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Endoscopic third ve...
Endoscopic third ventriculostomy for adults with hydrocephalus: creating a prognostic model for success: protocol for a retrospective multicentre study (Nordic ETV)
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- Tefre, Sondre (author)
- Rigshosp, Denmark
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- Lilja-Cyron, Alexander (author)
- Rigshosp, Denmark
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- Arvidsson, Lisa (author)
- Karolinska Institutet,Karolinska Univ Hosp, Sweden
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- Bartek, Jiri (author)
- Karolinska Institutet,Karolinska Univ Hosp, Sweden
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- Corell, Alba (author)
- Sahlgrens Univ Hosp, Sweden
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- Forsse, Axel (author)
- Odense Univ Hosp, Denmark
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- Glud, Andreas Norgaard (author)
- Aarhus Univ Hosp, Denmark
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- Abu Hamdeh, Sami (author)
- Uppsala Univ Hosp, Sweden
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- Hansen, Frederik Lundgaard (author)
- Aarhus Univ Hosp, Denmark
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- Huotarinen, Antti (author)
- Kuopio Univ Hosp, Finland
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- Johansson, Conny (author)
- Univ Hosp Umea, Sweden
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- Kamarainen, Olli-Pekka (author)
- Kuopio Univ Hosp, Finland
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- Korhonen, Tommi (author)
- Oulu Univ Hosp, Finland; Univ Oulu, Finland
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- Kotkansalo, Anna (author)
- Turku Univ Hosp, Finland; Turku Univ Hosp, Finland
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- Mansoor, Nadia Mauland (author)
- St Olavs Hosp Univ Sykehuset & Trondheim, Norway
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- Mireles, Eduardo Erasmo Mendoza (author)
- Univ Oslo, Norway; Rikshosp Univ Hosp, Norway
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- Miscov, Rares (author)
- Aalborg Univ Hosp, Denmark
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- Munthe, Sune (author)
- Odense Univ Hosp, Denmark
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- Nittby-Redebrandt, Henrietta (author)
- Lund Univ Hosp, Sweden
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- Obad, Nina (author)
- Haukeland Hosp, Norway
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- Pedersen, Lars Kjelsberg (author)
- Univ Hosp North Norway, Norway
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- Posti, Jussi (author)
- Turku Univ Hosp, Finland; Turku Univ Hosp, Finland
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- Raj, Rahul (author)
- Helsinki Univ Hosp, Finland; Univ Helsinki, Finland
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- Satopaa, Jarno (author)
- Helsinki Univ Hosp, Finland; Univ Helsinki, Finland
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- Stahl, Nils (author)
- Lund Univ Hosp, Sweden
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- Tetri, Sami (author)
- Oulu Univ Hosp, Finland; Univ Oulu, Finland
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- Tobieson, Lovisa (author)
- Linköpings universitet,Avdelningen för neurobiologi,Medicinska fakulteten,Region Östergötland, Neurokirurgiska kliniken US
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- Juhler, Marianne (author)
- Rigshosp, Denmark
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(creator_code:org_t)
- 2022-01-31
- 2022
- English.
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In: BMJ Open. - : BMJ PUBLISHING GROUP. - 2044-6055. ; 12:1
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
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- Introduction Endoscopic third ventriculostomy (ETV) is becoming an increasingly widespread treatment for hydrocephalus, but research is primarily based on paediatric populations. In 2009, Kulkarni et al created the ETV Success score to predict the outcome of ETV in children. The purpose of this study is to create a prognostic model to predict the success of ETV for adult patients with hydrocephalus. The ability to predict who will benefit from an ETV will allow better primary patient selection both for EN and shunting. This would reduce additional second procedures due to primary treatment failure. A success score specific for adults could also be used as a communication tool to provide better information and guidance to patients. Methods and analysis The study will adhere to the Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis reporting guidelines and conducted as a retrospective chart review of all patients >= 18 years of age treated with EN at the participating centres between 1 January 2010 and 31 December 2018. Data collection is conducted locally in a standardised database. Univariate analysis will be used to identify several strong predictors to be included in a multivariate logistic regression model. The model will be validated using K-fold cross validation. Discrimination will be assessed using area under the receiver operating characteristic curve (AUROC) and calibration with calibration belt plots. Ethics and dissemination The study is approved by appropriate ethics or patient safety boards in all participating countries.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Samhällsfarmaci och klinisk farmaci (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Social and Clinical Pharmacy (hsv//eng)
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- ref (subject category)
- art (subject category)
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BMJ Open
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- By the author/editor
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Tefre, Sondre
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Lilja-Cyron, Ale ...
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Arvidsson, Lisa
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Bartek, Jiri
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Corell, Alba
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Forsse, Axel
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Glud, Andreas No ...
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Abu Hamdeh, Sami
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Hansen, Frederik ...
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Huotarinen, Antt ...
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Johansson, Conny
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Kamarainen, Olli ...
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Korhonen, Tommi
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Kotkansalo, Anna
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Mansoor, Nadia M ...
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Mireles, Eduardo ...
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Miscov, Rares
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Munthe, Sune
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Nittby-Redebrand ...
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Obad, Nina
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Pedersen, Lars K ...
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Posti, Jussi
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Raj, Rahul
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Satopaa, Jarno
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Stahl, Nils
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Tetri, Sami
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Tobieson, Lovisa
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Juhler, Marianne
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Social and Clini ...
- Articles in the publication
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BMJ Open
- By the university
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Linköping University
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Karolinska Institutet