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Sökning: WFRF:(Jin Quan) > (2020-2023)

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11.
  • Jin, Quan, 1983, et al. (författare)
  • The influence of indoor environmental quality and workspace design on employees’ health and work performance
  • 2020
  • Ingår i: Proceedings of the Transdisciplinary Workplace Research (TWR) Conference 2020. ; , s. 396-403
  • Konferensbidrag (refereegranskat)abstract
    • Human health and well-being have gained growing attention in the societal debate as well as in research. It is widely acknowledged that employees’ health and well-being contribute to a decent work environment which can positively contribute to economic benefits for the employers, the social-welfare and health system as well as the building owners. However, the office environment is complex and constitutes of various factors affecting employees’ health and well-being, for example, indoor climate, architectural design, and social work environment. Therefore, this paper will focus on indoor environmental quality (IEQ) and workplace design, and their influence on employees’ health and work performance. A multi-disciplinary approach is developed integrating the subjective survey, semi-structured interview, and physical measurement for an in-depth investigation of the physical office environment and employees’ self-reported health and work performance. A large office building with BREEAM certification has been studied at the end of summer in 2019. In total, 160 employees were involved by an online-based survey and individual interview and workshop. The main aspects of IEQ were measured, including the thermal environment, air quality, acoustic and lighting. The correlations between IEQ and workspace design factors and 5-symptom based self-reported health and self-reported work performance concerning self-evaluation and leader’s feedback were studied. Results show that physical office environment shows a large association with self-reported health and self-reported work performance. IEQ factors of air quality and relative humidity are significantly correlated with PSI. Size of individual workspace and aesthetic appearance of the office gain the highest correlation with self-reported health status among the factors of workspace design. Noise and artificial lights are studied to be significantly associated with work performance, and distance between work desks is largely associated with work performance. Considering the needs of employees on the physical office environment, air temperature, air quality and availability to work concentrated still underperform but perceived as highly important by the employees. The study made efforts to study the complex factors existing in the office environment with a multi-disciplinary approach, which can be utilized in other case studies to evaluate office environment and identify the key factors. Thus, the study made it possible to review and compare the influence of physical environment factors affecting employees’ health and well-being. The data collected will contribute to an office database which is under development by the authors.
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12.
  • Jin, Quan, 1983, et al. (författare)
  • Theory of Attractive Quality: Occupant satisfaction with indoor environmental quality at workplaces
  • 2021
  • Ingår i: A Handbook of Theories on Designing Alignment Between People and the Office Environment. - London : Routledge. ; , s. 148-156
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
    • To improve employees’ comfort, health and productivity, indoor environmental quality (IEQ) is one of the most significant aspects of concern in the workplace. In future office buildings, IEQ is not only to meet the basic requirement of hygiene and physiological needs but also to motivate and lift occupants’ satisfaction. This chapter will introduce the attractive quality theory as well as the Kano model and its application in the field of indoor environment science on occupant satisfaction with IEQ and the research methods at workplaces. The chapter will also discuss the limitation of the theory and future research needs to utilise and verify the Kano model.
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13.
  • Liang, Wenbiao, et al. (författare)
  • Synthesis of single-crystal LiNi0.8Co0.1Mn0.1O2 materials for Li-ion batteries by microfluidic technology
  • 2023
  • Ingår i: Chemical Engineering Journal. - : Elsevier. - 1385-8947 .- 1873-3212. ; 464
  • Tidskriftsartikel (refereegranskat)abstract
    • Single-crystal LiNixMnyCo1-x-yO2 (SC-NMC) cathode with electro-chemo-mechanically compliant microstructure is regarded as a promising candidate for high-energy-density lithium ion battery. However, the research of Ni-rich SC-NCM still lags behind its corresponding polycrystalline cathode materials, mainly due to the difficulties in synthesis. Herein, the single-crystal LiNi0.8Mn0.1Co0.1O2 cathode (SC-NCM811) was successfully synthesized by microfluidic technology combined with the solid-state lithiation process. The nano-sized Ni0.8C- o0.1Mn0.1(OH)2 precursor prepared via microfluidic technology enhances its accessibility to lithium salts, thus exhibiting high chemical activity for lithiation reaction. As a result, the optimized SC-NCM811 cathode shows relatively small-scale grain size (<3 mu m), low cation mixing and well layered structure, which is beneficial to electrochemical kinetics and redox reversibility. The electrochemical characterization results further reveal that the optimized SC-NCM811 cathode can well balance the cycle performance and rate capability, showing good electrochemical performance. Overall, microfluidic technology is expected to provide a new strategy for pre-paring single-crystal Ni-rich cathode materials, which may extend to the commercial application of other cathode materials.
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14.
  • Liu, Wei, et al. (författare)
  • Coherent dynamics of multi-spin V-B(-) center in hexagonal boron nitride
  • 2022
  • Ingår i: Nature Communications. - : Nature Portfolio. - 2041-1723. ; 13:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Hexagonal boron nitride (hBN) has recently been demonstrated to contain optically polarized and detected electron spins that can be utilized for implementing qubits and quantum sensors in nanolayered-devices. Understanding the coherent dynamics ofmicrowave driven spins in hBN is of crucial importance for advancing these emerging new technologies. Here, we demonstrate and study the Rabi oscillation and related phenomena of a negatively charged boron vacancy (V-B(-)) spin ensemble in hBN. We report on different dynamics of the V-B(-) spins at weak and strong magnetic fields. In the former case the defect behaves like a single electron spin system, while in the latter case it behaves like a multi-spin system exhibiting multiple-frequency dynamical oscillation as beat in the Ramsey fringes. We also carry out theoretical simulations for the spin dynamics of V-B(-) and reveal that the nuclear spins can be driven via the strong electron nuclear coupling existing in V-B(-) center, which can be modulated by the magnetic field and microwave field.
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15.
  • Mahdavi, Ardeshir, et al. (författare)
  • Necessary conditions for multi-domain indoor environmental quality standards
  • 2020
  • Ingår i: Sustainability. - : MDPI AG. - 2071-1050. ; 12:20, s. 1-24
  • Tidskriftsartikel (refereegranskat)abstract
    • A discussion of sustainability in architecture cannot be meaningfully carried out without the inclusion of most buildings’ central purpose, namely the provision of indoor environments that are accommodating of occupants’ needs and requirements. To this end, building designers and operators are expected to demonstrate compliance with codes and standards pertaining to indoor environmental quality (IEQ). However, the majority of conventional IEQ standards, codes, and guidelines have a single-domain character, in that they address IEQ in terms of a number of isolated domains (i.e., thermal, visual, acoustic, air quality). In this context, the present contribution explores the current state of multi-domain IEQ evaluation approaches and the necessary conditions for their further development and application. Toward this end, a number of common building rating schemes were selected and analyzed in detail. The results of this assessment imply the necessity of both short-term improvements of the existing schemes in terms of the transparency and plausibility of the applied point allocation and weighting strategies and the fundamental need for a deeper empirically grounded understanding of the nature of occupants’ perception of and behavior in the built environments.
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16.
  • Rawal, Rajan, et al. (författare)
  • Personal comfort systems: A review on comfort, energy, and economics
  • 2020
  • Ingår i: Energy and Buildings. - : Elsevier BV. - 0378-7788. ; 214
  • Forskningsöversikt (refereegranskat)abstract
    • Conventional heating, ventilation, and air-conditioning (HVAC) systems are designed to condition the entire building volume. In contrast, Personal Comfort Systems (PCS) target conditioning only the occupied zones of the space, while maintaining the remaining volume at a relatively under-conditioned state. PCS offer the occupants the choice of modulating their immediate thermal ambience with local controls. The individual-level control helps in improving the subjective thermal and air quality acceptability with the desired thermal sensation. This review paper details on the various types of heating, cooling, ventilation, heating with ventilation, and cooling with ventilation PCS devices. It summarises the thermal ambience created by the respective PCS devices and the resultant subjective responses of the occupants. This review also identifies the energy saving potential of various kinds of PCS devices, the power use of PCS devices, and discusses their economic viability.
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17.
  • Schweiker, Marcel, et al. (författare)
  • Evaluating assumptions of scales for subjective assessment of thermal environments – Do laypersons perceive them the way, we researchers believe?
  • 2020
  • Ingår i: Energy and Buildings. - : Elsevier BV. - 0378-7788. ; 211
  • Tidskriftsartikel (refereegranskat)abstract
    • People's subjective response to any thermal environment is commonly investigated by using rating scales describing the degree of thermal sensation, comfort, and acceptability. Subsequent analyses of results collected in this way rely on the assumption that specific distances between verbal anchors placed on the scale exist and that relationships between verbal anchors from different dimensions that are assessed (e.g. thermal sensation and comfort) do not change. Another inherent assumption is that such scales are independent of the context in which they are used (climate zone, season, etc.). Despite their use worldwide, there is indication that contextual differences influence the way the scales are perceived and therefore question the reliability of the scales’ interpretation. To address this issue, a large international collaborative questionnaire study was conducted in 26 countries, using 21 different languages, which led to a dataset of 8225 questionnaires. Results, analysed by means of robust statistical techniques, revealed that only a subset of the responses are in accordance with the mentioned assumptions. Significant differences appeared between groups of participants in their perception of the scales, both in relation to distances of the anchors and relationships between scales. It was also found that respondents’ interpretations of scales changed with contextual factors, such as climate, season, and language. These findings highlight the need to carefully consider context-dependent factors in interpreting and reporting results from thermal comfort studies or post-occupancy evaluations, as well as to revisit the use of rating scales and the analysis methods used in thermal comfort studies to improve their reliability.
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18.
  • Sullivan, Patrick F., et al. (författare)
  • Leveraging base-pair mammalian constraint to understand genetic variation and human disease
  • 2023
  • Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 380:6643, s. 367-
  • Tidskriftsartikel (refereegranskat)abstract
    • Thousands of genomic regions have been associated with heritable human diseases, but attempts to elucidate biological mechanisms are impeded by an inability to discern which genomic positions are functionally important. Evolutionary constraint is a powerful predictor of function, agnostic to cell type or disease mechanism. Single-base phyloP scores from 240 mammals identified 3.3% of the human genome as significantly constrained and likely functional. We compared phyloP scores to genome annotation, association studies, copy-number variation, clinical genetics findings, and cancer data. Constrained positions are enriched for variants that explain common disease heritability more than other functional annotations. Our results improve variant annotation but also highlight that the regulatory landscape of the human genome still needs to be further explored and linked to disease.
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19.
  • Weis, Erik, 1992- (författare)
  • Iridium-Catalyzed C−H Activation Methods for Late-Stage Functionalization of Pharmaceuticals
  • 2022
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • C-H activations have over the recent decades risen from a mere curiosity to a viable synthetic strategy. However, challenges in terms of accessible transformations, selectivity and functional group tolerance limit the widespread applicability of this approach. The aim of the work presented in this thesis was to develop directed ortho C-H activation methodologies specifically designed for applications in drug discovery. The [Cp*Ir(III)] catalytic system was key for the herein described transformations.Chapter 2 covers the development of selective monoiodination of benzoic acids. A mono/di selectivity >20:1 was observed throughout a range of diversely functionalized substrates. Mechanistic investigations revealed the key role of the Ag(I) additive in controlling selectivity.Chapter 3 discusses C-H methylations applied to a wide range of benzoic acids, including examples of late-stage functionalization of marketed drugs. The methodology also allows for introduction of CD3 groups. Biological studies demonstrated positive effect on biological and physical properties of pharmaceuticals as the result of methylation.In chapter 4 the C-H amination and sulfonamidation of benzoic acids is described, with applications for the synthesis of aminated analogues of drug-like molecules. Rapid synthesis of conjugates relevant to drug discovery is also demonstrated.Chapter 5 is dedicated to the development of a general C-H amination protocol, successfully applied to 21 distinct directing groups. The utility of the method is demonstrated by the functionalization of 11 complex drugs and natural products. Directing group informer libraries and functional group tolerance studies enabled the generation of guidelines for reaction outcome prediction.
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