| 1. |
- Nelson, James K., et al.
(författare)
-
Mapping interference resolution across task domains : A shared control process in left inferior frontal gyrus
- 2009
-
Ingår i: Brain Research. - Netherlands : Elsevier Science. - 0006-8993 .- 1872-6240. ; 1256, s. 92-100
-
Tidskriftsartikel (refereegranskat)abstract
- Work in functional neuroimaging has mapped interference resolution processing onto left inferior frontal regions for both verbal working memory and a variety of semantic processing tasks. The proximity of the identified regions from these different tasks suggests the existence of a common, domain-general interference resolution mechanism. The current research specifically tests this idea in a within-subject design using fMRI to assess the activation associated with variable selection requirements in a semantic retrieval task (verb generation) and a verbal working memory task with a trial-specific proactive interference manipulation (recent-probes). High interference trials on both tasks were associated with activity in the midventrolateral region of the left inferior frontal gyrus, and the regions activated in each task strongly overlapped. The results indicate that an elemental component of executive control associated with interference resolution during retrieval from working memory and from semantic memory can be mapped to a common portion of the left inferior frontal gyrus.
|
|
| 2. |
|
|
| 3. |
- Persson, Jonas, et al.
(författare)
-
Cognition and Aging : Typical Development
- 2008
-
Ingår i: Handbook of Developmental Cognitive Neuroscience. - : The MIT Press, Cambridge, US, and London, UK.. - 9780262141048 ; , s. 591-606
-
Bokkapitel (refereegranskat)abstract
- Declining cognitive functions are a normal and inevitable part of healthy aging. Some changes may stem from global alterations in brain functions, including metabolic changes; others may result from localized decline of specific neural circuits. Current research on cognitive aging aims not only to identify the mechanisms that underlie cognitive change, but also to understand and harness the genetic, experiential and environmental factors that promote the preservation of cognitive abilities. Recent technological advances are leading to new breakthroughs in cognitive aging research, while also posing new challenges to understand the relation between genetic, anatomical, physiological, and cognitive factors and to integrate these levels of analysis. Moreover, the availability of high-resolution neuroimaging methods is revising our perspective on aging and giving way to new ideas about the aging mind and brain. We now know that the aging brain is not simply a depleted and reduced version of the younger brain. Instead, recent cognitive neuroscience evidence points to patterns of preservation and decline, along with functional reorganization and plasticity.
|
|
| 4. |
|
|
| 5. |
- Persson, Jonas, et al.
(författare)
-
Gaining Control : Training Executive Function and Far Transfer of the Ability to Resolve Interference [retracted]
- 2008
-
Ingår i: Psychological Science. - : SAGE Publications. - 0956-7976 .- 1467-9280. ; 19:9, s. 881-888
-
Tidskriftsartikel (refereegranskat)abstract
- Functional brain-imaging data document overlapping sites of activation in prefrontal cortex across memory tasks, suggesting that these tasks may share common executive components. We leveraged this evidence to develop a training regimen and a set of transfer tasks to examine the trainability of a putative executive-control process: interference resolution. Eight days of training on high-interference versions of three different working memory tasks increased the efficiency with which proactive interference was resolved on those particular tasks. Moreover, an improved ability to resolve interference was also transferred to different working memory, semantic memory, and episodic memory tasks, a demonstration of far-transfer effects from process-specific training. Participants trained with noninterference versions of the tasks did not exhibit transfer. We infer that the transfer we demonstrated resulted from increased efficiency of the interference-resolution process. Therefore, this aspect of executive control is plastic and adaptive, and can be improved by training.
|
|
