| 1. |
- Gavali, Hamid, et al.
(author)
-
Outcome of Radical Surgical Treatment of Abdominal Aortic Graft and Endograft Infections Comparing Extra-anatomic Bypass with In Situ Reconstruction : A Nationwide Multicentre Study
- 2021
-
In: European Journal of Vascular and Endovascular Surgery. - : Saunders Elsevier. - 1078-5884 .- 1532-2165. ; 62:6, s. 918-926
-
Journal article (peer-reviewed)abstract
- Objective: Abdominal aortic graft and endograft infection (AGI) is primarily treated by resection of the infected graft and restoration of distal perfusion through extra-anatomic bypass (EAB) or in situ reconstruction/repair (ISR). The aim of this study was to compare these surgical strategies in a nationwide multicentre retrospective cohort study.Methods: The Swedish Vascular Registry (Swedvasc) was used to identify surgically treated abdominal AGIs in Sweden between January 1995 and May 2017. The primary aim was to compare short and long term survival, as well as complications for EAB and ISR.Results: Some 126 radically surgically treated AGI patients were identified – 102 graft infections and 24 endograft infections – treated by EAB: 71 and ISR: 55 (23 neo-aorto-iliac systems, NAISs). No differences in early 30 day (EAB 81.7% vs. ISR 76.4%, p =.46), or long term five year survival (48.2% vs. 49.9%, p =.87) were identified. There was no survival difference comparing NAIS to other ISR strategies. The frequency of recurrent graft infection during follow up was similar: EAB 20.3% vs. ISR 17.0% (p =.56). Survival and re-infection rates of the new conduit did not differ between NAIS and other ISR strategies. Age ≥ 75 years (odds ratio [OR] 4.0, confidence interval [CI] 1.1 – 14.8), coronary artery disease (OR 4.2, CI 1.2 – 15.1) and post-operative circulatory complications (OR 5.2, CI 1.2 – 22.5) were associated with early death. Prolonged antimicrobial therapy (> 3 months) was associated with reduced long term mortality (HR 0.3, CI 0.1 – 0.9).Conclusion: In this nationwide multicentre study comparing outcomes of radically treated AGI, no differences in survival or re-infection rate could be identified comparing EAB and ISR.
|
|
| 2. |
- Gavali, Hamid, et al.
(author)
-
Semi-Conservative Treatment Versus Radical Surgery in Abdominal Aortic Graft and Endograft Infections
- 2023
-
In: European Journal of Vascular and Endovascular Surgery. - : Elsevier. - 1078-5884 .- 1532-2165. ; 66:3, s. 397-406
-
Journal article (peer-reviewed)abstract
- Objective: Abdominal aortic graft and endograft infections (AGIs) are rare complications following aortic surgery. Radical surgery (RS) with resection of the infected graft and reconstruction with extra-anatomical bypass or in situ reconstruction is the preferred therapy. For patients unfit for RS, a semi-conservative (SC), graft preserving strategy is possible. This paper aimed to compare survival and infection outcomes between RS and SC treatment for AGI in a nationwide cohort.Methods: Patients with abdominal AGI related surgery in Sweden between January 1995 and May 2017 were identified. The Management of Aortic Graft Infection Collaboration (MAGIC) criteria were used for the definition of AGI. Multivariable regression was performed to identify factors associated with mortality.Results: One hundred and sixty-nine patients with surgically treated abdominal AGI were identified, comprising 43 SC (14 endografts; 53% with a graft enteric fistula [GEF] in total) and 126 RS (26 endografts; 50% with a GEF in total). The SC cohort was older and had a higher frequency of cardiac comorbidities. There was a non-significant trend towards lower Kaplan -Meier estimated five year survival for SC vs. RS (30.2% vs. 48.4%; p = .066). A non-significant trend was identified towards worse Kaplan -Meier estimated five year survival for SC patients with a GEF vs. without a GEF (21.7% vs. 40.1%; p = .097). There were significantly more recurrent graft infections comparing SC with RS (45.4% vs. 19.3%; p < .001). In a Cox regression model adjusting for confounders, there was no difference in five year survival comparing SC vs. RS (HR 1.0, 95% CI 0.6 -1.5).Conclusion: In this national AGI cohort, there was no mortality difference comparing SC and RS for AGI when adjusting for comorbidities. Presence of GEF probably negatively impacts survival outcomes of SC patients. Rates of recurrent infection remain high for SC treated patients.
|
|
| 3. |
- Wagenius, Magnus, et al.
(author)
-
Factors influencing stone-free rate of Extracorporeal Shock Wave Lithotripsy (ESWL) : a cohort study
- 2022
-
In: Scandinavian journal of urology. - : Taylor & Francis. - 2168-1805 .- 2168-1813. ; 56:3, s. 237-243
-
Journal article (peer-reviewed)abstract
- Objective: To evaluate the success rate of Extracorporeal Shock Wave Lithotripsy (ESWL) therapy and identify relevant treatment-specific factors affecting stone-free rate (SFR) after ESWL.Materials and methods: All ESWL treatments in the years 2016-2019, in angelholm Hospital, Skane, Sweden were analysed retrospectively. Primary outcome was stone-free rate (SFR) at 3 months. Univariate logistic regression was used followed by multivariable regression. Lasso analysis was made to adjust for treatment-specific factors such as age, stone size, skin-to-stone distance (SSD), stone attenuation, number of treatments, stone location and presence of a urinary stent.Results: Factors affecting successful ESWL treatment were lower age (p < 0.001), smaller stone size and volume (both p = 0.001). SSD, stone attenuation, sex, laterality and drainage did not have an effect on SFR in this study. After the first ESWL treatment session, 46.7% of the patients were stone-free.Conclusion: Results indicate that stone size and age are the most predictive factors for ESWL outcome. Based on this, we present a simple model for prediction of SFR after ESWL, to be used when counseling patients before ESWL treatment.
|
|
| 4. |
- Ahlbeck Bergendahl, Ida, et al.
(author)
-
Fisk- och skaldjursbestånd i hav och sötvatten 2016 : Resursöversikt
- 2016
-
Reports (other academic/artistic)abstract
- I rapporten kan du ta del av bedömningen som görs av situationen för bestånd som regleras inom ramen för EU:s gemensamma fiskeripolitik (GFP). Bedömningarna baseras på det forskningssamarbete och den rådgivning som sker inom det Internationella Havsforskningsrådet (ICES).De bestånd som förvaltas nationellt baseras på de biologiska underlagen, och rådgivningen i huvudsak på den forskning och övervakning samt analys som bedrivs av Institutionen för akvatiska resurser vid Sveriges lantbruksuniversitet (SLU Aqua) samt yrkesfiskets rapportering.Rapporten omfattar 41 fiskarter uppdelade i olika bestånd, samt sju skal- och blötdjursarter.Nytt för årets upplaga är kapitlet om ekosystemtjänster. Avsnittet beskriver de fördelar människan får genom ekosystemen, till exempel hur fisk och skaldjur kommer till nytta för människan genom föda, rekreation och biologisk mångfald. Nytt för i år är också att rapportens diagram och figurer anpassats för läsare med defekt färgseende.Översikten är utarbetad av SLU Aqua på uppdrag av Havs- och vattenmyndigheten.
|
|
| 5. |
|
|
| 6. |
- Ahlbeck Bergendahl, Ida, et al.
(author)
-
Fisk- och skaldjursbestånd i hav och sötvatten 2017 : Resursöversikt
- 2017
-
Reports (other academic/artistic)abstract
- I rapporten kan du ta del av bedömningen som görs av situationen för bestånd som regleras inom ramen för EU:s gemensamma fiskeripolitik (GFP). Bedömningarna baseras på det forskningssamarbete och den rådgivning som sker inom det Internationella Havsforskningsrådet (ICES).De bestånd som förvaltas nationellt baseras på de biologiska underlagen, och rådgivningen i huvudsak på den forskning och övervakning samt analys som bedrivs av Institutionen för akvatiska resurser vid Sveriges lantbruksuniversitet (SLU Aqua) samt yrkesfiskets rapportering.Rapporten omfattar 41 fiskarter och sju skaldjursarter.Nytt för i år är att vi även beskriver fritidsfisket mer utförligt. Det fisket får allt större betydelse för utvecklingen av många av Sveriges bestånd av fisk- och skaldjur, till exempel sötvattens- och kustlevande arter som abborre, gädda, gös, lax, röding och öring, liksom marina arter som torsk och hummerÖversikten är utarbetad av SLU Aqua på uppdrag av Havs- och vattenmyndigheten.
|
|
| 7. |
- Andersson, Jan, et al.
(author)
-
Fisk- och skaldjursbestånd i hav och sötvatten 2015 : Resursöversikt
- 2015
-
Reports (other academic/artistic)abstract
- I rapporten kan du ta del av bedömningen som görs av situationen för bestånd som regleras inom ramen för EU:s gemensamma fiskeripolitik (GFP). Bedömningarna baseras på det forskningssamarbete och den rådgivning som sker inom det Internationella Havsforskningsrådet (ICES).De bestånd som förvaltas nationellt baseras på de biologiska underlagen och rådgivningen i huvudsak på den forskning och övervakning samt analys som bedrivs av Institutionen för akvatiska resurser (SLU Aqua) vid Sveriges lantbruksuniversitet (SLU) samt yrkesfiskets rapportering.Rapporten omfattar 40 fiskarter uppdelade i olika bestånd, samt sex skal-och blötdjursarter.Nytt för årets upplaga är en beskrivning av hur de provfisken som ligger till grund för analys och rådgivning utförs.Översikten är utarbetad av Sveriges lantbruksuniversitet (SLU), Institutionen för akvatiska resurser (SLU Aqua), på uppdrag av Havs- och vattenmyndigheten.
|
|
| 8. |
- Andersson, Magnus, et al.
(author)
-
Fiskbestånd och miljö i hav och sötvatten : Resurs- och miljööversikt 2012
- 2012
-
Reports (other academic/artistic)abstract
- Detta är den nionde utgåvan av den samlade översikten över fisk- och kräftdjursbeståndens status i våra vatten. Kunskap om fiskbestånden och miljön är en förutsättning för att utnyttjandet av fiskresurserna skall bli bärkraftigt. För svenska vattenområden beskrivs miljöutvecklingen i ett ekosystemsperspektiv, dels för att tydliggöra fiskens ekologiska roll och beskriva yttre miljöfaktorer som påverkar fiskbestånden, dels för att belysa fiskets effekter på miljön.Fiskbestånd och miljö i hav och sötvatten är utarbetad av Sveriges lantbruksuniversitet (SLU), Institutionen för akvatiska resurser (SLU Aqua), på uppdrag av Havs- och vattenmyndigheten. Rapporten sammanfattar utveckling och beståndsstatus för de kommersiellt viktigaste fisk- och kräftdjursarterna i våra vatten. Bedömningar och förvaltningsråd är baserade på Internationella Havsforskningsrådets (ICES) rådgivning, SLU Aquas nationella och regionala provfiskedata, samt yrkesfiskets rapportering.
|
|
| 9. |
|
|
| 10. |
|
|
| 11. |
|
|
| 12. |
|
|
| 13. |
- Bergström, Ulf, et al.
(author)
-
Long-term effects of no-take zones in Swedish waters
- 2022
-
Reports (other academic/artistic)abstract
- Marine protected areas (MPAs) are increasingly established worldwide to protect and restore degraded ecosystems. However, the level of protection varies among MPAs and has been found to affect the outcome of the closure. In no-take zones (NTZs), no fishing or extraction of marine organisms is allowed. The EU Commission recently committed to protect 30% of European waters by 2030 through the updated Biodiversity Strategy. Importantly, one third of these 30% should be of strict protection. Exactly what is meant by strict protection is not entirely clear, but fishing would likely have to be fully or largely prohibited in these areas. This new target for strictly protected areas highlights the need to evaluate the ecological effects of NTZs, particularly in regions like northern Europe where such evaluations are scarce. The Swedish NTZs made up approximately two thirds of the total areal extent of NTZs in Europe a decade ago. Given that these areas have been closed for at least 10 years and can provide insights into long-term effects of NTZs on fish and ecosystems, they are of broad interest in light of the new 10% strict protection by 2030 commitment by EU member states.In total, eight NTZs in Swedish coastal and offshore waters were evaluated in the current report, with respect to primarily the responses of focal species for the conservation measure, but in some of the areas also ecosystem responses. Five of the NTZs were established in 2009-2011, as part of a government commission, while the other three had been established earlier. The results of the evaluations are presented in a synthesis and also in separate, more detailed chapters for each of the eight NTZs. Overall, the results suggest that NTZs can increase abundances and biomasses of fish and decapod crustaceans, given that the closed areas are strategically placed and of an appropriate size in relation to the life cycle of the focal species. A meta-regression of the effects on focal species of the NTZs showed that CPUE was on average 2.6 times higher after three years of protection, and 3.8 times higher than in the fished reference areas after six years of protection. The proportion of old and large individuals increased in most NTZs, and thereby also the reproductive potential of populations. The increase in abundance of large predatory fish also likely contributed to restoring ecosystem functions, such as top-down control. These effects appeared after a 5-year period and in many cases remained and continued to increase in the longer term (>10 years). In the two areas where cod was the focal species of the NTZs, positive responses were weak, likely as an effect of long-term past, and in the Kattegat still present, recruitment overfishing. In the Baltic Sea, predation by grey seal and cormorant was in some cases so high that it likely counteracted the positive effects of removing fisheries and led to stock declines in the NTZs. In most cases, the introduction of the NTZs has likely decreased the total fishing effort rather than displacing it to adjacent areas. In the Kattegat NTZ, however, the purpose was explicitly to displace an unselective coastal mixed bottom-trawl fishery targeting Norway lobster and flatfish to areas where the bycatches of mature cod were smaller. In two areas that were reopened to fishing after 5 years, the positive effects of the NTZs on fish stocks eroded quickly to pre-closure levels despite that the areas remained closed during the spawning period, highlighting that permanent closures may be necessary to maintain positive effects.We conclude from the Swedish case studies that NTZs may well function as a complement to other fisheries management measures, such as catch, effort and gear regulations. The experiences from the current evaluation show that NTZs can be an important tool for fisheries management especially for local coastal fish populations and areas with mixed fisheries, as well as in cases where there is a need to counteract adverse ecosystem effects of fishing. NTZs are also needed as reference for marine environmental management, and for understanding the effects of fishing on fish populations and other ecosystem components in relation to other pressures. MPAs where the protection of both fish and their habitats is combined may be an important instrument for ecosystembased management, where the recovery of large predatory fish may lead to a restoration of important ecosystem functions and contribute to improving decayed habitats.With the new Biodiversity Strategy, EUs level of ambition for marine conservation increases significantly, with the goal of 30% of coastal and marine waters protected by 2030, and, importantly, one third of these areas being strictly protected. From a conservation perspective, rare, sensitive and/or charismatic species or habitats are often in focus when designating MPAs, and displacement of fisheries is then considered an unwanted side effect. However, if the establishment of strictly protected areas also aims to rebuild fish stocks, these MPAs should be placed in heavily fished areas and designed to protect depleted populations by accounting for their home ranges to generate positive outcomes. Thus, extensive displacement of fisheries is required to reach benefits for depleted populations, and need to be accounted for e.g. by specific regulations outside the strictly protected areas. These new extensive EU goals for MPA establishment pose a challenge for management, but at the same time offer an opportunity to bridge the current gap between conservation and fisheries management.
|
|
| 14. |
- Berkström, Charlotte, et al.
(author)
-
Rapid effects of a fishing closure on whitefish (Coregonus maraena) in the northern Baltic Sea
- 2021
-
In: Boreal Environment Research. - 1239-6095 .- 1797-2469. ; 26, s. 89-104
-
Journal article (peer-reviewed)abstract
- Areas closed to fishing year-round (no-take zones, NTZs) or during spawning time (spawning closures) are used as a management tool to increase declining fish populations. We evaluated the effects of a 147 km2 NTZ and a 3980 km2 spawning closure on whitefish populations in the northern Baltic Sea, and also accounted for fish consumption by seals and cormorants. Fish monitoring with multimesh gillnets in 2011–2016 showed a significant increase in catch per unit effort (CPUE) of mature whitefish (> 30 cm) both in the spawning closure and the NTZ compared with the reference area open to fishing. The rate of increase was significantly higher in the NTZ than in the spawning closure. Our results suggest that NTZs may strengthen coastal fish populations in temperate regions and that also seasonal closures under a critical period of the life cycle may benefit the populations.
|
|
| 15. |
- Bobjer, Johannes, et al.
(author)
-
Location of retroperitoneal lymph node metastases in upper tract urothelial carcinoma : results from a prospective lymph node mapping study
- 2023
-
In: European Urology Open Science. - : Elsevier. - 2666-1691 .- 2666-1683. ; 57, s. 37-44
-
Journal article (peer-reviewed)abstract
- Background: There is limited information on the distribution of retroperitoneal lymph node metastases (LNMs) in upper tract urothelial carcinoma (UTUC).Objective: To investigate the location of LNMs in UTUC of the renal pelvis or proximal ureter and short-term complications after radical nephroureterectomy (RNU) with lymph node dissection (LND).Design, setting, and participants: This was a prospective Nordic multicenter study (four university hospitals, two county hospitals). Patients with clinically suspected locally advanced UTUC (stage >T1) and/or clinical lymph node–positive (cN+) disease were invited to participate. Participants underwent RNU and fractionated retroperitoneal LND using predefined side-specific templates.Outcome measurements and statistical analysis: The location of LNMs in the LND specimen and retroperitoneal lymph node recurrences during follow-up was recorded. Postoperative complications within 90 d of surgery were ascertained from patient charts. Descriptive statistics were used.Results and limitations: LNMs were present in the LND specimen in 23/100 patients, and nine of 100 patients experienced a retroperitoneal recurrence. Distribution per side revealed LNMs in the LND specimen in 11/38 (29%) patients with right-sided tumors, for whom the anatomically larger, right-sided template was used, in comparison to 12/62 (19%) patients with left-sided tumors, for whom a more limited template was used. High-grade complications (Clavien grade ≥3) within 90 d of surgery were registered for 13/100 patients. The study is limited in size and not powered to assess survival estimates.Conclusions: The suggested templates that we prospectively applied for right-sided and left-sided LND in patients with advanced UTUC included the majority of LNMs. High-grade complications directly related to the LND part of the surgery were limited.Patient summary: This study describes the location of lymph node metastases in patients with cancer in the upper urinary tract who underwent surgery to remove the affected kidney and ureter. The results show that most metastases occur within the template maps for lymph node surgery that we investigated, and that this surgery can be performed with few severe complications.
|
|
| 16. |
- Bryhn, Andreas, et al.
(author)
-
A continuous involvement of stakeholders promotes the ecosystem approach to fisheries in the 8-fjords area on the Swedish west coast
- 2017
-
In: ICES Journal of Marine Science. - : Oxford University Press (OUP). - 1054-3139 .- 1095-9289. ; 74, s. 431–442-
-
Journal article (peer-reviewed)abstract
- The coastal marine environment in the 8-fjords area on the Swedish west coast has been subjected to various stakeholder co-management initiatives since 1999. Stakeholders and authorities have acted by supporting and implementing gradually stricter fishing restrictions following the collapse in the 1970s of several demersal fish stocks and their apparent lack of recovery. Moreover, concerns have been raised regarding a locally sharp depletion of eelgrass meadows, in addition to an apparent increase in the number of seals and cormorants. The present 8-fjords initiative applies a cross-sector approach to environmental management and thus also addresses various types of environmental pollution. This study has compared the environmental work around the 8-fjords to 15 principles regarding the ecosystem approach to fisheries (EAF). The main strength that has been identified among the EAF principles is the continuous involvement of stakeholders. Among weaknesses in the EAF is the scarcity of suitable indicators that are necessary for appropriate monitoring, especially biomasses of functional groups as well as economic and social indicators. Many environmental problems in the fjords remain and it is possible that improved adherence to EAF principles will facilitate solving some problems and alleviating others. Moreover, the application of the EAF in practice in the 8-fjords can serve as a guiding example for co-managing other aquatic ecosystems towards ecological, economic, and social sustainability. The experiences from the 8-fjords initiative, including its extensive stakeholder involvement, may serve as a practical EAF example to be studied by researchers and managers globally.
|
|
| 17. |
- Bryhn, Andreas, et al.
(author)
-
Fisk- och skaldjursbestånd i hav och sötvatten 2019 : Resursöversikt
- 2020
-
Reports (other academic/artistic)abstract
- Fisken i havet är en resurs som rör sig fritt över nationella gränser. EU har därför en gemensam fiskeripolitik (GFP). Många arter som är viktiga för Sverige regleras inte i GFP och förvaltas därför nationellt.Denna rapport syftar till att:beskriva utvecklingen av fiskeripolitikenförklara den nuvarande politikens mål och regelverk och dess relation till mål och regler på miljöområdetförklara politikens nationella genomförande och det nationella handlingsutrymmetexemplifiera hur Havs- och vattenmyndigheten arbetat med att reglera fisket.
|
|
| 18. |
- Bryhn, Andreas, et al.
(author)
-
Fisk- och skaldjursbestånd i hav och sötvatten 2020 : Resursöversikt
- 2021
-
Reports (other academic/artistic)abstract
- I rapporten kan du ta del av bedömningen som görs av situationen för bestånd som regleras inom ramen för EU:s gemensamma fiskeripolitik (GFP). Bedömningarna baseras på det forskningssamarbete och den rådgivning som sker inom det Internationella Havsforskningsrådet (ICES). Totalt redovisas underlag och råd för 48 fisk- och skaldjursarter.De bestånd som förvaltas nationellt baseras på de biologiska underlagen, och rådgivningen i huvudsak på den forskning och övervakning samt analys som bedrivs av Institutionen för akvatiska resurser vid Sveriges lantbruksuniversitet (SLU Aqua) samt yrkesfiskets rapportering.
|
|
| 19. |
- Bryhn, Andreas, et al.
(author)
-
Kunskapsunderlag om möjliga icke-torskfiskerelaterade åtgärder för att torskbestånd ska bevaras och återhämta sig i svenska vatten
- 2020
-
Reports (peer-reviewed)abstract
- Torsk (Gadus morhua) är en viktig art för marina ekosystem i Sverige, där den har en strukturerande och reglerande funktion i relation till andra arter. Torsken har under historiens gång även spelat en viktig roll för samhället i Sverige inom dess nuvarande gränsers område (Bohuslän har t.ex. inte alltid tillhört Sverige), som en målart för fiske. Samtliga torskbestånd som återfinns i havsområdena runt Sverige har nu dålig status och det internationella havsforskningsrådet ICES rekommenderar låg eller ingen fångst, beroende på bestånd. Utöver riktat fiske påverkas dock torsken av en rad andra faktorer som exempelvis bifångster i annat fiske, syrebrist, klimatförändringar, predatorer, parasiter, bottenpåverkan av trålning, förlust av uppväxtmiljöer, födobrist, tiaminbrist och giftiga ämnen. Denna rapport diskuterar möjligheter att skydda och bevara torsken på sätt som kan komplettera begränsningar i det riktade torskfisket. Torskens situation är komplex och rapporten är därför skriven utifrån ett ekosystemperspektiv för att möjliggöra en bredare ansats i förvaltningen av torskbestånd i svenska vatten, där alla relevanta påverkansfaktorer bör beaktas. Det bör poängteras att denna rapport inte har gjort någon ny utredning av påverkansfaktorernas effekter, utan har istället gjort en litteratursammanställning och en kvalitativ analys. Vi har ändå valt att lyfta fram vissa åtgärder som särskilt potentiellt betydelsefulla - en samlad kvalitativ expertbedömning som rangordnar olika åtgärders effektivitet för återuppbyggnad per bestånd, se avsnitt 6 i rapporten.
|
|
| 20. |
- Bryhn, Andreas, et al.
(author)
-
Which factors can affect the productivity and dynamics of cod stocks in the Baltic Sea, Kattegat and Skagerrak?
- 2022
-
In: Ocean and Coastal Management. - : Elsevier BV. - 0964-5691 .- 1873-524X. ; 223
-
Research review (peer-reviewed)abstract
- Stocks of Atlantic cod (Gadus morhua) in the Baltic Sea, Kattegat and Skagerrak (N. Europe) have been strongly exploited for decades bringing them into an enduringly depleted status. Scientific cod stock related advice for targeted and mixed fisheries is provided on an annual basis by the International Council for Exploration of the Sea. This advice forms a basis for ministerial decisions on, e.g., the total allowable catch and management plans. Despite measures to reduce fishing-induced mortality of cod, such as catch and effort restrictions, increased gear selectivity, closed areas and seasons, clear signs of recovery are yet to be seen. Thus, traditional advice for the management of these stocks may have to be complemented by advice on supporting measures focusing on other pressures hampering the recovery of cod. The present study elaborates on potential supportive measures for cod stock recovery in the Baltic Sea, Kattegat, and Skagerrak (including local populations where applicable), based on current knowledge. The list of measures presented here is the outcome of in-depth discussions on the state-of-the-art knowledge, among cod experts and further with stakeholders with the aim to follow principles of ecosystem-based fisheries management. Following the identification of different pressures on and prerequisites for the separate stocks, the listed measures differ between stocks and include cod bycatch mortality reduction, alterations in fisheries affecting food sources for cod, restocking, protection of juvenile habitats, and reduced predation. The literature review and the list of measures are intended to provide decision-support for managers and policymakers aiming to provide conditions for the cod stocks to recover.
|
|
| 21. |
- Casini, Michele, et al.
(author)
-
Hypoxic areas, density-dependence and food limitation drive the body condition of a heavily exploited marine fish predator
- 2016
-
In: Royal Society Open Science. - : The Royal Society. - 2054-5703. ; 3
-
Journal article (peer-reviewed)abstract
- Investigating the factors regulating fish condition is crucial in ecology and the management of exploited fish populations. The body condition of cod (Gadus morhua) in the Baltic Sea has dramatically decreased during the past two decades, with large implications for the fishery relying on this resource. Here, we statistically investigated the potential drivers of the Baltic cod condition during the past 40 years using newly compiled fishery-independent biological data and hydrological observations. We evidenced a combination of different factors operating before and after the ecological regime shift that occurred in the Baltic Sea in the early 1990s. The changes in cod condition related to feeding opportunities, driven either by density-dependence or food limitation, along the whole period investigated and to the fivefold increase in the extent of hypoxic areas in the most recent 20 years. Hypoxic areas can act on cod condition through different mechanisms related directly to species physiology, or indirectly to behaviour and trophic interactions. Our analyses found statistical evidence for an effect of the hypoxia-induced habitat compression on cod condition possibly operating via crowding and density-dependent processes. These results furnish novel insights into the population dynamics of Baltic Sea cod that can aid the management of this currently threatened population.
|
|
| 22. |
|
|
| 23. |
- Costalago, David, et al.
(author)
-
The necessity of a holistic approach when managing marine mammal–fisheries interactions : Environment and fisheries impact are stronger than seal predation
- 2019
-
In: Ambio. - : Springer Science and Business Media LLC. - 0044-7447 .- 1654-7209. ; 48:6, s. 552-564
-
Journal article (peer-reviewed)abstract
- Seal populations are recovering in many regions around the world and, consequently, they are increasingly interacting with fisheries. We used an Ecopath with Ecosim model for the offshore Central Baltic Sea to investigate the interactions between the changes in fish stocks and grey seal (Halichoerus grypus) population under different fishing and environmental scenarios for the twenty-first century. The assumed climate, eutrophication and cod (Gadus morhua) fisheries scenarios modified seal predation impacts on fish. Fish biomass and catches are more affected by fishing mortality and the environment than by seal predation. Our results highlight that the impacts of the increasing seal population on lower trophic levels are complex; thus, we emphasize the need to consider a range of possible ecosystem contexts when evaluating potential impacts of top predators. Finally, we suggest that an increasing seal population is not likely to hinder the preservation of the main Baltic fish stocks.
|
|
| 24. |
- Florin, Ann-Britt, et al.
(author)
-
Effects of a large northern European no-take zone on flatfish populations
- 2013
-
In: Journal of Fish Biology. - : Wiley. - 0022-1112 .- 1095-8649. ; 83:4, s. 939-962
-
Journal article (peer-reviewed)abstract
- In March 2006, a 360km(2) no-take zone (NTZ) was established north of Gotland in the central Baltic Sea, with the purpose to scientifically evaluate the effects of a fishing ban on flatfish populations. A monitoring programme was set up to study the populations in the NTZ and in a reference area east of Gotland where the fishing pressure was high. The programme included fishing with multimesh survey nets, modelling of potential larval export and estimation of fish consumption by large marine predators. Overall, the results showed a clear positive effect of the NTZ on turbot Scophthalmus maximus, with higher densities in the closed area compared with the fished area and also higher densities after closure compared with before. The NTZ also had older individuals and a more even sex ratio. This, in combination with a high potential for larval export from the NTZ to Gotland, shows that the marine reserve may be important for maintaining a viable S. maximus stock at Gotland. Also, for flounder Platichthys flesus, the densities were higher in the NTZ compared to the reference area and there was a net larval export to the fished area. For both species, density-dependent growth was evident, with a lower length at age in the closed area. Potential predation by grey seal Halichoerus grypus and great cormorant Phalacrocorax carbo sinesis on flatfishes, that could hamper the evaluation of the marine reserve, was also addressed. Taken together, the results show that there are clear benefits of the fishing ban for both flatfish species within the NTZ, while the net effects on fisheries are difficult to quantify.
|
|
| 25. |
|
|
| 26. |
- Florin, Ann-Britt, et al.
(author)
-
Uppföljning av fredningsområdet vid Gotska Sandön 2006-2010
- 2011
-
Reports (other academic/artistic)abstract
- I mars 2006 infördes ett 360 km2 stort fiskefritt område kring Gotska Sandön, i syfte att utvärdera effekterna av fiskeförbud på fiskbestånd. Ett uppföljningsprogram utarbetades för att studera bestånden i försöksområdet och två referensområden, ett öster om Gotland, där fisketrycket är högt, och ett vid det delvis fredade Hoburgs bank. Gotska Sandön hade ett lägre fisketryck än referensområdena redan innan det fiskefria området infördes, vilket möjliggjorde en utvärdering av effekterna på fiskbestånd med ett kortvarigt uppföljningsprogram. Uppföljningsprogrammet inkluderade nätprovfisken, märkning av plattfisk samt modellering av larvspridning. En översikt av resultaten visas i sammanfattningstabellen (sidan 8–9). Sammantaget visar resultaten en tydlig positiveffekt av det fiskefria området på piggvar(Scoph–thalmus maximus), med högre tätheter vid Gotska Sandön jämfört med Gotland och även högre tätheter efter fredningen jämfört med före. Detta i kombination med en högre reproduktiv potential och en potentiell larvexport från Gotska Sandön till Gotland, visar att fredningsområdet kan vara viktigt för att långsiktigt upprätthålla ett livskraftigt piggvarsbestånd vid Gotland. För skrubbskädda (Platichthys flesus)är effekten av fredningsområdet inte lika tydlig, men även här är tätheten högre vid Gotska Sandön än i referensområdena och det finns potential för larvexport från Gotska Sandön till Gotland. För torsk (Gadus morhua) ses ingen effekt av reservatet, vilket var ett förväntat resultat. Torsken har inte, till skillnad från plattfisken, lokala bestånd runt Gotland utan utgör en periferdel av det stora ostliga beståndet av torsk i Östersjön och styrs därför mer av vad som händer i resten av beståndet än vad som händer vid Gotska Sandön. Förutom att fungera som ett viktigtreproduktionsområde för plattfisk utgör fredningsområdet, som ligger i ett marintnaturreservat, även ett viktigt referensområde för forskning, eftersom det är ett av få områden i Östersjön som inte är starktpåverkat av mänsklig aktivitet. För att säkerställa dessa viktiga funktioner bör området därför fortsättningsvis vara stängt för fiske.
|
|
| 27. |
- Fridriksson, Jon Örn, et al.
(author)
-
Long-term adverse effects after retropubic and robot-assisted radical prostatectomy : Nationwide, population-based study
- 2017
-
In: Journal of Surgical Oncology. - : Wiley. - 0022-4790 .- 1096-9098. ; 116:4, s. 500-506
-
Journal article (peer-reviewed)abstract
- Background and Objectives: Surgery for prostate cancer is associated with adverse effects. We studied long-term risk of adverse effects after retropubic (RRP) and robot-assisted radical prostatectomy (RARP).Methods: In the National Prostate Cancer Register of Sweden, men who had undergone radical prostatectomy (RP) between 2004 and 2014 were identified. Diagnoses and procedures indicating adverse postoperative effects were retrieved from the National Patient Register. Relative risk (RR) of adverse effects after RARP versus RRP was calculated in multivariable analyses adjusting for year of surgery, hospital surgical volume, T stage, Gleason grade, PSA level at diagnosis, patient age, comorbidity, and educational level.Results: A total of 11 212 men underwent RRP and 8500 RARP. Risk of anastomotic stricture was lower after RARP than RRP, RR for diagnoses 0.51 (95%CI = 0.42-0.63) and RR for procedures 0.46 (95%CI = 0.38-0.55). Risk of inguinal hernia was similar after RARP and RRP but risk of incisional hernia was higher after RARP, RR for diagnoses 1.48 (95%CI = 1.01-2.16), and RR for procedures 1.52 (95%CI = 1.02-2.26).Conclusions: The postoperative risk profile for RARP and RRP was quite similar. However, risk of anastomotic stricture was lower and risk of incisional hernia higher after RARP.
|
|
| 28. |
- Grabe, Magnus J., et al.
(author)
-
Tailored perioperative antimicrobial prophylaxis in urological surgery : myth or reality?
- 2017
-
In: Current Opinion in Urology. - 0963-0643 .- 1473-6586. ; 27:2, s. 112-119
-
Research review (peer-reviewed)abstract
- Purpose of review The controversies surrounding perioperative antimicrobial prophylaxis (AMP) are about the use and especially misuse of antibiotics. The overall lack of evidence to facilitate a rational perioperative AMP policy in urological surgery and the postoperative infectious complications remain a challenge. Therefore, a basic tool to aid decision-making would be useful. A model based on the patients' risk factors, the level of contamination and grading of surgical procedures is discussed.Recent findings A series of studies have shown that infectious complications and healthcare-associated infections remain consistently at an average of 10%, with a great variation in frequency dependent on the patients' preoperative status and the type, severity and contamination level of the surgical procedure. Preoperative patient assessment and preparation are key factors for well tolerated surgery and recovery. Adherence to the guidelines appears to reduce both the prescription of antimicrobials and the total costs without risking the patient outcome. Several studies of a series of interventions such as cystoscopy, endoscopic stone surgery and selected clean-contaminated interventions give support to the model. Bacteriuria, upgrading the patient to the contaminated level, requires preoperative control.Summary The discussed model assists the urologists in decision-making on perioperative AMP and contributes to a responsible use of antibiotics.
|
|
| 29. |
- Gårdmark, Anna, et al.
(author)
-
Does predation by grey seals (Halichoerus grypus) affect Bothnian Sea herring stock estimates?
- 2012
-
In: ICES Journal of Marine Science. - : Oxford University Press (OUP). - 1054-3139 .- 1095-9289. ; 69, s. 1448-1456
-
Journal article (peer-reviewed)abstract
- Mortality of small pelagic fish due to marine mammals is generally considered to be low compared with other sources of mortality. With recent recoveries of marine mammal predators worldwide, this may no longer hold. The grey seal (Halichoerus grypus) population in the Bothnian Sea has increased fivefold since 1985. Its main prey, herring (Clupea harrengus), is a key species for fisheries in the region. Yet, current stock assessments assume constant natural mortality, leading to a risk of biased stock estimates with increasing predation and misleading analyses of herring population dynamics. We estimated grey seal predation from diet data and reanalysed herring spawning stock biomass (SSB) during 1973-2009. Accounting for predation increased the herring SSB 16% (maximum 19%), but this was within the confidence intervals when ignoring predation. Although mortality in older individuals was inflated when accounting for seal predation, this did not change the conclusions about drivers of herring dynamics. Accounting for grey seal predation is important for abundance estimates of old herring, but currently not for SSB estimates, given the great uncertainties in the standard assessment. The grey seal impact on Bothnian Sea herring will need to be reassessed if stock age composition, grey seal feeding preferences, or total stock development change.
|
|
| 30. |
|
|
| 31. |
- Hansson, Julia, et al.
(author)
-
HOPE - Hydrogen fuel cells solutions in Nordic shipping. Project summary : A Nordic Maritime Transport and Energy Research Programme Project
- 2023
-
Reports (other academic/artistic)abstract
- The Nordic countries aim for a carbon-neutral Nordic region. Maritime transport is one of the key remaining sectors to decarbonize and is important from a Nordic perspective due to the relatively large Nordic involvement in this industry. The HOPE project addresses how regional shipping in the Nordic region can do the transition to become fossil-free. The project aims at clarifying the potential role of hydrogen based marine solutions in reducing the Nordic greenhouse gas (GHG) emissions. In the centre of the project is a ship concept where a typical RoPax-vessel with operating distances of around 100 nautical miles is designed for including operation with hydrogen as fuel and fuel cells for energy conversion. The overall design of the concept ship is compared with selected other fuel alternatives from a cost perspective. Further, both the conditions for designing such a ship and the consequences are studied. The conditions include technical design and costs of fuel systems and handling, powertrains etc. but also an analysis of barriers and drivers for the realisation of hydrogen solutions for shipping, such as economic, legal, and policy issues. For example, in terms of drivers, policy options needed to accelerate the uptake of hydrogen based marine solutions are assessed. Strategies and the potential of producing these fuels in the Nordic region are also reviewed from a shipping perspective. A realistic potential for uptake of these technologies/fuels by Nordic shipping are assessed and the benefits regarding lower emissions of GHGs and air pollutants are estimated. This report summarizes the assessments made in the HOPE project including main findings.
|
|
| 32. |
- Hansson, Sture, et al.
(author)
-
Competition for the fish - fish extraction from the Baltic Sea by humans, aquatic mammals, and birds
- 2018
-
In: ICES Journal of Marine Science. - : Oxford University Press (OUP). - 1054-3139 .- 1095-9289. ; 75:3, s. 999-1008
-
Journal article (peer-reviewed)abstract
- Seals and fish-eating birds have increased in the Baltic Sea and there is concern that they compete with fisheries. Using data from around year 2010, we compare consumption of different fish species by seals and birds to the catch in the commercial and recreational fishery. When applicable this is done at the geographical resolution of ICES subdivisions. Predation by birds and mammals likely has limited impact on the populations of the commercially most important species (herring, sprat, and cod). In the central and southern Baltic, seals and birds consume about as much flatfish as is caught by the fishery and competition is possible. Birds and seals consume 2-3 times as much coastal fish as is caught in the fishery. Many of these species are important to the fishery (e. g. perch and whitefish) and competition between wildlife and the fishery is likely, at least locally. Estimated wildlife consumption of pike, sea trout and pikeperch varies among ICES subdivisions and the degree of competition for these species may differ among areas. Competition between wildlife and fisheries need to be addressed in basic ecosystem research, management and conservation. This requires improved quantitative data on wildlife diets, abundances and fish production.
|
|
| 33. |
- Hansson, Sture, 1953-, et al.
(author)
-
Response to comments by Heikinheimo et al. (in press) on Hansson et al. (2018): competition for the fish—fish extraction from the Baltic Sea by humans, aquatic mammals, and birds
- 2018
-
In: ICES Journal of Marine Science. - : Oxford University Press (OUP). - 1054-3139 .- 1095-9289. ; 75:5, s. 1837-1839
-
Journal article (peer-reviewed)abstract
- As discussions and debates are crucial to science, we appreciate the comments by Heikinheimo et al. (in press) on our article on competition for Baltic Sea fish resources between fishery and wildlife. We cannot see that the comments by Heikinheimo et al. changes the general conclusion derived in our original article—that there are cases of competition between wildlife and fisheries in the Baltic Sea, although not for all species and not to the same extent everywhere. Our responses are structured in the same order as the comments by Heikinheimo et al.
|
|
| 34. |
- Herlevi, Heidi, et al.
(author)
-
Environmental abundances of the non-native round goby Neogobius melanostomus influence feeding of native fish predators
- 2023
-
In: Journal of Fish Biology. - : Wiley-Blackwell. - 0022-1112 .- 1095-8649. ; 102:6, s. 1340-1357
-
Journal article (peer-reviewed)abstract
- The authors assessed the importance of the round goby Neogobius melanostomus as prey for three native predatory fish species, Atlantic cod Gadus morhua, European perch Perca fluviatilis and northern pike Esox lucius, in a northern and southern area of the Baltic Proper, using a combination of visual analysis and DNA metabarcoding of predator stomach contents. To explore the influence of environmental abundances of N. melanostomus on predation, they related the occurrence of N. melanostomus in predator diets to its abundance in survey fishing. Gadus morhua and E. lucius in the southern area showed the highest tendency to feed on N. melanostomus when it was abundant, as N. melanostomus occurred in up to 100% of stomachs and constituted up to 88% of the total diet volume proportion. The diet contribution of N. melanostomus was associated with N. melanostomus abundances for G. morhua and E. lucius, and when N. melanostomus was abundant, these predators exhibited lower prey richness and a higher degree of piscivory. G. morhua and P. fluviatilis also fed less on crustacean prey when N. melanostomus was abundant. The high importance of N. melanostomus in diets of native fish predators may modify indirect interactions between N. melanostomus and native prey species in invaded coastal communities.
|
|
| 35. |
- Holm, Alexander, et al.
(author)
-
Patients' perspective on prostatic artery embolization : A qualitative study
- 2021
-
In: SAGE Open Medicine. - : SAGE Open. - 2050-3121. ; 9, s. 1-6
-
Journal article (peer-reviewed)abstract
- Objectives: The aim was to describe the patients' experience of undergoing prostatic artery embolization.Methods: A retrospective qualitative interview study was undertaken with 15 patients of mean age 73 years who had undergone prostatic artery embolization with a median duration of 210 min at two medium sized hospitals in Sweden. The reasons for conducting prostatic artery embolization were clean intermittent catheterization (n = 4), lower urinary tract symptoms (n = 10) or haematuria (n = 1). Data were collected through individual, semi-structured telephone interviews 1-12 months after treatment and analysed using qualitative content analysis.Results: Four categories with sub-categories were formulated to describe the results: a diverse experience; ability to control the situation; resumption of everyday activities and range of opinions regarding efficacy of outcomes. Overall, the patients described the procedure as painless, easy and interesting and reported that while the procedure can be stressful, a calm atmosphere contributed to achieving a good experience. Limitations on access to reliable information before, during and after the procedure were highlighted as a major issue. Practical ideas for improving patient comfort during the procedure were suggested. Improved communications between treatment staff and patients were also highlighted. Most patients could resume everyday activities, some felt tired and bruising caused unnecessary worry for a few. Regarding functional outcome, some patients described substantial improvement in urine flow while others were satisfied with regaining undisturbed night sleep. Those with less effect were considering transurethral resection of the prostate as a future option. Self-enrolment to the treatment and long median operation time may have influenced the results.Conclusions: From the patients' perspective, prostatic artery embolization is a well-tolerated method for treating benign prostate hyperplacia.
|
|
| 36. |
- Holmstrom, Jesper, et al.
(author)
-
Do we Read what we Share? Analyzing the Click Dynamic of News Articles Shared on Twitter
- 2019
-
In: PROCEEDINGS OF THE 2019 IEEE/ACM INTERNATIONAL CONFERENCE ON ADVANCES IN SOCIAL NETWORKS ANALYSIS AND MINING (ASONAM 2019). - New York, NY, USA : Institute of Electrical and Electronics Engineers (IEEE). - 9781450368681 ; , s. 420-425
-
Conference paper (peer-reviewed)abstract
- News and information spread over social media can have big impact on thoughts, beliefs, and opinions. It is therefore important to understand the sharing dynamics on these forums. However, most studies trying to capture these dynamics rely only on Twitters open APIs to measure how frequently articles are shared/retweeted, and therefore do not capture how many users actually read the articles linked in these tweets. To address this problem, in this paper, we first develop a novel measurement methodology, which combines the Twitter steaming API, the Bitly API, and careful sample rate selection to simultaneously collect and analyze the timeline of both the number of retweets and clicks generated by news article links. Second, we present a temporal analysis of the news cycle based on five-day-long traces (containing both clicks and retweet over time) for the news article links discovered during a seven-day period. Among other things, our analysis highlights differences in the relative timelines observed for clicks and retweets (e.g., retweet data often lags and underestimates the bias towards reading popular links/articles), and helps answer important questions regarding differences in how age-based biases and churn affect how frequently news articles shared on Twitter are accessed over time.
|
|
| 37. |
- Homeyer, Andre, et al.
(author)
-
Automated quantification of steatosis: agreement with stereological point counting
- 2017
-
In: Diagnostic Pathology. - : BIOMED CENTRAL LTD. - 1746-1596. ; 12
-
Journal article (peer-reviewed)abstract
- Background: Steatosis is routinely assessed histologically in clinical practice and research. Automated image analysis can reduce the effort of quantifying steatosis. Since reproducibility is essential for practical use, we have evaluated different analysis methods in terms of their agreement with stereological point counting (SPC) performed by a hepatologist. Methods: The evaluation was based on a large and representative data set of 970 histological images from human patients with different liver diseases. Three of the evaluated methods were built on previously published approaches. One method incorporated a new approach to improve the robustness to image variability. Results: The new method showed the strongest agreement with the expert. At 20x resolution, it reproduced steatosis area fractions with a mean absolute error of 0.011 for absent or mild steatosis and 0.036 for moderate or severe steatosis. At 10x resolution, it was more accurate than and twice as fast as all other methods at 20x resolution. When compared with SPC performed by two additional human observers, its error was substantially lower than one and only slightly above the other observer. Conclusions: The results suggest that the new method can be a suitable automated replacement for SPC. Before further improvements can be verified, it is necessary to thoroughly assess the variability of SPC between human observers.
|
|
| 38. |
- Immerstrand, Charlotte, 1974-, et al.
(author)
-
Altered impedance during pigment aggregation in Xenopus laevis melanophores
- 2003
-
In: Medical and Biological Engineering and Computing. - 0140-0118 .- 1741-0444. ; 41:3, s. 357-364
-
Journal article (peer-reviewed)abstract
- Melanophores are dark-brown pigment cells located in the skin of amphibia, fish and many invertebrates. The skin colour of these organisms is regulated by the translocation of pigment organelles, and the pigment distribution can be altered by external stimuli. The ability to change colour in response to stimuli makes these cells of interest for biosensing applications. It was investigated whether pigment aggregation in Xenopus laevis melanophores can be detected by impedance measurements performed in transparent microvials. The results show that cell attachment, cell spreading and pigment aggregation all resulted in impedance changes, seen particularly at the highest frequency tested (10 kHz). The mechanisms behind the impedance changes were investigated by the addition of latrunculin or melatonin, both of which cause pigment aggregation. The latrunculin-induced aggregation was associated with cell area decrease and filamentous actin (F-actin) breakdown, processes that can influence the impedance. Lack of F-actin breakdown and an increase in cell area during melatonin-induced aggregation suggest that some other intracellular process also contributes to the impedance decrease seen for melatonin. It was shown that impedance measurements reflect not only cell attachment and cell spreading, but also intracellular events.
|
|
| 39. |
- Jager, Edwin, et al.
(author)
-
Biomedical applications of polypyrrole microactuators : from single-cell clinic to microrobots
- 2000
-
In: 1st Annual International, Conference On Microtechnologies in Medicine and Biology. 2000. - : IEEE. - 0780366034 ; , s. 58-61
-
Conference paper (other academic/artistic)abstract
- Microtools that will be useful for the positioning and investigation microstructures must operate relevant environments, such as cell culture media or blood plasma. They must also be comparatively strong, and preferably allow a muscle like mode of movement. This is given by a novel family of actuators based on conjugated polymers (like polypyrrole, PPy). By miniaturising these structures using standard photolithographic techniques, the authors can reduce the size down to 10-micrometer dimensions and build mechanically active microdevices. These can be moved and positioned by applying a potential to dope or undope the PPy. These novel structures are now being developed as a unique microactuator technology, suitable for operation in applications coupled to cell biology and biomedicine
|
|
| 40. |
- Jager, Edwin W.H., et al.
(author)
-
The cell clinic : closable microvials for single cell studies
- 2002
-
In: Biomedical microdevices (Print). - 1387-2176 .- 1572-8781. ; 4:3, s. 177-187
-
Journal article (peer-reviewed)abstract
- We present the development of a cell clinic. This is a micromachined cavity, or microvial, that can be closed with a lid. The lid is activated by two polypyrrole/Au microactuators. Inside the microvials two Au electrodes have been placed in order to perform impedance studies on single or a small number of cells. We report on impedance measurements on Xenopus leavis melanophores. We could measure a change in the impedance upon cell spreading and identify intracellular events such as the aggregation of pigment granules. The electrical data is correlated to optical microscopy.
|
|
| 41. |
- Jakobsson, Ebbe, et al.
(author)
-
Chronic Pain After Groin Hernia Surgery in Women: A Patient-reported Outcome Study Based on Data From the Swedish Hernia Register.
- 2022
-
In: Annals of surgery. - : Lippincott Williams & Wilkins. - 1528-1140 .- 0003-4932. ; 275:2, s. 213-219
-
Journal article (peer-reviewed)abstract
- The aim of this study was to evaluate chronic pain 1 year after surgery, and risk factors for chronic pain after groin hernia repair in women.Groin hernia surgery in women is less frequently studied than in men. Chronic pain is common after groin hernia surgery and remains an important area with room for improvement. Previous studies are small or inconclusive. Guidelines recommend timely repair of all female groin hernias.From the Swedish Hernia Register 4021 female and 37,542 male patients operated between September 1, 2012 and August 30, 2017 responded to a patient-reported outcome questionnaire (response rate 70.0%) 1 year after primary groin hernia surgery. Multivariable analysis was performed to compare chronic postoperative pain in women with men as a control group, and to evaluate risk factors for chronic pain in women.Among women operated for groin hernia, 18% suffered chronic postoperative pain. The risk for chronic pain was significantly higher for women [odds ratio 1.3 (95% confidence interval 1.16-1.46). Three risk factors for chronic pain in women were found: high body mass index, high American Society of Anesthesiologists classification, and femoral hernia. No differences in chronic pain in women were seen when comparing surgical methods or emergency versus elective surgery.Almost one-fifth of women suffered of chronic pain affecting daily activity after groin hernia repair. Chronic pain was more common for women than men. In view of the high-rate chronic postoperative pain, further research on management strategies in female groin hernia is warranted.
|
|
| 42. |
- Jivén, Karl, et al.
(author)
-
Concept design and environmental analysis of a fuel cell RoPax vessel - Report in the HOPE (Hydrogen fuel cells solutions in shipping in relation to other low carbon options) project
- 2023
-
Reports (other academic/artistic)abstract
- This report includes a ship concept design developed for a RoPax ship (a ferry transporting passengers and goods) with hydrogen fuel cell propulsion for intended operations on the route Frederikshavn (Denmark) to Gothenburg (Sweden). The assessments, performed within the HOPE (Hydrogen fuel cells solutions in shipping in relation to other low carbon options – a Nordic perspective) project, shows that it is technically feasible to build and operate such a ship with existing technology for the studied route between these two Nordic countries. Also, the costs of such a concept are assessed and compared to other fuel options including: battery-electric propulsion, electro-ammonia, electro-methanol, biomass-based methane, or fossil liquefied natural gas (LNG), as well as conventional fossil marine gas oil (MGO).The overall result from the comparative analysis of the estimated costs is that the hydrogen fuel cell ship, when assuming current or near future costs for the technology and the hydrogen, is estimated to be some 25 percent more expensive than a conventional fossil fuelled (MGO) RoPax ship (when including costs for emissions in the EU emission trading scheme). However, the cost developments are uncertain. In the case that fuel cell prices, and hydrogen prices, are decreasing, and todays cost levels of emission allowances in the EU emission trading scheme (ETS) increase, the hydrogen fuel cell ship could possibly be operated at lower total costs compared to the MGO fuelled ship.A cost benefit analysis was also performed, comparing costs linked to the technical implementation of hydrogen fuel cell solutions in shipping (with a private and social perspective) to benefits in terms of reduced external costs linked to lower emissions and potential subsides. The cost benefit assessment also confirms that the investment from a private perspective is not cost effective and that additional subsidies may be needed for investments in fuel cell hydrogen technology to take place. The cost effectiveness from a social perspective is strongly dependent on values of highly uncertain parameters.The impacts of emissions of hydrogen as fuel in a Nordic context were assessed for deployment scenarios for hydrogen and fuel cell solutions in Nordic shipping. There is a considerable potential for emission reductions both in terms of CO2, nitrogen oxides (NOX), sulphur dioxide (SO2) and particulate matter (PM) linked to the implementation of hydrogen and fuel cells in Nordic shipping, particularly in the RoPax segment, representing 30% of total CO2 emissions in 2018. Considering the relatively long lifetime of vessels, investments must be made soon to enable a hydrogen powered shipping fleet in the near future. Since it is currently not economically viable with hydrogen and fuel cells vessels there is need for subsidies and investments in pilots to develop solutions and speed up the process.
|
|
| 43. |
|
|
| 44. |
- Kost, Henning, et al.
(author)
-
Training nuclei detection algorithms with simple annotations
- 2017
-
In: Journal of Pathology Informatics. - : Elsevier BV. - 2229-5089 .- 2153-3539. ; 8:1
-
Journal article (peer-reviewed)abstract
- Background: Generating good training datasets is essential for machine learning-based nuclei detection methods. However, creating exhaustive nuclei contour annotations, to derive optimal training data from, is often infeasible. Methods: We compared different approaches for training nuclei detection methods solely based on nucleus center markers. Such markers contain less accurate information, especially with regard to nuclear boundaries, but can be produced much easier and in greater quantities. The approaches use different automated sample extraction methods to derive image positions and class labels from nucleus center markers. In addition, the approaches use different automated sample selection methods to improve the detection quality of the classification algorithm and reduce the run time of the training process. We evaluated the approaches based on a previously published generic nuclei detection algorithm and a set of Ki-67-stained breast cancer images. Results: A Voronoi tessellation-based sample extraction method produced the best performing training sets. However, subsampling of the extracted training samples was crucial. Even simple class balancing improved the detection quality considerably. The incorporation of active learning led to a further increase in detection quality. Conclusions: With appropriate sample extraction and selection methods, nuclei detection algorithms trained on the basis of simple center marker annotations can produce comparable quality to algorithms trained on conventionally created training sets.
|
|
| 45. |
- Källén, Hanna, et al.
(author)
-
Towards Grading Gleason Score using Generically Trained Deep convolutional Neural Networks
- 2016
-
In: 2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI). - : Institute of Electrical and Electronics Engineers (IEEE). - 9781479923496 - 9781479923502 ; 2016-June, s. 1163-1167
-
Conference paper (peer-reviewed)abstract
- We developed an automatic algorithm with the purpose to assist pathologists to report Gleason score on malignant prostatic adenocarcinoma specimen. In order to detect and classify the cancerous tissue, a deep convolutional neural network that had been pre-trained on a large set of photographic images was used. A specific aim was to support intuitive interaction with the result, to let pathologists adjust and correct the output. Therefore, we have designed an algorithm that makes a spatial classification of the whole slide into the same growth patterns as pathologists do. The 22-layer network was cut at an earlier layer and the output from that layer was used to train both a random forest classifier and a support vector machines classifier. At a specific layer a small patch of the image was used to calculate a feature vector and an image is represented by a number of those vectors. We have classified both the individual patches and the entire images. The classification results were compared for different scales of the images and feature vectors from two different layers from the network. Testing was made on a dataset consisting of 213 images, all containing a single class, benign tissue or Gleason score 3-5. Using 10-fold cross validation the accuracy per patch was 81 %. For whole images, the accuracy was increased to 89 %.
|
|
| 46. |
- Lind, Ylva, 1954-, et al.
(author)
-
Stability of fatty acid composition in seal blubber during long-term storage
- 2012
-
In: Marine Ecology Progress Series. - : Inter-Research Science Center. - 0171-8630 .- 1616-1599. ; 461, s. 283-291
-
Journal article (peer-reviewed)abstract
- This study was performed to evaluate the stability of the fatty acid (FA) composition of blubber from Baltic grey seals Halichoerus grypus archived at −25°C in the Swedish Environmental Specimen Bank (SESB). Possible alterations of FA compositions with storage time and temperature were evaluated. Blubber from 5 seals was kept at +2°C and at −20°C and sampled for up to 6 mo and 33 mo, respectively. Furthermore, FA profile stability was evaluated in blubber stored in the SESB for 4 and 6 yr. This was done by re-sampling and re-analyzing blubber samples from SESB. In both parts of the study, a principal component analysis was performed on 48 FAs comprising 98 to 99% of the total FAs in blubber of Baltic grey seals. We found no indication of a critically altered FA composition, neither in blubber stored at +2°C for 6 mo nor in blubber stored at −20°C for 33 mo. The re-analysis of samples stored in SESB for ~4 to 6 yr only differed for a few FAs in some samples. The most remarkable differences were a slight increase in some long-chain unsaturated FAs (18:2n-6, 20:3n-3, 20:4n-3, 22:4n-3). As an increase in long-chain polyunsaturated FAs due to storage is highly unlikely, we believe that this is probably more due to the sampling technique than to a critically altered FA composition due to storage. Our results suggest that archived seal blubber may be safely used in retrospective analyses of diet using an FA signature analysis technique.
|
|
| 47. |
|
|
| 48. |
- Lundström, Karl
(author)
-
Adipose tissue fatty acids suggest spatial and temporal dietary differences in great cormorants of the Baltic Sea area
- 2021
-
In: Journal of the Marine Biological Association of the United Kingdom. - 0025-3154 .- 1469-7769. ; 101, s. 199-213
-
Journal article (peer-reviewed)abstract
- Increased numbers of great cormorants (Phalacrocorax carbo) in the Baltic Sea may have local impacts on fisheries and salmonid hatcheries. We studied spatial and temporal variability in cormorant diet, and potential consumption of hatchery salmonids, by analysing knee subcutaneous adipose tissue fatty acids (FA) of specimens (N = 77) collected along Swedish and Finnish coasts in different seasons during 2013-2017. The FA profiles of the subspecies sinensis and carbo were similar, with large individual variation. The proportion of C18 polyunsaturated FAs (PUFAs) was the largest in the north, whereas the proportion of C20-22 monounsaturated FAs (MUFAs) increased towards the south, reflecting diminishing freshwater and increasing marine food web characteristics towards the south. As an exception, the C20-22 MUFA percentage was high in sinensis collected in June 2017 from the northern Baltic Sea. The source of C20-22 MUFAs was probably hatchery salmonids, raised on ocean fish hatchery feed and released 10 days before, near the cormorant capture site. The FA profiles of northern and southern cormorants differed from each other both in early and late summer samples, suggesting spatially different diets. The largest individual variation was found in 22:1n-11, characteristic of ocean zooplanktivorous fish, and likely originating from Atlantic wild or Baltic Sea hatchery-reared fish. This study shows that adipose tissue FA profiles can be used as proxies for seabird diet monitoring and indicators of predation on hatchery-reared fish. Obtaining quantitative estimates on the proportions of dietary fish species requires future feeding experiments, allowing calibration between the FA compositions and diet.
|
|
| 49. |
- Lundström, Karl, 1971
(author)
-
Assessment of dietary patterns and prey consumption of marine mammals: Grey seals (Halichoerus grypus) in the Baltic Sea
- 2012
-
Doctoral thesis (other academic/artistic)abstract
- The Baltic Sea has been severely affected by pollution and resource overexploitation during the last centuries. The grey seal (Halichoerus grypus) is a good example of how a species can be affected by such changes. In the early 1900s grey seals were common, but hunting and environmental contaminants caused a rapid decline to the verge of extinction in the 1970s. Since the 1980s the population is increasing. This has intensified the conflicts between seals and fisheries, and resource competition between seals and the fishing industry is a matter of debate. This thesis examines dietary patterns and prey consumption by grey seals collected in the Baltic Sea in 2001-2005. It is the first comprehensive study of the Baltic grey seal diet since the early 1970s. Dietary studies of marine mammals generally suffer from a number of possible biases, both concerning the methodology and how the samples are collected. This thesis applies different methods to increase the accuracy and quantifies the uncertainties of the dietary estimates. Conventional analysis of prey remains in the digestive tracts showed that the diet differed between seals from the Gulf of Bothnia and the Baltic Proper, and also between young-of-the-year animals and older animals. Herring (Clupea harengus) was the main prey in all areas and age groups, followed by sprat (Sprattus sprattus) in the south, and common whitefish (Coregonus lavaretus) in the north. Furthermore, the digestive-tract contents of seals collected from certain fishing gear was different from seals collected away from fishing gear. Size and numerical correction factors were used to compensate for biases introduced by digestive erosion of prey otoliths, and additional prey hard parts, other than otoliths, were used to increase the detection level of prey items. The intake of prey biomass by the Baltic grey seal population was estimated using a bioenergetic model and data on population size and diet composition. On a larger spatial scale, the total fish removal by grey seals was negligible. Nevertheless, the predation by seals can have impact on individual prey species and local fish stocks. Concerns for competition between seals and fisheries were augmented by overlapping length distributions of seal prey and commercial catches. The use of fatty acid signature analysis (FASA), which provides long-term dietary information, irrespectively of identifiable prey remains, to a large extent manifested the results from the conventional analysis. However, the application of FASA indicated different feeding habits between male and female grey seals, which were not found using conventional methodology. Application of FASA on marine top predators relies on the background data of the FA signatures of prey species. Grey seal prey species in the Baltic Sea showed a relatively large overlap in FA composition. The intra-specific variation in some species even exceeded the inter-specific variation, which needs to be considered when applying FASA in ecological assessments of fish predators in the Baltic Sea. This study presents a compilation of techniques applicable to assessments of dietary patterns and ecological roles of marine mammals. The results suggest that a combination of different methods, each with its own unique potential as well as limitations, is advisable. Efforts should be made to develop and refine these methods and use them in combination with additional techniques to advance the understanding of the ecology of grey seals in the Baltic Sea.
|
|
| 50. |
- Lundström, Karl
(author)
-
Diet of seals in the Baltic Sea region: a synthesis of published and new data from 1968 to 2013
- 2019
-
In: ICES Journal of Marine Science. - : Oxford University Press (OUP). - 1054-3139 .- 1095-9289. ; 76, s. 284-297
-
Journal article (peer-reviewed)abstract
- A crucial first step in assessing and managing the role and impacts of predators on their environment is knowledge on their foraging behaviour and diet. Here, we synthesize previously published and newly generated data on the diet of harbour seals, grey seals, and ringed seals in the Baltic Sea region. More than 45 000 otoliths recovered from 3147 samples of scats and digestive tracts were collected throughout all seasons and most Baltic Sea sub-basins from 1968 to 2013. The data revealed a large extent of interspecific, spatial, and seasonal variation in seal diet, implying that caution should be made when extrapolating from one species, area or season, to others. Still, a few fish species, including Atlantic herring, sprat, cod, and sandeels had high occurrence across seal species and locations. The compiled data provide the first overview of seal diet across the entire Baltic Sea region, but also comes with several limitations. Thus, while the data presented here constitutes an important reference for future inference, it also illustrates an urgent need for standardizing methodology across studies on the diet of seals and other aquatic predators.
|
|
