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Numrering	Referens	Omslagsbild	Hitta
1.	Hansson, Elisabeth, 1955, et al. (författare) Coupled cell networks are target cells of inflammation, which can spread between different body organs and develop into systemic chronic inflammation 2015 Ingår i: Journal of Inflammation-London. - : Springer Science and Business Media LLC. - 1476-9255. ; 12 Forskningsöversikt (refereegranskat)abstract Several organs in the body comprise cells coupled into networks. These cells have in common that they are excitable but do not express action potentials. Furthermore, they are equipped with Ca2+ signaling systems, which can be intercellular and/or extracellular. The transport of small molecules between the cells occurs through gap junctions comprising connexin 43. Examples of cells coupled into networks include astrocytes, keratinocytes, chondrocytes, synovial fibroblasts, osteoblasts, connective tissue cells, cardiac and corneal fibroblasts, myofibroblasts, hepatocytes, and different types of glandular cells. These cells are targets for inflammation, which can be initiated after injury or in disease. If the inflammation reaches the CNS, it develops into neuroinflammation and can be of importance in the development of systemic chronic inflammation, which can manifest as pain and result in changes in the expression and structure of cellular components. Biochemical parameters of importance for cellular functions are described in this review.

Hansson, Elisabeth, 1955, et al. (författare)
Coupled cell networks are target cells of inflammation, which can spread between different body organs and develop into systemic chronic inflammation
2015
Ingår i: Journal of Inflammation-London. - : Springer Science and Business Media LLC. - 1476-9255. ; 12
Forskningsöversikt (refereegranskat)abstract
- Several organs in the body comprise cells coupled into networks. These cells have in common that they are excitable but do not express action potentials. Furthermore, they are equipped with Ca2+ signaling systems, which can be intercellular and/or extracellular. The transport of small molecules between the cells occurs through gap junctions comprising connexin 43. Examples of cells coupled into networks include astrocytes, keratinocytes, chondrocytes, synovial fibroblasts, osteoblasts, connective tissue cells, cardiac and corneal fibroblasts, myofibroblasts, hepatocytes, and different types of glandular cells. These cells are targets for inflammation, which can be initiated after injury or in disease. If the inflammation reaches the CNS, it develops into neuroinflammation and can be of importance in the development of systemic chronic inflammation, which can manifest as pain and result in changes in the expression and structure of cellular components. Biochemical parameters of importance for cellular functions are described in this review.

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