| 1. |
- Abdallah, J, et al.
(författare)
-
Coherent soft particle production in Z decays into three jets
- 2005
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Ingår i: Physics Letters. Section B: Nuclear, Elementary Particle and High-Energy Physics. - : Elsevier BV. - 0370-2693. ; 605:1-2, s. 37-48
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Tidskriftsartikel (refereegranskat)abstract
- Low-energy particle production perpendicular to the event plane in three-jet events produced in Z decays in e(+)e(-) annihilation is measured and compared to that perpendicular to the event axis in two-jet events. The topology dependence of the hadron production ratio is found to agree with a leading-order QCD prediction. This agreement and especially the need for the presence of a destructive interference term gives evidence for the coherent nature of gluon radiation. Hadron production in three-jet events is found to be directly proportional to a single topological scale function of the inter-jet angles. The slope of the dependence of the multiplicity with respect to the topological scale was measured to be 2.211 +/- 0.014(stat.) +/- 0.053(syst.) in good agreement with the expectation given by the colour-factor ratio C-A/C-F = 9/4. This result strongly supports the assumption of local parton-hadron duality, LPHD, at low hadron momentum.
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| 2. |
- Abdallah, J., et al.
(författare)
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Study of double-tagged gamma gamma events at LEPII
- 2006
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Ingår i: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 46:3, s. 559-568
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Tidskriftsartikel (refereegranskat)abstract
- Double-tagged interactions of photons with virtualities Q(2) between 10 GeV2 and 200 GeV2 are studied with the data collected by DELPHI at LEPII from 1998 to 2000, corresponding to an integrated luminosity of 550 pb(-1). The gamma*gamma* -> mu(+)mu(-) data agree with QED predictions. The cross-section of the reaction gamma*gamma* -> hadrons is measured and compared to the LO and NLO BFKL calculations.
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| 3. |
- Abdallah, J., et al.
(författare)
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A determination of the centre-of-mass energy at LEP2 using radiative two-fermion events
- 2006
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Ingår i: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 46:2, s. 295-305
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Tidskriftsartikel (refereegranskat)abstract
- Using e(+)e(-) -> mu(+)mu(-)(gamma) and e(+)e(-) -> q (q) over bar(gamma) events radiative to the Z pole, DELPHI has determined the centre-of-mass energy, root s, using energy and momentum constraint methods. The results are expressed as deviations from the nominal LEP centre-of-mass energy, measured using other techniques. The results are found to be compatible with the LEP Energy Working Group estimates for a combination of the 1997 to 2000 data sets.
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| 4. |
- Abdallah, J., et al.
(författare)
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A measurement of the tau hadronic branching ratios
- 2006
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Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 46:1, s. 1-26
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Tidskriftsartikel (refereegranskat)abstract
- The exclusive and semi-exclusive branching ratios of the tau lepton hadronic decay modes (h(-)upsilon(tau), h(-)pi(0)upsilon(tau), h(-)pi(0)pi(0)upsilon(tau), h(-) >= 2 pi(0)nu(tau), 2h(-)h(+)upsilon(tau), 2h(-)h(+)>= 2 pi(0)upsilon(tau), 3h(-)2h(+)upsilon(tau) and 3h(-)2h(+) >= 1 pi(0)upsilon(tau)) were measured with data from the DELPHI detector at LEP.
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| 5. |
- Abdallah, J., et al.
(författare)
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Determination of the b quark mass at the M-Z scale with the DELPHI detector at LEP
- 2006
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Ingår i: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 46:3, s. 569-583
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Tidskriftsartikel (refereegranskat)abstract
- An experimental study of the normalized three-jet rate of b quark events with respect to light quarks events (light = l equivalent to u, d, s) has been performed using the CAMBRIDGE and DURHAM jet algorithms. The data used were collected by the DELPHI experiment at LEP on the Z peak from 1994 to 2000. The results are found to agree with theoretical predictions treating mass corrections at next-to-leading order. Measurements of the b quark mass have also been performed for both the b pole mass: M-b and the b running mass: m(b)(M-Z). Data are found to be better described when using the running mass. The measurement yields: m(b)(M-Z) = 2.85 +/- 0.18(stat) +/- 0.13(exp) +/- 0.19(had) +/- 0.12(theo) GeV/c(2). for the CAMBRIDGE algorithm. This result is the most precise measurement of the b mass derived from a high energy process. When compared to other b mass determinations by experiments at lower energy scales, this value agrees with the prediction of quantum chromodynamics for the energy evolution of the running mass. The mass measurement is equivalent to a test of the flavour independence of the strong coupling constant with an accuracy of 7 parts per thousand.
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| 6. |
- Abdallah, J., et al.
(författare)
-
Evidence for an excess of soft photons in hadronic decays of Z(0)
- 2006
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Ingår i: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 47:2, s. 273-294
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Tidskriftsartikel (refereegranskat)abstract
- Soft photons inside hadronic jets converted in front of the DELPHI main tracker (TPC) in events of qq disintegrations of the Z(0) were studied in the kinematic range 0.2 < E-y < I GeV and transverse momentum with respect to the closest jet direction P-T < 80 MeV/c. A clear excess of photons in the experimental data as compared to the Monte Carlo predictions is observed. This excess (uncorrected for the photon detection efficiency) is (1.17 +/- 0.06 +/- 0.27) x 10(-3) gamma/jet in the specified kinematic region, while the expected level of the inner hadronic bremsstrahlung (which is not included in the Monte Carlo) is (0.340 +/- 0.001 +/- 0.038) X 10(-3) gamma/jet. The ratio of the excess to the predicted bremsstrahlung rate is then (3.4 +/- 0.2 +/- 0.8), which is similar in strength to the anomalous soft photon signal observed in fixed target experiments with hadronic beams.
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| 7. |
- Abdallah, J., et al.
(författare)
-
Higgs boson searches in CP-conserving and CP-violating MSSM scenarios with the DELPHI detector
- 2008
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Ingår i: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; C:54, s. 1-35
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Tidskriftsartikel (refereegranskat)abstract
- This paper presents the final interpretation of the results from DELPHI on the searches for Higgs bosons in the minimal supersymmetric extension of the Standard Model (MSSM). A few representative scenarios are considered, that include CP conservation and explicit CP violation in the Higgs sector. The experimental results encompass the searches for neutral Higgs bosons at LEP1 and LEP2 in final states as expected in the MSSM, as well as LEP2 searches for charged Higgs bosons and for neutral Higgs bosons decaying into hadrons independent of the quark flavour. The data reveal no significant excess with respect to background expectations. The results are translated into excluded regions of the parameter space in the various scenarios. In the CP-conserving case, these lead to limits on the masses of the lightest scalar and pseudoscalar Higgs bosons, h and A, and on tan beta. The dependence of these limits on the top quark mass is discussed. Allowing for CP violation reduces the experimental sensitivity to Higgs bosons. It is shown that this effect depends strongly on the values of the parameters responsible for CP violation in the Higgs sector.
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| 8. |
- Abdallah, J., et al.
(författare)
-
Investigation of colour reconnection in WW events with the DELPHI detector at LEP-2
- 2007
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Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 51:2, s. 249-269
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Tidskriftsartikel (refereegranskat)abstract
- In the reaction e(+)e(-) -> WW -> (q(1) (q) over bar (2))(q(3)(q) over bar (4)) the usual hadronization models treat the colour singlets q(1)(q) over bar (2) and q(3)(q) over bar (4) coming from two W bosons independently. However, since the. nal state partons may coexist in space and time, cross-talk between the two evolving hadronic systems may be possible during fragmentation through soft gluon exchange. This e. ect is known as colour reconnection. In this article the results of the investigation of colour reconnection e. ects in fully hadronic decays of W pairs in DELPHI at LEP are presented. Two complementary analyses were performed, studying the particle. ow between jets and W mass estimators, with negligible correlation between them, and the results were combined and compared to models. In the framework of the SK-I model, the value for its. parameter most compatible with the data was found to be: (SK)-S-kappa-I = 2.2(-1.3) (+2.5) corresponding to the probability of reconnection P-reco to be in the range 0.31 < P-reco < 0.68 at 68% confidence level with its best value at 0.52.
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| 9. |
- Abdallah, J., et al.
(författare)
-
Masses, lifetimes and production rates of Xi(-) and Xi(+) at LEP 1
- 2006
-
Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 639:3-4, s. 179-191
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Tidskriftsartikel (refereegranskat)abstract
- Measurements of the Xi(-) and (Xi) over bar (+) masses, mass differences, lifetimes and lifetime differences are presented. The (Xi) over bar (+) sample used is much larger than those used previously for such measurements. In addition, the S production rates in Z -> b (b) over bar and Z -> q (q) over bar events are compared and the position xi* of the maximum of the distribution in Z -> q (q) over bar events is measured.
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| 10. |
- Abdallah, J., et al.
(författare)
-
Measurement and interpretation of fermion-pair production at LEP energies above the Z resonance
- 2006
-
Ingår i: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 45:3, s. 589-632
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Tidskriftsartikel (refereegranskat)abstract
- This paper presents DELPHI measurements and interpretations of cross-sections, forward-backward asymmetries, and angular distributions, for the e(+)e(-) -> f (f) over bar process for centre-of-mass energies above the Z resonance, from root s similar to 130-207 GeV at the LEP collider. The measurements are consistent with the predictions of the Standard Model and are used to study a variety of models including the S-Matrix ansatz for e(+)e(-) -> f (f) over bar scattering and several models which include physics beyond the Standard Model: the exchange of Z' bosons, contact interactions between fermions, the exchange of gravitons in large extra dimensions and the exchange of (v) over tilde in R-parity violating supersymmetry.
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| 11. |
- Abdallah, J., et al.
(författare)
-
Search for a fourth generation b '-quark at LEP-II at root s=196-209GeV
- 2007
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Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 50:3, s. 507-518
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Tidskriftsartikel (refereegranskat)abstract
- A search for the pair production of fourth generation b'-quarks was performed using data taken by the DELPHI detector at LEP-II. The analysed data were collected at centre-of-mass energies ranging from 196 to 209 GeV, corresponding to an integrated luminosity of 420 pb(-1). No evidence for a signal was found. Upper limits on BR(b'-> bZ) and BR(b'-> bZ) were obtained for b' masses ranging from 96 to 103 GeV/c(2) stop. These limits, together with the theoretical branching ratios predicted by a sequential four generations model, were used to constrain the value of R-CKM=vertical bar V-cb(') /V-tb'V-tb vertical bar there V-cb', V-tb' and V-tb are elements of the extended CKM matrix.
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| 12. |
- Abdallah, J., et al.
(författare)
-
Search for excited leptons in e(+)e(-) collisions at root s=189-209 GeV
- 2006
-
Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 46:2, s. 277-293
-
Tidskriftsartikel (refereegranskat)abstract
- A search for excited lepton production in e(+)e(-) collisions was performed using the data collected by the DELPHI detector at LEP at centre-of-mass energies ranging from 189 GeV to 209 GeV, corresponding to an integrated luminosity of approximately 600 pb(-1). No evidence for excited lepton production was found. In searches for pair-produced excited leptons, lower mass limits were established in the range 94-103 GeV/c(2), depending on the channel and model assumptions. In searches for singly-produced excited leptons, upper limits on the parameter f/Lambda were established as a function of the mass.
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| 13. |
- Abdallah, J., et al.
(författare)
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Study of triple-gauge-boson couplings ZZZ, ZZ gamma and Z gamma gamma at LEP
- 2007
-
Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 51:3, s. 525-542
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Tidskriftsartikel (refereegranskat)abstract
- Neutral triple-gauge-boson couplings ZZZ, ZZγ and Zγγ have been studied with the DELPHI detector using data at energies between 183 and 208 GeV. Limits are derived on these couplings from an analysis of the reactions e+e-→Zγ, using data from the final states γff̄, with f=q or ν, from e+e-→ZZ, using data from the four-fermion final states qq̄qq̄, qq̄μ+μ-, qq̄e+e-, qq̄νν̄, μ+μ-νν̄ and e+e-νν̄, and from e+e-→Zγ*, in which the final state γ is off mass-shell, using data from the four-fermion final states qq̄e+e- and qq̄μ+μ-. No evidence for the presence of such couplings is observed, in agreement with the predictions of the Standard Model.
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| 14. |
- Abdallah, J., et al.
(författare)
-
A study of b(b)over-bar production in e(+)e(-) collisions at root s=130-207 GeV
- 2009
-
Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 60:1, s. 1-15
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Tidskriftsartikel (refereegranskat)abstract
- Measurements are presented of R-b, the ratio of the b (b) over bar cross-section to the q (q) over bar cross-section in e(+)e(-) collisions, and the forward-backward asymmetry A(FB)(b) at twelve energy points in the range root s = 130-207 GeV. These results are found to be consistent with the Standard Model expectations. The measurements are used to set limits on new physics scenarios involving contact interactions.
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| 15. |
- Abdallah, J, et al.
(författare)
-
Determination of heavy quark non-perturbative parametersfrom spectral moments in semileptonic B decays
- 2006
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Ingår i: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 45:1, s. 35-59
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Tidskriftsartikel (refereegranskat)abstract
- Moments of the hadronic invariant mass and of the lepton energy spectra in semileptonic B decays have been determined with the data recorded by the DELPHI detector at LEP. From measurements of the inclusive b-hadron semileptonic decays, and imposing constraints from other measurements on b- and c-quark masses, the first three moments of the lepton energy distribution and of the hadronic mass distribution, have been used to determine parameters which enter into the extraction of vertical bar V-cb vertical bar from the measurement of the inclusive b-hadron semileptonic decay width. The values obtained in the kinetic scheme are: m(b)(1 GeV) = 4.591 +/- 0.062 +/- 0.039 +/- 0.005 GeV/c(2), m(c)(1 GeV) = 1.170 +/- 0.093 +/- 0.055 +/- 0.005 GeV/c(2), m(pi)(2) (1 GeV) = 0.399 +/- 0.048 +/- 0.034 +/- 0.087 GeV2, (p) over tilde (3)(D) = 0.053 +/- 0.017 +/- 0.011 +/- 0.026 GeV3, and include corrections at order 1/m(b)(3). Using these results, and present measurements of the inclusive semileptonic decay partial width of b-hadrons at LEP, an accurate determination of vertical bar V-cb vertical bar is obtained: vertical bar V-cb vertical bar = 0.0421 x (1 +/- 0.014 (meas center dot) +/- 0.014 (fit) +/- 0.015 (th center dot)).
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| 16. |
- Abdallah, J, et al.
(författare)
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Flavour independent searchesfor hadronically decaying neutral Higgs bosons
- 2005
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Ingår i: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044. ; 44:2, s. 147-159
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Tidskriftsartikel (refereegranskat)abstract
- This paper describes flavour independent searches for hadronically decaying neutral Higgs bosons in the data collected by the DELPHI experiment at LEP, at centre-of-mass energies between 189 and 209 GeV. The collected data-set corresponds to an integrated luminosity of around 610 pb(-1). The e(+)e(-) -> hA and e(+)e(-) -> hZand processes are considered, with direct Higgs boson decays into hadrons. No evidence for Higgs boson production is found, and cross-section limits are set as a function of the Higgs boson masses. No explicit assumptions are made on the underlying physics beyond the Standard Model, allowing interpretation of the data in a large class of models.
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| 17. |
- Abdallah, J., et al.
(författare)
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Search for pentaquarks in the hadronic decays of the Z boson with the DELPHI detector at LEP
- 2007
-
Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 653:2-4, s. 151-160
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Tidskriftsartikel (refereegranskat)abstract
- The quark model does not exclude states composed of more than three quarks, like pentaquark systems. Controversial evidence for such states has been published in the last years, in particular: for a strange pentaquark Theta(1540)(+); for a double-strange state, the Xi(1862)(--), subsequently called Phi(1860)--; and for a charmed state, the Theta(c)(3100)(0). If confirmed, a full pentaquark family might exist; such pentaquark states could be produced in e(+)e(-) annihilations near the Z energy. In this Letter a search for pentaquarks is described using the DELPHI detector at LEP, characterized by powerful particle identification sub-systems crucial in the separation of the signal from the background for these states. At 95% CL, upper limits are set on the production rates N of such particles and their charge-conjugate state per Z decay: N-Theta+ x Br(Theta(+) -> pK(S)(0)) < 5.1 x 10(-4), N Theta++ < 1.6 x 10(-3), N Phi(1860)-- x Br((P(1860)-- -> Xi(-)pi(-)) < 2.9 x 10(-4), N-Theta c(3100)0 x Br(Theta(c)(3100)(0) -> D*(+)p) < 8.8 x 10(-4).
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| 18. |
- Abdallah, J., et al.
(författare)
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Single intermediate vector boson production in e(+)e(-) collisions at root s=183-209 GeV
- 2006
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Ingår i: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 45:2, s. 273-289
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Tidskriftsartikel (refereegranskat)abstract
- The production of single charged and neutral intermediate vector bosons in e(+)e(-) collisions has been studied in the data collected by the DELPHI experiment at LEP at centre-of-mass energies between 183 and 209 GeV, corresponding to an integrated luminosity of about 640 pb(-1). The measured cross-sections for the reactions, determined in limited kinematic regions, are in agreement with the Standard Model predictions.
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| 19. |
- Abdallah, J., et al.
(författare)
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Study of leading hadrons in gluon and quark fragmentation
- 2006
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Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 643:3-4, s. 147-157
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Tidskriftsartikel (refereegranskat)abstract
- The study of quark jets in e(+)e(-) reactions at LEP has demonstrated that the hadronisation process is reproduced well by the Lund string model. However. our understanding of gluon fragmentation is less complete. In this study enriched quark and gluon jet samples of different purities are selected in three-jet events from hadronic decays of the Z collected by the DELPHI experiment in the LEP runs during 1994 and 1995. The leading systems of the two kinds of jets are defined by requiring a rapidity gap and their sum of charges is studied. An excess of leading systems with total charge zero is found for gluon jets in all cases, when compared to Monte Carlo simulations with JETSET (with and without Bose-Einstein correlations included) and ARIADNE. The corresponding leading systems of quark jets do not exhibit such an excess. The influence of the gap size and of the gluon purity on the effect is studied and a concentration of the excess of neutral leading systems at low invariant masses (less than or similar to 2 GeV/c(2)) is observed, indicating that gluon jets might have an additional hitherto undetected fragmentation mode via a two-gluon system. This could be an indication of a possible production of gluonic states as predicted by QCD.
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| 20. |
- Abdallah, J., et al.
(författare)
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Study of multi-muon bundles in cosmic ray showers detected with the DELPHI detector at LEP
- 2007
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Ingår i: Astroparticle physics. - : Elsevier BV. - 0927-6505 .- 1873-2852. ; 28:3, s. 273-286
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Tidskriftsartikel (refereegranskat)abstract
- The DELPHI detector at LEP has been used to measure multi-muon bundles originating from cosmic ray interactions with air. The cosmic events were recorded in "parasitic mode" between individual e(+)e(-) interactions and the total live time of this data taking is equivalent to 1.6 x 10(6) s. The DELPHI apparatus is located about 100 m underground and the 84 metres rock overburden imposes a cutoff of about 52 GeV/c on muon momenta. The data from the large volume Hadron Calorimeter allowed the muon multiplicity of 54,201 events to be reconstructed. The resulting muon multiplicity distribution is compared with the prediction of the Monte Carlo simulation based on CORSIKA/QGSJETOI. The model fails to describe the abundance of high multiplicity events. The impact of QGSJET internal parameters on the results is also studied.
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| 21. |
- Abdallah, J, et al.
(författare)
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Bose-Einstein correlations in W+W- events at LEP2
- 2005
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Ingår i: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044. ; 44:2, s. 161-174
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Tidskriftsartikel (refereegranskat)abstract
- Bose-Einstein correlations (BEC) between final state particles in the reaction e(+)e(-) -> W+ W- -> q(1)(q(2)) over barq(3)(q(4)over bar>) over bar) have been studied. Data corresponding to a total integrated luminosity of 550 pb(-1), recorded by the DELPHI detector at centre-of-mass energies ranging from 189 to 209 GeV, were analysed. An indication for inter-W BEC between like-sign particles has been found at the level of 2.4 standard deviations of the combined statistical and systematic uncertainties.
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| 22. |
- Abdallah, J, et al.
(författare)
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Determination of A(FB)(b) at the Z pole using inclusive charge reconstruction and lifetime tagging
- 2005
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Ingår i: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044. ; 40:1, s. 1-25
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Tidskriftsartikel (refereegranskat)abstract
- A novel high precision method measures the b-quark forward-backward asymmetry at the Z pole on a sample of 3,560,890 hadronic events collected with the DELPHI detector in 1992 to 2000. An enhanced impact parameter tag provides a high purity b sample. For event hemispheres with a reconstructed secondary vertex the charge of the corresponding quark or anti-quark is determined using a neural network which combines in an optimal way the full available charge information from the vertex charge, the jet charge and from identified leptons and hadrons. The probability of correctly identifying b-quarks and anti-quarks is measured on the data themselves comparing the rates of double hemisphere tagged like-sign and unlike-sign events. The b-quark forward-backward asymmetry is determined from the differential asymmetry, taking small corrections due to hemisphere correlations and background contributions into account. The results for different centre-of-mass energies are: A(FB)(b) ( 89.449 GeV) = 0.0637 +/- 0.0143( stat.) +/- 0.0017( syst.), A(FB)(b) ( 91.231 GeV) = 0.0958 +/- 0.0032( stat.) +/- 0.0014( syst.), A(FB)(b) ( 92.990 GeV) = 0.1041 +/- 0.0115( stat.) +/- 0.0024( syst.). Combining these results yields the b-quark pole asymmetry A(FB)(b0) = 0.0972 +/- 0.0030( stat.) +/- 0.0014( syst.).
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| 23. |
- Abdallah, J, et al.
(författare)
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Search for eta(b) in two-photon collisions at LEP II with the DELPHI detector
- 2006
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Ingår i: Physics Letters. Section B: Nuclear, Elementary Particle and High-Energy Physics. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 634:4, s. 340-346
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Tidskriftsartikel (refereegranskat)abstract
- The pseudoscalar meson eta(b) has been searched for in two-photon interactions at LEP II. The data sample corresponds to a total integrated luminosity of 617 pb(-1) at centre-of-mass energies ranging from 161 to 209 GeV. Upper limits at a confidence level of 95% on the product Gamma(gamma gamma) (eta(b)) x BR(eta(b)) are 190, 470 and 660 eV/c(2) for the eta(b) decaying into 4, 6 and 8 charged particles, respectively.
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| 24. |
- Elsik, Christine G., et al.
(författare)
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The Genome Sequence of Taurine Cattle : A Window to Ruminant Biology and Evolution
- 2009
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Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 324:5926, s. 522-528
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Tidskriftsartikel (refereegranskat)abstract
- To understand the biology and evolution of ruminants, the cattle genome was sequenced to about sevenfold coverage. The cattle genome contains a minimum of 22,000 genes, with a core set of 14,345 orthologs shared among seven mammalian species of which 1217 are absent or undetected in noneutherian (marsupial or monotreme) genomes. Cattle-specific evolutionary breakpoint regions in chromosomes have a higher density of segmental duplications, enrichment of repetitive elements, and species-specific variations in genes associated with lactation and immune responsiveness. Genes involved in metabolism are generally highly conserved, although five metabolic genes are deleted or extensively diverged from their human orthologs. The cattle genome sequence thus provides a resource for understanding mammalian evolution and accelerating livestock genetic improvement for milk and meat production.
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| 25. |
- Birney, Ewan, et al.
(författare)
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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
- 2007
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 447:7146, s. 799-816
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Tidskriftsartikel (refereegranskat)abstract
- We report the generation and analysis of functional data from multiple, diverse experiments performed on a targeted 1% of the human genome as part of the pilot phase of the ENCODE Project. These data have been further integrated and augmented by a number of evolutionary and computational analyses. Together, our results advance the collective knowledge about human genome function in several major areas. First, our studies provide convincing evidence that the genome is pervasively transcribed, such that the majority of its bases can be found in primary transcripts, including non-protein-coding transcripts, and those that extensively overlap one another. Second, systematic examination of transcriptional regulation has yielded new understanding about transcription start sites, including their relationship to specific regulatory sequences and features of chromatin accessibility and histone modification. Third, a more sophisticated view of chromatin structure has emerged, including its inter-relationship with DNA replication and transcriptional regulation. Finally, integration of these new sources of information, in particular with respect to mammalian evolution based on inter- and intra-species sequence comparisons, has yielded new mechanistic and evolutionary insights concerning the functional landscape of the human genome. Together, these studies are defining a path for pursuit of a more comprehensive characterization of human genome function.
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