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1.	Albernaz, Daniel, 1984- (författare) Phase change, surface tension and turbulence in real fluids 2016 Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract Sprays are extensively used in industry, especially for fuels in internal combustion and gas turbine engines. An optimal fuel/air mixture prior to combustion is desired for these applications, leading to greater efficiency and minimal levels of emissions. The optimization depends on details regarding the different breakups, evaporation and mixing processes. Besides, one should take into consideration that these different steps depend on physical properties of the gas and fuel, such as density, viscosity, heat conductivity and surface tension.In this thesis the phase change and surface tension of a droplet for different flow conditions are studied by means of numerical simulations.This work is part of a larger effort aiming to developing models for sprays in turbulent flows. We are especially interested in the atomization regime, where the liquid breakup causes the formation of droplet sizes much smaller than the jet diameter. The behavior of these small droplets is important to shed more light on how to achieve the homogeneity of the gas-fuel mixture as well as that it directly contributes to the development of large-eddy simulation (LES) models.The numerical approach is a challenging process as one must take into account the transport of heat, mass and momentum for a multiphase flow. We choose a lattice Boltzmann method (LBM) due to its convenient mesoscopic natureto simulate interfacial flows. A non-ideal equation of state is used to control the phase change according to local thermodynamic properties. We analyze the droplet and surrounding vapor for a hydrocarbon fuel close to the critical point. Under forced convection, the droplet evaporation rate is seen to depend on the vapor temperatureand Reynolds number, where oscillatory flows can be observed. Marangoni forces are also present and drivethe droplet internal circulation once the temperature difference at the droplet surface becomes significant.In isotropic turbulence, the vapor phase shows increasing fluctuations of the thermodynamic variables oncethe fluid approaches the critical point. The droplet dynamics is also investigated under turbulent conditions, where the presence of coherent structures with strong shear layers affects the mass transfer between the liquid-vapor flow, showing also a correlation with the droplet deformation. Here, the surface tension and droplet size play a major role and are analyzed in detail.
2.	de Araujo, Gilderlan T., et al. (författare) Semi-Blind Joint Channel and Symbol Estimation in IRS-Assisted Multiuser MIMO Networks 2022 Ingår i: IEEE Wireless Communications Letters. - : Institute of Electrical and Electronics Engineers (IEEE). - 2162-2337 .- 2162-2345. ; 11:7, s. 1553-1557 Tidskriftsartikel (refereegranskat)abstract Intelligent reflecting surface (IRS) is a promising technology for beyond of the wireless communications. In fully passive IRS-assisted systems, channel estimation is challenging and should be carried out only at the base station or at the terminals since the elements of the IRS are incapable of processing signals. In this letter, we formulate a tensor-based semi-blind receiver that solves the joint channel and symbol estimation problem in an IRS-assisted multi-user multiple-input multiple-output system. The proposed approach relies on a generalized PARATUCK tensor model of the signals reflected by the IRS, based on a two-stage closed-form semi-blind receiver using Khatri-Rao and Kronecker factorizations. Simulation results demonstrate the superior performance of the proposed semi-blind receiver, in terms of the normalized mean squared error and symbol error rate, as well as a lower computational complexity, compared to recently proposed parallel factor analysis-based receivers.
3.	Abe, M, et al. (författare) Immunological equivalence between mouse brain-derived and Vero cell-derived Japanese encephalitis vaccines 2006 Ingår i: Virus research. - : Elsevier BV. - 0168-1702. ; 121:2, s. 152-160 Tidskriftsartikel (refereegranskat)
4.	Abe, O, et al. (författare) Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials 2005 Ingår i: Lancet (London, England). - : Elsevier BV. - 1474-547X. ; 365:9472, s. 1687-1717 Tidskriftsartikel (refereegranskat)
5.	Abe, O, et al. (författare) Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials 2005 Ingår i: The Lancet. - 1474-547X. ; 365:9472, s. 1687-1717 Tidskriftsartikel (refereegranskat)abstract Background Quinquennial overviews (1985-2000) of the randomised trials in early breast cancer have assessed the 5-year and 10-year effects of various systemic adjuvant therapies on breast cancer recurrence and survival. Here, we report the 10-year and 15-year effects. Methods Collaborative meta-analyses were undertaken of 194 unconfounded randomised trials of adjuvant chemotherapy or hormonal therapy that began by 1995. Many trials involved CMF (cyclophosphamide, methotrexate, fluorouracil), anthracycline-based combinations such as FAC (fluorouracil, doxombicin, cyclophosphamide) or FEC (fluorouracil, epirubicin, cyclophosphamide), tamoxifen, or ovarian suppression: none involved taxanes, trastuzumab, raloxifene, or modem aromatase inhibitors. Findings Allocation to about 6 months of anthracycline-based polychemotherapy (eg, with FAC or FEC) reduces the annual breast cancer death rate by about 38% (SE 5) for women younger than 50 years of age when diagnosed and by about 20% (SE 4) for those of age 50-69 years when diagnosed, largely irrespective of the use of tamoxifen and of oestrogen receptor (ER) status, nodal status, or other tumour characteristics. Such regimens are significantly (2p=0 . 0001 for recurrence, 2p<0 . 00001 for breast cancer mortality) more effective than CMF chemotherapy. Few women of age 70 years or older entered these chemotherapy trials. For ER-positive disease only, allocation to about 5 years of adjuvant tamoxifen reduces the annual breast cancer death rate by 31% (SE 3), largely irrespective of the use of chemotherapy and of age (<50, 50-69, &GE; 70 years), progesterone receptor status, or other tumour characteristics. 5 years is significantly (2p<0 . 00001 for recurrence, 2p=0 . 01 for breast cancer mortality) more effective than just 1-2 years of tamoxifen. For ER-positive tumours, the annual breast cancer mortality rates are similar during years 0-4 and 5-14, as are the proportional reductions in them by 5 years of tamoxifen, so the cumulative reduction in mortality is more than twice as big at 15 years as at 5 years after diagnosis. These results combine six meta-analyses: anthracycline-based versus no chemotherapy (8000 women); CMF-based versus no chemotherapy (14 000); anthracycline-based versus CMF-based chemotherapy (14 000); about 5 years of tamoxifen versus none (15 000); about 1-2 years of tamoxifen versus none (33 000); and about 5 years versus 1-2 years of tamoxifen (18 000). Finally, allocation to ovarian ablation or suppression (8000 women) also significantly reduces breast cancer mortality, but appears to do so only in the absence of other systemic treatments. For middle-aged women with ER-positive disease (the commonest type of breast cancer), the breast cancer mortality rate throughout the next 15 years would be approximately halved by 6 months of anthracycline-based chemotherapy (with a combination such as FAC or FEC) followed by 5 years of adjuvant tamoxifen. For, if mortality reductions of 38% (age <50 years) and 20% (age 50-69 years) from such chemotherapy were followed by a further reduction of 31% from tamoxifen in the risks that remain, the final mortality reductions would be 57% and 45%, respectively (and, the trial results could well have been somewhat stronger if there had been full compliance with the allocated treatments). Overall survival would be comparably improved, since these treatments have relatively small effects on mortality from the aggregate of all other causes. Interpretation Some of the widely practicable adjuvant drug treatments that were being tested in the 1980s, which substantially reduced 5-year recurrence rates (but had somewhat less effect on 5-year mortality rates), also substantially reduce 15-year mortality rates. Further improvements in long-term survival could well be available from newer drugs, or better use of older drugs.
6.	Abe, O, et al. (författare) Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials 2005 Ingår i: Lancet (London, England). - 1474-547X. ; 366:9503, s. 2087-2106 Tidskriftsartikel (refereegranskat)
7.	Clarke, Emily L., et al. (författare) Development and Evaluation of a Novel Point-of-Use Quality Assurance Tool for Digital Pathology 2019 Ingår i: Archives of Pathology & Laboratory Medicine. - : COLL AMER PATHOLOGISTS. - 0003-9985 .- 1543-2165. ; 143:10, s. 1246-1255 Tidskriftsartikel (refereegranskat)abstract Context.-Flexible working at diverse or remote sites is a major advantage when reporting using digital pathology, but currently there is no method to validate the clinical diagnostic setting within digital microscopy. Objective.-To develop a preliminary Point-of-Use Quality Assurance (POUQA) tool designed specifically to validate the diagnostic setting for digital microscopy. Design.-We based the POUQA tool on the red, green, and blue (RGB) values of hematoxylin-eosin. The tool used 144 hematoxylin-eosin-colored, 5x5-cm patches with a superimposed random letter with subtly lighter RGB values from the background color, with differing levels of difficulty. We performed an initial evaluation across 3 phases within 2 pathology departments: 1 in the United Kingdom and 1 in Sweden. Results.-In total, 53 experiments were conducted across all phases resulting in 7632 test images viewed in all. Results indicated that the display, the users visual system, and the environment each independently impacted performance. Performance was improved with reduction in natural light and through use of medical-grade displays. Conclusions.-The use of a POUQA tool for digital microscopy is essential to afford flexible working while ensuring patient safety. The color-contrast test provides a standardized method of comparing diagnostic settings for digital microscopy. With further planned development, the color-contrast test may be used to create a "Verified Login" for diagnostic setting validation.
8.	Grip, Elsa (författare) På spaning efter styrmedel : kommunal fysisk planering och hållbarhetsmålet 2013 Licentiatavhandling (övrigt vetenskapligt/konstnärligt)abstract Syftet med denna avhandling är att studera styrmedel för kommunal fysisk planering i riktning mot samhällsmålet hållbar utveckling. Huvudfrågan är: finns styrmedel för detta mål? Svaret är i huvudsak ja, men lagstiftningen gör målet otydligt. Sju praktiska och teoretiska delstudier är genomförda under åren 1993-2009 och har undersökts för att komma åt frågan. De använda och föreslagna styrmedlen identifieras i de olika studierna. De är indelade i påverkande – vilja, kunskap, konkurrens; stödjande – organisation, arbetssätt, uppmuntrande – bidrag och utmärkelser, avskräckande - avgifter och skatter, begränsande – översiktsplan, samt tvingande kommunala styrmedel – detaljplanebestämmelser och avtal, tvingande statliga - lagar, byggregler. Planeringen har påverkats av FN:s miljömål som det formulerades 1992 i Agenda 21 från Riokonferensen. Politiker och tjänstemän aktiverades för lokala miljöfrågor och fann nya stödjande styrmedel, arbetssätt och organisation, för att styra miljöarbete. Förändringar i lagstiftning och arbetssätt sedan dess har inte varit av den omfattning som man förväntat sig i planerarkretsar, vilket framkom i intervjuer. Plan- och bygglagen, PBL, är i sig motstridig och lämnar avvägningar mellan olika intressen och hållbar utveckling åt kommunerna. Därmed skapas otydlighet och hållbarhetsmålet kan tolkas som förhandlingsbart. Ansvarsbegreppet används alltmer i lagstiftningen, medan långsiktigt ansvar ännu inte är ett utvecklat begrepp. Begreppet "berörda" enligt PBL behöver förtydligas för att också omfatta kommande generationer, vilket leder till att dagens syn på demokrati behöver vidgas. Ansvar för kommande generationers livsmiljö ligger diffust på alla. Samhällsbyggets aktörer agerar i olika roller: byggherrar, berörda och regelansvariga. De företräder olika professioner och har olika resurser att utöva makt med: politik, ekonomi, juridik och professionalism. Därmed skapas intressekonflikter som ska lösas av kommunen vid varje fysisk förändring. För detta behöver kommunen själv skapa en egen planpolicy med "lokal byggnadsstadga", som visar kommunens vilja och styrmedel för att svara mot Hållbarhetsmålet. De boende uppfattar sig som berörda i en stadsdel och agerar då i miljöfrågor och kan bidra med kunskap i arbetet för stadsdelsplaner. Den i Tyskland lagstadgade Balanseringsprincipen är ett radikalt styrmedel som här föreslås få stöd i PBL. Balansering gör planeringen fokuserad på naturresurser i linje med miljöbalken och inte inriktad på avvägning mellan särintressen som PBL; makten förskjuts från politik till professionalism. Många frågor kvarstår om hur långt kommuner kan och vill styra miljön, särskilt då styrmedel mot klimatförändring ska utvecklas. Avhandlingen bidrar bland annat med förtydliganden om bredden av styrmedel som skulle kunna utnyttjas i den kommunala fysiska planeringen.
9.	Wallenstein, Sven-Olov (författare) The Beast and the Sovereign : Derrida’s Last Seminar 2009 Ingår i: SITE. - 1650-7894. ; :25, s. 3-4 Tidskriftsartikel (populärvet., debatt m.m.)
10.	Hegen, Harald, et al. (författare) Diagnostic value of kappa free light chain index in patients with primary progressive multiple sclerosis - a multicentre study 2023 Ingår i: FRONTIERS IN IMMUNOLOGY. - 1664-3224. ; 14 Tidskriftsartikel (refereegranskat)abstract BackgroundKappa free light chains (kappa-FLC) in the cerebrospinal fluid (CSF) are an emerging biomarker in multiple sclerosis (MS).ObjectiveTo investigate whether kappa-FLC index has similar diagnostic value in patients with primary progressive multiple sclerosis (PPMS) compared to oligoclonal bands (OCB).MethodsPatients with PPMS were recruited through 11 MS centres across 7 countries. kappa-FLC were measured by immunonephelometry/-turbidimetry. OCB were determined by isoelectric focusing and immunofixation.ResultsA total of 174 patients (mean age of 52 +/- 11 years, 51% males) were included. kappa-FLC index using a cut-off of 6.1 was positive in 161 (93%) and OCB in 153 (88%) patients.Conclusion kappa-FLC index shows similar diagnostic sensitivity than OCB in PPMS.
11.	Graham, C., et al. (författare) Comparison of total annual direct costs among Swedish residents with poorly controlled type 1 diabetes: standard care versus real-time continuous glucose monitoring 2010 Ingår i: Diabetologia. - : Springer Science and Business Media LLC. - 1432-0428 .- 0012-186X. ; 53:Suppl. 1, s. 47-47 Konferensbidrag (refereegranskat)
12.	Manca, R., et al. (författare) Homogeneous backward semi-Markov reward models for insurance contracts 2005 Ingår i: Proceedings of ASMDA 2005 Conference. ; , s. 959-967 Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract Numerical algorithms for eveluation of higher order moments for semi-Markov rewards processes are presented. Results of numerical experiments are given and commented.
13.	Rydén, Henric, et al. (författare) RARE two-point Dixon with dual bandwidths. 2020 Ingår i: Magnetic Resonance in Medicine. - : Wiley. - 0740-3194 .- 1522-2594. ; 84:5, s. 2456-2468 Tidskriftsartikel (refereegranskat)abstract PURPOSE: To investigate the impact of dual readout bandwidths (dBW) in a dual echo fat/water acquisition and describe a dBW-rapid acquisition relaxation enhanced, or turbo spin echo sequence where the concept is used to improve SNR by removing dead times between refocusing pulses and avoiding redundant Chemical-shift encoded.METHODS: Cramér-Rao bounds and Monte Carlo simulations were used to investigate a two-point fat/water model where the difference in bandwidths is incorporated. In vivo images were acquired at 1.5 and 3 T with the dBW-rapid acquisition relaxation enhanced, or turbo spin echo sequence. Typical bandwidth ratios were 1:2. SNR was compared with a single bandwidth sequence under identical scan parameters at 3T.RESULTS: Monte Carlo simulations and Cramér-Rao analysis demonstrate that number of signal averages can be improved with dual bandwidths compared to conventional single bandwidth acquisitions. The dBW-rapid acquisition relaxation enhanced, or turbo spin echo sequence can acquire images with high readout resolutions with well-conditioned sampling. An SNR improvement of 52% was measured, in line with the theoretical gain of 54%.CONCLUSIONS: The proposed dBW-rapid acquisition relaxation enhanced, or turbo spin echo sequence is a highly SNR-efficient two-point rapid acquisition relaxation enhanced, or turbo spin echo sequence without dead times, and can acquire images at higher resolutions than current vendor-supplied alternatives.
14.	Rydén, Henric, et al. (författare) T1 weighted fat/water separated PROPELLER acquired with dual bandwidths. 2018 Ingår i: Magnetic Resonance in Medicine. - : Wiley. - 0740-3194 .- 1522-2594. ; 80:6, s. 2501-2513 Tidskriftsartikel (refereegranskat)abstract PURPOSE: To describe a fat/water separated dual receiver bandwidth (rBW) spin echo PROPELLER sequence that eliminates the dead time associated with single rBW sequences. A nonuniform noise whitening by regularization of the fat/water inverse problem is proposed, to enable dual rBW reconstructions.METHODS: Bipolar, flyback, and dual spin echo sequences were developed. All sequences acquire two echoes with different rBW without dead time. Chemical shift displacement was corrected by performing the fat/water separation in k-space, prior to gridding. The proposed sequences were compared to fat saturation, and single rBW sequences, in terms of SNR and CNR efficiency, using clinically relevant acquisition parameters. The impact of motion was investigated.RESULTS: Chemical shift correction greatly improved the image quality, especially at high resolution acquired with low rBW, and also improved motion estimates. SNR efficiency of the dual spin echo sequence was up to 20% higher than the single rBW acquisition, while CNR efficiency was 50% higher for the bipolar acquisition. Noise whitening was deemed necessary for all dual rBW acquisitions, rendering high image quality with strong and homogenous fat suppression.CONCLUSION: Dual rBW sequences eliminate the dead time present in single rBW sequences, which improves SNR efficiency. In combination with the proposed regularization, this enables highly efficient T1-weighted PROPELLER images without chemical shift displacement.
15.	Allhorn, Maria, et al. (författare) Processing of the lipocalin alpha(1)-microglobulin by hemoglobin induces heme-binding and heme-degradation properties. 2002 Ingår i: Blood. - 1528-0020. ; 99:6, s. 1894-1901 Tidskriftsartikel (refereegranskat)abstract alpha(1)-Microglobulin is a 26-kd protein, widespread in plasma and tissues and well-conserved among vertebrates. alpha(1)-Microglobulin belongs to the lipocalins, a protein superfamily with highly conserved 3-dimensional structures, forming an internal ligand binding pocket. The protein, isolated from urine, has a heterogeneous yellow-brown chromophore bound covalently to amino acid side groups around the entrance of the lipocalin pocket. alpha(1)-Microglobulin is found in blood both in free form and complex-bound to immunoglobulin A (IgA) via a half-cystine residue at position 34. It is shown here that an alpha(1)-microglobulin species, which we name t-alpha(1)-microglobulin (t = truncated), with a free Cys34 thiol group, lacking its C-terminal tetrapeptide, LIPR, and with a more polar environment around the entrance of the lipocalin pocket, is released from IgA-alpha(1)-microglobulin as well as from free alpha(1)-microglobulin when exposed to the cytosolic side of erythrocyte membranes or to purified oxyhemoglobin. The processed t-alpha(1)-microglobulin binds heme and the alpha(1)-microglobulin-heme complex shows a time-dependent spectral rearrangement, suggestive of degradation of heme concomitantly with formation of a heterogeneous chromophore associated with the protein. The processed t-alpha(1)-microglobulin is found in normal and pathologic human urine, indicating that the cleavage process occurs in vivo. The results suggest that alpha(1)-microglobulin is involved in extracellular heme catabolism. (Blood. 2002;99:1894-1901)
16.	Govorov, Igor, et al. (författare) Blood inflammatory and endothelial markers in women with von Willebrand disease 2019 Ingår i: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 14:1 Tidskriftsartikel (refereegranskat)abstract Introduction: VWD-affected females often experience menorrhagia. Periodical fluctuations of the sex steroids during the menstrual cycle cause changes both in the coagulation and immune system. The aim of the current study was to assess the changes in selected inflammatory and endothelial markers in women with VWD during two phases of the menstrual cycle (follicular and luteal) and to compare it with corresponding data from healthy controls.Materials and methods: The study group included 12 VWD-affected females with regular menstrual cycle, with none of them being prescribed hormone treatment. They were not pregnant or breastfeeding. The control group consisted of 102 healthy females, matched for age and BMI.Results: Within the VWD group, endostatin was higher during the follicular phase, compared to the luteal phase, although the difference was not significant (p = 0.062). sICAM-1 and IL-6 were higher in VWD-affected females, compared to the controls, sVCAM-1, cathepsin S and sP-selectin were lower (p<0.003 for all cases). The pattern was constant throughout the menstrual cycle.Conclusions: Higher levels of endostatin during early follicular phase could potentially predispose women with VWD to the development of heavy menstrual bleeding, due to antiangiogenic properties and ability to suppress several coagulation factors. Lower p-selectin levels in VWD group, compared to controls, may also contribute to the bleeding tendency. Changes in other proteins, involved in angiogenesis are hypothetically related to the formation of angiodysplasia—common complication of VWF deficiency. The latter statement requires confirmation in larger studies.
17.	Lindahl, Björn (författare) Decomposition in forest ecosystems: after decades of research still novel findings 2011 Ingår i: Fungal Ecology. - : Elsevier BV. - 1754-5048 .- 1878-0083. ; 4, s. 359-361 Annan publikation (övrigt vetenskapligt/konstnärligt)
18.	Malmberg, Jonas, 1962- (författare) Anmälan av Lotta Lerwall, Könsdiskriminering 2002 Ingår i: Svensk Juristtidning. - 0039-6591. ; , s. 204-211 Recension (övrigt vetenskapligt/konstnärligt)
19.	Cory, Erin (författare) Making home in exile : Everyday practices and belongings in Palestinian refugee camps 2020 Ingår i: Crossings. - : Intellect Ltd.. - 2040-4344 .- 2040-4352. ; 11:2, s. 119-136 Tidskriftsartikel (refereegranskat)abstract Palestinians share a history of exile oriented towards the loss and reclamation of a homeland, often expressed through a shared visual lexicon and mythos. In the context of refugee camps, however, local visual culture and everyday practices demonstrate how Palestinian lives are also grounded in local stories and experiences. How do Palestinian refugees deploy everyday practices to create their home spaces? What can these practices reveal about refugees’ myriad belongings? And, in thinking about these practices, what can be said about how a feeling of home can be articulated in exile, which is at its heart the forced removal/dislocation from home? This article uses a comparative ethnographic analysis of two Palestinian camps in Lebanon to challenge overarching narratives of ‘Palestinianness’ by calling attention to the rich multiplicity of Palestinian refugee identities. In focusing the analysis on everyday practices ‐ specifically street art and walking ‐ by which residents make and experience home in the camps, the article grapples with the seeming contradictions between ‘home’ and ‘exile’ that colour the experiences of not only Palestinians, but also refugees and asylum seekers in other circumstances of protracted uncertainty, as they attempt to migrate and make home in new countries.
20.	Kotowska, M, et al. (författare) A GntR-Like Transcription Factor HypR Regulates Expression of Genes Associated With L-Hydroxyproline Utilization in Streptomyces coelicolor A3(2) 2019 Ingår i: Frontiers in microbiology. - : Frontiers Media SA. - 1664-302X. ; 10, s. 1451- Tidskriftsartikel (refereegranskat)
21.	Shi, Jingwen, et al. (författare) Hemolysis of silica particles : Importance of surface properties and plasma corona 2012 Ingår i: Toxicology Letters. - : Elsevier BV. - 0378-4274 .- 1879-3169. ; 211, s. S203-S203 Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
22.	Dwarapudi, Srinivas, et al. (författare) Development of cold bonded chromite pellets for ferrochrome production in submerged arc furnace 2013 Ingår i: ISIJ International. - : Iron and Steel Institute of Japan. - 0915-1559 .- 1347-5460. ; 53:1, s. 9-17 Tidskriftsartikel (refereegranskat)abstract Pelletizing of Indian chromite ores is more challenging due to their high refractory nature. High Cr/Fe ratio and high MgO content in these ores demand high firing temperatures and longer firing cycles but often result in low strength fired pellets. Aim of this study was to develop cold bonded chromite pellets for smelting in submerged arc furnace (SAF) from chromite fines using suitable binder that induce less gangue into the pellets but cures quickly. Different binders were studied through laboratory pelletizing experiments for their suitability for cold bonding the pellets. As result, a composite binder comprising dextrin and bentonite, was found to be suitable and pellets made from the same were tested for their low and high temperature behavior. Electron and optical micro structural studies with image analysis were carried out to find out the type and amount of phases formed in the chromite pellets during high temperature reduction. High temperature reduction studies revealed that pellets were resistant to disintegration up to 1200°C. Pilot scale arc furnace trials were also carried out to compare the performance of cold bonded pellets (CBPs) with sintered chromite pellets and found that for a constant power input, smelting rate was faster for CBPs than sintered pellets. Loss of Cr to slag was reduced in case of cold bonded pellets usage.
23.	Eriksson, L, et al. (författare) The influence of mammographic density on breast tumor characteristics 2012 Ingår i: Breast cancer research and treatment. - : Springer Science and Business Media LLC. - 1573-7217 .- 0167-6806. ; 134:2, s. 859-866 Tidskriftsartikel (refereegranskat)
24.	Gustafsson, Inga-Britt (författare) Forskarutbildning och forskning i ämnet måltidskunskap 2005 Ingår i: Årerts svenska måltidslitteratur 2005. - Grythyttan : Måltidens hus i Norden. ; , s. 40-41 Bokkapitel (populärvet., debatt m.m.)
25.	Herlitz, Johan, et al. (författare) Diurnal, weekly and seasonal rhythm of out of hospital cardiac arrest in Sweden 2002 Ingår i: Resuscitation. - : Elsevier Ireland Ltd. - 0300-9572 .- 1873-1570. ; 54:2, s. 133-138 Tidskriftsartikel (refereegranskat)abstract AIM: To describe the diurnal, weekly and seasonal rhythm among patients suffering from out of hospital cardiac arrest in Sweden. METHODS: All patients in Sweden between 1990 and 1999 participating in a National Registry covering 65% of all patients suffering from out of hospital cardiac arrest where cardiopulmonary resuscitation (CPR) was attempted. Only patients with a cardiac arrest of a cardiac aetiology and aged > 18 years were included in the survey. RESULTS: 10,868 patients fulfilled inclusion criteria. In terms of the diurnal rhythm, there was a progressive increase in the development of cardiac arrest from 06:00 h, reaching a peak at about 10:00 h. Thereafter, there was a progressive decline until 05:00 h. The diurnal rhythm was more marked among patients aged > 65 years and among patients in whom the arrest occurred outside home. There was a weekly rhythm with an increased incidence of cardiac arrest on Mondays. This was particularly evident among patients aged < 66 years and among men. A cardiac arrest occurred most frequently in January and December. This was particularly observed in the large cities. CONCLUSION: We found that out of hospital cardiac arrest of a cardiac etiology has a diurnal, weekly and seasonal rhythm occurring most frequently in the morning hours, on Mondays and in December and January. Age, sex and place of arrest influence these rhythms.
26.	Kotowska, Dorota, et al. (författare) Evaluating Google Street View for tracking invasive alien plants along roads 2021 Ingår i: Ecological Indicators. - : Elsevier BV. - 1470-160X .- 1872-7034. ; 121 Tidskriftsartikel (refereegranskat)abstract Invasive alien plants are considered a major driver of global biodiversity loss. Therefore, there is a huge demand of spatial and temporal data on their distribution for investigating possible drivers of species invasions and for predictions of future distributions. We use Google Street View imagery (GSV) as a new source of spatial and temporal data. GSV provides millions of panoramic views along road networks worldwide allowing for the identification of many plant species, including invasive ones. Thus, GSV has a great potential to support ecological research in documenting species distribution, but reliable validation of its precision and accuracy is lacking. Here, we describe and evaluate an approach using GSV to visually track the spread of invasive alien plants, the North American goldenrods (Solidago canadensis and S. gigantea) occurring abundantly along road network in Poland (Central Europe). We determined presence/absence of the species along 160 randomly selected transects of a length of 500 m by visual inspection of GSV images and compared it with field surveys at the same transects. We show that the occurrence of goldenrods in GSV is a reliable predictor of their occurrence in the wild. Sampling parameters, like road width, season when GSV pictures were taken and number of months elapsed since taking the GSV pictures, did not change the correlation between outputs of the two methods (GSV and field sampling). Furthermore, both the occurrence of goldenrods observed in the field and their occurrence in GSV have similar relations to habitat characteristics investigated (the same direction of relationship and similar effect size). We suggest Google Street View images may be an additional tool to be used in the detection and tracking of the spread of invasive alien plants along roadsides. The approach may be useful in assessing temporal changes in roadside vegetation and managing problematic plant species across large spatial scales and may contribute to the further development of more efficient sampling methods in ecological studies.
27.	Mancarella, Francesco, et al. (författare) Josephson coupling between superconducting islands on single- and bi-layer graphene 2016 Ingår i: Superconductors Science and Technology. - : Institute of Physics Publishing (IOPP). - 0953-2048 .- 1361-6668. ; 29:5 Tidskriftsartikel (refereegranskat)abstract We study the Josephson coupling of superconducting (SC) islands through the surface of single-layer graphene (SLG) and bilayer graphene (BLG) in the long-junction regime, as a function of the distance between the grains, temperature, chemical potential and external (transverse) gate-voltage. For SLG, we provide a comparison with existing literature. The proximity effect is analyzed through a Matsubara Green's function approach. This represents the first step in a discussion of the conditions for the onset of a granular superconductivity within the film, made possible by Josephson currents flowing between superconductors. To ensure phase coherence over the 2D sample, a random spatial distribution can be assumed for the SC islands on the SLG sheet (or intercalating the BLG sheets). The tunable gate-voltage-induced band gap of BLG affects the asymptotic decay of the Josephson coupling-distance characteristic for each pair of SC islands in the sample, which results in a qualitatively strong field dependence of the relation between Berezinskii-Kosterlitz-Thouless transition critical temperature and gate voltage.
28.	Pielaszkiewicz, Jolanta Maria (författare) Contributions to High–Dimensional Analysis under Kolmogorov Condition 2015 Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract This thesis is about high–dimensional problems considered under the so{called Kolmogorov condition. Hence, we consider research questions related to random matrices with p rows (corresponding to the parameters) and n columns (corresponding to the sample size), where p > n, assuming that the ratio converges when the number of parameters and the sample size increase.We focus on the eigenvalue distribution of the considered matrices, since it is a well–known information–carrying object. The spectral distribution with compact support is fully characterized by its moments, i.e., by the normalized expectation of the trace of powers of the matrices. Moreover, such an expectation can be seen as a free moment in the non–commutative space of random matrices of size p x p equipped with the functional . Here, the connections with free probability theory arise. In the relation to that eld we investigate the closed form of the asymptotic spectral distribution for the sum of the quadratic forms. Moreover, we put a free cumulant–moment relation formula that is based on the summation over partitions of the number. This formula is an alternative to the free cumulant{moment relation given through non{crossing partitions ofthe set.Furthermore, we investigate the normalized and derive, using the dierentiation with respect to some symmetric matrix, a recursive formula for that expectation. That allows us to re–establish moments of the Marcenko–Pastur distribution, and hence the recursive relation for the Catalan numbers.In this thesis we also prove that the , where , is a consistent estimator of the . We consider,where , which is proven to be normally distributed. Moreover, we propose, based on these random variables, a test for the identity of the covariance matrix using a goodness{of{t approach. The test performs very well regarding the power of the test compared to some presented alternatives for both the high–dimensional data (p > n) and the multivariate data (p ≤ n).
29.	Rydén, Göran (författare) Den industriella revolutionen i Norden - Gradvis utveckling eller ett sent genombrott? 1997 Ingår i: La Scandinavie. - : Editions Artis-Historia, Brussels. - 2873911115 ; , s. 289 s.- Bokkapitel (refereegranskat)
30.	Rydén, Göran (författare) Descriptions of Technology and Technological Change in the Age of Linnaeus 2007 Konferensbidrag (populärvet., debatt m.m.)
31.	Rydén, Göran, 1959- (författare) Transnational Cultures of Expertise: Circulating State-Related Knowledge in the 18th and 19th Centuries ed. by Lothar Schilling and Jacob Vogel (review) 2020 Ingår i: Technology and culture. - 0040-165X .- 1097-3729. ; 61:4, s. 1242-1243 Recension (övrigt vetenskapligt/konstnärligt)
32.	Strack, Kurt, et al. (författare) CSEM fluid monitoring methodology using real data examples 2022 Ingår i: Second International Meeting for Applied Geoscience & Energy. - : Society of Exploration Geophysicists. ; , s. 677-681 Konferensbidrag (refereegranskat)
33.	Tack, LJW, et al. (författare) Management of Gonads in Adults with Androgen Insensitivity: An International Survey 2018 Ingår i: Hormone research in paediatrics. - : S. Karger AG. - 1663-2826 .- 1663-2818. ; 90:4, s. 236-246 Tidskriftsartikel (refereegranskat)abstract <b><i>Background:</i></b> Complete and partial androgen insensitivity syndrome (CAIS, PAIS) are associated with an increased risk of gonadal germ cell cancer (GGCC). Recent guidelines recommend gonadectomy in women with CAIS in late adolescence. Nevertheless, many adult women prefer to retain their gonads. <b><i>Aims:</i></b> This study aims to explore attitudes towards gonadectomy in AIS in centres around the world, estimate the proportion of adults with retained gonads and/or who developed GGCC, and explore reasons for declining gonadectomy. <b><i>Methods:</i></b> A survey was performed among health care professionals who use the International DSD Registry (I-DSD). <b><i>Results:</i></b> Data were provided from 22 centres in 16 countries on 166 women (CAIS) and 26 men (PAIS). In CAIS, gonadectomy was recommended in early adulthood in 67% of centres; 19/166 (11.4%) women refused gonadectomy. Among 142 women who had gonadectomy, evidence of germ cell neoplasm in situ (GCNIS), the precursor of GGCC, was reported in 2 (1.4%) out of 8 from whom pathology results were formally provided. Nine out of 26 men with PAIS (34.6%) had retained gonads; 11% of centres recommended routine gonadectomy in PAIS. <b><i>Conclusion:</i></b> Although development of GGCC seems rare, gonadectomy after puberty is broadly recommended in CAIS; in PAIS this is more variable. Overall, our data reflect the need for evidence-based guidelines regarding prophylactic gonadectomy in AIS.
34.	Visibile, Alberto, 1989, et al. (författare) High temperature oxidation of inconel 939 produced by additive manufacturing 2024 Ingår i: Corrosion Science. - 0010-938X. ; 233 Tidskriftsartikel (refereegranskat)abstract High temperature oxidation of additively manufactured (Laser-powder bed fusion) IN939 (AM IN939) was studied at 900°C in dry air for 168 hours. AM IN939 cut parallel/perpendicular to the building direction, including conventionally manufactured (CM) IN939 were exposed to assess the influence of AM microstructure and its inherent anisotropy on oxidation properties. Microstructural anisotropy had no significant impact on oxidation properties. AM and CM IN939 exhibited nearly identical mass gains, yet local spallation was observed in the former. Further investigation involved oxidation of heat-treated AM IN939, revealing improved adhesion, possibly due to transformation of fine dendritic/cellular structure into coarse equiaxed grains.
35.	Zander, Ulf (författare) Tre mäktiga kvinnor i blixtbelysning 2023 Ingår i: Populär Historia. - 1102-0822. ; 32:13, s. 68-68 Recension (populärvet., debatt m.m.)abstract
36.	Badinlou, F, et al. (författare) The Persian version of the psychological flexibility in sport scale: a psychometric study 2022 Ingår i: BMC psychology. - 2050-7283. ; 10:1, s. 250- Tidskriftsartikel (refereegranskat)
37.	Bibic, Adnan, et al. (författare) Measurement of vascular water transport in human subjects using time-resolved pulsed arterial spin labelling. 2015 Ingår i: NMR in Biomedicine. - : Wiley. - 0952-3480. ; 28:8, s. 1059-1068 Tidskriftsartikel (refereegranskat)abstract Most approaches to arterial spin labelling (ASL) data analysis aim to provide a quantitative measure of the cerebral blood flow (CBF). This study, however, focuses on the measurement of the transfer time of blood water through the capillaries to the parenchyma (referred to as the capillary transfer time, CTT) as an alternative parameter to characterise the haemodynamics of the system. The method employed is based on a non-compartmental model, and no measurements need to be added to a common time-resolved ASL experiment. Brownian motion of labelled spins in a potential was described by a one-dimensional general Langevin equation as the starting point, and as a Fokker-Planck differential equation for the averaged distribution of labelled spins at the end point, which takes into account the effects of flow and dispersion of labelled water by the pseudorandom nature of the microvasculature and the transcapillary permeability. Multi-inversion time (multi-TI) ASL data were acquired in 14 healthy subjects on two occasions in a test-retest design, using a pulsed ASL sequence and three-dimensional gradient and spin echo (3D-GRASE) readout. Based on an error analysis to predict the size of a region of interest (ROI) required to obtain reasonably precise parameter estimates, data were analysed in two relatively large ROIs, i.e. the occipital lobe (OC) and the insular cortex (IC). The average values of CTT in OC were 260 ± 60 ms in the first experiment and 270 ± 60 ms in the second experiment. The corresponding IC values were 460 ± 130 ms and 420 ± 139 ms, respectively. Information related to the water transfer time may be important for diagnostics and follow-up of cerebral conditions or diseases characterised by a disrupted blood-brain barrier or disturbed capillary blood flow. Copyright © 2015 John Wiley & Sons, Ltd.
38.	Dahlman-Hoglund, A., et al. (författare) Endotoxin in Aerosol Particles from Metalworking Fluids Measured with a Sioutas Cascade Impactor 2022 Ingår i: Annals of Work Exposures and Health. - : Oxford University Press (OUP). - 2398-7308 .- 2398-7316. ; 66:2, s. 260-268 Tidskriftsartikel (refereegranskat)abstract Objectives The aim of this study was to characterize personal occupational exposure to endotoxin in size-separated airborne particles of MWF aerosol, using a Sioutas cascade impactor (SCI). Methods Exposure to inhalable fractions of MWF aerosol and endotoxin was measured by personal sampling of 52 individuals over an 8-h work shift using a PAS-6 sampler in parallel with a SCI (<0.25, 0.25-0.5, 0.5-1.0, 1.0-2.5, and 2.5-10 mu m). Aerosol mass concentration was measured for each worker with a real-time instrument (DataRAM) during a full shift. Samples of MWF were collected from the machines and central tanks during the work shift. Results A total of 117 measurements of inhalable MWF aerosols were made among 52 workers. The geometric mean of inhalable MWF aerosol was 0.16 mg m(-3) air. The geometric mean of endotoxin concentration on the inhalable sampler was 0.15 EU m(-3). Airborne endotoxin was found on all size fractions from the impactor, with the major part seen in the fraction (2.5-10 mu m). There was a correlation between the inhalable fraction of endotoxin measured by the PAS-6 sampler and on the SCI sampler (2.5-10 mu m), estimated to be 0.51 for all samples (P < 0.0001). The concentration of endotoxin varied between the MWFs, as did the proportion of Gram-negative bacteria among the culturable bacteria (>80% in one MWF and <1.5% in the other three). Conclusions The personal exposure to inhalable fractions of endotoxin contained in the MWF aerosol were low, where most of the endotoxin were found in fraction (2.5-10 mu m), measured by SCI. There are differences between factories and MWF systems regarding the distribution of endotoxin and so results from one context should not be generalized to other plants and systems. Compressed air was used for less than 10 min shift(-1). The mixed-effect model showed that working with open machines and grinding as cutting task were important determinants of exposure to inhalable aerosol. It is important to keep occupational exposure to aerosols low with the help of good ventilation systems, enclosed machines, and organization of work.
39.	Dolles, Harald, et al. (författare) Outlook : sport and business - a future research agenda 2013 Ingår i: Handbook of research on sport and business. - Cheltenham : Edward Elgar Publishing. - 9781849800051 ; , s. 548-563 Bokkapitel (refereegranskat)
40.	Dolles, Harald, 1961, et al. (författare) Outlook: Sport and Business – A Future Research Agenda 2013 Ingår i: Handbook of Research on Sport and Business. - Cheltenham, UK : Edward Elgar. - 9781849800051 ; , s. 548-563 Bokkapitel (refereegranskat)abstract We conclude and emphasize that sport management researchers must devote time to understand the mega-shifts that increasingly appear to characterise the changing nature of sport and its environment. The growth of social networking, for instance, is something that has taken many organisations aback. Diminishing gender differences in sporting achievements and the growing interest in women’s sport (just to mention Nadeshiko Japan: After becoming world champions in football in Germany in 2010 the Nadeshiko Japan is the most successful Asian team in women’s football and is now attracting crowds that could not previously have been dreamt of for female football in Japan) might be another mega-trend. Missing important product or management innovations might be one of the reasons for losing the competitive edge in sport. While the expected positive effects of innovation strategies are well documented and supported empirically within industry and services research in the field of innovation and sports is still very limited; just consider the development and implementation of enhanced sports products (like the new football for the Football World Cup in Germany, or performance-aiding swim suits as used during the Beijing Olympic Games and the Rome World Championships or advanced swimming goggles to allow for 180-degree peripheral vision underwater), aspects of the ‘dark-side’ of sports (like using drugs and innovative ways of drug-testing), the development of sporting facilities (like wave-crushing lane ropes to diminish and deflect waves in the pool, which helps swimmers to swim faster as they do not need to battle the waves), or the development of new forms of sports (like long-boarding, kite-surfing or T20 cricket). Being able to predict such developments, identifying how sport organizsations should respond, and the way in which technology can help to accentuate and enhance the fundamental features of sport can become a route through which researchers are able to make significant empirical and theoretical contributions to the advancement of research on sport and business.
41.	Edgar, Boo, 1948, et al. (författare) Increasing the utility of university based bioscience research - trends in Norway and Sweden 2005 Ingår i: BioForum Europe 5/2005. Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract A European strategy for life science and biotechnology produced by the commission in 2002 and 2003 preceded national bioscience strategies published recently in Norway and Sweden. This article summarizes these strategies and compares them with some current trends and visions in the area of utilizing bioscience research in the two countries.In the European strategy , bioscience was placed in the frontline being seen as the next wave in the knowledge economy after information technology. Key elements in the strategy are:- Developing bioscience education- Improving the intellectual property system - Facilitating the access to capital - Networking for the stakeholders- Increase the proactive role for the public authorities - Responding to a global challenge - Implement the strategy coherently and further develop the strategy In the 19th annual provocative report "Beyond borders"[2], Ernst & Young describes the situation as not so favorable in Europe as compared to the rest of the world.In summary the bioscience industry in Europe is considered to recover and is now better positioned to move forward - but remains restricted by fundamental European issues.As can be seen in figure 1, the European number of bioscience companies is at least as high as in the US. However, there are significant differences in both size and maturity. The biotech industry is generally becoming more global and more competitive. In terms of financial figures, the industry is dominated by the activities in the US. However, Canada and Europe are catching up, driven by strong strategies. The major advantages for younger companies are the available market and resources strengths from around the world.Nevertheless, there is a still a concern around valuation and financing, where most capital and early financing is available in the US. The amounts of available funds have according to the Ernst & Young report not grown in Europe for a while. A key concern is still to build sustainable companies around experienced management teams and good products. In Europe more companies are built around a single good product idea rather than a product portfolio. Many such early stage companies are struggling to avoid the much feared "wash-out" by keeping the initially spent cash as low as possible with a non optimal development as a result..
42.	Elingius, Laurentius Ingevaldi, 1640-1687 (författare) Toga Romana in genere delineata. Et consensu ampl. facult. phil. in incluta academia Upsaliensi, sub præsidio ... Laurentii Elingii ... publico doctorum examini submissa ab Olao Toltonio Vesm. Ad diem [17 Decemb.] a. M. DC. LXXXVII. 1687 Doktorsavhandling (övrigt vetenskapligt/konstnärligt)
43.	Gao, Chaobing, et al. (författare) Up-regulated expression of Dicer reveals poor prognosis in laryngeal squamous cell carcinoma 2014 Ingår i: Acta Oto-Laryngologica. - : Informa UK Limited. - 0001-6489 .- 1651-2251. ; 134:9, s. 959-963 Tidskriftsartikel (refereegranskat)abstract Conclusions: Increased expression of Dicer may be a prognostic biomarker for patients with laryngeal squamous cell carcinoma (LSCC). Objectives: Recent studies have shown that many microRNAs (miRNAs) play an important role in the development and progression of human cancers. Dicer, one of the most important enzymes of the miRNA machinery, performs the final step of biogenesis of miRNAs. This study aimed to investigate the impact of Dicer expression on patient survival in human LSCC. Methods: We detected the expression of Dicer in larynx tissue specimens from 76 LSCC samples and 26 polyps by immunohistochemistry. The clinicopathological and prognostic significance of Dicer expression was investigated in LSCC. Results: Our data showed that the expression of Dicer was significantly higher in the LSCC than in the polyp tissue specimens. Moreover, the expression level of Dicer was significantly associated with the pTNM stage and tumor lymph node metastasis. Kaplan-Meier survival analyses revealed a strong association between tumor Dicer expression and the survival of the patients with LSCC.
44.	Gao, C. X., et al. (författare) Exploration of multiple Sortase A protein conformations in virtual screening 2016 Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 6:20413 Tidskriftsartikel (refereegranskat)abstract Methicillin resistant Staphylococcus aureus (MRSA) has become a major health concern which has brought about an urgent need for new therapeutic agents. As the S. aureus Sortase A (SrtA) enzyme contributes to the adherence of the bacteria to the host cells, inhibition thereof by small molecules could be employed as potential antivirulence agents, also towards resistant strains. Albeit several virtual docking SrtA campaigns have been reported, no strongly inhibitatory non-covalent binders have as yet emerged therefrom. In order to better understand the binding modes of small molecules, and the effect of different receptor structures employed in the screening, we herein report on an exploratory study employing 10 known binders and 500 decoys on 100 SrtA structures generated from regular or steered molecular dynamics simulations on four different SrtA crystal/NMR structures. The results suggest a correlation between the protein structural flexibility and the virtual screening performance, and confirm the noted immobilization of the beta 6/beta 7 loop upon substrate binding. The NMR structures reported appear to perform slightly better than the Xray-crystal structures, but the binding modes fluctuate tremendously, and it might be suspected that the catalytic site is not necessarily the preferred site of binding for some of the reported active compounds.
45.	Herlitz, Johan, 1949, et al. (författare) Cause of death during 13 years after coronary artery bypass grafting with emphasis on cardiac death 2004 Ingår i: Scand Cardiovasc J. - : Informa UK Limited. - 1401-7431 .- 1651-2006. ; 38:5, s. 283-6 Tidskriftsartikel (refereegranskat)abstract OBJECTIVE: To describe the cause of death in the long term after coronary artery bypass grafting (CABG) with particular emphasis on cardiac death. PATIENTS AND SETTING: All the patients in western Sweden without simultaneous valve surgery and without previous CABG who underwent CABG in 1988-1991 in Goteborg, Sweden. DESIGN: Prospective, observational study for 10.6-13.6 years (i.e. until the end of 2001). Various factors contributing to death were described, with the emphasis on cardiac death. RESULTS: In all, 2000 patients were included in the survey. The all-cause mortality rate was 39%. Fifty-eight per cent of all deaths were judged as cardiac deaths. The most frequent cause of death was heart failure (65% among patients who died within 30 days after CABG and 36% among those who died >30 days after CABG). The second most common cause of death was myocardial infarction (56 and 29%, respectively), followed by cancer (0 and 24%, respectively), stroke (21 and 18%, respectively) and infection (8 and 11%, respectively). CONCLUSION: The factors most commonly contributing to death in the long term after CABG were, in order of frequency, heart failure, myocardial infarction, cancer, stroke and infection.
46.	Hiyoshi, Ayako, 1972-, et al. (författare) Trends in health and health inequality during the Japanese economic stagnation : Implications for a healthy planet 2023 Ingår i: SSM - Population Health. - : Elsevier. - 2352-8273. ; 22 Tidskriftsartikel (refereegranskat)abstract INTRODUCTION: Human health and wellbeing may depend on economic growth, the implication being that policymakers need to choose between population health and the health of ecosystems. Over two decades of low economic growth, Japan's life expectancy grew. Here we assess the temporal changes of subjective health and health inequality during the long-term low economic growth period.METHODS: Eight triennial cross-sectional nationally representative surveys in Japan over the period of economic stagnation from 1992 to 2013 were used (n = 625,262). Health is defined positively as wellbeing, and negatively as poor health, based on self-rated health. We used Slope and Relative Indices of Inequality to model inequalities in self-rated health based on household income. Temporal changes in health and health inequalities over time were examined separately for children/adolescents, working-age adults, young-old and old-old.RESULTS: At the end of the period of economic stagnation (2013), compared to the beginning (1992), the overall prevalence of wellbeing declined slightly in all age groups. However, poor health was stable or declined in the young-old and old-old, respectively, and increased only in working-age adults (Prevalence ratio: 1.14, 95% CI 1.08, 1.20, <0.001). Over time, inequality in wellbeing and poor self-rated health were observed in adults but less consistently for children, but the inequalities did not widen in any age group between the start and end of the stagnation period.CONCLUSIONS: Although this study was a case study of one country, Japan, and inference to other countries cannot be made with certainty, the findings provide evidence that low economic growth over two decades did not inevitably translate to unfavourable population health. Japanese health inequalities according to income were stable during the study period. Therefore, this study highlighted the possibility that for high-income countries, low economic growth may be compatible with good population health.
47.	Hjalmar, V, et al. (författare) Trisomy 12 and lymphoplasmacytoid lymphomas. 1997 Ingår i: BLOOD. - 0006-4971. ; 90:10, s. 3901-3901 Konferensbidrag (övrigt vetenskapligt/konstnärligt)
48.	Hjalmars, Ulf (författare) Epidemiological studies including new methods for cluster analysis of acute childhood leukaemia and brain tumours in Sweden 1998 Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract Background: The aetiology in childhood cancer is essentially unknown. Epidemiological investigations as to whether the incidence rates have changed for paediatric cancers or whether clustering of cases occur may give clues to possible causal factors. One of the main purposes of the present work was to develop improved methods for spatial epidemiological investigations, especially cluster analyses and apply the methods evolved to the two most common forms of childhood malignancies: leukaemia and brain tumors. Material and methods: Population-based materials of all cases of acute childhood leukaemia during the period 1973 to 1994 and registered brain tumours during the period 1973 to 1992 among children under 16 years of age were analysed. A geographical information system (GIS) was utilised in the management of spatially referenced data on patients and population. Analyses of geographical clustering in space, space-time and of space-time interaction were conducted by essentially new statistical methods, evolved in the work, namely a spatial scan statistic and a modified Knox test. For the brain tumours, analyses of temporal trends were performed by a logistic regression procedure. Results: No statistically significant: geographically localised clusters of childhood leukaemia in Sweden were detected in space or in space-time. Statistically significant space-time interaction was found for acute lymphoblastic leukaemia (ALL) in the analyses using the modified Knox test statistic (p=0.01). Incidence rates in population centres, constituting 1.3% of Sweden's land area and approximately 80% of the population, compared to the rest of Sweden showed a statistically significant excess of (ALL), (OR 1.68, 95% CI 1.44-1.95) but not of acute non- lymphoblastic leukaemia (ANLL), (OR 1.13, 95% Cl 0.98-1.32). There was no statistically significant increase in the incidence of acute childhood leukaemia in areas contaminated due to the Chernobyl reactor accident. Statistically significant increasing time trends were observed for the group of childhood malignant brain tumours as a whole (p = 0.0001) largely caused by an increase for the astrocytoma subgroup (p = 0.0001). The increase of astrocytoma rates was significantly larger for girls than for boys (p = 0.021). Conclusions: No geographically localised clusters were found for acute childhood leukaemia and childhood brain tumours. The space-time interaction found for ALL indicates that environmental factors may be of importance to the aetiology of childhood ALL. No increased risk for ALL or ANLL was found after the heavy fallout in parts of Sweden after the Chernobyl reactor accident. The statistically significant increase of brain tumours, notably astrocytomas in girls, indicates the possible importance of some environmental factors to the aetiology. Within the project important improvements to the methodology of spatial analyses have been developed, which may possibly set a new standard for investigations of disease clusters and clustering.
49.	Janney, R, et al. (författare) Computer calculations of the photresponse of a diffused silicon pn junction using the Gummel de Mari algorithm 1978 Ingår i: Solid-State Electronics. - 0038-1101 .- 1879-2405. ; 21, s. 796- Tidskriftsartikel (refereegranskat)
50.	Jarmander, Johan, 1983-, et al. (författare) A dual tag system for facilitated detection of surface expressed proteins in Escherichia coli 2012 Ingår i: Microbial Cell Factories. - : Springer Science and Business Media LLC. - 1475-2859. ; 11 Tidskriftsartikel (refereegranskat)abstract Background: The discovery of the autotransporter family has provided a mechanism for surface expression of proteins in laboratory strains of Escherichia coli. We have previously reported the use of the AIDA-I autotransport system to express the Salmonella enterica serovar Enteritidis proteins SefA and H: gm. The SefA protein was successfully exposed to the medium, but the orientation of H:gm in the outer membrane could not be determined due to proteolytic cleavage of the N-terminal detection-tag. The goal of the present work was therefore to construct a vector containing elements that facilitates analysis of surface expression, especially for proteins that are sensitive to proteolysis or otherwise difficult to express. Results: The surface expression system pAIDA1 was created with two detection tags flanking the passenger protein. Successful expression of SefA and H:gm on the surface of E. coli was confirmed with fluorescently labeled antibodies specific for the N-terminal His(6)-tag and the C-terminal Myc-tag. While both tags were detected during SefA expression, only the Myc-tag could be detected for H: gm. The negative signal indicates a proteolytic cleavage of this protein that removes the His(6)-tag facing the medium. Conclusions: Expression levels from pAIDA1 were comparable to or higher than those achieved with the formerly used vector. The presence of the Myc- but not of the His(6)-tag on the cell surface during H:gm expression allowed us to confirm the hypothesis that this fusion protein was present on the surface and oriented towards the cell exterior. Western blot analysis revealed degradation products of the same molecular weight for SefA and H:gm. The size of these fragments suggests that both fusion proteins have been cleaved at a specific site close to the C-terminal end of the passenger. This proteolysis was concluded to take place either in the outer membrane or in the periplasm. Since H:gm was cleaved to a much greater extent then the three times smaller SefA, it is proposed that the longer translocation time for the larger H:gm makes it more susceptible to proteolysis.

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