| 51. |
- Dahl, P., et al.
(författare)
-
Densification and properties of zirconia prepared by three different sintering techniques
- 2007
-
Ingår i: Ceramics International. - : Elsevier BV. - 0272-8842 .- 1873-3956. ; 33:8, s. 1603-1610
-
Tidskriftsartikel (refereegranskat)abstract
- Densification of nanocrystalline yttria stabilized zirconia (YSZ) powder with 8 mol% Y2O3, prepared by a glycine/nitrate smoldering combustion method, was investigated by spark plasma sintering, hot pressing and conventional sintering. The spark plasma sintering technique was shown to be superior to the other methods giving dense materials (>= 96%) with uniform morphology at lower temperatures and shorter sintering time. The grain size of the materials was 0.21, 0.37 and 12 mu m after spark plasma sintering, hot pressing and conventional sintering, respectively. Total electrical conductivity of the materials showed no clear correlation with the grain size, but the activation energy for spark plasma sintered materials was slightly higher than for materials prepared by the two other densification methods. The hardness, measured by the Vickers indentation method, was found to be independent on grain size while fracture toughness, derived by the indentation method, was slightly decreasing with increasing grain size.
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| 52. |
- de Vera, Jean Paul, et al.
(författare)
-
EUROX (Europa Explorer): An astrobiology mission concept to the Jovian icy moon Europa.
- 2008
-
Ingår i: Geophysical Research Abstracts. ; 10, EGU2008-A-01483, 2008
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- The discovery of so-called extremophiles indicates how robust life is. That microbial life can resist extreme and harsh environmental conditions as e.g. very high and cold temperatures, desiccation, acidity, salinity and wide ranges of radiation spectra including UV and X-rays, suggests that micro organisms are capable of surviving and maintaining essential living functions, or often thriving, in conditions previously thought impossible. Recently it seems that only liquid water and an energy source are the core prerequisites for the development of life, greatly expanding the range of potential habitats for life both on Earth and in the solar system. In light of these discoveries, the definition of the “Habitable Zone” as the region where liquid water can exist at a planetary surface may need revision. Energy in the form of heat may be found on several volcanic worlds in our solar system, and subsurface liquid water may exist there, too. One likely candidate for such a reserve of water is the jovian icy moon Europa. Imaged by the Voyager and Galileo probes, this icy body appears to have a geologically young outer surface. Spectroscopic studies from Earth have confirmed that the European crust is composed of water ice. Long cracks across its surface may be suggestive of huge ice blocks rafting upon an underlying liquid layer. Darker non ice material also covers much of the surface and is spatially associated with the cracks. Recent modeling suggests that tidal forces imparted upon the moon by Jupiter may cause heating in the depth – raising the possibility of a liquid water ocean beneath Europa’s icy crust. Further on it is supposed that a weak induced magnetic field is present on the moon. This classifies Europa as an object of great scientific interest, warranting investigation for habitability and even the presence of life within the supposed ocean of the moon. The Europa Explorer (EUROX) mission complements other proposed missions to study Europa. EUROX will characterize the habitability potential of Europa, with the aim of understanding whether life could exist there or not. The mission will address the following key questions: (i) existence or non- existence of a liquid ocean beneath the surface, (ii) the nature of the non icy material visible upon the surface cracks, (iii) the physical characteristics of the ice crust, (iv) effects by local radiation on the surface chemistry, (v) the depth of radiation penetration in the ice and probably shielding effects by a magnetic field and (vi) the presence of organic compounds on or in the Europan ice crust. Our proposed mission will operate as a fully European and further on international mission, with the aim of providing the initial information required for later, larger missions to visit Europa. EUROX will involve both remote-sensing and in-situ research. Its mission architecture sees a single space craft deployed to Europa, launched by an Ariane 5. This vehicle will use conventional propulsion and a Venus-Earth-Earth flight path to travel to the jovian system in six years. Upon arrival at Europa, the space craft will commence remote observations of the icy moon, to determine the physical nature of the ice crust, and to investigate the presence of a subsurface liquid ocean. The orbiter will carry two independent vehicles (two penetrators) that will then separate, de-orbit, and penetrate the crust nearby or in the cracks to a depth of several meters. A suite of compact instruments will address the physical and chemical properties of the crust, as well as seeking organic compounds and pre-biotic material in the ice. The use of a laser communication system removes the need for a relay spacecraft in orbit around Jupiter, decreasing overall mission cost. Expected orbiter mission duration is on the order of two months, with each penetrator functioning for approximately 24 hours.
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| 53. |
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| 54. |
- Djane, N K, et al.
(författare)
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Chromium speciation in natural waters using serially connected supported liquid membranes.
- 1999
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Ingår i: Talanta. - 1873-3573. ; 48:5, s. 1121-1132
-
Tidskriftsartikel (refereegranskat)abstract
- A supported liquid membrane (SLM) method for the speciation of chromium has been developed. The method is based on selective extraction and enrichment of anionic Cr(VI) and cationic Cr(III) species in two serially connected SLM units. Methyltricaprylammonium chloride (Aliquat) and di-(2-ethylhexyl) phosphoric acid (DEHPA), respectively were used as the selective extractants in the membrane liquid. Graphite furnace atomic absorption spectrometry (GFAAS) was utilised for final determination. Optimised conditions for the DEHPA membrane were, sample solution at pH 3, acceptor solution 0.1 M HNO(3) and 10% w/w carrier in kerosene. The corresponding values for the Aliquat membrane were pH 7, 0.75 M HNO(3) and 6% w/w carrier in di-n-hexylether. This gave extraction efficiencies for Cr(III) and Cr(VI) of 90 and 40%, respectively. The method was used to measure the concentration of Cr III and Cr VI in surface water from an abandoned tannery site. Storage experiments at different pH showed that preservation at neutral pH gave almost constant values over a period of one month. At acidic pH (pH=3.0) the concentration of Cr(VI) decreased rapidly while the concentration of Cr(III) increased. The detection limit, expressed as three times the standard deviation of enriched blank samples was 0.01 mug l(-1).
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| 55. |
- Ehnhage, A, et al.
(författare)
-
Corrigendum
- 2016
-
Ingår i: Acta oto-laryngologica. - : Informa UK Limited. - 1651-2251 .- 0001-6489. ; 136:9, s. 982-982
-
Tidskriftsartikel (refereegranskat)
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| 56. |
- Ekholm, M, et al.
(författare)
-
Long-term angiotensin-converting enzyme inhibition with ramipril reduces thrombin generation in human hypertension
- 2002
-
Ingår i: Clinical science (London, England : 1979). - : Portland Press Ltd.. - 0143-5221 .- 1470-8736. ; 103:2, s. 151-155
-
Tidskriftsartikel (refereegranskat)abstract
- Antihypertensive treatment reduces the risk of thromboembolic events in hypertension. The aim of this study was to examine the influence of angiotensin-converting enzyme inhibition on blood coagulation in subjects with mild-to-moderate essential hypertension. Fibrinogen, thrombin–antithrombin complex (TAT) and Factor VII were determined in plasma at rest and after a mental stress test following placebo for 6 weeks, or ramipril for 6 weeks or 6 months. Ramipril reduced resting TAT, and tended to reduce fibrinogen; Factor VII remained unchanged. Mental stress increased fibrinogen, but did not alter TAT or Factor VII activity. The reduced thrombin generation in patients taking ramipril may explain in part why angiotensin-converting enzyme inhibitors reduce thromboembolic complications in patients with cardiovascular disease.
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| 57. |
- Engström, Gunnar, et al.
(författare)
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The Swedish CArdioPulmonary BioImage Study : objectives and design
- 2015
-
Ingår i: Journal of Internal Medicine. - : Wiley. - 0954-6820 .- 1365-2796. ; 278:6, s. 645-659
-
Tidskriftsartikel (refereegranskat)abstract
- Cardiopulmonary diseases are major causes of death worldwide, but currently recommended strategies for diagnosis and prevention may be outdated because of recent changes in risk factor patterns. The Swedish CArdioPulmonarybioImage Study (SCAPIS) combines the use of new imaging technologies, advances in large-scale 'omics' and epidemiological analyses to extensively characterize a Swedish cohort of 30 000 men and women aged between 50 and 64 years. The information obtained will be used to improve risk prediction of cardiopulmonary diseases and optimize the ability to study disease mechanisms. A comprehensive pilot study in 1111 individuals, which was completed in 2012, demonstrated the feasibility and financial and ethical consequences of SCAPIS. Recruitment to the national, multicentre study has recently started.
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| 58. |
- Eremina, R. M., et al.
(författare)
-
Magnetization and specific heat of the dimer system CuTe(2)O(5)
- 2011
-
Ingår i: European Physical Journal B. - : Springer Science and Business Media LLC. - 1434-6028 .- 1434-6036. ; 84:3, s. 391-395
-
Tidskriftsartikel (refereegranskat)abstract
- We report on magnetization and specific heat measurements on single-crystalline CuTe(2)O(5). The experimental data are directly compared to theoretical results for two different spin structures, namely an alternating spin-chain and a two-dimensional (2D) coupled dimer model, obtained by Das et al. [Phys. Rev. B 77, 224437 (2008)]. While the analysis of the specific heat does not allow to distinguish between the two models, the magnetization data is in good agreement with the 2D coupled dimer model.
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| 59. |
- Fisichella, Valeria A, 1974, et al.
(författare)
-
Evaluation of image quality and lesion perception by human readers on 3D CT colonography: comparison of standard and low radiation dose
- 2010
-
Ingår i: European Radiology. - 1432-1084. ; 20:3, s. 630-9
-
Tidskriftsartikel (refereegranskat)abstract
- AIMS: We compared the prevalence of noise-related artefacts and lesion perception on three-dimensional (3D) CT colonography (CTC) at standard and low radiation doses. METHODS: Forty-eight patients underwent CTC (64 x 0.625 mm collimation; tube rotation time 0.5 s; automatic tube current modulation: standard dose 40-160 mA, low dose 10-50 mA). Low- and standard-dose acquisitions were performed in the supine position, one after the other. The presence of artefacts (cobblestone and snow artefacts, irregularly delineated folds) and the presence of polyps were evaluated by five radiologists on 3D images at standard dose, the original low dose and a modified low dose, i.e. after manipulation of opacity on 3D. RESULTS: The mean effective dose was 3.9 +/- 1.3 mSv at standard dose and 1.03 +/- 0.4 mSv at low dose. The number of images showing cobblestone artefacts and irregularly delineated folds at original and modified low doses was significantly higher than at standard dose (P < 0.0001). Most of the artefacts on modified low-dose images were mild. No significant difference in sensitivity between the dose levels was found for polyps >/=6 mm. CONCLUSIONS: Reduction of the effective dose to 1 mSv significantly affects image quality on 3D CTC, but the perception of >/=6 mm lesions is not significantly impaired.
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| 60. |
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| 61. |
- Fushitani, Mizuho, et al.
(författare)
-
Time-resolved photoelectron imaging of complex resonances in molecular nitrogen
- 2021
-
Ingår i: The Journal of chemical physics. - : AIP Publishing. - 0021-9606 .- 1089-7690. ; 154:14
-
Tidskriftsartikel (refereegranskat)abstract
- We have used the FERMI free-electron laser to perform time-resolved photoelectron imaging experiments on a complex group of resonances near 15.38 eV in the absorption spectrum of molecular nitrogen, N2, under jet-cooled conditions. The new data complement and extend the earlier work of Fushitani et al. [Opt. Express 27, 19702–19711 (2019)], who recorded time-resolved photoelectron spectra for this same group of resonances. Time-dependent oscillations are observed in both the photoelectron yields and the photoelectron angular distributions, providing insight into the interactions among the resonant intermediate states. In addition, for most states, we observe an exponential decay of the photoelectron yield that depends on the ionic final state. This observation can be rationalized by the different lifetimes for the intermediate states contributing to a particular ionization channel. Although there are nine resonances within the group, we show that by detecting individual photoelectron final states and their angular dependence, we can identify and differentiate quantum pathways within this complex system.
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| 62. |
- Fushitani, Mizuho, et al.
(författare)
-
Wave packet dynamics and control in excited states of molecular nitrogen
- 2024
-
Ingår i: The Journal of chemical physics. - 0021-9606. ; 160:10
-
Tidskriftsartikel (refereegranskat)abstract
- Wave packet interferometry with vacuum ultraviolet light has been used to probe a complex region of the electronic spectrum of molecular nitrogen, N2. Wave packets of Rydberg and valence states were excited by using double pulses of vacuum ultraviolet (VUV), free-electron-laser (FEL) light. These wave packets were composed of contributions from multiple electronic states with a moderate principal quantum number (n ∼ 4-9) and a range of vibrational and rotational quantum numbers. The phase relationship of the two FEL pulses varied in time, but as demonstrated previously, a shot-by-shot analysis allows the spectra to be sorted according to the phase between the two pulses. The wave packets were probed by angle-resolved photoionization using an infrared pulse with a variable delay after the pair of excitation pulses. The photoelectron branching fractions and angular distributions display oscillations that depend on both the time delays and the relative phases of the VUV pulses. The combination of frequency, time delay, and phase selection provides significant control over the ionization process and ultimately improves the ability to analyze and assign complex molecular spectra.
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| 63. |
- Garg, D., et al.
(författare)
-
Fragmentation Dynamics of Fluorene Explored Using Ultrafast XUV-Vis Pump-Probe Spectroscopy
- 2022
-
Ingår i: Frontiers in Physics. - : Frontiers Media SA. - 2296-424X. ; 10
-
Tidskriftsartikel (refereegranskat)abstract
- We report on the use of extreme ultraviolet (XUV, 30.3 nm) radiation from the Free-electron LASer in Hamburg (FLASH) and visible (Vis, 405 nm) photons from an optical laser to investigate the relaxation and fragmentation dynamics of fluorene ions. The ultrashort laser pulses allow to resolve the molecular processes occurring on the femtosecond timescales. Fluorene is a prototypical small polycyclic aromatic hydrocarbon (PAH). Through their infrared emission signature, PAHs have been shown to be ubiquitous in the universe, and they are assumed to play an important role in the chemistry of the interstellar medium. Our experiments track the ionization and dissociative ionization products of fluorene through time-of-flight mass spectrometry and velocity-map imaging. Multiple processes involved in the formation of each of the fragment ions are disentangled through analysis of the ion images. The relaxation lifetimes of the excited fluorene monocation and dication obtained through the fragment formation channels are reported to be in the range of a few tens of femtoseconds to a few picoseconds.
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| 64. |
- Gastineau, R., et al.
(författare)
-
Small-scale lobate hillslope features on Mars: A comparative 3D morphological study with terrestrial solifluction lobes and zebra stripe lobes
- 2020
-
Ingår i: Icarus. - : Elsevier BV. - 0019-1035. ; 342
-
Tidskriftsartikel (refereegranskat)abstract
- Small-scale lobes (SSL) observed at the surface of Mars are thought to be the result of solifluction. Hence, their existence has important implications for our understanding of recent climate history, the distribution of thaw liquids and its geomorphic effects, as water is believed not to have been recently stable at the martian surface. These small-scale lobes are limited to sloping terrains and often occur alongside polygonal patterned ground attesting to the presence of ice in the environment. In this study, we perform a comparative 3D morphometric analysis of the lobes on Mars with terrestrial analogues. We use data from High Resolution Imaging Science Experiment (HiRISE) camera in order to create Digital Terrain Models (DTMs) on Mars at 1 m/pix. For the terrestrial analogues, we use DTMs and orthophotos from five periglacial environments with solifluction lobes and from one site with lobate features found in the Atacama Desert. The lobate features in the Atacama Desert are found within features called “zebra stripes”, which are apparently unique to the Atacama and are now generally accepted to be the result of seismic shaking. We show that SSL on Mars overlap morphometrically with terrestrial solifluction lobes, and are less similar to zebra stripe lobes. The majority of martian SSL occur below the angle of repose which demonstrates that a dry fall mechanism cannot be responsible for their formation and that lubrication of the subsurface is required. We found that martian SSL only occur on slopes greater than ~10°, a constraint not observed for terrestrial solifluction lobes nor zebra stripe lobes in Atacama. We hypothesise that this apparent constraint does not result from the lowered gravity on Mars, but instead from differing soil properties and/or thermal regime between Mars and Earth which affects the slope at which creep can initiate. We cannot rule out a role of CO2 sublimation in lobe-formation based on our terrestrial measurements. © 2019 Elsevier Inc.
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| 65. |
- Geissbuehler, M., et al.
(författare)
-
Triplet imaging of oxygen consumption during the contraction of a single smooth muscle cell (A7r5)
- 2012
-
Ingår i: Oxygen Transport to Tissue XXXIII. - New York, NY : Springer Science+Business Media B.V.. - 9781461415657 ; , s. 263-268
-
Konferensbidrag (refereegranskat)abstract
- Triplet imaging is a novel optical technique that allows investigating oxygen metabolism at the single cell and the sub-cellular level. The method combines high temporal and spatial resolutions which are required for the monitoring of fast kinetics of oxygen concentration in living cells. Calibration and validation are demonstrated with a titration experiment using l-ascorbic acid with the enzyme ascorbase oxidase. The method was applied to a biological cell system, employing as reporter a cytosolic fusion protein of β-galactosidase with a SNAP-tag labeled with tetramethylrhodamine. Oxygen consumption in single smooth muscle cells A7r5 during an [Arg8]-vasopressin- induced contraction is measured. The triplet lifetime images over time can be related to an intracellular oxygen consumption corresponding to a mono-exponentially decaying intracellular oxygen concentration. This is in good agreement with previously reported measurements of oxygen consumption in skeletal muscle fibers.
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| 66. |
- Gering, E., et al.
(författare)
-
Mixed ancestry and admixture in Kauai's feral chickens: invasion of domestic genes into ancient Red Junglefowl reserviors
- 2015
-
Ingår i: Molecular Ecology. - : John Wiley & Sons. - 0962-1083 .- 1365-294X. ; 24:9, s. 2112-2124
-
Tidskriftsartikel (refereegranskat)abstract
- A major goal of invasion genetics is to determine how establishment histories shape non-native organisms' genotypes and phenotypes. While domesticated species commonly escape cultivation to invade feral habitats, few studies have examined how this process shapes feral gene pools and traits. We collected genomic and phenotypic data from feral chickens (Gallus gallus) on the Hawaiian island of Kauai to (i) ascertain their origins and (ii) measure standing variation in feral genomes, morphology and behaviour. Mitochondrial phylogenies (D-loop & whole Mt genome) revealed two divergent clades within our samples. The rare clade also contains sequences from Red Junglefowl (the domestic chicken's progenitor) and ancient DNA sequences from Kauai that predate European contact. This lineage appears to have been dispersed into the east Pacific by ancient Polynesian colonists. The more prevalent MtDNA clade occurs worldwide and includes domesticated breeds developed recently in Europe that are farmed within Hawaii. We hypothesize this lineage originates from recently feralized livestock and found supporting evidence for increased G. gallus density on Kauai within the last few decades. SNPs obtained from whole-genome sequencing were consistent with historic admixture between Kauai's divergent (G. gallus) lineages. Additionally, analyses of plumage, skin colour and vocalizations revealed that Kauai birds' behaviours and morphologies overlap with those of domestic chickens and Red Junglefowl, suggesting hybrid origins. Together, our data support the hypotheses that (i) Kauai's feral G. gallus descend from recent invasion(s) of domestic chickens into an ancient Red Junglefowl reservoir and (ii) feral chickens exhibit greater phenotypic diversity than candidate source populations. These findings complicate management objectives for Pacific feral chickens, while highlighting the potential of this and other feral systems for evolutionary studies of invasions.
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| 67. |
- Gering, E., et al.
(författare)
-
Signals of selection and ancestry in independently feral Gallus gallus populations
- 2024
-
Ingår i: Molecular Ecology. - : WILEY. - 0962-1083 .- 1365-294X.
-
Tidskriftsartikel (refereegranskat)abstract
- Recent work indicates that feralisation is not a simple reversal of domestication, and therefore raises questions about the predictability of evolution across replicated feral populations. In the present study we compare genes and traits of two independently established feral populations of chickens (Gallus gallus) that inhabit archipelagos within the Pacific and Atlantic regions to test for evolutionary parallelism and/or divergence. We find that feral populations from each region are genetically closer to one another than other domestic breeds, despite their geographical isolation and divergent colonisation histories. Next, we used genome scans to identify genomic regions selected during feralisation (selective sweeps) in two independently feral populations from Bermuda and Hawaii. Three selective sweep regions (each identified by multiple detection methods) were shared between feral populations, and this overlap is inconsistent with a null model in which selection targets are randomly distributed throughout the genome. In the case of the Bermudian population, many of the genes present within the selective sweeps were either not annotated or of unknown function. Of the nine genes that were identifiable, five were related to behaviour, with the remaining genes involved in bone metabolism, eye development and the immune system. Our findings suggest that a subset of feralisation loci (i.e. genomic targets of recent selection in feral populations) are shared across independently established populations, raising the possibility that feralisation involves some degree of parallelism or convergence and the potential for a shared feralisation 'syndrome'.
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| 68. |
- Gryzlova, E. V., et al.
(författare)
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Influence of an atomic resonance on the coherent control of the photoionization process
- 2022
-
Ingår i: Physical Review Research. - 2643-1564. ; 4:3
-
Tidskriftsartikel (refereegranskat)abstract
- In coherent control schemes, pathways connecting an initial and a final state can be independently controlled by manipulating the complex amplitudes of their transition matrix elements. For paths characterized by the absorption of multiple photons, these quantities depend on the magnitude and phase between the intermediate steps, and are expected to be strongly affected by the presence of resonances. We investigate the coherent control of the photoemission process in neon using a phase-controlled two-color extreme ultraviolet pulse with frequency in proximity of an excited energy state. Using helium as a reference, we show that the presence of such a resonance in neon modifies the amplitude and phase of the asymmetric emission of photoelectrons. Theoretical simulations based on perturbation theory are in fair agreement with the experimental observations.
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| 69. |
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| 70. |
- Hansen, T. F., et al.
(författare)
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MicroRNA-126 and epidermal growth factor-like domain 7-an angiogenic couple of importance in metastatic colorectal cancer. Results from the Nordic ACT trial
- 2013
-
Ingår i: British Journal of Cancer. - : Springer Science and Business Media LLC. - 1532-1827 .- 0007-0920. ; 109:5, s. 1243-1251
-
Tidskriftsartikel (refereegranskat)abstract
- Background: This study investigated the clinical importance of linked angiogenetic biomarkers to chemotherapy, combined with the anti-vascular endothelial growth factor A (anti-VEGF-A), as a first-line treatment in patients with metastatic colorectal cancer (mCRC). Methods: A total of 230 patients from a randomised phase III study were included. The primary microRNA-126 (pri-miRNA-126) A24G single-nucleotide polymorphism and the mature miRNA-126 were analysed by PCR using genomic DNA (full blood) and formalin-fixed paraffin-embedded tissue sections, respectively. The epidermal growth factor-like domain 7 (EGFL7) protein was visualised and quantified using immunohistochemistry. Results: High tumour expression of miRNA-126 was significantly related to a longer progression-free survival. The independent prognostic value of miRNA-126 was confirmed using a Cox regression analysis (hazard ratio = 0.49, 95% confidence interval = 0.29-0.84, P = 0.009). Although not significant, a relationship between EGFL7 expression and response rates is suggested, with EGFL7 expression at the invasive front being lower in responding patients than in the non-responders (P = 0.063). Conclusion: The results validate the previous findings on the prognostic value of miRNA-126 in mCRC and may suggest a relationship between treatment efficacy and EGFL7 expression. As miRNA-126 may target VEGF-A as well as EGFL7, the results may provide predictive information in relation to next-generation anti-angiogenetics.
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| 71. |
- Harris, M., et al.
(författare)
-
The Kumbis and Nagatis Formations and the Helmeringhausen Gabbro: Oldest undeformed rocks of the Sinclair Supergroup in Namibia
- 2020
-
Ingår i: Journal of African Earth Sciences. - : Elsevier BV. - 1464-343X. ; 165
-
Tidskriftsartikel (refereegranskat)abstract
- The Mesoproterozoic rocks of the Kumbis and Nagatis Formations and Helmeringhausen Gabbro in Southern Namibia are now recognised as the oldest rocks in the sedimentary and volcanic Sinclair Supergroup. The stratigraphic subdivision and plate tectonic setting are still debated and reliable ages are sparse. This work investigates the relatively undeformed felsic and mafic lava of the Kumbis Formation, rhyolitic lava of the Nagatis Formation and the intrusive Helmeringhausen Gabbro. Microscopic and field investigation reveals no evidence of regional metamorphism in these units. Ion probe U-Pb zircon dating yields ages of 1374 +/- 7 Ma to 1358 +/- 5 Ma (2 sigma) for the Kumbis Formation, 1363 +/- 11 Ma for the Nagatis Formation and 1372 +/- 12 Ma for the Helmeringhausen Gabbro. These dates are in contrast to the published stratigraphy in which the Helmeringhausen Gabbro was regarded as much older than the Kumbis Formation and both were excluded from the Sinclair Supergroup, whereas the Nagatis Formation was considered to be younger and was included as the oldest unit of the Sinclair Supergroup. Lu-Hf data on zircon indicates different magma sources for the Kumbis and Nagatis Formations, implying that although they are time equivalent, they are not co-magmatic. The geochemical data suggests that the most felsic rocks contain large amounts of older crustal material, from which their apparent subduction signatures were inherited. The more mafic rocks also contain minor crustal components mixed with material derived from depleted mantle. The Helmeringhausen Gabbro is similar to coeval hybrid gabbros at Neuhof Valley 150 Km to the north and they are grouped in the intrusive Helmering Suite. Taking the regional context into account, these oldest rocks of the Sinclair Supergroup probably formed in a rift environment which split the Rehoboth Province apart at the beginning of the Mesoproterozoic Namaqua-Natal Wilson Cycle.
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| 72. |
- Haugen, H.A., et al.
(författare)
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Infrastructure for CCS in the Skagerrak/Kattegat region, Southern Scandinavia: A feasibility study
- 2013
-
Ingår i: Energy Procedia. - : Elsevier BV. - 1876-6102. ; 37, s. 2562-2569
-
Konferensbidrag (refereegranskat)abstract
- This paper gives an overview of results from a project which explored the feasibility of establishing a CO2 Capture and Storage infrastructure in the Skagerrak/Kattegat region of Southern Scandinavia. This involves assessment of the technical and economic parameters of the complete CCS chain and, in particular, identification of possible storage locations. The project ran from June 2009 to December 2011. Emissions from three major industrial clusters in the Skagerrak/Kattegat region - Gothenburg in Sweden, Grenland in Telemark County, southern Norway and Aalborg in Denmark - were targeted. Both emissions from process industries as well as power plants were included.
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| 73. |
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| 74. |
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| 75. |
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| 76. |
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| 77. |
- Ho, Ching-Tien, et al.
(författare)
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An Efficient Algorithm for Gray–to–Binary Permutation on Hypercubes
- 1994
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Ingår i: Journal of Parallel and Distributed Computing. - 0743-7315 .- 1096-0848. ; 20:1, s. 114-120
-
Tidskriftsartikel (refereegranskat)abstract
- Both Gray code and binary code are frequently used in mapping arrays into hypercube architectures. While the former is preferred when communication between adjacent array elements is needed, the latter is preferred for FFT-type communication. When different phases of computations have different types of communication patterns, the need arises to remap the data. We give a nearly optimal algorithm for permuting data from a Gray code mapping to a binary code mapping on a hypercube with communication restricted to one input and one output channel per node at a time. Our algorithm improves over the best previously known algorithm [6] by nearly a factor of two and is optimal to within a factor of n=(n Gamma 1) with respect to data transfer time on an n-cube. The expected speedup is confirmed by measurements on an Intel iPSC/2 hypercube
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| 78. |
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| 79. |
- Hägg, Ingemund, et al.
(författare)
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Gör det ont när knoppar brister?
- 1986
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Ingår i: Ledarskap. ; :8-9, s. 48-51
-
Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 80. |
- Häsä, H., et al.
(författare)
-
Co-firing of coal and biomass in Circulating Fluidized Beds
- 2006
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Ingår i: 6th European Conference on Coal Research and its Applications.
-
Konferensbidrag (refereegranskat)abstract
- To fulfil the development needs of OTSC CFB technology, a comprehensive understanding of CFB combustion processes needed to be achieved. Intensive research in laboratory, pilot and fullscale combustors is required to fulfil the abovementioned objectives.In order to study different process characteristics and verify measurements and simulations, experiments were carried out with different size reactors; VTT’s laboratory scale CFB reactor, VTT’s 50 kW pilot CFB reactor, Chalmers’ 12 MW CFB boiler, cold rig and with several commercial boilers.
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| 81. |
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| 82. |
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| 83. |
- Johansson, J, et al.
(författare)
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Active or passive chest drainage after oesophagectomy in 101 patients : a prospective randomized study
- 1998
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Ingår i: British Journal of Surgery. - 0007-1323. ; 85:8, s. 6-1143
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: This study evaluates the efficiency and safety of two methods of chest drainage after uncomplicated oesophagectomy.METHODS: A prospective randomized study between active suction drainage and passive chest drainage was carried out in 101 patients who underwent gastric pull-up oesophagectomy.RESULTS: No difference in the prevalence of pneumothorax during treatment was noted between the active (nine of 55) and the passive (four of 46) drainage groups (P=0.20). Nor was there any difference in the size (P=0.46) and duration (P=0.53) of the pneumothorax. There was no significant difference in right (P=0.84) and left (P=0.61) basal atelectases and the amounts of right (P=0.10) and left (P=0.24) pleural effusions. There were significantly more basal atelectases (P < 0.001) and pleural effusions (P<0.001) in the non-operated left side compared with the operated right side. Postoperative hospital stay was the same in both groups (median 13 days; P=0.86). The hospital mortality rate was two of 101, and was not affected by the type of drainage.CONCLUSION: Passive drainage did not reduce hospital stay, but was as safe and effective as the active system in draining the pleural cavity after uncomplicated oesophagectomy.
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| 84. |
- Johansson, J, et al.
(författare)
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Adenocarcinoma in the distal esophagus with and without Barrett esophagus. Differences in symptoms and survival rates
- 1996
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Ingår i: Archives of Surgery. - : American Medical Association (AMA). - 0004-0010. ; 131:7, s. 13-708
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: To evaluate differences in clinical appearance and survival rates in patients operated on for adenocarcinoma in the distal esophagus with and without Barrett epithelium.DESIGN: Prospective clinical study.SETTING: University hospital, Sweden.PATIENTS: Fifty-four patients with adenocarcinoma in the distal esophagus with (n = 17) or without (n = 37) Barrett epithelium.INTERVENTION: Esophagectomy or total gastrectomy.MAIN OUTCOME MEASURES: Preoperative symptoms, endoscopic results, and histological findings; postoperative morbidity, mortality, and survival rates.RESULTS: The main indication for the endoscopic examination that revealed tumor in the group with Barrett esophagus was reflex-related symptoms in 6 patients (routine Barrett examination, n = 4; symptoms of reflux, n = 2), symptoms related to upper gastrointestinal tract bleeding in 6, and malignant symptoms in 5 (dysphagia, n = 4; weight loss, n = 1). In contrast, most patients in the cardia cancer group were admitted because of malignant symptoms (dysphagia, n = 26; epigastric pain, n = 9; and anemia, n = 2). Ten of 17 patients in the Barrett esophagus cancer group had tumors limited to the mucosa and submucosa only. In 1 patient the tumor grew into the muscular layer but not through it. In the remaining 6 patients the tumor did grow through the muscular layer and lymph node metastases were found. Wall penetration was found in 30 patients and metastases to lymph nodes in 29 patients in the cardia cancer group. The hospital mortality rate was 0 of 17 patients in the Barrett cancer group and 2 of 37 patients in the cardia cancer group. In the patients operated on for adenocarcinoma in the distal esophagus, a better long-term survival rate was seen in those with Barrett epithelium (50%) than in those without this metaplasia (10%) (log rank P = .005; X2 = 7.80).CONCLUSIONS: Concomitant Barrett epithelium improved the prognosis for patients with adenocarcinoma in the distal esophagus. Probably the reason for this was a higher rate of early-stage disease, because symptoms of gastroesophageal reflux and other benign disorders, not dysphagia, were most common in patients with adenocarcinoma without Barrett epithelium in the distal esophagus.
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| 85. |
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| 86. |
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| 88. |
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| 89. |
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| 90. |
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| 91. |
- Johnsson, JI, et al.
(författare)
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Fitness-related effects of growth investment in brown trout under field and hatchery conditions
- 2000
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Ingår i: JOURNAL OF FISH BIOLOGY. - : ACADEMIC PRESS LTD. - 0022-1112. ; 57:2, s. 326-336
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Tidskriftsartikel (refereegranskat)abstract
- The mortality of brown trout Salmo trutta over winter in a near-natural stream was not significantly increased by growth hormone (GH) treatment, but lipid reserves were lower in GN-treated fish. As GH-treated trout grew Faster than controls. GH appears to
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| 92. |
- Johnsson, Linus, 1978-, et al.
(författare)
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The voice of the profession : how the ethical demand is professionally refracted in the work of general practitioners
- 2023
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Ingår i: BMC Medical Ethics. - : BioMed Central (BMC). - 1472-6939. ; 24:1
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Among the myriad voices advocating diverging ideas of what general practice ought to be, none seem to adequately capture its ethical core. There is a paucity of attempts to integrate moral theory with empirical accounts of the embodied moral knowledge of GPs in order to inform a general normative theory of good general practice. In this article, we present an empirically grounded model of the professional morality of GPs, and discuss its implications in relation to ethical theories to see whether it might be sustainable as a general practice ethic.METHODS: We observed and interviewed sixteen GPs and GP residents working in health care centres in four Swedish regions between 2015-2017. In keeping with Straussian Grounded Theory, sampling was initially purposeful and later theoretically guided, and data generation, analysis and theoretical integration proceeded in parallel. The focal concept of this article was refined through multidimensional property supplementation.RESULTS: The voice of the profession is one of four concepts in our emerging theory that attempt to capture various motives that affect GPs' everyday moral decisionmaking. It reflects how GPs appreciate the situation by passing three professional-moral judgments: Shall I see what is before me, or take a bird's-eye view? Shall I intervene, or stay my hand? And do I need to speak up, or should I rather shut up? By thus framing the problem, the GP narrows down the range of considerations, allowing them to focus on its morally most pertinent aspects. This process is best understood as a way of heeding Løgstrup's ethical demand. Refracted through the lens of the GP's professional understanding of life, the ethical demand gives rise to specific moral imperatives that may stand in opposition to the express wishes of the other, social norms, or the GP's self-interest.CONCLUSIONS: The voice of the profession makes sense of how GPs frame problematic situations in moral terms. It is coherent enough to be sustainable as a general practice ethic, and might be helpful in explaining why ethical decisions that GPs intuitively understand as justified, but for which social support is lacking, can nevertheless be legitimate.
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| 93. |
- Johnsson, Magnus, 1983, et al.
(författare)
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SARS-COV-2 a trigger of myelin oligodendrocyte glycoprotein-associated disorder
- 2022
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Ingår i: Annals of Clinical and Translational Neurology. - : Wiley. - 2328-9503. ; 9:8, s. 1296-1301
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Tidskriftsartikel (refereegranskat)abstract
- SARS-COV-2 frequently cause neurological disorders and is sometimes associated with onset of autoimmune diseases affecting the nervous system. Over recent years, a rare but distinct diagnosis designated myelin oligodendrocyte glycoprotein-associated disorder (MOGAD) has been recognized in patients with attacks of optic neuritis, myelitis, or encephalomyelitis and increased levels of anti-MOG antibodies. The cause of MOGAD is unknown. However, there have been reports of single cases of MOGAD in patients with Covid-19 infection. We report a series of SARS-CoV-2 positive patients that developed MOGAD, but a homology search did not support a cross-reactive immune response to SARS-CoV-2 spike-protein and MOG.
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| 94. |
- Johnsson, Magnus, 1983, et al.
(författare)
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Serum neurofilament light for detecting disease activity in individual patients in multiple sclerosis: A 48-week prospective single-center study
- 2024
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Ingår i: MULTIPLE SCLEROSIS JOURNAL. - 1352-4585 .- 1477-0970. ; 30:6, s. 664-673
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Tidskriftsartikel (refereegranskat)abstract
- Background: Serum neurofilament light (sNfL) reflects neuroaxonal damage and is now used as an outcome in treatment trials of relapsing-remitting multiple sclerosis (RRMS). However, the diagnostic properties of sNfL for monitoring disease activity in individual patients warrant further investigations. Method: Patients with suspected relapse and/or contrast-enhancing lesions (CELs) were consecutively included and performed magnetic resonance imaging (MRI) of the brain at baseline and weeks 28 and 48. Serum was obtained at baseline and 2, 4, 8, 16, 24, and 48 weeks. Neurofilament light concentration was measured using Single molecule array technology. Results: We included 44 patients, 40 with RRMS and 4 with clinically isolated syndrome. The median sNfL level peaked at 2 weeks post-baseline (14.6 ng/L, interquartile range (IQR); 9.3-31.6) and reached nadir at 48 weeks (9.1 ng/L, IQR; 5.5-15.0), equivalent to the median sNfL of controls (9.1 ng/L, IQR; 7.4-12). A baseline Z-score of more than 1.1 (area under the curve; 0.78, p < 0.0001) had a sensitivity of 81% and specificity of 70% to detect disease activity. Conclusion: One out of five patients with relapse and/or CELs did not change significantly in post-baseline sNfL levels. The utility of repeated sNfL measurements to monitor disease activity is complementary rather than a substitute for clinical and MRI measures.
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| 95. |
- Johnsson, Per, et al.
(författare)
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Characterization of a two-color pump-probe setup at FLASH using a velocity map imaging spectrometer
- 2010
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Ingår i: Optics Letters. - 0146-9592. ; 35:24, s. 4163-4165
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Tidskriftsartikel (refereegranskat)abstract
- We report on the implementation of a high-count-rate charged particle imaging detector for two-color pump-probe experiments at the free electron laser in Hamburg (FLASH). In doing so, we have developed a procedure for finding the spatial and temporal overlap between the extreme UV free electron laser (FEL) pulses and the IR pulses, which allows for complete alignment of the setup in situations where the region of overlap between the FEL and the IR is not easily accessible by means of imaging optics. (C) 2010 Optical Society of America
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| 96. |
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| 100. |
- Kukk, E., et al.
(författare)
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Formative period in the x-ray-induced photodissociation of organic molecules
- 2021
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Ingår i: Physical Review Research. - 2643-1564. ; 3:1
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Tidskriftsartikel (refereegranskat)abstract
- Absorption of x-ray photons by atomic inner shells of light-element organics and biomolecules often leads to formation of dicationic electronic states and to molecular fragmentation. We investigated the x-ray-induced dissociation landscape of a representative medium-sized organic molecule, thiophene, by femtosecond x-ray pulses from the Super Photon Ring-8 GeV (SPring-8) Angstrom Compact Free-Electron Laser (SACLA). Holes, created in the sulfur 2p orbital by photoemission, were filled by the Auger process that created dicationic molecular states within a broad range of internal energies—a starting point particular to x-ray-induced dynamics. The evolution of the ionized molecules was monitored by a pump-probe experiment using a near-infrared (800 nm) laser pulse. Ion-ion coincidence and ion momentum analysis reveals enhanced yields of ionic fragments from multibody breakup of the ring, attributed to additional ionization of the highly excited fraction of the dicationic parent molecular states. The transient nature of the enhancement and its decay with about a 160-fs time constant indicate formation of an open-ring parent geometry and the statistical survival time of the parent species before the dissociation events. By probing specific Auger final states of transient, highly excited nature by near-infrared light, we demonstrate how pump-probe signatures can be related to the key features in dynamics during the early period of the x-ray-induced damage of organic molecules and biomolecules.
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