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The prevalence of p...
The prevalence of prolonged QTc increases by GOLD stage, and is associated with worse survival among subjects with COPD
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- Nilsson, Ulf (författare)
- Umeå universitet,Avdelningen för medicin
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- Kanerud, I. (författare)
- Umeå universitet,Avdelningen för medicin
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- Diamant, Ulla-Britt (författare)
- Umeå universitet,Avdelningen för medicin
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- Blomberg, Anders, 1961- (författare)
- Umeå universitet,Avdelningen för medicin
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- Eriksson, Berne (författare)
- Gothenburg University,Göteborgs universitet,Krefting Research Centre
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- Lindberg, Anne (författare)
- Umeå universitet,Avdelningen för medicin
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(creator_code:org_t)
- Elsevier BV, 2019
- 2019
- Engelska.
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Ingår i: Heart & Lung. - : Elsevier BV. - 0147-9563 .- 1527-3288. ; 48:2, s. 148-154
- Relaterad länk:
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background: The role of QTc-prolongation, in relation to the increased mortality in COPD, is unclear. Objectives: To estimate the prevalence and prognostic impact, assessed as mortality, of QTc-prolongation in COPD, restrictive spirometric pattern (RSP), and normal lung function (NLF), respectively. Methods: All individuals (n = 993) with COPD and age- and sex-matched non-obstructive referents were identified from well-defined population-based cohorts examined in Northern Sweden in 2002-04. In 2005, the study-sample was invited to re-examination including ECG; QTc was calculated and mortality data collected until 31st December 2010. Results: The prevalence of QTc-prolongation was higher among people with RSP than among those with NLF and, although similar in NLF and COPD, the prevalence increased by COPD-severity. Among participants with COPD, those with QTc prolongation had higher mortality than those with normal QTc, while no such differences were found among participants with NLF or RSP. Conclusion: Among participants with COPD, the prevalence of QTc-prolongation increased by disease-severity and was associated with mortality. (C) 2018 Elsevier Inc. All rights reserved.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
Nyckelord
- Epidemiology
- Comorbidity
- Cardiology
- Electrocardiogram
- Pulmonary disease
- Chronic obstructive
- obstructive lung-disease
- sudden cardiac death
- risk-factors
- pulmonary-disease
- interval
- mortality
- duration
- electrocardiography
- recommendations
- underdiagnosis
- Cardiovascular System & Cardiology
- Nursing
- Respiratory System
- ewart ag
- 1995
- respiratory medicine
- v89
- p79
- Epidemiology
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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