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| 2. |
- Andersson-Engels, S., et al.
(författare)
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Tissue diagnostics using laser-induced fluorescence
- 1989
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Ingår i: Berichte der Bunsengesellschaft für Physikalische Chemie. - : Wiley. - 0005-9021. ; 93:3, s. 335-342
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Tidskriftsartikel (refereegranskat)abstract
- We have performed extensive investigations of laser-induced fluorescence in animal and human tissue aimed at instant tissue characterization. Autofluorescence, as well as specific fluorescence from HPD/DHE and other photosensitizers, has been utilized. The studies have been focused on the demarcation of malignant tumours and atheroscleortic plaques. A nitrogen laser or an excimer-pumped dye laser was used to induce fluorescence, which was analysed with an intensified optical multichannel system. A fibre-optic sensor system was developed for the clinical work. Multi-colour fluorescence imaging has also been demonstrated along a line and equipment for two-dimensional imaging is being constructed. Dimensionless spectroscopic functions, which are not affected by factors that are clinically uncontrollable have been employed for optimum tissue discrimination. The investigations have so far been performed in a time-integrated mode, but time-resolved studies are now being initiated to fully exploit the diagnostic power of tissue laser-induced fluorescence. In addition to a presentation of our own work a brief review of tissue fluorescence studies performed by other groups is also given.
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| 3. |
- Herlitz, Johan, et al.
(författare)
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Mortality and morbidity during a five-year follow-up of diabetics with myocardial infarction
- 1988
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Ingår i: Journal of Internal Medicine. - : Wiley-Blackwell Publishing Ltd.. - 0954-6820 .- 1365-2796. ; 224:1, s. 31-38
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Tidskriftsartikel (refereegranskat)abstract
- In 787 patients with acute myocardial infarction originally participating in the Göteborg Metoprolol Trial, mortality and morbidity during 5 years' follow-up were assessed and related to whether patients had diabetes mellitus. Diabetes occurred in 78 patients (10%). Patients with diabetes had a different risk factor pattern, including higher age, higher occurrence of angina pectoris and hypertension, whereas smoking habits did not differ. In the early phase (hospitalization), patients with diabetes had a higher mortality (12% versus 8%), required more treatment for heart failure and stayed longer in hospital. Other morbidity aspects, such as severity of pain, occurrence of severe supraventricular and ventricular arrhythmias, high-degree AV-block and infarct size did not differ. During 5 years' follow-up mortality rate in patients with diabetes mellitus was 55% as compared with 30% among patients with no diabetes (P<0.001). Reinfarction rate during 5 years was 42% in daibetics versus 25% in non-diabetics (P<0.001). In a multivariate analysis, taking into account the differences in risk factor pattern, diabetes turned out to be an independent determinant for long-term mortality and reinfarction (P<0.001). We conclude that patients with diabetes mellitus, developing acute myocardial infarction, is a group with particularly high risk of death and reinfarction. Interventions aiming at its reduction have priority.
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| 12. |
- Cornell, L., et al.
(författare)
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Arbetets sociala former
- 1983
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Ingår i: Historisk tidsskrift nr 4/83.
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Tidskriftsartikel (refereegranskat)
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| 13. |
- Herlitz, Johan, et al.
(författare)
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Effect of media campaign on delay times and ambulance use in suspected acut myocardial infarction
- 1989
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Ingår i: American Journal of Cardiology. - : Excerpta Medica, Inc.. - 0002-9149 .- 1879-1913. ; 64:1, s. 90-93
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Tidskriftsartikel (refereegranskat)abstract
- The early phase in suspected acute myocardial infarction (AMI) is particularly critical. More than 50% of deaths from coronary artery disease occur outside the hospital mainly due to ventricular fibrillation.1 Recent experiences strongly indicate that early intervention with thrombolysis2–4 and β blockers5,6 can limit myocardial damage and thereby improve prognosis. Delay times in suspected AMI have remained stable over the years. Therefore, a media campaign was started in the urban area of Göteborg, Sweden, with the intention to shorten delay times and to increase ambulance use in patients with suspected AMI.
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| 16. |
- Jönsson, L., et al.
(författare)
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Trametes versicolor ligninase: isozyme sequence homology and substrate specificity
- 1989
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Ingår i: FEBS Letters. - 0014-5793 .- 1873-3468. ; 247:1, s. 143-146
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Tidskriftsartikel (refereegranskat)abstract
- The substrate specificity of three ligninase isozymes from the white-rot fungus Trametes versicolor has been investigated using stereochemically defined synthetic dimeric models for lignin. The isozymes have been found to attack non-phenolic β-O-4 as well as β-1 lignin model compounds. This finding confirms the classification of the isozymes from T. versicolor as ligninases. The amino-terminal residues of the three isozymes from T. versicolor have been determined using Edman degradation. Minor differences found between the sequences suggest the existence of several structural genes for ligninase in T. versicolor. Comparisons have been made with the sequences of three previously reported ligninases from Phanerochaete chrysosporium, another lignin-degrading fungus. One of the sequences from P. chrysosporium is distinctly more similar to the T. versicolor isozymes than to the other two sequences from P. chrysosporium.
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| 17. |
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| 18. |
- Karlsson, L
(författare)
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Produktionen av sågade trävaror i Sverige 1976, 1978 och 1983
- 1988
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Materialet omfattar 20--25 sågverk med en årsproduktion av minst 25.000 m3 per sågverk. Svaren utgör 14 % av populationen. Produktionen som ingår är 2,1 milj m3, d v s 18 % av totalproduktionen. Ur statistisk synpunkt är materialet litet, men det torde ändå ge en uppfattning om produktionsförhållandena. Detaljerad statistik per region, marknadsinriktning samt upgifter om de deltagande verken lämnas.
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| 19. |
- Karlsson, Lennart, et al.
(författare)
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Residual stresses and deformations in a welded thin-walled pipe
- 1989
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Ingår i: Weld residual stresses and plastic deformation. - New York : American Society of Mechanical Engineers. - 0791803295
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Konferensbidrag (refereegranskat)abstract
- Deformations and stresses during butt-welding of a pipe are calculated as well as the residual deformations and stresses. The temperature field during welding is calculated using an analytical solution. The deformations and stresses are calculated by use of the finite element method. A thermo-elastoplastic material model is used. Special attention is paid to the influence of the volume changes due to phase transformations on the deformations (radial shrinkage) and the residual stresses. The calculated radial shrinkage and residual stresses are compared to experimental values. Good agreement was obtained.
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| 20. |
- Landin-Olsson, M., et al.
(författare)
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Islet cell and other organ-specific autoantibodies in all children developing Type 1 (insulin-dependent) diabetes mellitus in Sweden during one year and in matched control children
- 1989
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Ingår i: Diabetologia. - 0012-186X. ; 32:6, s. 387-395
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Tidskriftsartikel (refereegranskat)abstract
- The majority (about 90%) of children developing Type 1 (insulin-dependent) diabetes mellitus do not have a first-degree relative with the disease. Nearly all (389/405, 96%) children (0-14 years) in Sweden, who developed diabetes during one year, were therefore studied to compare islet cell, thyroid peroxidase, thyroglobulin, and gastric H+, K+-ATPase antibodies with 321 age, sex, and geographically matched, but non-related, control children. Islet cell (cytoplasmic) antibodies were found in 81% (316/389) of the patients and in 3% (9/321) of the control children (p<0.001). The median islet cell antibody levels were 70 (range 3-8200) Juvenile Diabetes Foundation (JDF) Units in the islet cell antibody positive patients, and 27 (range 17-1200) JDF Units in the control children (NS). Autoantibodies against thyroid peroxidase (8%), thyroglobulin (6%), and gastric H+, K+- ATPase (3%) were all increased in the patients compared with the control children, being 2% (p<0.001), 2% (p<0.01), and 0.3% (p<0.01), respectively. During an observation time of 20-34 months, two of the nine islet cell antibody positive control children developed Type 1 diabetes, after 8 and 25 months respectively, while the others remained healthy and became islet cell antibody negative. None of the islet cell antibody negative control children developed diabetes during the same time of observation. This first investigation of an unselected population of diabetic children and matched control children shows: that islet cell antibodies are strongly associated with newly diagnosed childhood diabetes, that other autoantibodies are more frequent among diabetic children than control children, and that the frequency of islet cell antibodies in the background population of children is higher than previously documented, and could also be transient, underlining that factors additional to islet cell antibodies are necessary for the later development of Type 1 diabetes.
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| 21. |
- Larsson, L, et al.
(författare)
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The measurement of cell growth in coal slurries
- 1989
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Ingår i: Biotechnology Techniques. - 0951-208X. ; 3:5, s. 295-298
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Tidskriftsartikel (refereegranskat)abstract
- Microbial growth in coal slurries can be detected if surfactant is present in the samples by analysing the protein concentration after disintegration of the cells. Without surfactant present in the samples, the proteins are readily adsorbed on the coal surfaces. A suitable surfactant is sodium dodecyl sulphate at 0.5 to 1% of the sample volume
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| 22. |
- Lundberg, Bengt, et al.
(författare)
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Influence of geometrical design on the efficiency of a simple down-the-hole percussive drill
- 1986
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Ingår i: International Journal of Rock Mechanics and Mining Sciences & Geomechanics Abstracts. - : Elsevier BV. - 0148-9062 .- 1879-2073. ; 23:3, s. 281-287
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Tidskriftsartikel (refereegranskat)abstract
- In the present investigation, the simulation program DTH-SIM is used to determine the efficiency of a simple down-the-hole percussive drill, which has the main features of a practical design. The efficiency is obtained as a function of the same dimensionless parameters as in a preceding study of two additional parameters which represent the characteristic impedance and the length of the head of the bit. Several results obtained here for non-uniform bits differ considerably from those established previously for uniform bits
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| 23. |
- Messeter, L, et al.
(författare)
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Immunochemical characterization of a monoclonal anti-Leb blood grouping reagent
- 1984
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Ingår i: Vox Sanguinis. - 1423-0410. ; 46:2, s. 66-74
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Tidskriftsartikel (refereegranskat)abstract
- A haemagglutinating monoclonal anti-LebL antibody has been obtained from a mouse-mouse hybridoma after immunization with the Leb-active oligosaccharide lacto-N-difucohexaose I, coupled to edestin. Of 13 other antibodies obtained, one was able to agglutinate enzyme-treated erythrocytes of all ABO groups and three more were considered to be anti-LebH haemagglutinins. The remaining nine antibodies did not agglutinate red cells. The specificity of the stronger of the anti-LebL haemagglutinins was examined by studying its binding to a number of glycoconjugates and oligosaccharides.
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| 24. |
- Olsson, G, et al.
(författare)
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Microorganisms for Desulfurization of Coal: the Influence of Leaching Compounds on their Growth
- 1989
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Ingår i: Fuel. - 1873-7153. ; 68:10, s. 1270-1274
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Tidskriftsartikel (refereegranskat)abstract
- An investigation was undertaken to outline how microorganisms suggested for use in coal desulphurization are affected by compounds leached from coal. Three species of the genus Sulfolobus were studied. Sulfolobus acidocaldarius was seen to be affected by compounds leached from coal more negatively than Sulfolobus brierleyi and Sulfolobus solfataricus. It was observed that certain conditions during leaching, such as pH, temperature and leaching time, were important for the concentration of compounds leached from coal. It was seen that compounds leached from coal, in some cases, can improve the growth yield for the microorganisms.
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| 25. |
- OLSSON, G, et al.
(författare)
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Mikrobiell Avsvavling av Kol
- 1988
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Ingår i: KEMISK TIDSKRIFT. - 0039-6605. ; 100:5, s. 54-56
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Tidskriftsartikel (populärvet., debatt m.m.)
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