| 1. |
- Huang, H, et al.
(author)
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Flow cytometric analysis of BHRF1 expression prohibiting apoptosis induced by radiation
- 1999
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In: The Annals of otology, rhinology, and laryngology. - : SAGE Publications. - 0003-4894 .- 1943-572X. ; 108:5, s. 481-484
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Journal article (peer-reviewed)abstract
- The Epstein-Barr virus gene BHRF1 has homology with proto-oncogene bcl-2, which can protect cells from apoptosis. In order to investigate the effect of BHRF1 expression on the anti-apoptotic ability of nasopharyngeal carcinoma (NPC) cells after irradiation, a high—BHRF1 expression vector was constructed and transfected into the NPC cell line CNE2. Then, the alteration of proliferation and apoptosis in the cells was tested by flow cytometry after cobalt 60 irradiation. The results showed that BHRF1 expression could increase G1 delay and decrease the cell percentage in S phase before irradiation, and reduce the apoptotic rate of CNE2 cells and increase the cell percentage in S phase after irradiation. The results suggest that BHRF1 expression is able to alter the cell cycle and protect CNE2 cells from apoptosis induced by radiation.
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| 2. |
- Li, J, et al.
(author)
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An efficient algorithm for two-dimensional frequency estimation
- 1996
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In: MULTIDIMENSIONAL SYSTEMS AND SIGNAL PROCESSING. - : KLUWER ACADEMIC PUBL. - 0923-6082. ; 7:2, s. 151-178
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Journal article (other academic/artistic)abstract
- This paper presents a computationally efficient eigenstructure-based 2D-MODE algorithm for two-dimensional frequency estimation. We derive the theoretical performance of the 2D-MODE estimator and show that it is asymptotically statistically efficient unde
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| 3. |
- Li, J, et al.
(author)
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Angle and waveform estimation via RELAX
- 1997
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In: IEEE TRANSACTIONS ON AEROSPACE AND ELECTRONIC SYSTEMS. - : IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. ; 33:3
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Other publication (other academic/artistic)abstract
- Described here is how the RELAX algorithm, recently proposed for temporal spectral analysis, can be extended to the spatial problem of angle and waveform estimation for both narrowband and wideband plane waves arriving at a uniform linear array (ULA). Bot
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| 4. |
- Li, JA, et al.
(author)
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Efficient direction and polarization estimation with a COLD array
- 1996
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In: IEEE TRANSACTIONS ON ANTENNAS AND PROPAGATION. - : IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. - 0018-926X. ; 44:4, s. 539-547
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Journal article (other academic/artistic)abstract
- This paper considers angle and polarization estimation by means of a cocentered orthogonal loop and dipole (COLD) array, We show that by using the COLD array, the performance of both angle and polarization estimation can be greatly improved, as compared t
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| 5. |
- Li, JA, et al.
(author)
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One-dimensional MODE algorithm for two-dimensional frequency estimation
- 1997
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In: MULTIDIMENSIONAL SYSTEMS AND SIGNAL PROCESSING. - : KLUWER ACADEMIC PUBL. - 0923-6082. ; 8:4, s. 449-468
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Journal article (other academic/artistic)abstract
- In this paper, we describe how the computationally efficient one-dimensional MODE (ID-MODE) algorithm can be used to estimate the frequencies of two-dimensional complex sinusoids. We show that the ID-MODE algorithm is computationally more efficient than t
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| 6. |
- LI, L, et al.
(author)
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Impairment of synaptic vesicle clustering and of synaptic transmission, and increased seizure propensity, in synapsin I-deficient mice
- 1995
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In: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424. ; 92:20, s. 9235-9239
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Journal article (peer-reviewed)abstract
- Synapsin I has been proposed to be involved in the modulation of neurotransmitter release by controlling the availability of synaptic vesicles for exocytosis. To further understand the role of synapsin I in the function of adult nerve terminals, we studied synapsin I-deficient mice generated by homologous recombination. The organization of synaptic vesicles at presynaptic terminals of synapsin I-deficient mice was markedly altered: densely packed vesicles were only present in a narrow rim at active zones, whereas the majority of vesicles were dispersed throughout the terminal area. This was in contrast to the organized vesicle clusters present in terminals of wild-type animals. Release of glutamate from nerve endings, induced by K+,4-aminopyridine, or a Ca2+ ionophore, was markedly decreased in synapsin I mutant mice. The recovery of synaptic transmission after depletion of neurotransmitter by high-frequency stimulation was greatly delayed. Finally, synapsin I-deficient mice exhibited a strikingly increased response to electrical stimulation, as measured by electrographic and behavioral seizures. These results provide strong support for the hypothesis that synapsin I plays a key role in the regulation of nerve terminal function in mature synapses.
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| 7. |
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| 8. |
- Ma, Li-Zheng, 1960
(author)
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Theoretical and Experimental Investigations of Nonlinear Flame Instability
- 1998
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Doctoral thesis (other academic/artistic)abstract
- Flame instability is both important and difficult to understand. Mechanisms of instability are complex, because instability often involves an interaction between several different physical phenomena, such as an unsteady chemical reaction, unsteady flame propagation generating an unsteady flow, acoustic waves or shock waves. So, it is difficult to control these instabilities in combustion systems. Research on combustion instability will promote understanding and provide some rational approaches to the anticipation, prevention, remedy and utilization of unstable combustion. The investigations in this thesis focus on some nonlinear effects of fundamental importance to combustion theory, flame propagation and stretch effects, shock-induced flame-front instability and tulip flame instability by using experimental and theoretical tools. The main goals of this thesis are to study the intrinsic characteristics of flame instability, to describe the mechanisms of instability, and to derive some asymptotic formulations to quantitatively predict the processes of unstable flame development and it final stage. In order to study this process, a level set technique accounting for heat release effects and flame propagation is adopted together with N.S and Euler equations to track the evolution of the flame front in nonlinear hydrodynamic and shock-induced flame instability for 2D and 3D cases. The Schlieren technique is used for experimental visualization of the processes of tulip flame formation. It was found that tulip flame formation and shock-induced flame-front instability are due to the vorticity generated by the misalignment of density and pressure gradients in the systems. The initial inversion of the flame-front is due to the Richtmyer-Meshkov instability. Results also show that the flame propagation speed of a perturbed flame is asymptotically equal to Up=(1+0.293*sqrt(d-1))*sl, where d is the density ratio and sl is the laminar burning speed and the asymptotic amplitude of the flame is approximately A=0.37*L*sqrt(d-1), where L is the flame wave-length. The burning velocity has a minor effect on the asymptotic shape of the flames. When the turbulence scale is much smaller than the size of the combustion apparatus the results can be directly applied to turbulent flames by replacing sl with the turbulent burning velocity.
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