognosis
- Status epilepticus
- EEG; Continuous EEG monitoring; Prognosis; Status epilepticus; Coma; Cardiac arrest
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
To the university's database
- By the author/editor
-
Westhall, E.
-
Rosén, I.
-
Rundgren, M.
-
Bro-Jeppesen, J.
-
Kjaergaard, J.
-
Hassager, C.
-
show more...
-
Lindehammar, Han ...
-
Horn, J.
-
Ullén, S.
-
Nielsen, N.
-
Friberg, H.
-
Cronberg, T.
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Basic Medicine
-
and Neurosciences
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Neurology
- Articles in the publication
-
Clinical Neuroph ...
- By the university
-
Lund University
-
Linköping University