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Träfflista för sökning "WFRF:(Wilharm A.) srt2:(2019)"

Sökning: WFRF:(Wilharm A.) > (2019)

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1.
  • Cossarizza, A., et al. (författare)
  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)
  • 2019
  • Ingår i: European Journal of Immunology. - : Wiley. - 0014-2980 .- 1521-4141. ; 49:10, s. 1457-1973
  • Tidskriftsartikel (refereegranskat)abstract
    • These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community. They provide the theory and key practical aspects of flow cytometry enabling immunologists to avoid the common errors that often undermine immunological data. Notably, there are comprehensive sections of all major immune cell types with helpful Tables detailing phenotypes in murine and human cells. The latest flow cytometry techniques and applications are also described, featuring examples of the data that can be generated and, importantly, how the data can be analysed. Furthermore, there are sections detailing tips, tricks and pitfalls to avoid, all written and peer-reviewed by leading experts in the field, making this an essential research companion.
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2.
  • 2019
  • Tidskriftsartikel (refereegranskat)
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3.
  • Wilharm, A, et al. (författare)
  • Mutual interplay between IL-17-producing γδT cells and microbiota orchestrates oral mucosal homeostasis
  • 2019
  • Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 1091-6490. ; 116:7, s. 2652-2661
  • Tidskriftsartikel (refereegranskat)abstract
    • Elucidating the mechanisms by which homeostasis is established and maintained in the oral mucosa is important for human health. In this study we investigated the ontogeny and function of gingival γδT cells. The majority of these cells originate from embryonic precursors that maintain themselves locally independent of circulating γδT cells arising from adult precursors. The oral microbiota regulates the development of γδT cells, particularly those of embryonic origin. γδT cells represent the major sources of IL-17–producing cells in the gingiva, and they play a critical role in down-modulating gingival steady-state immunity that subsequently shapes oral microbial diversity. This suggests that oral homeostasis requires mutual interactions between γδT cells and the microbiota.
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  • Resultat 1-3 av 3

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