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Efficacy of the nov...
Efficacy of the novel topical antimicrobial agent pxl150 in a mouse model of surgical site infections
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- Håkansson, Joakim (författare)
- RISE,Medicinteknik,Pergamum AB, Sweden
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- Björn, Camilla (författare)
- RISE,Medicinteknik,Pergamum AB, Sweden
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- Lindgren, Kerstin (författare)
- Pergamum AB, Sweden
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- Sjöström, Emma (författare)
- Pergamum AB, Sweden
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- Sjöstrand, Veronika (författare)
- Pergamum AB, Sweden
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- Mahlapuu, Margit (författare)
- Pergamum AB, Sweden
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(creator_code:org_t)
- 2014
- 2014
- Engelska.
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Ingår i: Antimicrobial Agents and Chemotherapy. - 0066-4804 .- 1098-6596. ; 58:5, s. 2982-2984
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Antimicrobial peptides have recently emerged as a promising new group to be evaluated in the therapeutic intervention of infectious diseases. This study evaluated the anti-infectious effect of the short, synthetic, broad-spectrum antimicrobial peptide PXL150 in a mouse model of staphylococcal surgical site infections. We found that administration of PXL150, formulated in an aqueous solution or in a hydroxypropyl cellulose gel, significantly reduced the bacterial counts in the wound compared with placebo treatment, warranting further investigations of the potential of this peptide as a novel local treatment of microbial infections.
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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