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- Neely, K E, et al.
(författare)
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Activation domain-mediated targeting of the SWI/SNF complex to promoters stimulates transcription from nucleosome arrays
- 1999
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Ingår i: Molecular Cell. - 1097-2765 .- 1097-4164. ; 4:4, s. 649-655
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Tidskriftsartikel (refereegranskat)abstract
- The yeast SWI/SNF complex is required for the transcription of several yeast genes and has been shown to alter nucleosome structure in an ATP-dependent reaction. In this study, we show that the complex stimulated in vitro transcription from nucleosome templates in an activation domain-dependent manner. Transcription stimulation by SWI/SNF required an activation domain with which it directly interacts. The acidic activation domains of VP16, Gcn4, Swi5, and Hap4 interacted directly with the purified SWI/SNF complex and with the SWI/SNF complex in whole-cell extracts. The similarity of activation domain interactions and transcriptional stimulation between SWI/SNF and the SAGA histone acetyltransferase complex may account for their apparent overlapping functions in vivo.
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2. |
- Sohler, D, et al.
(författare)
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Spectroscopy of neutron deficient Ge-65
- 1997
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Ingår i: Zeitschrift für Physik A Hadrons and Nuclei. - : Springer Science and Business Media LLC. - 0939-7922 .- 1431-5831. ; 357:3, s. 239-240
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Tidskriftsartikel (refereegranskat)abstract
- Excited states of 65Ge were populated via the 12C + 58Ni (261 MeV) reaction using the NORDBALL detector array equipped with charged-particle and neutron detector systems for reaction channel separation. On the basis of γγ-coincidence relations and angular distribution ratios a significantly extended level scheme was constructed up to E x = 9 MeV and J π = (33/2−). The low-energy states of the nucleus are discussed in the framework of the interacting boson-fermion model.
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