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Sökning: WFRF:(Gudmundsson Saemundur) > (2015-2017)

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1.
  • Dahlbäck, Charlotte, et al. (författare)
  • Alterations in ductus venosus velocity indices in relation to umbilical venous pulsations and perinatal outcome.
  • 2015
  • Ingår i: Acta Obstetricia et Gynecologica Scandinavica. - : Wiley. - 1600-0412 .- 0001-6349.
  • Tidskriftsartikel (refereegranskat)abstract
    • Abnormal blood velocity in the ductus venosus is more frequently detected than pulsations in the umbilical vein, but both are considered indicators of fetal compromise. The aim of this study was to investigate blood flow patterns in the ductus venosus and the association between individual blood velocity ratios and pulsations in the umbilical vein and perinatal outcome.
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2.
  • Dahlbäck, Charlotte, et al. (författare)
  • Increased pulsatility in the fetal ductus venosus is not related to altered cardiac strain in high-risk pregnancies.
  • 2016
  • Ingår i: Journal of Maternal-Fetal & Neonatal Medicine. - : Informa UK Limited. - 1476-7058 .- 1476-4954. ; 29:8, s. 1328-1333
  • Tidskriftsartikel (refereegranskat)abstract
    • Blood flow velocity patterns in fetal veins are considered to reflect cardiac function, but have not been convincingly documented. The aim of this study was to generate reference values for fetal cardiac strain and compare it with results in fetuses with signs of increased venous pulsatility.
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3.
  • Dahlbäck, Charlotte, et al. (författare)
  • Investigations on atrial function in fetuses with signs of impaired placental function.
  • 2015
  • Ingår i: Prenatal Diagnosis. - : Wiley. - 1097-0223 .- 0197-3851. ; 35:6, s. 605-611
  • Tidskriftsartikel (refereegranskat)abstract
    • Cardiac dysfunction has been shown in cases of placental insufficiency, but few reports exist on fetal atrial function. The aim of this study was to generate reference values for atrial strain and compare them to results in fetuses with signs of increased placental resistance and abnormal venous circulation.
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4.
  • Gudmundsson, Saemundur, et al. (författare)
  • Placental pulsatility index : a new, more sensitive parameter for predicting adverse outcome in pregnancies suspected of fetal growth restriction
  • 2017
  • Ingår i: Acta Obstetricia et Gynecologica Scandinavica. - : Wiley. - 0001-6349 .- 1600-0412. ; 96:2, s. 216-222
  • Tidskriftsartikel (refereegranskat)abstract
    • Introduction: The pulsatility indices of the umbilical and uterine arteries are used as the surrogate measures of utero-placental perfusion. Combining the two might simplify the evaluation of total placental vascular impedance, possibly improve prediction of adverse outcomes, and help identify pregnancies with suspected fetal growth restriction that need more intense surveillance. Material and methods: Umbilical and uterine blood flow velocities were recorded using pulsed-wave Doppler in a longitudinal study of 53 low-risk pregnancies (248 observations) during 20–40 weeks of gestation. Pulsatility indices was calculated for each of these vessels. A new placental pulsatility index was constructed as: (umbilical artery pulsatility index + mean of the left and right uterine artery pulsatility indices)/2, and mean +2 SD defined as abnormal. Gestational age-specific reference percentiles were calculated for the second half of pregnancy and related to values obtained from 340 pregnancies with suspected intra-uterine growth restriction to test its ability to predict adverse pregnancy outcome. Results: The placental pulsatility index was closely associated with gestational age and decreased with advancing gestation in normal pregnancy. The placental pulsatility index had a higher sensitivity and comparable specificity in predicting adverse outcome in pregnancies suspected of intra-uterine fetal growth restriction when compared with conventional umbilical and uterine artery pulsatility indices. Conclusions: The new placental pulsatility index, reflecting placental vascular impedance on both the fetal and maternal side of placenta, improves prediction of adverse outcome in pregnancies suspected of intra-uterine fetal growth restriction.
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