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Deletion of the mitochondrial Pim1/Lon protease in yeast results in accelerated aging and impairment of the proteasome

Erjavec, Nika, 1977 (author)
Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology
Bayot, A. (author)
Gareil, M. (author)
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Camougrand, N. (author)
Nyström, Thomas, 1960 (author)
Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology
Friguet, B. (author)
Bulteau, A. L. (author)
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 (creator_code:org_t)
Elsevier BV, 2013
2013
English.
In: Free Radical Biology and Medicine. - : Elsevier BV. - 0891-5849. ; 56, s. 9-16
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • The Saccharomyces cerevisiae homolog of the ATP-dependent Lon protease, Pim1p, is essential for

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)

Keyword

Pim1/Lon protease
Mitochondria
Protein quality control
Oxidized protein
Proteasome
Free
oxidative stress
saccharomyces-cerevisiae
quality-control
lon
protease
damaged proteins
oxidized proteins
20s proteasome
life-span
degradation
maintenance

Publication and Content Type

ref (subject category)
art (subject category)

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