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- Andersson Grönlund, Marita, 1959-, et al.
(författare)
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Acupuncture treatment in patients with keratoconjunctivitis sicca : a pilot study
- 2004
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Ingår i: Acta Ophthalmologica Scandinavica. - : Wiley-Blackwell Publishing Inc.. - 1395-3907 .- 1600-0420. ; 82:3 Pt 1, s. 283-290
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Tidskriftsartikel (refereegranskat)abstract
- AIM: To evaluate the effects of acupuncture in patients with keratoconjunctivitis sicca (KCS).MATERIAL AND METHODS: Twenty-five patients (20 women, five men) with KCS were randomly assigned to an acupuncture treatment group or a control group. The effects of acupuncture were evaluated by a questionnaire on symptoms, visual analogue scale recordings, registration of drop frequency, and dry eye tests. Ten acupuncture sessions were given. Follow-up was carried out after 2-3 weeks and again after a mean period of 8 months.RESULTS: Patients receiving acupuncture felt better at the first follow-up compared with the control group (p = 0.036). However, no statistical significance could be found concerning any change, or difference, in the total number of subjective symptoms, dosage frequency or, as indicated by the dry eye tests, tear quality, tear secretion and ocular surface disease.CONCLUSION: The results indicate that acupuncture has subjective beneficial effects in patients with KCS and could therefore be tried as a complement to ordinary treatment.
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| 3. |
- Grönlund, Marita Andersson, 1959, et al.
(författare)
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Acupuncture treatment of patients with keratoconjunctivitis sicca:a pilot study
- 2004
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Ingår i: Acta Ophthalmologica Scandinavica. - 1395-3907. ; 82, s. 283-290
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Tidskriftsartikel (refereegranskat)abstract
- ABSTRACT. Aim: To evaluate the effects of acupuncture in patients with keratoconjunctivitis sicca (KCS). Material and Methods: Twenty-five patients (20 women, five men)with KCS were randomly assigned to an acupuncture treatment group or a control group. The effects of acupuncture were evaluated by a questionnaire on symptoms, visual analogue scale recordings, registration of drop frequency, and dry eye tests. Ten acupuncture sessions were given. Follow-up was carried out after 2–3weeks and again after a mean period of 8months. Results: Patients receiving acupuncture felt better at the first follow-up compared with the control group (p¼0.036). However, no statistical significance could be found concerning any change, or difference, in the total number of subjective symptoms, dosage frequency or, as indicated by the dry eye tests, tear quality, tear secretion and ocular surface disease. Conclusion: The results indicate that acupuncture has subjective beneficial effects in patients with KCS and could therefore be tried as a complement to ordinary treatment. Key words: acupuncture – dry eye – keratoconjunctivitis sicca (KCS) – sensory nerve stimulation – Sjo¨ gren’s syndrome (SS) Acta Ophthalmol. Scand. 2004: 82: 283–290
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| 4. |
- Hardarson, Thorir, 1967, et al.
(författare)
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Time-lapse recordings of human corneal epithelial healing
- 2004
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Ingår i: Acta Ophthalmologica Scandinavica. - 1395-3907. ; 82, s. 184-8
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Tidskriftsartikel (refereegranskat)abstract
- Time-lapse recordings of human corneal epithelial healing.Hardarson T, Hanson C, Claesson M, Stenevi U. Department of Obstetrics and Gynaecology, Gothenburg University, Gothenburg, Sweden. PURPOSE: The aim of this study was to design an experimental set-up for the study of human corneal epithelial wound healing in a controlled in vitro situation. METHODS: A time-lapse set-up was used. This allowed for pictures to be captured with a magnification ranging from x 80 to x 1800. Pictures were captured at 1-min intervals during the observation period, which lasted up to 4 days. Human corneal tissue was obtained from the Eye Bank or from surgery. A small, rounded lesion was produced in the corneal epithelium with a miniature drill. The specimens were placed in a mini-incubator; the camera focused on the epithelial lesion and continuously observed using the time-lapse set-up. RESULTS: The healing process of human corneal epithelium could be followed for several days. The initial healing response could be divided into a slow, a rapid and a consolidating phase. The first two phases lasted about 12 hours, and by then, epithelial cells covered the lesion. Depending on the origin of the tissue and the placement of the lesion, variations in the healing response could be seen. CONCLUSION: The time-lapse technique makes it possible to study epithelial wound healing over time at the cellular level. Data collected in this way can fill the gap between in vivo studies, where, by nature, human wound healing studies are restricted, and cell culture techniques, where cellular responses in many cases differ from the in vivo situation. PMID: 15043538 [PubMed - indexed for MEDLINE]
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| 8. |
- Lundström, Mats, et al.
(författare)
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Postoperative aphakia in modern cataract surgery - Part 1 : Analysis of incidence and risks based on 5-year data from the Swedish National Cataract Register
- 2004
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Ingår i: Journal of cataract and refractive surgery. - : Ovid Technologies (Wolters Kluwer Health). - 0886-3350 .- 1873-4502. ; 30:10, s. 2105-2110
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: To study the incidence of aphakia after cataract extraction and evaluate the relative risk for this outcome in subgroups of patients based on preoperative conditions. Setting: Sixty-two community-run or private clinics participating in the Swedish National Cataract Register. Methods: Data on cataract extractions were collected prospectively from 1997 through 2001. The set of data also covered type of surgery and type of intraocular lens (IOL), including a "no lens implanted" option. All data were stored in a database. Database calculations were made of frequencies and risk ratios of postoperative aphakia in the subgroups of patients based on preoperative conditions. Results: For the entire study period, postoperative aphakia was reported in 1410 of 287951 surgeries for which complete IOL data were available, corresponding to an overall frequency of 0.49%. The occurrence of ocular comorbidity and poor preoperative visual acuity (≤0.1) in the eye to be operated on was significantly related to postoperative aphakia for each year of the study (P<.001). Glaucoma and poor visual acuity (≤0.1) in the surgical eye meant a 12.8 higher risk for aphakia after surgery than a better visual acuity (>0.1) and no ocular comorbidity. Conclusions: This national 5-year survey showed that in routine cataract surgery performed during the study, 1 of every 200 operations ended in postoperative aphakia. Poor visual acuity (≤0.1) in the eye to be operated on combined with ocular comorbidity was the highest risk factor for postoperative aphakia. © 2004 ASCRS and ESCRS.
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| 9. |
- Lundström, Mats, et al.
(författare)
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Postoperative aphakia in modern cataract surgery - Part 2 : Detailed analysis of the cause of aphakia and the visual outcome
- 2004
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Ingår i: Journal of cataract and refractive surgery. - : Ovid Technologies (Wolters Kluwer Health). - 0886-3350 .- 1873-4502. ; 30:10, s. 2111-2115
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: To study the incidence of aphakia after cataract surgery, the surgical complications that can lead to it, and the visual outcome. Setting: Six community-run eye clinics participating in the Swedish National Cataract Register. Methods: Data on cataract extractions were collected prospectively from 1997 through 2001. The data also covered the type of surgery and type of intraocular lens, including a "no lens implanted" option. All data were stored in a database. These data were supplemented with data on the intended type of surgery, type of complications, possible second surgery, and visual outcome. Results: The overall incidence of postoperative aphakia was 0.65%. In 87.1% of cases, the aphakia was not planned, corresponding to an incidence of 0.48%. Unplanned aphakia was significantly related to poor preoperative vision, old age, and the presence of ocular comorbidity. The most frequent reasons for unplanned aphakia were intraoperative capsule problems and vitreous loss. In two thirds of cases, a second operation was performed. In 41% of all cases, the final visual acuity was 0.5 or better and in 27.7%, worse than 0.1. Conclusions: During the study period, 1 of every 200 routine cataract surgeries ended in unplanned aphakia. The incidence of surgical complications leading to unplanned aphakia and a final visual acuity worse than 0.1 (20/200) was 7.8 per 10000 operations in cases with no ocular comorbidity and 27.6 per 10000 operations in cases with ocular comorbidity. © 2004 ASCRS and ESCRS.
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| 11. |
- Makar, Anna, et al.
(författare)
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Effects of sympathetic denervation on the hyaluronan content of the anterior segment in the normal and traumatized rabbit eye.
- 2002
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Ingår i: Acta Ophthalmologica Scandinavica. - : Wiley. - 1395-3907. ; 80:3, s. 327-331
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Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: To determine whether there is any involvement of sympathetic nerves in the regulation of ocular hyaluronan production in the normal and traumatized rabbit iris. METHODS: Unilateral sympathetic denervation was performed by removing the right superior cervical ganglion. Hyaluronan concentrations in the iris and aqueous were measured with a radiometric assay at various time intervals after denervation. Peripheral iridectomy was also performed in both denervated and non-denervated eyes. RESULTS: Hyaluronan concentrations in the iris tissue after denervation were observed to have increased after 1 day, reaching a peak of 129.6 +/- 5.7 microg/g wet weight at day 3. Two weeks later, hyaluronan concentrations had fallen back to normal levels. Ocular trauma with peripheral iridectomy in denervated eyes caused an increase of hyaluronan content of up to 253.5 +/- 30.5 microg/g wet weight, which was not significantly different from hyaluronan concentrations observed after the same trauma in non-denervated eyes. CONCLUSION: Cervical sympathetic denervation results in a moderate increase of the hyaluronan content in the rabbit iris and does not appear to influence the hyaluronan response of the iris to trauma.
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| 12. |
- Rudolph, Thiemo, et al.
(författare)
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16S rDNA PCR analysis of infectious keratitis: a case series
- 2004
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Ingår i: Acta Ophthalmologica Scandinavica. - 1395-3907. ; 82:4, s. 463-467
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Tidskriftsartikel (refereegranskat)abstract
- ABSTRACT. Purpose: To discuss the value of polymerase chain reaction (PCR) in the management of bacterial infectious keratitis. Methods: Corneal scrapings of four patients with severe infectious keratitis were analysed by culture and PCR of 16S ribosomal DNA (rDNA), followed by direct sequencing of the resulting amplicon. The medical history of the patients included laser-assisted in-situ keratomileusis (LASIK), penetrating keratoplasty (PKP) and trauma. Results: Using PCR we were able to identify a possible pathogen in all four cases, while bacterial cultures were either negative or did not correspond to the clinical picture. The identified bacteria were a Pseudomonas species, Abiotrophia defectiva, Stenotrophomonas maltophilia and Porphyromonas gingivalis. Conclusions: Analysis of corneal scrapings by 16S rDNA PCR should be considered as a supplement to standard microbiological procedures. However, the results of this relatively new method have to be interpreted carefully.
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