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Analytical Evaluation of GeneXpert CT/NG, the First Genetic Point-of-Care Assay for Simultaneous Detection of Neisseria gonorrhoeae and Chlamydia trachomatis
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- Tabrizi, Sepehr N. (author)
- Dept Microbiol & Infect Dis, Royal Womens Hosp, Parkville Vic, Australia; Dept Obstet & Gynaecol, Royal Womens Hosp, Univ Melbourne, Parkville Vic, Australia; Murdoch Childrens Res Inst, Parkville Vic, Australia
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- Unemo, Magnus (author)
- Region Örebro län,Dept Lab Med, WHO Collaborating Ctr Gonorrhoea & Other STIs, Örebro University Hospital, Örebro, Sweden
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- Golparian, Daniel, 1984- (author)
- Dept Lab Med, WHO Collaborating Ctr Gonorrhoea & Other STIs, Örebro University Hospital, Örebro, Sweden
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- 2013
- 2013
- English.
- In: Journal of Clinical Microbiology. - 0095-1137 .- 1098-660X. ; 51:6, s. 1945-1947
- Journal article (peer-reviewed)
Abstract
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- GeneXpert CT/NG was evaluated with 372 characterized bacterial strains. Sensitivity of 10 genome copies/reaction was obtained for both agents. Four Neisseria mucosa and two Neisseria subflava isolates were positive for one of two gonococcal targets; however, the assay flagged all as negative. The assay was analytically highly sensitive and specific.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Mikrobiologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Microbiology in the medical area (hsv//eng)
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- art (subject category)
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