| 1. |
- Akimov, D., et al.
(författare)
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Physics with WASA and PROMICE
- 1994
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Ingår i: Physics with GeV-particle beams, Juelich 1994. ; , s. 519-530
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Konferensbidrag (refereegranskat)
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| 2. |
- Pascher, R, et al.
(författare)
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Computer-assisted 3D analysis of cell distributions in the normal and epileptic cerebral cortex: description of a methodology in progress.
- 1993
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Ingår i: Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. - 0895-6111. ; 17:4-5, s. 405-10
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Tidskriftsartikel (refereegranskat)abstract
- This paper describes software routines that (a) visualizes a stack of several thousands of aligned sequential photographic two-dimensional (2D) images stored in an image processing system; (b) creates a data base containing information about objects identified sequentially from the 2D images; (c) transfers the data base to a graphical terminal; (d) reconstructs a three-dimensional (3D) object space; and (e) supports on-line interaction between the image processing system and the graphical terminal. As an application example, the cell content of a prism of motor cerebral cortex of the cat is reconstructed. Preliminary results from reconstructing human epileptic temporal cortex (cortical microdysgenesia) are also reported.
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| 3. |
- Skoglund, Thomas, 1969, et al.
(författare)
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3D reconstruction of biological objects from sequential image planes--applied on cerebral cortex from cat.
- 1993
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Ingår i: Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. - 0895-6111. ; 17:3, s. 165-74
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Tidskriftsartikel (refereegranskat)abstract
- A prism of cat cerebral cortex was reconstructed with a method for three-dimensional (3D) representation of biological objects. A series of 918 semithin sections were digitized into an image analysis system. The images were aligned and analyzed, and a data base with the coordinates and a classification of the cells was created. The data base (i.e., the cortical prism) was visualized in a 3D graphic terminal, and parameters such as columnar and lamellar organization, clustering, and cell density were analyzed. A neuronal perikaryon and its neurites was reconstructed and shown together with the cortical prism.
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| 4. |
- Jönson, C, et al.
(författare)
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Effects of hypovolemia on blood flow, arterial [HCO3-], and HCO3- output in the rat duodenum.
- 1990
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Ingår i: American Journal of Physiology. - 0002-9513 .- 2163-5773. ; 259:2 Pt 1, s. G179-83
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Tidskriftsartikel (refereegranskat)abstract
- The effects of bleeding-induced hypovolemia on duodenal blood flow (microsphere technique), arterial [HCO3-], and duodenal HCO3- secretion (in situ titration) were investigated in chloralose-anesthetized rats. A 10% decrease in blood volume reduced duodenal HCO3- secretion by 44%, duodenal blood flow by 31%, and arterial [HCO3-] by 11%. In a group with cervically cut vagal nerves, basal duodenal HCO3- secretion was greater than 50% lower compared with controls. Basal blood flow and arterial [HCO3-] were on similar levels as in nonvagotomized animals. Furthermore, bleeding failed to lower duodenal alkaline output in rats with cut vagal nerves, although blood flow and arterial [HCO3-] were reduced to a similar extent as in the vagally intact controls. In a yohimbine-treated group, a 10% bleeding reduced duodenal blood flow by 28% and arterial [HCO3-] by 7% without influencing duodenal HCO3- secretion. We suggest that the hypovolemia-induced inhibition of duodenal alkaline secretion is not caused by a decrease in blood and/or arterial [HCO3-]. Instead, other factors may be of importance, for example, neural effects on enteric secretomotor neurons or directly on the secreting epithelium.
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| 5. |
- Ledin, T., et al.
(författare)
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Dynamic posturography in psychoorganic syndrome
- 1991
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Ingår i: Vertigo, nausea, tinnitus and hypoacusia due to head and neck trauma. - Amsterdam : Excerpta Medica. - 0444811508 ; , s. 367-369
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Konferensbidrag (refereegranskat)
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| 6. |
- Steenfos, H, et al.
(författare)
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Increased gene expression of scatter factor-hepatocyte growth factor and basic fibroblast growth factor in granulation tissue in the rat.
- 1993
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Ingår i: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. - 1067-1927. ; 1:4, s. 231-5
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Tidskriftsartikel (refereegranskat)abstract
- Scatter factor-hepatocyte growth factor is a protein secreted by fibroblasts which disperses colonies of epithelial cells and keratinocytes in culture. The factor is also a patent mitogen for hepatocytes, synthesized in the liver. Basic fibroblast growth factor, another heparin-binding factor, is most abundant in the brain but also plays a role in wound healing. Using a solution hybridization/RNAase protection assay, we have measured the abundance of messenger RNA for scatter factor-hepatocyte growth factor and basic fibroblast growth factor in granulation tissue obtained from subcutaneously Hunt-Schilling wound cylinders. The levels of scatter factor-hepatocyte growth factor messenger RNA increased after weeks 2 through 4 to a twofold higher level in weeks 5 through 7 after implantation of the cylinders, whereas no changes in basic fibroblast growth factor messenger RNA levels were noticed. At week 3 after implantation of the cylinders, scatter factor-hepatocyte growth factor messenger RNA levels in granulation tissue were more than threefold higher than in skin dermis fibroblasts but markedly lower than in the liver. The abundance of basic fibroblast growth factor messenger RNA was also significantly increased in granulation tissue compared with dermis but, as expected, markedly lower than in the brain. In conclusion, the gene expression of the scatter factor-hepatocyte growth factor, as well as basic fibroblast growth factor, is increased in granulation tissue. Because there was a time-dependent increase in the expression of scatter factor-hepatocyte growth factor, it is hypothesized that scatter factor-hepatocyte growth factor acts as a signal from fully developed granulation tissue to stimulate skin epithelial cells to scatter over the wound.
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