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- Grabau, Dorthe
(författare)
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Breast cancer patients with micrometastases only: Is a basis provided for tailored treatment?
- 2008
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Ingår i: Surgical Oncology. - : Elsevier BV. - 0960-7404. ; 17, s. 211-217
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Tidskriftsartikel (refereegranskat)abstract
- Women with breast cancer and micrometastases only constitute a treatment dilemma. If only a micrometastasis is found in a sentinel lymph node, an axillary lymph node dissection may be considered to be overtreatment and perhaps could be avoided. However, studies have shown decreased survival in patients with micrometastases only. This paper focuses on the pathological work-up behind the classification of breast cancer patients having micrometastases only and on the most recent literature concerning prognosis for breast cancer patients with micrometastases. The goal was to determine if studies to date have been able to define a population of breast cancer patients with micrometastases where the size of the metastasis could indicate whether an axillary lymph node dissection should be undertaken. Tailored surgical treatment of breast cancer patients with micrometastases only is not possible at the present time, due to lack of standardization in the pathological work-up of lymph nodes, which implies that this group of breast cancer patients cannot be delimited with sufficient precision. Tailored systemic therapy is also impossible due to lack of a precisely defined target for a feasible therapy.
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| 3. |
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| 4. |
- Naredi, Peter, 1955, et al.
(författare)
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Why do we need a core curriculum in surgical oncology in Europe?
- 2008
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Ingår i: Surgical oncology. - 0960-7404. ; 17:4, s. 267-9
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Tidskriftsartikel (refereegranskat)abstract
- Patients with cancer are often treated by multidisciplinary collaboration between many specialities where thorough knowledge about cancer, and surgical expertise is necessary. Most European surgeons with an interest in surgical oncology were trained according to their local organisations and national regulations. Formal education as per a national training programme is rare and little collaborative effort has taken place within Europe to standardize training between the relevant national surgical societies. The outcome measure of completion of training is vague. Surgical oncology is at present only recognised by a few European countries. Training in surgical oncology has been guided by tradition and common sense rather than by specific aims within the framework of a recognised internationally established core curriculum. Any educational initiative has to be delivered during restricted working hours as determined by European regulation. Accordingly, the actual number of surgical procedures that each trainee will perform under supervision is limited. A modern core curriculum necessitates an evidence-based approach, rather than common sense medicine.
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