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Träfflista för sökning "WFRF:(St. George Scott) "

Search: WFRF:(St. George Scott)

  • Result 51-100 of 403
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51.
  • Middeldorp, Christel M., et al. (author)
  • The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia : design, results and future prospects
  • 2019
  • In: European Journal of Epidemiology. - : Springer Science and Business Media LLC. - 0393-2990 .- 1573-7284. ; 34:3, s. 279-300
  • Journal article (peer-reviewed)abstract
    • The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and disorders may therefore provide new perspectives, not only on how to improve wellbeing during childhood, but also how to prevent later adverse outcomes. To achieve the sample sizes required for genetic research, the Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia were established. The majority of the participating cohorts are longitudinal population-based samples, but other cohorts with data on early childhood phenotypes are also involved. Cohorts often have a broad focus and collect(ed) data on various somatic and psychiatric traits as well as environmental factors. Genetic variants have been successfully identified for multiple traits, for example, birth weight, atopic dermatitis, childhood BMI, allergic sensitization, and pubertal growth. Furthermore, the results have shown that genetic factors also partly underlie the association with adult traits. As sample sizes are still increasing, it is expected that future analyses will identify additional variants. This, in combination with the development of innovative statistical methods, will provide detailed insight on the mechanisms underlying the transition from childhood to adult disorders. Both consortia welcome new collaborations. Policies and contact details are available from the corresponding authors of this manuscript and/or the consortium websites.
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52.
  • Scott, Robert A., et al. (author)
  • Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
  • 2012
  • In: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 44:9, s. 991-1005
  • Journal article (peer-reviewed)abstract
    • Through genome-wide association meta-analyses of up to 133,010 individuals of European ancestry without diabetes, including individuals newly genotyped using the Metabochip, we have increased the number of confirmed loci influencing glycemic traits to 53, of which 33 also increase type 2 diabetes risk (q < 0.05). Loci influencing fasting insulin concentration showed association with lipid levels and fat distribution, suggesting impact on insulin resistance. Gene-based analyses identified further biologically plausible loci, suggesting that additional loci beyond those reaching genome-wide significance are likely to represent real associations. This conclusion is supported by an excess of directionally consistent and nominally significant signals between discovery and follow-up studies. Functional analysis of these newly discovered loci will further improve our understanding of glycemic control.
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53.
  • Aad, G., et al. (author)
  • 2014
  • Journal article (peer-reviewed)
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54.
  • Aad, G., et al. (author)
  • 2011
  • swepub:Mat__t (peer-reviewed)
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55.
  • Aad, G., et al. (author)
  • 2011
  • Journal article (peer-reviewed)
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56.
  • Aad, G., et al. (author)
  • 2012
  • swepub:Mat__t (peer-reviewed)
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57.
  • Aad, G., et al. (author)
  • 2012
  • swepub:Mat__t (peer-reviewed)
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58.
  • Aad, G., et al. (author)
  • 2011
  • swepub:Mat__t (peer-reviewed)
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59.
  • Aad, G., et al. (author)
  • 2014
  • In: Physical Review C (Nuclear Physics). - 0556-2813 .- 1089-490X. ; 90:4
  • Journal article (peer-reviewed)
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60.
  • Aad, G., et al. (author)
  • 2013
  • swepub:Mat__t (peer-reviewed)
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61.
  • Aad, G., et al. (author)
  • 2013
  • Journal article (peer-reviewed)
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62.
  • Aad, G., et al. (author)
  • 2013
  • In: New Journal of Physics. - : IOP Publishing. - 1367-2630. ; 15
  • Journal article (peer-reviewed)
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63.
  • Aad, G., et al. (author)
  • 2014
  • In: The European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6052. ; 74:8
  • Journal article (peer-reviewed)
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64.
  • Aad, G., et al. (author)
  • 2012
  • swepub:Mat__t (peer-reviewed)
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65.
  • Aad, G., et al. (author)
  • 2012
  • swepub:Mat__t (peer-reviewed)
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66.
  • Aad, G., et al. (author)
  • 2012
  • swepub:Mat__t (peer-reviewed)
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67.
  • Aad, G., et al. (author)
  • 2012
  • swepub:Mat__t (peer-reviewed)
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68.
  • Aad, G., et al. (author)
  • 2013
  • Journal article (peer-reviewed)
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69.
  • Aad, G., et al. (author)
  • 2012
  • swepub:Mat__t (peer-reviewed)
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70.
  • Aad, G., et al. (author)
  • 2012
  • swepub:Mat__t (peer-reviewed)
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71.
  • Aad, G., et al. (author)
  • 2012
  • swepub:Mat__t (peer-reviewed)
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72.
  • Aad, G., et al. (author)
  • 2012
  • swepub:Mat__t (peer-reviewed)
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73.
  • Aad, G., et al. (author)
  • 2012
  • swepub:Mat__t (peer-reviewed)
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74.
  • Aad, G., et al. (author)
  • 2013
  • In: The European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6052. ; 73:1
  • Journal article (peer-reviewed)
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75.
  • Aad, G., et al. (author)
  • 2015
  • Journal article (peer-reviewed)
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76.
  • Aad, G., et al. (author)
  • 2013
  • Journal article (peer-reviewed)
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77.
  • Aad, G., et al. (author)
  • 2015
  • Journal article (peer-reviewed)
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78.
  • Aad, G., et al. (author)
  • 2013
  • Journal article (peer-reviewed)
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79.
  • Aad, G., et al. (author)
  • 2014
  • Journal article (peer-reviewed)
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80.
  • Aad, G., et al. (author)
  • 2013
  • Journal article (peer-reviewed)
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81.
  • Aad, G., et al. (author)
  • 2013
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82.
  • Aad, G., et al. (author)
  • 2012
  • swepub:Mat__t (peer-reviewed)
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83.
  • Aad, G., et al. (author)
  • 2012
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84.
  • Aad, G., et al. (author)
  • 2013
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85.
  • Aad, G., et al. (author)
  • 2011
  • swepub:Mat__t (peer-reviewed)
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86.
  • Aad, G., et al. (author)
  • 2011
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87.
  • Aad, G., et al. (author)
  • 2012
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88.
  • Aad, G., et al. (author)
  • 2011
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89.
  • Aad, G., et al. (author)
  • 2012
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90.
  • Aad, G., et al. (author)
  • 2012
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91.
  • Aad, G., et al. (author)
  • 2012
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92.
  • Aad, G., et al. (author)
  • 2012
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93.
  • Aad, G., et al. (author)
  • 2014
  • In: The European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6052. ; 74:6
  • Journal article (peer-reviewed)
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94.
  • Aad, G., et al. (author)
  • 2012
  • swepub:Mat__t (peer-reviewed)
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95.
  • Aad, G., et al. (author)
  • 2012
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96.
  • Aad, G., et al. (author)
  • 2014
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97.
  • Aad, G., et al. (author)
  • 2013
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98.
  • Aad, G., et al. (author)
  • 2012
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99.
  • Aad, G., et al. (author)
  • 2012
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100.
  • Aad, G., et al. (author)
  • 2014
  • In: The European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6052. ; 74:10
  • Journal article (peer-reviewed)
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  • Result 51-100 of 403
Type of publication
journal article (269)
research review (1)
Type of content
peer-reviewed (387)
other academic/artistic (2)
Author/Editor
Arai, Y. (375)
Abi, B. (374)
Abramowicz, H. (374)
Adelman, J. (374)
Adye, T. (374)
Aleksa, M. (374)
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Alexandre, G. (374)
Amelung, C. (374)
Anastopoulos, C. (374)
Antonaki, A. (374)
Antonelli, M. (374)
Arguin, J-F. (374)
Arnaez, O. (374)
Asquith, L. (374)
Assamagan, K. (374)
Azuma, Y. (374)
Bachacou, H. (374)
Bachas, K. (374)
Backes, M. (374)
Baker, O. K. (374)
Banas, E. (374)
Barisonzi, M. (374)
Barklow, T. (374)
Beau, T. (374)
Beck, H. P. (374)
Bella, G. (374)
Beltramello, O. (374)
Benary, O. (374)
Benekos, N. (374)
Benhammou, Y. (374)
Bentvelsen, S. (374)
Beringer, J. (374)
Berry, T. (374)
Biesiada, J. (374)
Bilokon, H. (374)
Blumenschein, U. (374)
Boehler, M. (374)
Boisvert, V. (374)
Boonekamp, M. (374)
Borisov, A. (374)
Borissov, G. (374)
Boyd, J. (374)
Bulekov, O. (374)
Burckhart, H. (374)
Burke, S. (374)
Busato, E. (374)
Butler, B. (374)
Calderini, G. (374)
Cameron, D. (374)
Carli, T. (374)
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University
Lund University (239)
Stockholm University (233)
Uppsala University (231)
Royal Institute of Technology (226)
Karolinska Institutet (13)
University of Gothenburg (7)
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Umeå University (3)
Mid Sweden University (2)
Halmstad University (1)
Örebro University (1)
Linköping University (1)
Stockholm School of Economics (1)
Chalmers University of Technology (1)
Swedish University of Agricultural Sciences (1)
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Language
English (403)
Research subject (UKÄ/SCB)
Natural sciences (241)
Medical and Health Sciences (12)
Humanities (1)

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