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Proteomics Standard...
Proteomics Standards Initiative's ProForma 2.0 : Unifying the Encoding of Proteoforms and Peptidoforms br
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- LeDuc, Richard D. (författare)
- Northwestern Univ, Natl Resource Translat & Dev Prote, Evanston, IL 60611 USA.
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- Deutsch, Eric W. (författare)
- Inst Syst Biol, Seattle, WA 98109 USA.
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- Binz, Pierre-Alain (författare)
- Lausanne Univ Hosp, Clin Chem Serv, CH-1011 Lausanne, Switzerland.
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- Fellers, Ryan T. (författare)
- Northwestern Univ, Natl Resource Translat & Dev Prote, Evanston, IL 60611 USA.
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- Cesnik, Anthony J. (författare)
- KTH,Science for Life Laboratory, SciLifeLab,Cellulär och klinisk proteomik,Stanford Univ, Dept Genet, Stanford, CA 94305 USA.;Chan Zuckerberg Biohub, San Francisco, CA 94158 USA.
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- Klein, Joshua A. (författare)
- Boston Univ, Program Bioinformat, Boston, MA 02215 USA.
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- Van den Bossche, Tim (författare)
- VIB UGent Ctr Med Biotechnol, B-9052 Ghent, Belgium.;Univ Ghent, Fac Med & Hlth Sci, Dept Biomol Med, B-9000 Ghent, Belgium.
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- Gabriels, Ralf (författare)
- VIB UGent Ctr Med Biotechnol, B-9052 Ghent, Belgium.;Univ Ghent, Fac Med & Hlth Sci, Dept Biomol Med, B-9000 Ghent, Belgium.
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- Yalavarthi, Arshika (författare)
- Northwestern Univ, Natl Resource Translat & Dev Prote, Evanston, IL 60611 USA.
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- Perez-Riverol, Yasset (författare)
- EMBL European Bioinformat Inst EMBL EBI, European Mol Biol Lab, Cambridge CB10 1SD, England.
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- Carver, Jeremy (författare)
- UCSD, Ctr Computat Mass Spectrometry, Dept Comp Sci & Engn, La Jolla, CA 92093 USA.;UCSD, Skaggs Sch Pharm & Pharmaceut Sci, La Jolla, CA 92093 USA.
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- Bittremieux, Wout (författare)
- UCSD, Skaggs Sch Pharm & Pharmaceut Sci, La Jolla, CA 92093 USA.;UCSD, Ctr Computat Mass Spectrometry, La Jolla, CA 92093 USA.
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- Kawano, Shin (författare)
- Toyama Univ Int Studies, Toyama, Toyama 9301292, Japan.;Res Org Informat & Syst, Joint Support Ctr Data Sci Res, Database Ctr Life Sci, Kashiwa, Chiba 2770871, Japan.
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- Pullman, Benjamin (författare)
- UCSD, Ctr Computat Mass Spectrometry, La Jolla, CA 92093 USA.;UCSD, Dept Comp Sci & Engn, La Jolla, CA 92093 USA.
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- Bandeira, Nuno (författare)
- UCSD, Ctr Computat Mass Spectrometry, Dept Comp Sci & Engn, La Jolla, CA 92093 USA.;UCSD, Skaggs Sch Pharm & Pharmaceut Sci, La Jolla, CA 92093 USA.
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- Kelleher, Neil L. (författare)
- Northwestern Univ, Natl Resource Translat & Dev Prote, Evanston, IL 60611 USA.
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- Thomas, Paul M. (författare)
- Northwestern Univ, Natl Resource Translat & Dev Prote, Evanston, IL 60611 USA.;AbbVie Inc, 1401 Sheridan Rd, N Chicago, IL 60064 USA.
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- Vizcaino, Juan Antonio (författare)
- EMBL European Bioinformat Inst EMBL EBI, European Mol Biol Lab, Cambridge CB10 1SD, England.
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Northwestern Univ, Natl Resource Translat & Dev Prote, Evanston, IL 60611 USA Inst Syst Biol, Seattle, WA 98109 USA. (creator_code:org_t)
- 2022-03-15
- 2022
- Engelska.
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Ingår i: Journal of Proteome Research. - : American Chemical Society (ACS). - 1535-3893 .- 1535-3907. ; 21:4, s. 1189-1195
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- It is important for the proteomics community to have a standardizedmanner to represent all possible variations of a protein or peptide primary sequence,including natural, chemically induced, and artifactual modifications. The HumanProteome Organization Proteomics Standards Initiative in collaboration with severalmembers of the Consortium for Top-Down Proteomics (CTDP) has developed astandard notation called ProForma 2.0, which is a substantial extension of the originalProForma notation developed by the CTDP. ProForma 2.0 aims to unify therepresentation of proteoforms and peptidoforms. ProForma 2.0 supports use casesneeded for bottom-up and middle-/top-down proteomics approaches and allows theencoding of highly modified proteins and peptides using a human- and machine-readable string. ProForma 2.0 can be used to represent protein modifications in a specified or ambiguous location, designated bymass shifts, chemical formulas, or controlled vocabulary terms, including cross-links (natural and chemical) and atomic isotopes.Notational conventions are based on public controlled vocabularies and ontologies. The most up-to-date full specification documentand information about software implementations are available athttp://psidev.info/proforma.
Ämnesord
- NATURVETENSKAP -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
Nyckelord
- ProForma
- proteoform
- peptidoform
- top-down proteomics
- file formats
- data standards
- mass spectrometry
- FAIR
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LeDuc, Richard D ...
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Deutsch, Eric W.
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Binz, Pierre-Ala ...
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Fellers, Ryan T.
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Cesnik, Anthony ...
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Klein, Joshua A.
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Van den Bossche, ...
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Gabriels, Ralf
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Yalavarthi, Arsh ...
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Perez-Riverol, Y ...
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Carver, Jeremy
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Bittremieux, Wou ...
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Kawano, Shin
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Pullman, Benjami ...
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Bandeira, Nuno
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Kelleher, Neil L ...
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Thomas, Paul M.
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Vizcaino, Juan A ...
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