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| 2. |
- Kim, Y J, et al.
(författare)
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A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II.
- 1994
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Ingår i: Cell. - 0092-8674 .- 1097-4172. ; 77:4, s. 599-608
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Tidskriftsartikel (refereegranskat)abstract
- A mediator was isolated from yeast that enabled a response to the activator proteins GAL4-VP16 and GCN4 in a transcription system reconstituted with essentially homogeneous basal factors and RNA polymerase II. The mediator comprised some 20 polypeptides, including the three subunits of TFIIF and other polypeptides cross-reactive with antisera against GAL11, SUG1, SRB2, SRB4, SRB5, and SRB6 proteins. Mediator not only enabled activated transcription but also conferred 8-fold greater activity in basal transcription and 12-fold greater efficiency of phosphorylation of RNA polymerase II by the TFIIH-associated C-terminal repeat domain (CTD) kinase, indicative of mediator-CTD interaction. A holoenzyme form of RNA polymerase II was independently isolated that supported a response to activator proteins with purified basal factors. The holoenzyme proved to consist of mediator associated with core 12-subunit RNA polymerase II.
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| 3. |
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| 4. |
- Li, W.B., et al.
(författare)
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Mechanisms of indentation creep
- 1991
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Ingår i: Acta Metallurgica et Materialia. - 0956-7151. ; 39:12, s. 3099-3110
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Tidskriftsartikel (refereegranskat)abstract
- A physically-based theoretical model is developed for describing the phenomenon of indentation creep over the whole temperature range, from 300 K to melting. In agreement with experimental data collected, the model predicts that most materials, including ceramics, exhibit indentation creep at temperatures down to 300 K. It is established that the principal mechanism causing indentation creep is dislocation glide plasticity. The dominance of this mechanism over the whole temperature range is due to the very high stresses involved in indentation creep. If, however, the grain size is small (typically less than 0.3-0.4 μm) indentation creep may be dominated by grain boundary (Coble) diffusive creep instead. The implications of these results in terms of the design, forming and application of the so-called "hard materials" is discussed.
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| 5. |
- Li, Zheng, et al.
(författare)
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Minimum Variance Prediction for Linear Time-Varying Systems
- 1994
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Ingår i: IFAC Proceedings Volumes. ; 27:8
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Konferensbidrag (refereegranskat)abstract
- In this paper we study the problem of minimum variance prediction for linear time-varying systems. We consider the standard time-varying autoregression moving average (ARMA) model and develop a predictor which guarantees minimum variance prediction for a large class of linear time-varying systems. The predictor is developed based on a pseudocommutation technique for dealing with noncommutativity of linear time-varying operators in a transfer operator framework. We also show connections between this input-output predictor and the Kalman predictor via an example.
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