| 1. |
- Fox, Jackie, et al.
(författare)
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A systematic review and narrative synthesis of occupational therapy-led interventions for individuals with anxiety and stress-related disorders
- 2019
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Ingår i: Occupational Therapy in Mental Health. - Philadelphia, PA : Routledge. - 0164-212X .- 1541-3101. ; 35:2, s. 179-204
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Tidskriftsartikel (refereegranskat)abstract
- Anxiety and stress-related disorders are highly prevalent and impede participation in life activities. Occupational therapists work extensively with people diagnosed with these disorders but the effectiveness of their interventions is unclear. A systematic search strategy identified 19 papers describing 13 studies. Studies varied in methodology, intervention type, and theory base. The results show the potential for lifestyle approaches, occupational science-based programs, and skill-building to improve mental health. The variety of interventions and methodologies of many studies means that the effectiveness of occupational therapy interventions for this population is not yet determined. High-quality research is required to replicate interventions with emerging potential for effectiveness.
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| 2. |
- Lozano, Rodrigo
(författare)
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Analysis of the importance of sustainability drivers and barriers to change in Higher Education Institutions
- 2018
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Although several drivers for and barriers to sustainability have been recognised in Higher Education Institutions, there has been limited research on analysing which are considered to be the most important. Two survey were sent to analyse this. The first survey was answered by nineteen respondents, whilst the second by eleven. The survey responses were analysed using descriptive statistics, rankings in order of importance, and comparison between types of drivers and barriers. This paper provides depth to the drivers for and barriers to sustainability in HEIs’ discussion by: 1) providing the importance of each driver and barrier; 3) offering a ranking of the drivers and barriers; 4) and analysing the relations between drivers and barriers to categorise them.
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| 3. |
- Newton, Sarah, 1981, et al.
(författare)
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Impurity transport and bulk ion flow in a mixed collisionality stellarator plasma
- 2017
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Ingår i: Journal of Plasma Physics. - : Cambridge University Press (CUP). - 0022-3778 .- 1469-7807. ; 83:5
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Tidskriftsartikel (refereegranskat)abstract
- The accumulation of impurities in the core of magnetically confined plasmas, resulting from standard collisional transport mechanisms, is a known threat to their performance as fusion energy sources. Whilst the axisymmetric tokamak systems have been shown to benefit from the effect of temperature screening, that is an outward flux of impurities driven by the temperature gradient, impurity accumulation in stellarators was thought to be inevitable, driven robustly by the inward pointing electric field characteristic of hot fusion plasmas. We have shown in Helander et al. (Phys. Rev. Lett, vol. 118, 2017a, 155002) that such screening can in principle also appear in stellarators, in the experimentally relevant mixed collisionality regime, where a highly collisional impurity species is present in a low collisionality bulk plasma. Details of the analytic calculation are presented here, along with the effect of the impurity on the bulk ion flow, which will ultimately affect the bulk contribution to the bootstrap current.
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| 4. |
- Van Duijnhoven, J., et al.
(författare)
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Systematic review on the interaction between office light conditions and occupational health : Elucidating gaps and methodological issues
- 2019
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Ingår i: Indoor + Built Environment. - : Sage Publications. - 1420-326X .- 1423-0070. ; 28:2, s. 152-174
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Forskningsöversikt (refereegranskat)abstract
- Purpose: The International Commission on Illumination (CIE) recommends researchers to investigate a wide variety of behavioural and health outcomes. However, researchers often investigate only a part of occupational health (OH) in relation to light. A literature study (2002–2017) regarding the relationship between office lighting conditions and OH was performed to identify gaps and methodological issues.Method: The OH outcomes investigated in this paper were grouped according to the International Classification of Diseases and analysed per category: physical and physiological health, mental health, eye health, sleep parameters and visual comfort.Results: Findings from the literature study (20 eligible papers) showed that all OH aspects were mostly but not exclusively measured subjectively. Furthermore, most studies investigated only a fraction of office lighting parameters and OH aspects.Conclusions: It seems that Correlated Colour Temperature (CCT) and illuminance mainly correlate with OH. However, this may also be explained by gaps and methodological issues in studies described in eligible papers. Based on the literature study, an overview was composed elucidating gaps and methodological issues of office lighting and OH studies. It can be used to design and target the purpose of light and health research.
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| 5. |
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| 6. |
- Bergin, Philip, 1975, et al.
(författare)
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Gastric gelatinase B/matrix metalloproteinase-9 is rapidly increased in Helicobacter felis-induced gastritis.
- 2008
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Ingår i: FEMS immunology and medical microbiology. - 0928-8244. ; 52:1, s. 88-98
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Tidskriftsartikel (refereegranskat)abstract
- It has previously been shown that matrix metalloproteinase-9 (MMP-9) levels, originating from macrophages, are considerably increased in human Helicobacter pylori-associated gastritis. Here, the early kinetics of the MMP-9 response resulting from Helicobacter infection in C57BL/6 and MMP-9 knock-out mice using the murine Helicobacter felis model were examined. H. felis infection induced severe gastritis in the murine stomach at just 2 weeks after infection. Before gastritis, an increase was observed in MMP-9-positive cells detected by immunohistochemistry in the basal lamina propria. This finding was corroborated by gelatin zymography of stomach samples. As the gastritis increased so did the concentration of MMP-9 and the incidence of gastric MMP-9-positive cells, their location corresponding to that of macrophages. In contrast, systemic levels of MMP-9 remained unchanged. When MMP-9-deficient mice were infected with H. felis, no significant difference in gastritis development was detected compared with disease development in wild-type animals. We conclude that MMP-9 production is an early event in the response to gastric Helicobacter infection, a feature that may favor the recruitment of immune cells early during infection. At later stages, however, the increased levels of MMP-9 may damage the integrity of the stomach mucosa.
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| 7. |
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| 8. |
- Verma, Gaurav, et al.
(författare)
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RNA and metabolic disorders
- 2020
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Ingår i: RNA-Based Regulation in Human Health and Disease. - 9780128171936 ; , s. 175-199
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Bokkapitel (refereegranskat)abstract
- Obesity is reaching levels never seen before in the world population, causing a rise in the incidence of metabolic disorders. The increase of visceral storage of adipose tissue is related to chronic inflammation and deregulation of the metabolism, causing insulin resistance, dyslipidemia and endothelial dysfunction. These pathologies, when they appear together, are known as metabolic syndrome and are associated with an increased risk of atherosclerotic cardiovascular disease, and type 2 Diabetes Mellitus. Recent studies have demonstrated a close link between maternal nutrition and chronic metabolic disease, suggesting epigenetic mechanisms that could affect the way we face this problem in the future. In such context, is of great importance to fully understand the mechanisms that control expression of the genes involved. In this work we will focus on the role of RNA as a key regulatory element in the control of gene expression in metabolic disorders.
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| 9. |
- Azad, A. K., et al.
(författare)
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Structural, magnetic and electrochemical characterization of La(0.83)A(0.17)Fe(0.5)Cr(0.5)O(3-delta) (A = Ba, Ca) perovskites
- 2009
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Ingår i: Materials Research Bulletin. - : Elsevier BV. - 0025-5408. ; 44:7, s. 1451-1457
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Tidskriftsartikel (refereegranskat)abstract
- The structural, magnetic and electrical properties of the perovskite-type compound La(0.83)A(0.17)Fe(0.5)Cr(0.5)O(3-delta) (A = Ba, Ca) have been investigated by neutron diffraction, magnetization measurements and conductivity measurements. Rietveld refinement of X-ray and neutron diffraction data shows that the compound adopts an orthorhombic crystal structure with Pbnm symmetry with a random positioning of the iron and chromium cations on the B sublattice. The magnetic structures at 10 K are collinear antiferromagnetic with the magnetic moment per site being equal to 2.91(2)mu(B) (for Ba) and 3.05(2)mu(B) (for Ca). Magnetization measurements confirm the overall antiferromagnetic behavior. The magnetic structure is based Oil a unit cell related to that of the nuclear structure and the magnetic cell can be considered the same as nuclear cell. Barium doped samples show lower oxygen deficiency and higher conductivity than calcium doped samples. At low oxygen pressure, both compounds show p-type electronic conduction. (c) 2009 Elsevier Ltd. All rights reserved.
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| 10. |
- Bonardi, A., et al.
(författare)
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Study of the LOFAR radio self-trigger and single-station acquisition mode
- 2018
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Ingår i: 35th International Cosmic Ray Conference, ICRC 2017, 10-20 July 2017. - : Sissa Medialab Srl.
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Konferensbidrag (refereegranskat)abstract
- The LOw Frequency ARay (LOFAR) observatory is a multipurpose radio antenna array aimed to detect radio signals in the frequency range 10-240 MHz. Radio antennas are clustered into over 50 stations, and are spread along Central and Northern Europe. The LOFAR core, where the density of stations is highest, is instrumented with the LOfar Radboud air shower Array (LORA), covering an area of about 300 m diameter centered at the LOFAR core position. Since 2011 the LOFAR core has been used for detecting radio-signals associated to cosmic-ray air showers in the energy range 1016 - 1018 eV. Data acquisition is triggered by the LORA scintillator array, which provides energy, arrival direction, and core position estimates of the detected air shower too. Thus only the core of the LOFAR array is currently used for cosmic-ray detection. In order to extend the energy range of the detected cosmic rays, it is necessary to expand the effective collecting area to the whole LOFAR array. On this purpose, a detailed study about the LOFAR potentialities of working in self-trigger mode, i.e. with the cosmic-ray data acquisition trigger provided by the radio-antenna only, is presented here. A new method based on the intensity and the frequency spectrum for determining the air shower position to be implemented on LOFAR remote stations is presented too. © Copyright owned by the author(s) under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives 4.0 International License (CC BY-NC-ND 4.0).
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| 11. |
- Dettwiler, Paul, 1961
(författare)
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Facilities Management of the Offices of Growth Firms: Phases and Location
- 2006
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- What relations can be found between the concepts of "growth firms" and "facilities management"? As firms grow and expand their facilities together with the facilities related services, they must in some way fulfil the increased and changing needs during the development of the growth firms. Managing the facilities implies a multitude of related activities, which require skills that have to be developed internally or are acquired externally. The studies aim to investigate two research questions: the first is: How do growth firms handle the facilities management of their offices in successive phases of their evolution? A theoretical approach links facilities management to theories of growth firms. A major part of this thesis concentrates both conceptually and empirically to a lifecycle model that has its focus on the development of facilities management for growth firms. The three-phase model is formulated and consists of an entrepreneurial, a managerial, and a consolidation phase for growth firms. This growth phase model was used as a tool for analysis of both qualitative and quantitative studies. The qualitative study focuses on spatial expansion of six growth firms in the Gothenburg region that is then followed by a survey that covers the whole of Sweden with a 40% response rate from 967 growth firms. Among the findings it is revealed that firms that decide to enter a curriculum of FM development also have the lowest age in fulfilling general growth criteria, i.e. firms that grow faster also apply more FM than other firms. Those firms are represented by all major business sectors. In the final part of the covering paper the initial lifecycle model of FM is adjusted to a new concept according to the findings of the research project and the phases are given new characteristic names, i.e. factotum, struture, and balance. The facilities are related in some way to the surrounding world, whereby location issues are also involved in the pursued studies. Internal and external factors influence that development of FM in firms, the second research question is thus: What patterns can be found between facilities management of offices of growth firms and their location? In this thesis, location issues and FM are related in various foci: (1) single site locations are compared to multisite locations, (2) location alternatives, i.e. city cores, suburbs, rural area and company parks and (3) relocation. A model is created based on facilities management issues related to location and business cycles.
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| 12. |
- Diener, Silvia, et al.
(författare)
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Mineral transformations in steel slag used as landfill cover liner material
- 2007
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Ingår i: SARDINIA 2007. - Cagliari : CISA, Environmental Sanitary Engineering Centre. - 9788862650038
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Konferensbidrag (refereegranskat)abstract
- In Europe, 15.2 million tonnes of steel slags have been generated in 2004 (Euroslag, 2006) out if which almost 6 million tonnes came from electric arc furnace (EAF) steelmaking and secondary metallurgical processes. In the presented project from Luleå University of Technology, two types of EAF slag and one slag originating from secondary metallurgical processes named ladle slag are investigated. The chemical and physical properties of these slags have been studied in detail (Herrmann, 2006; Andreas et al., 2005). For utilising steel slags in the liner of a landfill cover the long-term stability of the minerals is of great importance. Therefore, the ageing of steel slag minerals is evaluated with the help of a laboratory experiment. Particularly, the research questions, the experimental set-up and the methodology are presented. The present paper is part of a research project of the Division of Waste Science and Technology at Luleå University of Technology, Sweden in cooperation with Uddeholm Tooling AB, Hagfors municipality and MiMeR (Mineral and Metal Recycling Research Centre). It is investigated if steel slags are stable as a landfill cover liner material. The long-term stability is evaluated by determining the factors influencing the mineralogy of the slags and possible mineral transformations through ageing under the environmental conditions in a liner. The experiment includes two similar types of EAF slag and one ladle slag. Each steel slag sample is made by mixing 50% EAF slag and 50% ladle slag, addition of water and compaction. The specimens are stored in boxes under different atmospheric conditions. A reduced multivariate design has been chosen to determine the impact of different factors on the slag mineralogy. The factors that are varied in the experiment are relative humidity, carbon dioxide and temperature of the atmosphere surrounding the slag material as well as ageing time and the quality of the water used for sample making (see table 1). Table 1. Factorial design for ageing experiment of steel slagsLowMiddleHighRelative humidity30% -100%Carbon dioxide content0.036 (air)20 % * 100 %Temperature5 °C30 °C60 °CTime 1 month6 months1 yearWater quality destilled water -LeachateThe ageing of minerals is expected to initiate mineral transformations in steel slags. Primary phases will alter into secondary mineral phases. Changes in mineralogy can influence the stability of the liner. To evaluate mineralogy and properties of the aged steel slag, different analyses will be performed after the storage time of the specimens. X-ray diffraction and scanning electron microscopy as well as shear strength, acid neutralisation capacity and cation exchange capacity will be included. A possible mineral transformation for an alkaline material as steel slags can be the reaction of calcium ions from calcium silicates with the carbon dioxide resulting in the precipitation of calcium carbonate. Through this carbonation reaction, the transport of carbon dioxide into the bulk of the specimen could be hindered by the reaction products. Therefore, surface morphology can influence mineral transformations. First results and evaluations will be presented at the conference. REFERENCES Andreas L., Herrmann I., Lidstrom-Larsson M. & Lagerkvist A. (2005) Physical properties of steel slag to be reused in a landfill cover, Sardinia 2005, Tenth International Waste Management and Landfill Symposium, S. Margherita di Pula, Cagliari, Italy; 3 - 7 October 2005Euroslag (2006) Legal status of Slags. Position Paper. January 2006. The European Slag Association - EUROSLAG. Duisburg, Germany.Herrmann I. (2006). Use of Secondary Construction Material in Landfill Cover Liners. Licentiate Thesis. Luleå University of Technology, Sweden.
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| 13. |
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| 14. |
- Khamespanah, Ehsan, et al.
(författare)
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State Distribution Policy for Distributed Model Checking of Actor Models
- 2015
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Ingår i: Electronic Communications of the EASST. - Berlin : Universitätsverlag der TU Berlin. - 1863-2122. ; 72, s. 1-15
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Tidskriftsartikel (refereegranskat)abstract
- Model checking temporal properties is often reduced to finding accepting cycles in Büchi automata. A key ingredient for an effective distributed model checking technique is a distribution policy that does not split the potential accepting cycles of the corresponding automaton among several nodes. In this paper, we introduce a distribution policy to reduce the number of split cycles. This policy is based on the call dependency graph, obtained from the message passing skeleton of the model. We prove theoretical results about the correspondence between the cycles of call dependency graph and the cycles of the concrete state space and provide empirical data obtained from applying our distribution policy in state space generation and reachability analysis. We take Rebeca, an imperative interpretation of actors, as our modeling language and implement the introduced policy in its distributed state space generator. Our technique can be applied to other message-driven actor-based models where concurrent objects or services are units of concurrency.
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| 15. |
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| 16. |
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| 17. |
- Marsk, A, et al.
(författare)
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If nuchal translucency screening is combined with first-trimester serum screening the need for fetal karyotyping decreases
- 2006
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Ingår i: Acta Obstetricia et Gynecologica Scandinavica. - : Wiley. - 1600-0412 .- 0001-6349. ; 85:5, s. 534-538
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Tidskriftsartikel (refereegranskat)abstract
- Background. This case-control study was performed to evaluate whether adding first-trimester maternal serum testing to nuchal translucency measurement would improve the antenatal detection of Down's syndrome and decrease the number of women offered fetal karyotyping. Methods. In the Swedish Nuchal Translucency Trial 39,572 pregnant women were randomized to a routine scan at 12-14 gestational weeks including nuchal translucency screening for Down's syndrome, or a routine scan at 16-18 gestational weeks. From the early scan group 47 pregnancies with Down's syndrome were identified and for each case three controls were chosen. Of 189 women asked to participate, 31 cases and 108 controls with a singleton pregnancy and frozen sample from 8-14 gestational weeks available for analysis accepted participation. Maternal sera were analyzed for free beta human chorionic gonadotrophin and pregnancy-associated plasma protein A. The risk for Down's syndrome was calculated using combinations of maternal age, crown-rump length, nuchal translucency, and biochemistry. A risk >= 1/250 was considered increased and an indication for fetal karyotyping. Results. Risk calculated on the basis of maternal age alone would have identified 21 of the 31 Down's syndrome cases by karyotyping 61 of the 139 fetuses. Maternal age and nuchal translucency would have identified 29 cases by karyotyping 51 fetuses. Maternal age, nuchal translucency, and biochemistry would also have identified 29 cases by karyotyping 37 fetuses. Conclusions. By adding first trimester biochemistry to nuchal translucency measurement the detection rate of fetuses with Down's syndrome seems to remain unchanged whereas the antenatal risk group to be offered fetal karyotyping decreases.
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