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| 5. |
- Xiang, F, et al.
(author)
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A Huntington disease-like neurodegenerative disorder maps to chromosome 20p.
- 1998
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In: American Journal of Human Genetics. - : Elsevier BV. - 0002-9297 .- 1537-6605. ; 63:5, s. 1431-8
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Journal article (peer-reviewed)abstract
- Huntington disease (HD) is an autosomal dominant neurodegenerative disorder characterized by motor disturbance, cognitive loss, and psychiatric manifestations. The disease is associated with a CAG trinucleotide-repeat expansion in the Huntington gene (IT15) on chromosome 4p16.3. One family with a history of HD was referred to us initially for predictive testing using linkage analysis. However, the chromosome 4p region was completely excluded by polymorphic markers, and later no CAG-repeat expansion in the HD gene was detected. To map the disease trait segregating in this family, whole-genome screening with highly polymorphic dinucleotide-, trinucleotide-, and tetranucleotide-repeat DNA markers was performed. A positive LOD score of 3.01 was obtained for the marker D20S482 on chromosome 20p, by two-point LOD-score analysis with the MLINK program. Haplotype analysis indicated that the gene responsible for the disease is likely located in a 2.7-cM region between the markers D20S193 and D20S895. Candidate genes from the mapping region were screened for mutations.
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| 7. |
- Fissum, Kevin, et al.
(author)
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High-resolution measurement of the 12C(γ,p)11B reaction to excited states for Eγ=50–70MeV
- 1998
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In: Physical Review C: covering nuclear physics. - 2469-9985. ; 58:4, s. 2167-2173
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Journal article (peer-reviewed)abstract
- Relative population of states in 11B following the 12C(γ,p) reaction has been measured with high resolution using the deexcitation γ-ray technique. The states near 7 MeV in 11B are clearly resolved and the measured population clarifies earlier conflicting data. Comparison of the results with new calculations indicates the importance of both one-nucleon and multinucleon processes.
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| 8. |
- Halldin, S, et al.
(author)
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Continuous long-term measurements of soil-plant-atmosphere variables at an agricultural site
- 1999
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In: AGRICULTURAL AND FOREST METEOROLOGY. - : ELSEVIER SCIENCE BV. - 0168-1923. ; 98-9, s. 75-102
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Journal article (peer-reviewed)abstract
- It is a major challenge in modem science to decrease the uncertainty in predictions of global climate change. One of the largest uncertainties in present-day global climate models resides with the understanding of processes in the soil-vegetation-atmosphe
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| 9. |
- Lundin, Lars-Christer, et al.
(author)
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Continuous long-term measurements of soil-plant-atmosphere variables at a forest site
- 1999
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In: Agricultural and Forest Meteorology. - 0168-1923 .- 1873-2240. ; 98-99, s. 53-73
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Journal article (peer-reviewed)abstract
- It is a major challenge in modem science to decrease the uncertainty in predictions of global climate change. One of the largest uncertainties in present-day global climate models resides with the understanding of processes in the soil-vegetation-atmosphere-transfer (SVAT) system. Continuous, long-term data are needed in order to correctly quantify balances of water, energy and CO2 in this system and to correctly model it. It is the objective of this paper to demonstrate how a combined system of existing sensor, computer, and network technologies could be set up to provide continuous and reliable long-term SVAT-process data from a forested site under almost all environmental conditions. The Central Tower Site (CTS) system was set up in 1993-1994 in a 25 m high boreal forest growing on a highly heterogeneous till soil with a high content of stones and blocks. It has successfully monitored relevant states and fluxes in the system, such as atmospheric fluxes of momentum, heat, water vapour and CO2, atmospheric profiles of temperature, water vapour, CO2, short-and long-wave radiation, heat storage in soil and trees, sap-dow and a variety of ecophysiological properties, soil-water contents and tensions, and groundwater levels, rainfall and throughfall. System uptime has been more than 90% for most of its components during the first 5 years of operation. Results from the first 5 years of operation include e.g., budgets for energy, water and CO2, information on important but rarely occurring events such as evaporation from snow-covered canopies, and reactions of the forest to extreme drought. The carbon budget shows that the forest may be a sink of carbon although it is still growing. The completeness of the data has made it possible to test the internal consistency of SVAT models. The pioneering set-up at the CTS has been adopted by a large number of SVAT-monitoring sites around the world. Questions concerning tower maintenance, long-term calibration plans, maintenance of sensors and data-collection system, and continuous development of the computer network to keep it up to date are, however, only partly of interest as a research project in itself. It is thus difficult to get it funded from usual research-funding agencies. The full value of data generated by the CTS system can best be appreciated after a decade or more of continuous operation. Main uses of the data would be to evaluate how SVAT models handle the natural variability of climate conditions, quantification of water. carbon and energy budgets during various weather conditions, rind development of new parameterisation schemes in global and regional climate models.
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| 12. |
- Proff, S, et al.
(author)
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Electromagnetic polarizabilities of nucleons bound in 40Ca, 16O and 4He
- 1999
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In: Nuclear Physics A. - 0375-9474. ; 646:1, s. 67-82
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Journal article (peer-reviewed)abstract
- Differential cross sections for elastic scattering of photons have been measured for 40Ca at energies of 58 and 74 MeV and for 16O and 4He at 61 MeV, in the angular range from 45° to 150°. Evidence is obtained that there are no significant in-medium modifications of the electromagnetic polarizabilities except for those originating from meson exchange currents.
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| 16. |
- Eliasson, L, et al.
(author)
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Observations of electron conics by the Viking satellite
- 1996
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In: JOURNAL OF GEOPHYSICAL RESEARCH-SPACE PHYSICS. - : AMER GEOPHYSICAL UNION. - 0148-0227. ; 101:A6, s. 13225-13238
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Journal article (other academic/artistic)abstract
- Electron angular distributions peaked at oblique angles to the magnetic field, electron conics, are frequently found in the Viking data at all magnetic local times, but with a maximum in the dusk sector. Several types of electron conics have been observed
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| 17. |
- Eriksson, M.O., et al.
(author)
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Palmoplantar pustulosis : a clinical and immunohistological study
- 1998
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In: British Journal of Dermatology. - : Oxford University Press (OUP). - 0007-0963 .- 1365-2133. ; 138:3, s. 390-398
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Journal article (peer-reviewed)abstract
- Pustulosis palmoplantaris (PPP) is a common chronic skin disease, which is very resistant to treatment. It is not known why the lesions are located in the palms and soles. There are few studies of the disease and in particular studies of the histology. Fifty-nine patients with PPP answered a questionnaire concerning their medical history and 39 of them were clinically examined. Biopsy specimens were taken from involved skin in 22 of the 39 patients and studied immunohistologically for tryptase+ mast cells, EG2+ eosinophils, lipocalin+ neutrophils and CD3+ T lymphocytes. The sweat gland and sweat duct were visualized with AE1/AE3 antibody (cytokeratins 1-8, 10, 14/15, 16, 19). In addition to neutrophils in the pustule and lymphocytes in the upper dermis, there were also large numbers of mast cells and eosinophils in the subpustular area. Numerous eosinophils were present in the pustule. The epidermal part of the eccrine duct was not detectable in any of the specimens from patients with PPP but was present in all of the nine control persons (including two smokers). The results indicate that the acrosyringium is involved in the inflammation and also that mast cells and eosinophils participate in a hitherto unknown way. Of the 39 patients clinically examined, two had previously diagnosed thyroid disease and two had gluten hypersensitivity. Seventeen had one or several abnormal serum concentrations of thyroid-stimulating hormone, thyroxin, antibodies against thyroglobulin or thyroperoxidase and 10 had immunoglobulin (Ig) A antibodies to gliadin. The mean +/- SD for serum IgA and for eosinophil cationic protein was increased. From the questionnaire the most notable finding was that 56 of the 59 patients had been or still were smokers, all of whom had started smoking before the first signs of PPP. We hypothesize that the acrosyringium might be the target for the inflammation and that PPP is linked to autoimmune thyroid disease and smoking.
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| 18. |
- Gannerdahl, Per E., et al.
(author)
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Comparison of electrocardiograms recorded with standardleads and derived from the vectorcardiographic frank leads in high risk patients
- 1997
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In: Intensive Care Medicine. - : Springer Science and Business Media LLC. - 0342-4642 .- 1432-1238. ; 23:10, s. 1049-1055
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Journal article (peer-reviewed)abstract
- Dynamic vectorcardiography (VCG) is increasingly employed for ischaemia monitoring with the use of a computerized method for recording and on-line analysis by the calculation of trend parameters. To elucidate how well the derived electrocardiogram (dECG), calculated from the VCC, compares with the simultaneously registered standard ECG (sECG), dECGs from 17 postoperative cardiac-risk patients and 36 subjects with acute myocardial infarction (AMI) were compared to sECGs, both quantitatively in leads II, III, V2 and V5 and qualitatively. Despite small, but some significant differences, mainly in the amplitudes of precordial leads, the qualitative interpretation by two independent cardiologists showed good agreement between the methods (kappa = 0.72 and 0.67, respectively) for the diagnosis of AMI/ischaemia. The dECG seems to be reliable and can be used clinically in these groups of patients during VCG recordings.
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| 21. |
- Halldin, S, et al.
(author)
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NOPEX - a northern hemisphere climate processes land surface experiment
- 1998
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In: JOURNAL OF HYDROLOGY. - : ELSEVIER SCIENCE BV. - 0022-1694. ; 213:1-4, s. 172-187
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Journal article (peer-reviewed)abstract
- The interface between land surfaces and the atmosphere is a key area in climate research, where lack of basic knowledge prevents us from reducing the considerable uncertainties about predicted changes. Boreal forests play an important, but not well known,
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| 31. |
- Lundin, Anders, et al.
(author)
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Compressibility of C61D2 up to 1 GPa in the temperature range 175 - 345 K
- 1996
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In: Carbon. - : Elsevier Science Ltd.. - 0008-6223 .- 1873-3891. ; 34:9, s. 1119-1121
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Journal article (peer-reviewed)abstract
- We have measured the bulk modulus K for C61D2 up to 1 GPa in the temperature range 175–343 K. For face-centered cubic C61D2 above 290 K, we find an anomalously low value for K below about 0.15 GPa, possibly indicating pressure-induced changes in the structure. The (extrapolated) zero-p bulk modulus K(0) decreases with increasing T from 6.7 GPa at 175 K to 5.2 GPa at 343 K. A comparison with hypothetical expanded f.c.c. C60 with the same lattice constant shows that K(0) values are similar, indicating that the main intermolecular interactions are still between molecular bellies, not the sidegroups.
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| 43. |
- Stahli, M, et al.
(author)
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Preferential water flow in a frozen soil - A two-domain model approach
- 1996
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In: Hydrological Processes. - 0885-6087 .- 1099-1085. ; 10:10, s. 1305-1316
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Journal article (peer-reviewed)abstract
- Earlier modelling studies have shown the difficulty of accurately simulating snowmelt infiltration into frozen soil using the hydraulic model approach. Comparison of model outputs and held measurements have inferred the occurrence of rapid flow even during periods when the soil is still partly frozen. A one-dimensional, physically based soil water and heat model (SOIL) has been complemented with a new two-domain approach option to simulate preferential flow through frozen layers. The ice is assumed to be first formed at the largest water filled pore upon freezing. Infiltrating water may be conducted rapidly through previously air-filled pores which are not occupied by ice; A minor fraction of water is slowly transferred within the liquid water domain, which is absorbed by the solid particles. A model validation with field measurements at a location in the middle-east of Sweden indicated that the two-domain approach was suitable for improving the prediction of drainage during snowmelting. In particular, the correlation between simulated and observed onset of drainage in spring was improved. The validation also showed that the effect of the high flow domain was highly sensitive to the degree of saturation in the topsoil during freezing, as well as to the hydraulic properties at the lower frost boundary regulating the upward water flow to the frozen soil and ice formation.
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| 44. |
- Stahli, M, et al.
(author)
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Soil moisture redistribution and infiltration in frozen sandy soils
- 1999
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In: WATER RESOURCES RESEARCH. - : AMER GEOPHYSICAL UNION. - 0043-1397. ; 35:1, s. 95-103
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Journal article (peer-reviewed)abstract
- Infiltration into frozen soil is a result of the whole climate dynamics of the preceding winter with all its importance for the freezing of the soil. Therefore a predictive infiltration model needs to include a proper description of the main processes of
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| 48. |
- Stähli, M., et al.
(author)
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Soil moisture redistribution and infiltration in frozen sandy soils
- 1999
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In: Water resources research. - 0043-1397 .- 1944-7973. ; 35:1, s. 95-103
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Journal article (peer-reviewed)abstract
- Infiltration into frozen soil is a result of the whole climate dynamics of the preceding winter with all its importance for the freezing of the soil. Therefore a predictive infiltration model needs to include a proper description of the main processes of soil water and heat transfer during season-long periods. Such a model may assume two water-conducting flow domains. A lysimeter experiment was set up with the aim of studying these processes in two different sandy soils. Frequent measurements of total and liquid soil water content, soil temperature, and groundwater level were made during two winters with contrasting meteorological conditions. The main problems in the simulation of the two winters were (1) frost-induced upward water redistribution, (2) rate of infiltration in the initially air-filled pores, and (3) heat transfer caused by snowmelt refreezing in the frozen soil. An extensive calibration of the model suggested that some key empirical parameters were not constant for the two soils and the two seasons. Complementary methods for determining the hydraulic conductivity of frozen unsaturated field soils are necessary to further improve the model.
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