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| 2. |
- Berglund, Svante, et al.
(författare)
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The ATLAS Tile Calorimeter Digitizer
- 1999
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Ingår i: 1999 IEEE Nuclear Science Symposium. ; 2, s. 760-764, s. 255-259
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 6. |
- Anders, Berntson, et al.
(författare)
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Power dependence and accessible bandwidth for dispersion-managed solitons in asymmetric dispersion maps
- 1998
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Ingår i: Electronics Letters. - Goteborg, Sweden : Institution of Engineering and Technology. - 0013-5194 .- 1350-911X. ; 34:21, s. 2054-2056
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Tidskriftsartikel (refereegranskat)abstract
- The authors investigate how the parameters of dispersion managed solitons depend on the asymmetry of the dispersion map. Using the variational approach and numerical simulations it is shown that asymmetric maps can increase the accessible bandwidth in the normal average dispersion regime and equalise the power in adjacent WDM channels.
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| 7. |
- Anderson, D, et al.
(författare)
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Analysis of profile effects on high Q subignited Tokamak fusion plasmas
- 1998
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Ingår i: PHYSICA SCRIPTA. - : ROYAL SWEDISH ACAD SCIENCES. - 0281-1847. ; 58:3, s. 256-261
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- An analysis is made of the maximum power multiplication factor Q, achievble in subignited Tokamak fusion plasmas where the burn is sustained by feedback controlled auxiliary heating. Using a 1-D model equation for the plasma temperature, simple analytical
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| 8. |
- Anderson, H, et al.
(författare)
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Blood transfusion at delivery and risk of subsequent malignant lymphoma in the mother
- 1998
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Ingår i: Vox Sanguinis. - 0042-9007. ; 75:2, s. 145-148
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND AND OBJECTIVES: Blood transfusion has been shown to be a risk factor for non-Hodgkin's lymphoma (NHL).MATERIALS AND METHODS: In a cohort of 77,928 women with bleeding complications at delivery in the period of 1973-1986, subsequent NHL cases were identified and the number was compared with the number expected from national incidence rates. In a case-control study the proportion of transfused NHL cases was compared with the proportion of transfused controls.RESULTS: The observed number of NHL in the cohort was 18 versus 22.0 expected. Information on transfusion was obtained for 15 of the NHL cases and none (0%) was transfused versus 32 out of 136 controls (23%).CONCLUSIONS: Blood transfusion at delivery is not a risk factor for NHL. The immune tolerance induced by pregnancy may reduce the risk of NHL associated with the transfusion of allogeneic blood cells.
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| 11. |
- Berglund, Svante, et al.
(författare)
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The ATLAS Tile Calorimeter Digitizer
- 1998
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Ingår i: Proceedings of the Fourth Workshop on Electronics for LHC Experiments. ; , s. 246-249
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 12. |
- Brandt, L, et al.
(författare)
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Blood transfusion as a risk factor for non-Hodgkin lymphoma
- 1996
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Ingår i: British Journal of Cancer. - 0007-0920. ; 73:9, s. 1148-1151
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Tidskriftsartikel (refereegranskat)abstract
- In a case-control study of 280 out of 426 consecutive patients with a recent diagnosis of non-Hodgkin lymphoma (NHL) and 1827 control subjects, 53 (19%) and 230 (13%) respectively had received blood transfusions 1 year or more before the interview. Using an age- and sex-stratified analysis the odds ratio (OR) for transfusion was 1.74 (95% CI 1.24-2.44). ORs were also determined for transfusions received in the intervals 1-5, 6-15, 16-25 and > or = 26 years before diagnosis. In the interval 6-15 years, the OR for transfusion was 2.83 (95% CI 1.60-4.99) whereas ORs for transfusions received in other intervals were lower and not significantly elevated. Histological diagnoses (Kiel classification) and results of staging procedures were known for 185 patients. For low-grade NHL of nodal B-cell chronic lymphocytic leukaemia (B-CLL) or immunocytoma type, the OR for transfusions was 4.15 (95% CI 1.92-9.01). For low-grade nodal lymphomas of follicle centre cell type and high-grade nodal lymphomas, no relation to transfusions could be demonstrated. For high-grade extranodal lymphoma as sole manifestation, OR for transfusions was 3.27 (95% CI 1.30-8.24). It is concluded that blood transfusion may be a risk factor for NHLs especially those of B-CLL or immunocytoma type and for high-grade extranodal lymphoma.
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| 14. |
- Harvey, P, et al.
(författare)
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The electric field instrument on the Polar satellite
- 1995
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Ingår i: Space Science Reviews. - 0038-6308 .- 1572-9672. ; 71, s. 583-596
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Tidskriftsartikel (refereegranskat)abstract
- The Polar satellite carries a system of four wire booms in the spacecraft spin plane and two rigid booms along the spin axis. Each of the booms has a spherical sensor at its tip along with nearby guard and stub surfaces whose potentials relative to that of their sphere are controlled by associated electronics. The potential differences between opposite sphere pairs are measured to yield the three components of the DC to >1 MHz electric field. Spheres can also be operated in a mode in which their collected current is measured to give information on the plasma density and its fluctuations. The scientific studies to be performed by this experiment as well as the mechanical and electrical properties of the detector system are described.
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| 15. |
- Jerkeman, Mats, et al.
(författare)
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CHOP versus MACOP-B in aggressive lymphoma--a Nordic Lymphoma Group randomised trial
- 1999
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Ingår i: Annals of Oncology. - 1569-8041. ; 10:9, s. 1079-1086
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: The long-term survival of patients with advanced stage aggressive lymphoma has not improved significantly during the last twenty years. In a randomised trial, the efficacy of MACOP-B, a six-drug weekly chemotherapy regimen, was compared to CHOP, the current standard regimen, in terms of overall and failure-free survival, toxicity and health related quality of life. PATIENTS AND METHODS: Four hundred five patients with aggressive lymphoma, stage II-IV, age 18-67, were randomised to receive either 12 weeks of MACOP-B or 8 courses of CHOP over 24 weeks. Special emphasis was put in the definition of Ann Arbor stage in extranodal disease. A subset of 95 patients also entered a quality of life study, based on the EORTC QLQ-C30. RESULTS: Thirty-one patients were ineligible. Among the remaining 374 patients, the median age was 52 years. According to the age-adjusted International Prognostic Index, 37% were 'high-intermediate' or 'high-risk' patients. No difference could be demonstrated, either in overall survival (60% at five years in the MACOP-B group and 59% in the CHOP group) or in failure-free survival (47% at five years with MACOP-B and 44% with CHOP). In terms of quality of life, physical function and global quality of life were more impaired in patients receiving MACOP-B, who also exhibited more non-haematological toxicity. CONCLUSION: No superiority of MACOP-B compared to CHOP could be demonstrated. CHOP remains the treatment of choice in low-risk patients. At present, intensified or experimental treatment should be reserved for high-risk disease.
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| 18. |
- Malomed, B. A., et al.
(författare)
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Spatiotemporal solitons in multidimensional optical media with a quadratic nonlinearity
- 1997
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Ingår i: Physical Review E. Statistical, Nonlinear, and Soft Matter Physics. - 1063-651X .- 1095-3787. ; 56:4, s. 4725-4735
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Tidskriftsartikel (refereegranskat)abstract
- We consider solutions to the second-harmonic generation equations in two- and three-dimensional dispersive media in the form of solitons localized in space and time. As is known, collapse does not take place in these models, which is why the solitons may be stable. The general solution is obtained in an approximate analytical form by means of a variational approach, which also allows the stability of the solutions to be predicted. Then, we directly simulate the two-dimensional case, taking the initial configuration as suggested by the variational approximation. We thus demonstrate that spatiotemporal solitons indeed exist and are stable. Furthermore, they are not, in the general case, equivalent to the previously known cylindrical spatial solitons. Direct simulations generate solitons with some internal oscillations. However, these oscillations neither grow nor do they exhibit any significant radiative damping. Numerical solutions of the stationary version of the equations produce the same solitons in their unperturbed form, i.e., without internal oscillations. Strictly stable solitons exist only if the system has anomalous dispersion at both the fundamental harmonic and second harmonic (SH), including the case of zero dispersion at SH. Quasistationary solitons, decaying extremely slowly into radiation, are found in the presence of weak normal dispersion at the second-harmonic frequency
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| 23. |
- Sumitran-Holgersson, S, et al.
(författare)
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Porcine embryonic brain cell cytotoxicity mediated by human natural killer cells
- 1999
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Ingår i: Cell Transplantation. - : SAGE Publications. - 0963-6897 .- 1555-3892. ; 8:6, s. 10-601
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Tidskriftsartikel (refereegranskat)abstract
- Intracerebral transplantation of porcine embryonic dopamine-producing neurons has been suggested as a method to treat patients with Parkinson's disease. Even though the brain is an immunologically privileged site, neuronal xenografts are usually rejected within a few weeks. T cells are important for this process, but the exact cellular events leading to rejection are poorly characterized. Brain cells from ventral mesencephalon of 26-27-day-old pig embryos were used as target cells in flow cytometry-assessed cytotoxicity assays using non- and IL-2-activated CD3- CD16+ CD56+ human natural killer (NK) cells as effector cells. The ability of human NK cells to kill pig embryonic brain cells by antibody-dependent cellular cytotoxicity (ADCC) in the presence of nondepleted and anti-Gal alpha1,3Gal antibody-depleted human blood group AB serum (AB serum) was evaluated using the same assay. Both nondepleted and anti-Gal alpha1,3Gal antibody-depleted AB serum could mediate ADCC of pig embryonic VM cells when human NK cells were used as effector cells. Nonactivated NK cells did not show any direct cytotoxic effect on freshly isolated VM cells, whereas IL-2-activated NK cells killed approximately 50% of the VM cells at an effector-to-target ratio of 50:1 in a 4-h cytotoxicity assay. Activation of VM cells by TNF-alpha did not change their sensitivity to human NK cell cytotoxicity. Human NK cells may thus contribute to a cellular rejection of pig neuronal xenografts by ADCC, or following IL-2 activation, by a direct cytotoxic effect.
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| 24. |
- Westerdahl, J, et al.
(författare)
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Reproducibility of a self-administered questionnaire for assessment of melanoma risk
- 1996
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Ingår i: International Journal of Epidemiology. - 0300-5771. ; 25:2, s. 245-251
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: The reproducibility of a self-administered questionnaire on different epidemiological variables was examined in a random sample of a cohort of healthy women from the South Swedish Health Care Region. An identical questionnaire has previously been used for assessment of melanoma risk, in a population-based, matched, case-control study from the same region.METHODS: Repeat questionnaires were completed on two occasions, 1-3 years apart, by 670 randomly selected subjects. In addition, exposure data from a case-control study were used to estimate the effect of misclassification.RESULTS: Overall, there was a fair to good consistency between the answers on the two occasions for the various epidemiological variables. Exposure variables identified as risk factors for melanoma development were reasonably reproducible. The estimated proportion of agreement, A, ranged from 0.74 to 0.92, the average correct classification rate (assuming common sensitivity and specificity), pi, was > or = 0.85 and the kappa coefficient, kappa, ranged between 0.52 and 0.83. However, the question on number of raised naevi on the arm was an exception since it had a lower test-retest reliability (A = 0.62, pi = 0.77, kappa = 0.40). When using data from the case-control study, the effect of the estimated random misclassification was found to only slightly bias odds ratios toward one.CONCLUSION: Our questionnaire, used for assessment for melanoma risk, provided information with fair to good test-retest reliability, and corrected odds ratios were found to be only slightly higher than observed odds ratios.
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