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| 2. |
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| 3. |
- Akner, Gunnar, 1953-, et al.
(författare)
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Adrenocorticotropin and cortisol response to lysine vasopressin in relation to the outcome of the dexamethasone suppression test in major depressive disorder
- 1988
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Ingår i: Acta Psychiatrica Scandinavica. - : Wiley. - 0001-690X .- 1600-0447. ; 77:4, s. 404-410
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Tidskriftsartikel (refereegranskat)abstract
- The pathophysiology behind the abnormalities of the hypothalamic pituitary adrenal cortex axis found in patients with major depressive disorder was studied by the use of the vasopressin test. The response of plasma adrenocorticotropin (ACTH) and cortisol to the injection of 10 IU lysine-vasopressin (LVP) was investigated in 18 patients meeting the DSM-III criteria for major depressive episode. The response was correlated to the outcome of the dexamethasone suppression test (DST) with the use of two different cut-off points, 139 nmol/l and 200 nmol/l respectively. The results show that no significant difference was found in ACTH or cortisol response between patients having a normal or abnormal DST. The results do not seem to support the hypothesis that the abnormalities of the hypothalamic pituitary adrenal cortex axis involve a hypersecretion of corticotropin-releasing factor (CRF) and a subsequent desensitization of the corticotrophs to CRF-stimulated ACTH release.
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| 4. |
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| 5. |
- Akner, Gunnar, 1953-, et al.
(författare)
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Intramuscular ceruletide does not affect food intake in obese and non-obese human subjects
- 1985
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Ingår i: Appetite. - : Elsevier BV. - 0195-6663 .- 1095-8304. ; 6:1, s. 21-24
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Tidskriftsartikel (refereegranskat)abstract
- Intramuscular ceruletide or placebo was given in a randomized double-blind crossover design to 12 non-obese and 12 obese individuals, 30 min before a palatable lunch meal. No significant effects were found on the amount of food intake or the hunger ratings in any group. Although rapid CCK or ceruletide infusions have been found in some studies to reduce food intake in man and animals, slow infusions have increased food intake. Under the present study conditions, the moderate rate of release of ceruletide from intramuscular depots did not affect the food intake.
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| 6. |
- Andersson, Anne-Marie, et al.
(författare)
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LvU-utredningar : kritisk granskning och utveckling
- 1984
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Syftet är att utveckla en problemfokuserad arbetsmodell för LVU-utredningar. Åtta utredningar efter 82-01-01 granskades och fem kunniga informanter som representerade olika perspektiv intervjuades om LVU-utredande. De granskade utredningarna bedömdes uppvisa brister. En perspektiv- och problemfokuserad arbetsmodell framläggs.
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| 7. |
- Andrén, O., et al.
(författare)
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Barley straw decomposition with varied levels of microbial grazing by Folsomia fimetaria (L.) (Collembola, Isotomidae)
- 1985
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Ingår i: Oecologia. - : Springer-Verlag New York. - 0029-8549 .- 1432-1939. ; 68:1, s. 57-62
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Tidskriftsartikel (refereegranskat)abstract
- Folsomia fimetaria (L.) were added (0, 5, 10, 20 animals) to 0.100 g barley straw which had been inoculated 10 days (244 h) earlier with a natural soil microflora. Respiration (CO2 evolution) was monitored continuously. Mass loss, fungal standing crop (total and FDA-active), bacterial and protozoan biomass were estimated 42 days (1,000 h) after microbial inoculation. The degree of surface cover by hyphae was surveyed at regular intervals. No significant differences (P>0.05) were found in respiration, mass loss or microbial biomass, but the density of surface hyphae were reduced by addition of Collembola. Fungal production was low, less than 5% of the estimated microbial production, and could not account for all collembolan growth during incubation. F. fimetaria appeared to consume mainly bacteria and protozoa, and had little impact on carbon mineralization.
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| 8. |
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| 9. |
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| 10. |
- Ashman, J, et al.
(författare)
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Exclusive ρ0 and Φ production in deep inelastic muon scattering
- 1988
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Ingår i: Zeitschrift für Physik C Particles and Fields. - New York, USA : Springer. - 0170-9739 .- 1431-5858. ; 39:2, s. 169-175
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Tidskriftsartikel (refereegranskat)abstract
- Data are presented on exclusive ρ0 and φ{symbol} production in deep inelastic muon scattering from a target consisting mainly of nitrogen. The ratio of the total cross sections for ρ0 and φ{symbol} production is found to be 9:(1.6±0.4) at 〈Q2〉=7.5 GeV2, consistent with the SU(3) prediction of 9:2. The t dependence for exclusive ρ0 production is found to become shallover as Q2 increases and, for large Q2, the t dependence is typical of that for a hard scattering process. Furthermore, the ratio of the cross sections for coherent: incoherent production from nitrogen is found to decrease rapidly with Q2. Such behaviour indicates that even for exclusive vector meson production the virtual photon behaves predominantly as an electromagnetic probe.
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| 11. |
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| 12. |
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| 13. |
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| 14. |
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| 15. |
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| 16. |
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| 17. |
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| 18. |
- Bergqvist, Åsa, et al.
(författare)
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Smittspridning av campylobacter inom fjäderfäslakteri
- 1986
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Ingår i: XV Nordiska veterinärkongressen – 15th Nordic Veterinary Congress, Stockholm 28/7–1/8 1986. - Stockholm : Sveriges Veterinärförbund. - 9178106435 ; , s. 355-358
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Konferensbidrag (refereegranskat)
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| 19. |
- Berndtson, Eva, et al.
(författare)
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Incidence of campylobacter on a broiler farm
- 1987
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Ingår i: The IVth International Workshop on Campylobacter Infections, Department of Clinical Bacteriology, University Göteborg, June 16–18, 1987, Göteborg, Sweden. ; , s. Abstract no. 17-
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Konferensbidrag (refereegranskat)
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| 20. |
- Boija, Per Olov, et al.
(författare)
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Hypovolaemic stress induced glycogenolysis, isolated liver perfusion study
- 1987
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Ingår i: Research in experimental medicine. - : Springer. - 0300-9130 .- 1433-8580. ; 187:5, s. 315-322
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Tidskriftsartikel (refereegranskat)abstract
- Intrinsic hepatic glycogenolysis was examined after hypovolemic stress. Hemorrhagic hypotension of 70 (P70) and 40 mm Hg (P40) for 60 min was inflicted for two postprandial groups and of 70 mm Hg (S70) in a 24-h starved group. The results were compared with three control groups; one postprandial (Pc), one 24-h starved (Sc), and one starved for 9 h (Sc: 9) to mimic the glycogen depletion produced by 70 mm Hg hemorrhagic hypotension. Glucose output was studied in vitro using av recirculating isolated liver perfusion system with a perfusate free of glucose and endocrine stimulation. Liver glycogen determination was made before perfusion start. Although the glycogen stores were decreased after hemorrhage glucose yield was increased (P70) and unchanged (P40) as compared to controls (Pc and Sc: 9). Both starved groups delivered small amounts of glucose, but the released fraction of the S70 group was more than twice that from the Sc group. These data suggest a liver enzyme activation with increased velocity of the enzymesubstrate reactions responsible for glycogen degradation, induced during in vivo hemorrhage and persisting for at least 30 min in vitro perfusion.
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| 21. |
- Bonde, Torben A., et al.
(författare)
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Microbial biomass as a fraction of potentially mineralizable nitrogen in soils from long-term field experiments
- 1988
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Ingår i: Soil Biology and Biochemistry. - : Elsevier. - 0038-0717 .- 1879-3428. ; 20:4, s. 447-452
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Tidskriftsartikel (refereegranskat)abstract
- Aerobic long-term incubations (40-wk) were employed to measure the potentially mineralizable nitrogen (N0) in five 30-yr old cropping systems. The cropping systems consisted of: (1) bare fallow; (2) cropping with no additions; (3) cropping with 80 kg N ha-1 y-1 as Ca(NO3)2; (4) cropping with 80 kg N ha-1 yr-1 as Ca(NO3)2 plus 1800kg C ha-1 yr-1 as straw; and (5) cropping with 80 kg N ha-1 yr-1 plus 1800 kg C ha-1 yr-1 as farmyard manure. The amounts of N mineralized during the 40-wk incubations were between 93 and 168 μg g-1 (302-543 kg N ha-1 down to 25cm depth) with the lowest value for the fallow and the highest for the farmyard manure treatment. Microbial biomass-C and -N were measured on four occasions during the incubations. The biomass-C showed a rapid decrease to week 4 (to 36% of the initial mass), a slower decrease to week 9 (to 23% of initial mass) and a very slow decline to the final determination at the end of the incubation (to 8% of initial mass). The biomass-N displayed a similar pattern. Two related models were employed to describe the kinetics of N-mineralization during incubation: (1) a two-component first-order; and (2) a simplified special case of the two-component model. In all cases except the straw-amended soil, the simplified two-component model offered the best description of the curves of accumulated mineral-N. The available fraction, Na, of soil organic-N had mineralization rate constants similar to those for mineralization of microbial biomass.
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| 22. |
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| 23. |
- Burgess, G.M., et al.
(författare)
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Further studies on the interactions between the calcium mobilization and cyclic AMP pathways in guinea pig hepatocytes
- 1986
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Ingår i: Molecular Pharmacology. - : American Society for Pharmacology and Experimental Therapeutics. - 0026-895X .- 1521-0111. ; 30:4, s. 315-320
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Tidskriftsartikel (refereegranskat)abstract
- Isoproterenol (50 nM) potentiated the effects of angiotensin (1-50 nM) on 86Rb efflux and 45Ca efflux from guinea pig hepatocytes. This effect occurred in the presence or absence of extracellular Ca2+ and required the simultaneous presence of both isoproterenol and angiotensin. Neither the divalent cationophore, A23187, nor 4 beta-phorbol dibutyrate could substitute for angiotensin. The effects of isoproterenol were greatest with submaximal concentrations of angiotensin, whereas maximal concentrations of angiotensin were affected little. Isoproterenol did not substantially increase the formation of [3H]inositol triphosphate or the ratio of isomers [3H]inositol 1,4,5-trisphosphate and [3H]inositol 1,3,4-trisphosphate formed in response to angiotensin. Isoproterenol also enhanced the phase of Ca2+ mobilization involving Ca2+ entry which is consistent with the previously proposed functional linkage between receptor-regulated Ca2+ release and Ca2+ entry. These findings suggest that isoproterenol may act by increasing the sensitivity of the endoplasmic reticulum to the Ca2+-releasing action of inositol 1,4,5-trisphosphate.
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| 24. |
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| 25. |
- Connolly, E, et al.
(författare)
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Na+-dependent, alpha-adrenergic mobilization of intracellular (mitochondrial) Ca2+ in brown adipocytes
- 1984
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Ingår i: European Journal of Biochemistry. - : Wiley. - 0014-2956 .- 1432-1033. ; 141:1, s. 187-193
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Tidskriftsartikel (refereegranskat)abstract
- The existence and significance of a hormone-sensitive, rapidly mobilizable intracellular pool of Ca2+ in hamster brown-fat cells was investigated with 45Ca2+-labelling techniques. It was shown that such a pool existed and was probably located within the abundant mitochondria. It was rapidly mobilized by norepinephrine (median effective concentration 50 nM) through alpha-adrenergic mechanisms. The mobilization of Ca2+ from the intracellular stores (mitochondria) required the presence of extracellular Na+, but not of Ca2+, K+ or Mg2+. It is concluded that the experiments are in agreement with a hypothesis linking the mobilization of intracellular Ca2+ pools with an alpha-adrenergically-induced increase in plasma membrane Na+ permeability (observed as a membrane depolarization), and a subsequent activation of the mitochondrial Na+/Ca2+ exchange, leading to mobilization of mitochondrial Ca2+ and the mediation of alpha-adrenergic effects as a result of an elevated cytosolic Ca2+ level.
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| 26. |
- Connolly, Eamonn, et al.
(författare)
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Norepinephrine-induced Na+ influx in brown adipocytes is cyclic AMP-mediated
- 1986
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Ingår i: Journal of Biological Chemistry. - : American Society for Biochemistry and Molecular Biology. - 0021-9258 .- 1083-351X. ; 261:31, s. 14377-14385
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Tidskriftsartikel (refereegranskat)abstract
- To examine the involvement of Na+ ions in adrenergic responses in brown adipose tissue, a method is described for measuring Na+ influx into isolated brown adipocytes, using short (30 s) incubations with 22Na+, followed by a two-step centrifugation recovery procedure. Using this method, a clear norepinephrine-stimulated accumulation of intracellular 22Na+ was observed, which was enhanced by the addition of ouabain, was insensitive to amiloride (a Na+/H+ exchange blocker), and could not be mimicked by the total removal of oxygen from the incubation medium. The norepinephrine-stimulated Na+ influx was dose-dependent for the hormone with an EC50 of 250 nM, was blocked by the beta-antagonist propranolol but not by the alpha 1-antagonist prazosin, and could be induced by adrenergic agonists with the order of potency: isoproterenol greater than norepinephrine greater than phenylephrine, indicating a beta-receptor-mediated process. The Na+ influx was found to be cAMP-dependent since it could be induced by both theophylline (a phosphodiesterase inhibitor) and forskolin (an adenylate cyclase activator), but it was independent of other known cellular cAMP-dependent responses since neither addition of fatty acid substrates (octanoate or palmitate), nor of the mitochondrial uncoupler carbonyl cyanide p-trifluoromethoxyphenyl-hydrazone could induce the phenomenon, despite having significant stimulatory effects on cellular respiration. Furthermore, total respiratory inhibition with rotenone, or total oxygen depletion of the medium with dithionite, did not prevent the normal norepinephrine-induced Na+ influx. The possibility that this beta-mediated norepinephrine-stimulated Na+ influx plays an important physiological role in brown adipose tissue activity is discussed, perhaps as one of the, as yet undefined, signals initiating tissue growth in the chronically beta-stimulated tissue of animals facing long-term increases in thermogenic demands.
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| 27. |
- Cyr, David, et al.
(författare)
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Case report: Meningioma
- 1988
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Ingår i: The Hearing Journal®. - 0745-7472. ; :Nov, s. 50-53
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Tidskriftsartikel (refereegranskat)
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| 28. |
- Cyr, David, et al.
(författare)
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Clinical experience with the low-frequency rotary chair test
- 1989
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Ingår i: Seminars in Hearing. - 0734-0451 .- 1098-8955. ; 10:2, s. 172-190
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Tidskriftsartikel (refereegranskat)abstract
- The primary strength of the CRC test appears to be its sensitivity to monitor change within the vestibular system, particularly in the early detection of a bilateral, peripheral weakness. Although disagreement continues about the low-frequency rotary chair's ability to monitor physiological compensation following a sudden, unilateral vestibular insult, some points are worth reviewing. For example, in an acute, unilateral vestibular weakness, an asymmetry will usually be present in the direction of the spontaneous nystagmus. In addition, gain may be depressed (primarily in the low frequencies) and a large phase lead should be seen.As central compensation occurs, the degree of asymmetry will reportedly decrease or resolve completely (probably secondary to a decrease in the spontaneous nystagmus), and gain may improve as well. In contrast, the low-frequency phase lead appears to persist in most patients. Recall that the symmetry measure is likely a representation of a spontaneous nystagmus or directional preponderance, whereas gain can be affected by patient alertness and other extravestibular factors during low-frequency acceleration. For these reasons, the clinical significance of gain and symmetry change following low-frequency rotation remains somewhat obscure. Because the rotary chair is extremely sensitive to bilateral, peripheral vestibular lesions, it seems ideal for monitoring the effects of vestibulotoxic medications. If patient alertness is maintained, both low-frequency phase and gain can be used to monitor vestibular change, as is illustrated in case study 1. Another effective application of the CRC test is its use with special populations, especially infants and young children in whom caloric testing cannot be done. The test is easy to administer, takes a minimal amount of time, and is not adversive to most patients, unless claustrophobia is present. Even though the low-frequency rotary chair test has specific limitations (such as inability to identify consistently site of lesion or side of involvement in unilateral, peripheral vestibular disease), it has demonstrated a significant clinical usefulness, as described previously. It must be stressed, however, that the CRC results should be treated with a degree of caution. Our knowledge of the visual and vestibular systems is limited, and the low-frequency CRC test monitors only a fraction of the VOR. We must take into account other fctors, such as the otolith organs, the other semicircular canals, the brainstem integration of the response, and the cognitive processes, such as prediction, that may also affect the rest results. As is appropriate with all clinical assessments, the rotary chair results should always be interpreted in light of the history, symptoms, and other test findings. Future advances in stimulus presentation and response measurement however, should solidify the role of the CRC test in the evaluation of the patient with dizziness.
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| 29. |
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| 30. |
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| 31. |
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| 32. |
- Danielsson Tham, Marie-Louise, 1947-, et al.
(författare)
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Bakteriella matförgiftningstoxiner
- 1989
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Ingår i: Vår Föda. - 0042-2681. ; 41:9–10, s. 446-453
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Tidskriftsartikel (refereegranskat)
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| 33. |
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| 34. |
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| 35. |
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| 36. |
- Danielsson Tham, Marie-Louise, 1947-
(författare)
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Bästa stutolog!
- 1989
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Ingår i: Bladmagen. ; 23:3, s. 86-86
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Tidskriftsartikel (populärvet., debatt m.m.)
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| 37. |
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| 38. |
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| 39. |
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| 40. |
- Danielsson-Tham, Marie-Louise, 1947-
(författare)
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Farligheter i födan : Aktuell livsmedelshygienisk forskning
- 1987
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Ingår i: Journalen. ; 7:4, s. 106-108
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- Artikeln bygger på ett föredrag som professor Marie-Louise Danielsson-Tham, institutionen för livsmedelshygien i Uppsala, höll vid Kvinnliga läkares förenings höstmöte 1986
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| 41. |
- Danielsson Tham, Marie-Louise, 1947-
(författare)
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Felciterat om bestrålning : DN Debatt
- 1989
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Ingår i: Dagens Nyheter. - 1101-2447. ; :2 april, s. 5-5
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Tidskriftsartikel (populärvet., debatt m.m.)
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| 42. |
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| 43. |
- Danielsson-Tham, Marie-Louise, 1947-, et al.
(författare)
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Getostens bakteriologi och hygien
- 1980
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Ingår i: Vår Föda. - Uppsala. - 0042-2681. ; 32, suppl 3, s. 1-277
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Tidskriftsartikel (refereegranskat)
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| 44. |
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| 45. |
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| 46. |
- Danielsson Tham, Marie-Louise, 1947-
(författare)
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I huvet på en livsmedelshygieniker
- 1988
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Ingår i: Livsmedelsteknik. - 0024-5399. ; :1–2, s. 8-9
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Tidskriftsartikel (populärvet., debatt m.m.)
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| 47. |
- Danielsson Tham, Marie-Louise, 1947-
(författare)
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Listeria, inte bara en ostbakterie
- 1988
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Ingår i: Stad och Land – Rapport. - 0280-4549. ; :3, s. 6-7
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Tidskriftsartikel (populärvet., debatt m.m.)
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| 48. |
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| 49. |
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| 50. |
- Danielsson-Tham, Marie-Louise, 1947-
(författare)
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Matförgiftningsrisker i mass-catering
- 1988
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Ingår i: Elintarvikehygienian päivät, The Association of the Finnish Veterinary Food Hygienists, Annual Meeting 17–19 of March, 1988, Laivaristeily, Helsinki, Tokholma, Helsinki. - Helsinki : The Association of the Finnish Veterinary Food Hygienists. ; , s. 45-49
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Konferensbidrag (refereegranskat)
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