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- Mårdh, Selina
(författare)
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Weak central coherence in patients with Alzheimer’s disease
- 2013
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Ingår i: Neural Regeneration Research. - 1673-5374 .- 1876-7958. ; 8:8, s. 760-766
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Tidskriftsartikel (refereegranskat)abstract
- Central coherence refers to the ability to interpret details of information into a whole. To date, the concept of central coherence is mainly used in research of autism, Asperger’s syndrome and recently in the research on eating disorders. The main purpose of the present study was to examine central coherence in patients with Alzheimer’s disease. Nine Alzheimer’s disease patients and ten age- and gender-matched control subjects, who differed significantly in neurological assessment, were shown a picture of a fire. Compared to control subjects, the Alzheimer’s disease patients described the picture in a fragmented way by mentioning details and separate objects without perceiving the context of the fire. In conclusion, patients with Alzheimer’s disease are at the weak end of central coherence, and hence suffer from a fragmented view of their surroundings. The findings have important clinical implications for the understanding of patients with Alzheimer’s diseaseand also for the possibility of caregivers to meet the Alzheimer’s disease individual in an appropriate way in the everyday care.
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- Martins, Ana, et al.
(författare)
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Changes in social emotion recognition following traumatic frontal lobe injury
- 2012
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Ingår i: Neural Regeneration Research. - 1673-5374 .- 1876-7958. ; 7:2, s. 101-108
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Tidskriftsartikel (refereegranskat)abstract
- Changes in social and emotional behaviour have been consistently observed in patients withtraumatic brain injury. These changes are associated with emotion recognition deficits whichrepresent one of the major barriers to a successful familiar and social reintegration. In the presentstudy, 32 patients with traumatic brain injury, involving the frontal lobe, and 41 age- andeducation-matched healthy controls were analyzed. A Go/No-Go task was designed, where eachparticipant had to recognize faces representing three social emotions (arrogance, guilt andjealousy). Results suggested that ability to recognize two social emotions (arrogance and jealousy)was significantly reduced in patients with traumatic brain injury, indicating frontal lesion can reduceemotion recognition ability. In addition, the analysis of the results for hemispheric lesion location(right, left or bilateral) suggested the bilateral lesion sub-group showed a lower accuracy on allsocial emotions.
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