| 51. |
- Manry, Jérémy, et al.
(author)
-
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies.
- 2022
-
In: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 1091-6490. ; 119:21
-
Journal article (peer-reviewed)abstract
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection fatality rate (IFR) doubles with every 5 y of age from childhood onward. Circulating autoantibodies neutralizing IFN-α, IFN-ω, and/or IFN-β are found in ∼20% of deceased patients across age groups, and in ∼1% of individuals aged <70 y and in >4% of those >70 y old in the general population. With a sample of 1,261 unvaccinated deceased patients and 34,159 individuals of the general population sampled before the pandemic, we estimated both IFR and relative risk of death (RRD) across age groups for individuals carrying autoantibodies neutralizing type I IFNs, relative to noncarriers. The RRD associated with any combination of autoantibodies was higher in subjects under 70 y old. For autoantibodies neutralizing IFN-α2 or IFN-ω, the RRDs were 17.0 (95% CI: 11.7 to 24.7) and 5.8 (4.5 to 7.4) for individuals <70 y and ≥70 y old, respectively, whereas, for autoantibodies neutralizing both molecules, the RRDs were 188.3 (44.8 to 774.4) and 7.2 (5.0 to 10.3), respectively. In contrast, IFRs increased with age, ranging from 0.17% (0.12 to 0.31) for individuals <40 y old to 26.7% (20.3 to 35.2) for those ≥80 y old for autoantibodies neutralizing IFN-α2 or IFN-ω, and from 0.84% (0.31 to 8.28) to 40.5% (27.82 to 61.20) for autoantibodies neutralizing both. Autoantibodies against type I IFNs increase IFRs, and are associated with high RRDs, especially when neutralizing both IFN-α2 and IFN-ω. Remarkably, IFRs increase with age, whereas RRDs decrease with age. Autoimmunity to type I IFNs is a strong and common predictor of COVID-19 death.
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| 52. |
- Martin, Lisa J., et al.
(author)
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Country-Specific vs. Common Birthweight-for-Gestational Age References to Identify Small for Gestational Age Infants Born at 24-28 weeks : An International Study
- 2016
-
In: Paediatric and Perinatal Epidemiology. - : Wiley. - 0269-5022 .- 1365-3016. ; 30:5, s. 450-461
-
Journal article (peer-reviewed)abstract
- Background: Controversy exists as to whether birthweight-for-gestational age references used to classify infants as small for gestational age (SGA) should be country specific or based on an international (common) standard. We examined whether different birthweight-for-gestational age references affected the association of SGA with adverse outcomes among very preterm neonates.Methods: Singleton infants (n = 23 788) of 24(0)-28(6) weeks' gestational age in nine high-resource countries were classified as SGA (<10th centile) using common and country-specific references based on birthweight and estimated fetal weight (EFW). For each reference, the adjusted relative risk (aRR) for the association of SGA with composite outcome of mortality or major morbidity was estimated.Results: The percentage of infants classified as SGA differed slightly for common compared with country specific for birthweight references [9.9% (95% CI 9.5, 10.2) vs. 11.1% (95% CI 10.7, 11.5)] and for EFW references [28.6% (95% CI 28.0, 29.2) vs. 24.6% (95% CI 24.1, 25.2)]. The association of SGA with the composite outcome was similar when using common or country-specific references for the total sample for birthweight [aRRs 1.47 (95% CI 1.43, 1.51) and 1.48 (95% CI 1.44, 1.53) respectively] and for EFW references [aRRs 1.35 (95% CI 1.31, 1.38) and 1.39 (95% CI 1.35, 1.43) respectively].Conclusion: Small for gestational age is associated with higher mortality and morbidity in infants born <29 weeks' gestational age. Although common and country-specific birthweight/EFW references identified slightly different proportions of SGA infants, the risk of the composite outcome was comparable.
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| 53. |
- Martin, Maria A., et al.
(author)
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Ten new insights in climate science 2021 : a horizon scan
- 2021
-
In: Global Sustainability. - : Cambridge University Press (CUP). - 2059-4798. ; 4, s. 1-20
-
Research review (peer-reviewed)abstract
- Non-technical summary: We summarize some of the past year's most important findings within climate change-related research. New research has improved our understanding about the remaining options to achieve the Paris Agreement goals, through overcoming political barriers to carbon pricing, taking into account non-CO2 factors, a well-designed implementation of demand-side and nature-based solutions, resilience building of ecosystems and the recognition that climate change mitigation costs can be justified by benefits to the health of humans and nature alone. We consider new insights about what to expect if we fail to include a new dimension of fire extremes and the prospect of cascading climate tipping elements.Technical summary: A synthesis is made of 10 topics within climate research, where there have been significant advances since January 2020. The insights are based on input from an international open call with broad disciplinary scope. Findings include: (1) the options to still keep global warming below 1.5 °C; (2) the impact of non-CO2 factors in global warming; (3) a new dimension of fire extremes forced by climate change; (4) the increasing pressure on interconnected climate tipping elements; (5) the dimensions of climate justice; (6) political challenges impeding the effectiveness of carbon pricing; (7) demand-side solutions as vehicles of climate mitigation; (8) the potentials and caveats of nature-based solutions; (9) how building resilience of marine ecosystems is possible; and (10) that the costs of climate change mitigation policies can be more than justified by the benefits to the health of humans and nature.Social media summary: How do we limit global warming to 1.5 °C and why is it crucial? See highlights of latest climate science.
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| 54. |
- Momose, Munetake, et al.
(author)
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Detailed structure of the outer disk around HD169142 with polarized light in H-band
- 2015
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In: Nippon Tenmon Gakkai obun kenkyu hokoku. - : Oxford University Press (OUP). - 0004-6264. ; 67:5
-
Journal article (peer-reviewed)abstract
- Coronagraphic imagery of the circumstellar disk around HD 169142 in H-band polarized intensity (PI) with Subaru/HiCIAO is presented. The emission scattered by dust particles at the disk surface in 0.2 <= r <= 1.2, or 29 <= r <= 174 AU, is successfully detected. The azimuthally-averaged radial profile of the PI shows a double power-law distribution, in which the PIs in r=29-52 AU and r=81.2-145 AU respectively show r(-3)-dependence. These two power-law regions are connected smoothly with a transition zone (TZ), exhibiting an apparent gap in r=40-70 AU. The PI in the inner power-law region shows a deep minimum whose location seems to coincide with the point source at lambda = 7 mm. This can be regarded as another sign of a protoplanet in TZ. The observed radial profile of the PI is reproduced by a minimally flaring disk with an irregular surface density distribution or with an irregular temperature distribution or with the combination of both. The depletion factor of surface density in the inner power-law region (r<50 AU) is derived to be >= 0.16 from a simple model calculation. The obtained PI image also shows small scale asymmetries in the outer power-law region. Possible origins for these asymmetries include corrugation of the scattering surface in the outer region, and shadowing effect by a puffed up structure in the inner power-law region.
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| 55. |
- Mullins, Niamh, et al.
(author)
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Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
- 2022
-
In: Biological Psychiatry. - : Elsevier. - 0006-3223 .- 1873-2402. ; 91:3, s. 313-327
-
Journal article (peer-reviewed)abstract
- BACKGROUND: Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic etiology, which is partially shared and partially distinct from that of related psychiatric disorders.METHODS: We conducted a genome-wide association study (GWAS) of 29,782 suicide attempt (SA) cases and 519,961 controls in the International Suicide Genetics Consortium (ISGC). The GWAS of SA was conditioned on psychiatric disorders using GWAS summary statistics via multitrait-based conditional and joint analysis, to remove genetic effects on SA mediated by psychiatric disorders. We investigated the shared and divergent genetic architectures of SA, psychiatric disorders, and other known risk factors.RESULTS: Two loci reached genome-wide significance for SA: the major histocompatibility complex and an intergenic locus on chromosome 7, the latter of which remained associated with SA after conditioning on psychiatric disorders and replicated in an independent cohort from the Million Veteran Program. This locus has been implicated in risk-taking behavior, smoking, and insomnia. SA showed strong genetic correlation with psychiatric disorders, particularly major depression, and also with smoking, pain, risk-taking behavior, sleep disturbances, lower educational attainment, reproductive traits, lower socioeconomic status, and poorer general health. After conditioning on psychiatric disorders, the genetic correlations between SA and psychiatric disorders decreased, whereas those with nonpsychiatric traits remained largely unchanged.CONCLUSIONS: Our results identify a risk locus that contributes more strongly to SA than other phenotypes and suggest a shared underlying biology between SA and known risk factors that is not mediated by psychiatric disorders.
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| 56. |
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| 57. |
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| 58. |
- Parameswaran, Poornima, et al.
(author)
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Six RNA Viruses and Forty-One Hosts : Viral Small RNAs and Modulation of Small RNA Repertoires in Vertebrate and Invertebrate Systems
- 2010
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In: PLoS Pathogens. - : Public Library of Science (PLoS). - 1553-7366 .- 1553-7374. ; 6:2, s. e1000764-
-
Journal article (peer-reviewed)abstract
- We have used multiplexed high-throughput sequencing to characterize changes in small RNA populations that occur during viral infection in animal cells. Small RNA-based mechanisms such as RNA interference (RNAi) have been shown in plant and invertebrate systems to play a key role in host responses to viral infection. Although homologs of the key RNAi effector pathways are present in mammalian cells, and can launch an RNAi-mediated degradation of experimentally targeted mRNAs, any role for such responses in mammalian host-virus interactions remains to be characterized. Six different viruses were examined in 41 experimentally susceptible and resistant host systems. We identified virus-derived small RNAs (vsRNAs) from all six viruses, with total abundance varying from "vanishingly rare'' (less than 0.1% of cellular small RNA) to highly abundant (comparable to abundant micro-RNAs "miRNAs''). In addition to the appearance of vsRNAs during infection, we saw a number of specific changes in host miRNA profiles. For several infection models investigated in more detail, the RNAi and Interferon pathways modulated the abundance of vsRNAs. We also found evidence for populations of vsRNAs that exist as duplexed siRNAs with zero to three nucleotide 39 overhangs. Using populations of cells carrying a Hepatitis C replicon, we observed strand-selective loading of siRNAs onto Argonaute complexes. These experiments define vsRNAs as one possible component of the interplay between animal viruses and their hosts.
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| 59. |
- Rich, Evan A., et al.
(author)
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The fundamental stellar parameters of FGK stars in the SEEDS survey Norman, OK 73071, USA
- 2017
-
In: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 472:2, s. 1736-1752
-
Journal article (peer-reviewed)abstract
- Large exoplanet surveys have successfully detected thousands of exoplanets to-date. Utilizing these detections and non-detections to constrain our understanding of the formation and evolution of planetary systems also requires a detailed understanding of the basic properties of their host stars. We have determined the basic stellar properties of F, K and G stars in the Strategic Exploration of Exoplanets and Disks with Subaru (SEEDS) survey from Echelle spectra taken at the Apache Point Observatory's 3.5m telescope. Using ROBOSPECT to extract line equivalent widths and TemperatureGravity microtrubulentVelocity ITerations to calculate the fundamental parameters, we have computed T-eff, log(g), v(t), [Fe/H], chromospheric activity and the age for our sample. Our methodology was calibrated against previously published results for a portion of our sample. The distribution of [Fe/H] in our sample is consistent with that typical of the Solar neighbourhood. Additionally, we find the ages of most of our sample are < 500 Myr, but note that we cannot determine robust ages from significantly older stars via chromospheric activity age indicators. The futuremeta-analysis of the frequency ofwide stellar and sub-stellar companions imaged via the SEEDS survey will utilize our results to constrain the occurrence of detected comoving companions with the properties of their host stars.
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| 60. |
- Shah, Prakesh S., et al.
(author)
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Five-minute Apgar score and outcomes in neonates of 24-28 weeks' gestation
- 2022
-
In: Archives of Disease in Childhood. - : BMJ. - 1359-2998 .- 1468-2052. ; 107:4, s. 437-446
-
Journal article (peer-reviewed)abstract
- OBJECTIVES: To assess associations between 5 min Apgar score and mortality and severe neurological injury (SNI) and to report test characteristics in preterm neonates. DESIGN, SETTING AND PATIENTS: Retrospective cohort study of neonates 240 to 286 weeks' gestation born between 2007 and 2016 and admitted to neonatal units in 11 high-income countries. EXPOSURE: 5 min Apgar score. MAIN OUTCOME MEASURES: In-hospital mortality and SNI defined as grade 3 or 4 periventricular/intraventricular haemorrhage or periventricular leukomalacia. Outcome rates were calculated for each Apgar score and compared after adjustment. The diagnostic characteristics and ORs for each value from 0 versus 1-10 to 0-9 versus 10, with 1-point increments were calculated. RESULTS: Among 92 412 included neonates, as 5 min Apgar score increased from 0 to 10, mortality decreased from 60% to 8%. However, no clear increasing or decreasing pattern was identified for SNI. There was an increase in sensitivity and decrease in specificity for both mortality and SNI associated with increasing scores. The Apgar score alone had an area under the curve of 0.64 for predicting mortality, which increased to 0.73 with the addition of gestational age. CONCLUSIONS: In neonates of 24-28 weeks' gestation admitted to neonatal units, higher 5 min Apgar score was associated with lower mortality in a graded manner, while the association with SNI remained relatively constant at all scores. Among survivors, low Apgar scores did not predict SNI.
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| 61. |
- Shah, Prakesh S., et al.
(author)
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Neonatal Outcomes of Very Low Birth Weight and Very Preterm Neonates : An International Comparison
- 2016
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In: Journal of Pediatrics. - : Elsevier BV. - 0022-3476 .- 1097-6833. ; 177, s. 144-152
-
Journal article (peer-reviewed)abstract
- Objective: To compare rates of a composite outcome of mortality or major morbidity in very-preterm/very low birth weight infants between 8 members of the International Network for Evaluating Outcomes.Study design: We included 58 004 infants born weighing < 1500 g at 24 degrees-31(6) weeks' gestation from databases in Australia/New Zealand, Canada, Israel, Japan, Spain, Sweden, Switzerland, and the United Kingdom. We compared a composite outcome (mortality or any of grade >= 3 peri-intraventricular hemorrhage, periventricular echodensity/echolucency, bronchopulmonary dysplasia, or treated retinopathy of prematurity) between each country and all others by using standardized ratios and pairwise using logistic regression analyses.Results: Despite differences in population coverage, included neonates were similar at baseline. Composite outcome rates varied from 26% to 42%. The overall mortality rate before discharge was 10% (range: 5% [Japan]-17% [Spain]). The standardized ratio (99% CIs) estimates for the composite outcome were significantly greater for Spain 1.09 (1.04-1.14) and the United Kingdom 1.16 (1.11-1.21), lower for Australia/New Zealand 0.93 (0.89-0.97), Japan 0.89 (0.86-0.93), Sweden 0.81 (0.73-0.90), and Switzerland 0.77 (0.69-0.87), and nonsignificant for Canada 1.04 (0.99-1.09) and Israel 1.00 (0.93-1.07). The adjusted odds of the composite outcome varied significantly in pairwise comparisons.Conclusions: We identified marked variations in neonatal outcomes between countries. Further collaboration and exploration is needed to reduce variations in population coverage, data collection, and case definitions. The goal would be to identify carepractices and health care organizational factors, which has the potential to improve neonatal outcomes.
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| 62. |
- Shah, Prakesh S., et al.
(author)
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The International Network for Evaluating Outcomes of very low birth weight, very preterm neonates (iNeo) : a protocol for collaborative comparisons of international health services for quality improvement in neonatal care
- 2014
-
In: BMC Pediatrics. - : Springer Science and Business Media LLC. - 1471-2431. ; 14, s. 110-
-
Journal article (peer-reviewed)abstract
- Background: The International Network for Evaluating Outcomes in Neonates (iNeo) is a collaboration of population-based national neonatal networks including Australia and New Zealand, Canada, Israel, Japan, Spain, Sweden, Switzerland, and the UK. The aim of iNeo is to provide a platform for comparative evaluation of outcomes of very preterm and very low birth weight neonates at the national, site, and individual level to generate evidence for improvement of outcomes in these infants. Methods/design: Individual-level data from each iNeo network will be used for comparative analysis of neonatal outcomes between networks. Variations in outcomes will be identified and disseminated to generate hypotheses regarding factors impacting outcome variation. Detailed information on physical and environmental factors, human and resource factors, and processes of care will be collected from network sites, and tested for association with neonatal outcomes. Subsequently, changes in identified practices that may influence the variations in outcomes will be implemented and evaluated using quality improvement methods. Discussion: The evidence obtained using the iNeo platform will enable clinical teams from member networks to identify, implement, and evaluate practice and service provision changes aimed at improving the care and outcomes of very low birth weight and very preterm infants within their respective countries. The knowledge generated will be available worldwide with a likely global impact.
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| 63. |
- Shahroor, Maher, et al.
(author)
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Unit-Level Variations in Healthcare Professionals' Availability for Preterm Neonates < 29 Weeks' Gestation : An International Survey
- 2019
-
In: Neonatology. - : S. Karger. - 1661-7800 .- 1661-7819. ; 116:4, s. 347-355
-
Journal article (peer-reviewed)abstract
- Introduction: The availability of and variability in healthcare professionals in neonatal units in different countries has not been well characterized. Our objective was to identify variations in the healthcare professionals for preterm neonates in 10 national or regional neonatal networks participating in the International Network for Evaluating Outcomes (iNeo) of neonates.Method: Online, pre-piloted questionnaires about the availability of healthcare professionals were sent to the directors of 390 tertiary neonatal units in 10 international networks: Australia/New Zealand, Canada, Finland, Illinois, Israel, Japan, Spain, Sweden, Switzerland, and Tuscany.Results: Overall, 325 of 390 units (83%) responded. About half of the units (48%; 156/325) cared for 11-30 neonates/day and had team-based (43%; 138/325) care models. Neonatologists were present 24 h a day in 59% of the units (191/325), junior doctors in 60% (194/325), and nurse practitioners in 36% (116/325). A nurse-to-patient ratio of 1:1 for infants who are unstable and require complex care was used in 52% of the units (170/325), whereas a ratio of 1:1 or 1:2 for neonates requiring multisystem support was available in 59% (192/325) of the units. Availability of a respiratory therapist (15%, 49/325), pharmacist (40%, 130/325), dietitian (34%, 112/325), social worker (81%, 263/325), lactation consultant (45%, 146/325), parent buddy (6%, 19/325), or parents' resource personnel (11%, 34/325) were widely variable between units.Conclusions: We identified variability in the availability and organization of the healthcare professionals between and within countries for the care of extremely preterm neonates. Further research is needed to associate healthcare workers' availability and outcomes. (C) 2019 S. Karger AG, Basel
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| 64. |
- Stephan, Ute, et al.
(author)
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Agility or Wait-and-See? : How the Covid-19 Crisis Impacts Entrepreneurs’ Well-being across Countries
- 2021
-
In: Academy of management annual meeting proceedings. - Briarcliff Manor, NY, USA : Academy of Management.
-
Conference paper (other academic/artistic)abstract
- We study how entrepreneurs and their well-being are impacted by crises and which entrepreneurs are able to safeguard their well-being. We examine the impact of the Covid-19 pandemic in a multilevel study of 3,149 entrepreneurs from 20 countries and draw attention to entrepreneur agility (flexible and adaptive action) both as a crisis response strategy and as a possible way for entrepreneurs to protect their well-being. We find that agile entrepreneurs, especially those that recognized new opportunities for their business in the pandemic, had better well-being during the pandemic (life satisfaction and vitality). Our findings offer further insights into agility as a response to adversity and whether it is enabled by cultural contexts supporting agility and entrepreneurs? human capital.
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| 65. |
- Sugahara, Yuma, et al.
(author)
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Big Three Dragons : A [N ii] 122 μm Constraint and New Dust-continuum Detection of a z = 7.15 Bright Lyman-break Galaxy with ALMA
- 2021
-
In: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 923:1
-
Journal article (peer-reviewed)abstract
- We present new Atacama Large Millimeter/submillimeter Array Band 7 observational results of a Lyman-break galaxy at z = 7.15, B14-65666 ("Big Three Dragons"), which is an object detected in [O iii] 88 μm, [C ii] 158 μm, and dust continuum emission during the epoch of reionization. Our targets are the [N ii] 122 μm fine-structure emission line and the underlying 120 μm dust continuum. The dust continuum is detected with a ∼19σ significance. From far-infrared spectral energy distribution sampled at 90, 120, and 160 μm, we obtain a best-fit dust temperature of 40 K (79 K) and an infrared luminosity of (12.1) at the emissivity index β = 2.0 (1.0). The [N ii] 122 μm line is not detected. The 3σ upper limit of the [N ii] luminosity is 8.1 × 107 L⊙. From the [N ii], [O iii], and [C ii] line luminosities, we use the Cloudy photoionization code to estimate nebular parameters as functions of metallicity. If the metallicity of the galaxy is high (Z > 0.4 Z⊙), the ionization parameter and hydrogen density are and nH ≃ 50–250 cm−3, respectively, which are comparable to those measured in low-redshift galaxies. The nitrogen-to-oxygen abundance ratio, N/O, is constrained to be subsolar. At Z < 0.4 Z⊙, the allowed U drastically increases as the assumed metallicity decreases. For high ionization parameters, the N/O constraint becomes weak. Finally, our Cloudy models predict the location of B14-65666 on the BPT diagram, thereby allowing a comparison with low-redshift galaxies.
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| 66. |
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| 67. |
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| 68. |
- Tokuoka, Tsuyoshi, et al.
(author)
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Possible Systematic Rotation in the Mature Stellar Population of a z=9.1 Galaxy
- 2022
-
In: Astrophysical Journal Letters. - : Institute of Physics Publishing (IOPP). - 2041-8205 .- 2041-8213. ; 933:1
-
Journal article (peer-reviewed)abstract
- We present new observations with the Atacama Large Millimeter/submillimeter Array for a gravitationally lensed galaxy at z = 9.1, MACS1149-JD1. [O III] 88 mu m emission is detected at 10 sigma with a spatial resolution of similar to 0.3 kpc in the source plane, enabling the most distant morphokinematic study of a galaxy. The [O iii] emission is distributed smoothly without any resolved clumps and shows a clear velocity gradient with Delta V-obs/2 sigma(tot) = 0.84 +/- 0.23, where Delta V-obs is the observed maximum velocity difference and sigma(tot) is the velocity dispersion measured in the spatially integrated line profile, suggesting a rotating system. Assuming a geometrically thin self-gravitating rotation disk model, we obtain V-rot/sigma(V)=0.67-0.26+0.73, where V-rot and sigma (V) are the rotation velocity and velocity dispersion, respectively, still consistent with rotation. The resulting disk mass of 0.65-0.40+1.37x10(9) M-circle dot is consistent with being associated with the stellar mass identified with a 300 Myr old stellar population independently indicated by a Balmer break in the spectral energy distribution. We conclude that the most of the dynamical mass is associated with the previously identified mature stellar population that formed at z similar to 15.
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| 69. |
- Ura, Ryota, et al.
(author)
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Detections of [C ii] 158 mu m and [O iii] 88 mu m in a Local Lyman Continuum Emitter, Mrk 54, and Its Implications to High-redshift ALMA Studies*
- 2023
-
In: Astrophysical Journal. - : Institute of Physics Publishing (IOPP). - 0004-637X .- 1538-4357. ; 948:1
-
Journal article (peer-reviewed)abstract
- We present integral field, far-infrared (FIR) spectroscopy of Mrk 54, a local Lyman continuum emitter, obtained with FIFI-LS on the Stratospheric Observatory for Infrared Astronomy. This is only the second time, after Haro 11, that [C ii] 158 mu m and [O iii] 88 mu m spectroscopy of the known LCEs have been obtained. We find that Mrk 54 has a strong [C ii] emission that accounts for similar to 1% of the total FIR luminosity, whereas it has only moderate [O iii] emission, resulting in the low [O iii]/[C ii] luminosity ratio of 0.22 +/- 0.06. In order to investigate whether [O iii]/[C ii] is a useful tracer of f (esc) (LyC escape fraction), we examine the correlations of [O iii]/[C ii] and (i) the optical line ratio of O-32 equivalent to [O iii] 5007 angstrom/[O ii] 3727 angstrom, (ii) specific star formation rate, (iii) [O iii] 88 mu m/[O i] 63 mu m ratio, (iv) gas-phase metallicity, and (v) dust temperature based on a combined sample of Mrk 54 and the literature data from the Herschel Dwarf Galaxy Survey and the LITTLE THINGS Survey. We find that galaxies with high [O iii]/[C ii] luminosity ratios could be the result of high ionization (traced by O-32), bursty star formation, high ionized-to-neutral gas volume filling factors (traced by [O iii] 88 mu m/[O i] 63 mu m), and low gas-phase metallicities, which is in agreement with theoretical predictions. We present an empirical relation between the [O iii]/[C ii] ratio and f (esc) based on the combination of the [O iii]/[C ii] and O-32 correlation, and the known relation between O-32 and f (esc). The relation implies that high-redshift galaxies with high [O iii]/[C ii] ratios revealed by the Atacama Large Millimeter/submillimeter Array may have f (esc) greater than or similar to 0.1, significantly contributing to the cosmic reionization.
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| 70. |
- Yamanaka, Satoshi, et al.
(author)
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Testing an indirect method for identifying galaxies with high levels of Lyman continuum leakage
- 2020
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In: Monthly notices of the Royal Astronomical Society. - : OXFORD UNIV PRESS. - 0035-8711 .- 1365-2966. ; 498:3, s. 3095-3114
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Journal article (peer-reviewed)abstract
- Using a sample of galaxies at z approximate to 3 with detected Lyman Continuum (LyC) leakage in the SSA22 field, we attempt to verify a proposed indirect method for identifying cases with high LyC escape fraction f(esc) based on measurements of the H beta equivalent width (EW) and the beta slope of the UV continuum. To this end, we present Keck/MOSFIRE H beta emission line flux measurements of LyC galaxies (LCGs) at spectroscopic redshifts z(spec) similar to 3.3, Lyman break galaxies (LBGs) at photometric redshifts z(phot) = 2.7-3.7, and Ly alpha emitters at z(phot) = 3.1. We also reconfirm the spectroscopic redshifts and measure the H beta emission-line fluxes from two LCGs and six LBGs. For the LCG in our sample with the most extreme f(esc), as revealed by the direct detection of LyC photons, we find that the EW(H beta)-beta method gives a broadly consistent estimate for f(esc), although the error bars remain very large. We also discuss how a combination of f(esc) measurements based on direct and indirect methods can shed light on the LyC escape mechanism and the anisotropy of the leakage.
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