| 1. |
- Eliasson, Karolina
(författare)
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A case-based approach to dialogue systems
- 2010
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Ingår i: Journal of experimental and theoretical artificial intelligence (Print). - : Taylor & Francis. - 0952-813X .- 1362-3079. ; 22:1, s. 23-51
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Tidskriftsartikel (refereegranskat)abstract
- We describe an approach to integrate dialogue management, machine-learning and action planning in a system for dialogue between a human and a robot. Case-based techniques are used because they permit life-long learning from experience and demand little prior knowledge and few static hand-written structures. This approach has been developed through the work on an experimental dialogue system, called CEDERIC, that is connected to an unmanned aerial vehicle (UAV). A single case base and case-based reasoning engine is used both for understanding and for planning actions by the UAV. Dialogue experiments both with experienced and novice users, where the users have solved tasks by dialogue with this system, showed very adequate success rates.
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| 2. |
- Gurvich, Olga L, et al.
(författare)
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Two groups of phenylalanine biosynthetic operon leader peptides genes : a high level of apparently incidental frameshifting in decoding Escherichia coli pheL
- 2011
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Ingår i: Nucleic Acids Research. - : Oxford University Press (OUP). - 0305-1048 .- 1362-4962. ; 39:8, s. 3079-3092
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Tidskriftsartikel (refereegranskat)abstract
- The bacterial pheL gene encodes the leader peptide for the phenylalanine biosynthetic operon. Translation of pheL mRNA controls transcription attenuation and, consequently, expression of the downstream pheA gene. Fifty-three unique pheL genes have been identified in sequenced genomes of the gamma subdivision. There are two groups of pheL genes, both of which are short and contain a run(s) of phenylalanine codons at an internal position. One group is somewhat diverse and features different termination and 5’-flanking codons. The other group, mostly restricted to Enterobacteria and including Escherichia coli pheL, has a conserved nucleotide sequence that ends with UUC_CCC_UGA. When these three codons in E. coli pheL mRNA are in the ribosomal E-, P- and A-sites, there is an unusually high level, 15%, of +1 ribosomal frameshifting due to features of the nascent peptide sequence that include the penultimate phenylalanine. This level increases to 60% with a natural, heterologous, nascent peptide stimulator. Nevertheless, studies with different tRNA(Pro) mutants in Salmonella enterica suggest that frameshifting at the end of pheL does not influence expression of the downstream pheA. This finding of incidental, rather than utilized, frameshifting is cautionary for other studies of programmed frameshifting.
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