| 1. |
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| 2. |
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| 3. |
- Andersson, Karl-Magnus, et al.
(författare)
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Interspecific and host-related gene expression patterns in nematode-trapping fungi.
- 2014
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Ingår i: BMC Genomics. - : Springer Science and Business Media LLC. - 1471-2164. ; 15:1
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Tidskriftsartikel (refereegranskat)abstract
- Nematode-trapping fungi are soil-living fungi that capture and kill nematodes using special hyphal structures called traps. They display a large diversity of trapping mechanisms and differ in their host preferences. To provide insights into the genetic basis for this variation, we compared the transcriptome expressed by three species of nematode-trapping fungi (Arthrobotrys oligospora, Monacrosporium cionopagum and Arthrobotrys dactyloides, which use adhesive nets, adhesive branches or constricting rings, respectively, to trap nematodes) during infection of two different plant-pathogenic nematode hosts (the root knot nematode Meloidogyne hapla and the sugar beet cyst nematode Heterodera schachtii).
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| 4. |
- Andersson, Karl-Magnus, et al.
(författare)
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Proteome of the nematode-trapping cells of the fungus Monacrosporium haptotylum.
- 2013
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Ingår i: Applied and Environmental Microbiology. - 0099-2240. ; 79:16, s. 4993-5004
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Tidskriftsartikel (refereegranskat)abstract
- Many nematophagous fungi use morphological structures called traps to capture nematodes by adhesion or mechanically. To better understand the cellular functions of adhesive traps, the trap cell proteome of the fungus Monacrosporium haptotylum was characterized. The trap of M. haptotylum consists of a unicellular structure called knob that develops at the apex of a hyphae. Proteins extracted from knobs and mycelia were analyzed using SDS-PAGE and LC-MS/MS. The peptide sequences were matched against predicted gene models from the recently sequenced M. haptotylum genome. In total, 336 proteins were identified, with 54 being expressed at significantly higher levels in the knobs than in the mycelia. The upregulated knob proteins included peptidases, small secreted proteins with unknown function and putative cell surface adhesins containing carbohydrate-binding domains including the WSC domain. Phylogenetic analysis showed that all upregulated WSC domain proteins belonged to a large, expanded cluster of paralogs in M. haptotylum. Several peptidases and homologs to experimentally verified proteins in other pathogenic fungi were also upregulated in the knob proteome. Complementary profiling of gene expression at the transcriptome level showed poor correlation between the upregulation of knob proteins and their corresponding transcripts. We propose that the traps of M. haptotylum contain many of the proteins needed in the early stages of infection, and that the trap cells can tightly control the translation and degradation of these proteins to minimize the cost of protein synthesis.
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| 5. |
- Andersson, Pontus, 1971, et al.
(författare)
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Nearly complete isobar suppression by photodetachment
- 2010
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Ingår i: Journal of Applied Physics. - : AIP Publishing. - 1089-7550 .- 0021-8979. ; 107:2
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Tidskriftsartikel (refereegranskat)abstract
- The efficiency of selective suppression of negative ions by photodetachment in a gas-filled radio frequency quadrupole ion cooler was investigated with a new detection method. A neodymium doped yttrium aluminum garnet laser beam at 1064 nm was used to remove Co− ions in the radio frequency quadrupole cooler and the remaining ions were then probed by photodetachment and neutral particle detection. More than 99.99% suppression of the Co− ions was observed. Under identical conditions, only 20% of a Ni− beam was suppressed. The results demonstrate that this isobar suppression technique can lead to nearly complete elimination of certain isobaric contaminants in negative ion beams, opening up new experimental possibilities in nuclear and atomic research and accelerator mass spectrometry.
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| 6. |
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| 7. |
- Bergsjö, Dag Henrik, 1980, et al.
(författare)
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Industrial Scale Production of Customized Ceramic Prostheses
- 2014
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Ingår i: Advanced Ceramics for Dentistry, 1st Edition. ; , s. 416-
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Today, there are many solutions for dental rehabilitation. A damaged tooth can be replaced with a dental crown, and a toothless patient can be rehabilitated with implants and a corresponding bridge set-up. Traditionally, a dental crown is manufactured by veneering porcelain to a metal surface that is obtained through the use of casting principles. Implant rehabilitations used to rely on a high degree of handcraft by the dentist, where freehand drilling into the jaw- bone was supported by X-ray pictures and was done before implant insertion. Crown and implant rehabilitations can be provided at a much higher degree of industrialization by means of mass customization. The most common dental rehabilitations are crown restorations for single teeth, while full arch implant rehabilitations are the most comprehensive treatments. Trends in industry lean toward a higher degree of automation in production and manufacturing where key characteristics of a well-functioning ceramic prosthesis are cost reduction, patient satisfaction, and quality in both function and perception.
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| 8. |
- Brinkfeldt, Klas, et al.
(författare)
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High temperature packaging for SiC power transistors
- 2012
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Ingår i: Proceedings - 2012 45th International Symposium on Microelectronics, IMAPS 2012. ; , s. 1124-1130
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Konferensbidrag (refereegranskat)abstract
- Power transistors based on silicon carbide (SiC) are now commercially available. They have a higher efficiency and higher voltage blocking capabilities than conventional silicon devices. The wide-band gap and chemical inertness of SiC makes it suitable to high temperature operation. However, there is a need for new packaging for power transistors that can operate in higher temperatures. We have developed a package based on ceramics and silver for high temperature operation of SiC power transistors. Three types of SiC devices from different manufacturers are packaged and tested in room temperature. Though the devices were still functional after the packaging process, their performance seem to have degraded. This could be a result of the high temperature packaging process and the measurement setup. FEM simulations are also performed to investigate the thermo-mechanical behavior of the package. The target operating temperature of the package is 400°C. Modeling show stress concentrations at the corners of the device chip and suggests that this stress is decreased if the substrate metallization is changed from copper to silver.
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| 9. |
- Brinkfeldt, Klas, et al.
(författare)
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Modeling of SiC power modules with double sided cooling
- 2014
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Ingår i: 2014 15th International Conference on Thermal, Mechanical and Multi-Physics Simulation and Experiments in Microelectronics and Microsystems, EuroSimE 2014. - : IEEE Computer Society. - 9781479947904
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Konferensbidrag (refereegranskat)abstract
- Silicon Carbide (SiC) based transistor devices have demonstrated higher efficiency switching operation compared to silicon-based, state-of-the-art solutions due to the superior electrical and thermal properties of the SiC material. The improved current density and thermal conductivity allows SiC-based power modules to be smaller than their silicon counterparts for comparable current densities. The active chip area can be reduced further by effectively cooling the devices. In this work, a new power module including SiC bipolar junction transistors (BJT) and diodes and integrated double sided cooling will be introduced. The target application of these modules is a new drive-train system for commercial electric vehicles.
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| 10. |
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| 11. |
- Brinkfeldt, Klas, et al.
(författare)
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Thermo-mechanical simulations and measurements on high temperature interconnections
- 2011
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Ingår i: 12th Int. Conf. on Thermal, Mechanical and Multi-Physics Simulation and Experiments in Microelectronics and Microsystems, EuroSimE 2011. - 9781457701078
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Konferensbidrag (refereegranskat)abstract
- In order to place sensors or electronics in very high temperature environments, new materials and methods for interconnection are required. A comparative study between different electrical interconnection methods for very high operation temperatures (500 °C - 800 °C) is presented. Thermo-mechanical simulations and characterization of samples of the interconnection types during high temperature exposure are presented. The results of the thermo-mechanical simulations showed that stresses are low in a connection system based on liquid interconnection. This system, however, proved to be difficult to realize due to problems with oxides and sealing of the metallic liquid. Modeling of an interconnection based purely on mechanical pressure without any solder or metallic bond showed high stress. This was also confirmed during high temperature exposure where the connection failed. High stress was also predicted for an interconnection based on nano-Ag paste. The high temperature tests, however, showed promising results at 800 °C for over 100 hours. © 2011 IEEE.
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| 12. |
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| 13. |
- Diehl, C., et al.
(författare)
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Ion optical design of a collinear laser-negative ion beam apparatus
- 2011
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Ingår i: Review of Scientific Instruments. - : AIP Publishing. - 0034-6748 .- 1089-7623. ; 82:5
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Tidskriftsartikel (refereegranskat)abstract
- An apparatus for photodetachment studies on atomic and molecular negative ions of medium up to heavy mass (M ≃ 500) has been designed and constructed. Laser and ion beams are merged in the apparatus in a collinear geometry and atoms, neutral molecules and negative ions are detected in the forward direction. The ion optical design and the components used to optimize the mass resolution and the transmission through the extended field-free interaction region are described. A 90° sector field magnet with 50 cm bending radius in combination with two slits is used for mass dispersion providing a resolution of M/ΔM≅800 for molecular ions and M/ΔM≅400 for atomic ions. The difference in mass resolution for atomic and molecular ions is attributed to different energy distributions of the sputtered ions. With 1 mm slits, transmission from the source through the interaction region to the final ion detector was determined to be about 0.14%.
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| 14. |
- Edwards, Michael, et al.
(författare)
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The shear strength of nano-Ag solders and the use of Ag interconnects in the design and manufacture of SiGe-based thermo-electric modules
- 2014
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Ingår i: 2014 15th International Conference on Thermal, Mechanical and Multi-Physics Simulation and Experiments in Microelectronics and Microsystems, EuroSimE 2014. - : IEEE Computer Society. - 9781479947904
-
Konferensbidrag (refereegranskat)abstract
- Thermo-electric modules can be used to convert heat into electricity by utilizing the Seeback effect. It is now possible to buy BiTe thermo-electric modules that can operate up to temperatures of around 300°C. However, many applications, such as the harvesting of exhaust gas from large vehicles or gas turbine heat, may occur at higher temperatures Therefore, new materials and manufacturing processes need to be developed to produce packaged TEM that can operate at a maximum operating temperature of 650°C. Two critical areas in the manufacture of a SiGe TEM are the choice and strength of materials used to both solder the TE material to the rest of the module and the metal used for the interconnects. The interconnection material needs to be sufficiently strong to withstand large temperature fluctuations while maintaining a low contact resistance, as well as being compatible with the nano-Ag solder. Shear force tests of the sintered thermo electrical leg material showed that the joints are brittle when sintered to W metallized AlN substrates are used and ductile fracture behavior when sintered to Cu metallized AlN substrates using the NanoTach K nano silver paste. Almost all of the joints were found to be brittle when using the NachTach X nano silver paste. Shear testing of the solder joints showed that the X paste joints were variable in strength and stiffness, having a typical Young's modulus between 10 and 100 MPa at room temperature. The K paste joints were stiffer, but had a similar strength as compared to the X paste joints.
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| 15. |
- Ellingsen, Dag G, et al.
(författare)
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Pneumoproteins and inflammatory biomarkers in asphalt pavers.
- 2010
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Ingår i: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. - 1366-5804. ; 15:6, s. 498-507
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Tidskriftsartikel (refereegranskat)abstract
- Pneumoproteins, biomarkers of systemic inflammation and endothelial activation were studied across a season in 72 asphalt pavers, 32 asphalt plant operators and 19 asphalt engineers. Smokers had lower concentrations of Clara cell protein (CC-16) and surfactant protein A, but higher concentrations of surfactant protein D, interleukin 6, C-reactive protein, fibrinogen and intercellular adhesion molecule (ICAM)-1 than non-smokers. Smokers reporting wheezing had lower mean CC-16 concentration than smokers not reporting wheezing (5.7 vs 8.6 microg l(-1); p = 0.05). Cholesterol, P-selectin and ICAM-1 were lower in pavers and operators at the end compared with the start of the season. This may be related to increased physical activity during the season.
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| 16. |
- Fant, Federica, et al.
(författare)
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Thoracic epidural analgesia or patient-controlled local analgesia for radical retropubic prostatectomy: a randomized, double-blind study
- 2011
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Ingår i: British Journal of Anaesthesia. - : Oxford University Press (OUP). - 0007-0912 .- 1471-6771. ; 107:5, s. 782-789
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Tidskriftsartikel (refereegranskat)abstract
- Background. Postoperative pain after radical retropubic prostatectomy is moderate to severe. The primary aim of this study was to assess whether intra-abdominal local anaesthetics provide similar analgesia compared with thoracic epidural analgesia (TEA). less thanbrgreater than less thanbrgreater thanMethods. Fifty patients, ASA I-II, participated in this prospective, double-blinded study. All patients had TEA. After operation, they were randomized into two groups of 25 patients: Group PCLA (patient-controlled local analgesia): self-administration of 10 ml of ropivacaine 2 mg ml(-1) via the intra-abdominal catheter for 48 h. Group TEA: infusion of 10 ml h(-1) of ropivacaine 1 mg ml(-1), fentanyl 2 mg ml(-1), and epinephrine 2 mg ml 21 epidurally for 48 h. The primary endpoint was pain on coughing at 4 h after operation. Rescue medication was morphine i.v. as required. less thanbrgreater than less thanbrgreater thanResults. Pain on coughing at 4, 24, and 48 h was significantly lower in Group TEA [0 (0-10)] compared with Group PCLA [4 (0-10)] (Pandlt;0.05). Significantly lower pain intensity was also found in Group TEA compared with Group PCLA at the incision site, deep pain, and pain on coughing at 4 and 24 h (Pandlt;0.05). Morphine consumption was significantly greater in Group PCLA [12 (0-46)] compared with Group TEA [0 (0-20)] at 0-48 h after operation [median (range)] (P=0.015). Maximum expiratory pressure was higher in Group TEA compared with Group PCLA at 24 h (Pandlt;0.01). less thanbrgreater than less thanbrgreater thanConclusions. TEA provides superior postoperative pain relief with better preservation of expiratory muscle strength compared with PCLA.
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| 17. |
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| 18. |
- Hearn, Jeff, 1947-, et al.
(författare)
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Hegemonic masculinity and beyond : 40 years of research in Sweden
- 2012
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Ingår i: Men and Masculinities. - Thousand Oaks, CA : Sage Publications. - 1097-184X .- 1552-6828. ; 15:1, s. 31-55
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Tidskriftsartikel (refereegranskat)abstract
- This article discusses the status of the concept of hegemonic masculinity in research on men and boys in Sweden, and how it has been used and developed. Sweden has a relatively long history of public debate, research, and policy intervention in gender issues and gender equality. This has meant, in sheer quantitative terms, a relatively sizeable corpus of work on men, masculinities, and gender relations. There is also a rather wide diversity of approaches, theoretically and empirically, to the analysis of men and masculinities. The Swedish national context and gender equality project is outlined. This is followed by discussion of three broad phases in studies on men and masculinities in Sweden: the 1960s and 1970s before the formulation of the concept of hegemonic masculinity; the 1980s and 1990s when the concept was important for a generation of researchers developing studies in more depth; and the 2000s with a younger generation committed to a variety of feminist and gender critiques other than those associated with hegemonic masculinity. The following sections focus specifically on how the concept of hegemonic masculinity has been used, adapted, and indeed not used, in particular areas of study: boys and young men in family and education; violence; and health. The article concludes with review of how hegemonic masculinity has been used in Swedish contexts, as: gender stereotype, often out of the context of legitimation of patriarchal relations; "Other" than dominant, white middle-class "Swedish," equated with outmoded, nonmodern, working-class, failing boy, or minority ethnic masculinities; a new masculinity concept and practice, incorporating some degree of gender equality; and reconceptualized and problematized as a modern, heteronormative, and subject-centered concept.
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| 19. |
- Kroupa, Ales, et al.
(författare)
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Current problems and possible solutions in high-temperature lead-free soldering
- 2012
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Ingår i: Journal of materials engineering and performance (Print). - : Springer Science and Business Media LLC. - 1059-9495 .- 1544-1024. ; 21:5, s. 629-637
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Tidskriftsartikel (refereegranskat)abstract
- The substitution of lead in the electronics industry is one of the key issues in the current drive towards ecological manufacturing. Legislation has already banned the use of lead in solders for mainstream applications (T M≈220 °C), but the use of lead in the solders for high-temperature applications (>85% lead, T M≈250-350 °C) is still exempt in RoHS2. The search for proper substitutes has been ongoing among solder manufacturers only for a decade without finding a viable low cost alternative and is the subject of intensive research. This article tries to map the current situation in the field of high-temperature lead-free soldering, presenting a short review of current legislation, requirements for substitute alloys, and finally it describes some existing solutions both in the field of promising new materials and new technologies. Currently, there is no drop-in replacement for lead-containing solders and therefore both the new materials and the new technologies may be viable solutions for production of reliable lead-free joints for high-temperature applications.
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| 20. |
- Leopold, Tobias, et al.
(författare)
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Feasibility of photodetachment isobar suppression of WF5- with respect to HfF5
- 2014
-
Ingår i: International Journal of Mass Spectrometry. - : Elsevier BV. - 1387-3806 .- 1873-2798. ; 359, s. 12-18
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Tidskriftsartikel (refereegranskat)abstract
- The feasibility of using laser photodetachment as a means for isobar suppression in accelerator mass spectrometry has been investigated for the special case of HfF5-/WF5-. A method for absolute photodetachrnent cross section measurements was applied and the cross sections of tungsten pentafluoride and hafnium pentafluoride negative ions were measured. The measurements indicate that the photodetachment cross section for WF5- is at least 100 times larger than for HfF5- at the wavelength of the fourth harmonic of the Nd:YAG laser at 266 nm. The absolute cross section for WF5- at this photon energy was found to be (2.8 +/- 0.3) x 10(-18) cm(2), while an upper limit of 2 x 10(-2) cm(2) was obtained for the HfF5- cross section. The measured cross sections indicate that an optical filtering scheme for isobar suppression in accelerator mass spectrometry for the case of Hf-182 should be feasible. (C) 2013 Elsevier B.V. All rights reserved.
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| 21. |
- Lindahl, Anton, 1982, et al.
(författare)
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The electron affinity of tungsten
- 2010
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Ingår i: The European Physical Journal D - Atomic, Molecular, Optical and Plasma Physics. - : Springer Science and Business Media LLC. - 1434-6060 .- 1434-6079. ; 60:2, s. 219-222
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Tidskriftsartikel (refereegranskat)abstract
- The electron affinity of tungsten has been measured using laser photodetachment threshold spectroscopy in a collinear geometry. The electron affinity was determined to 6583.6(6) cm-1 by observing the onset of the process when W- ions in the 6S5/2 ground state are photodetached producing neutral W atoms in the 5D0 ground state. The measured value is in agreement with previous measurements and improves the accuracy by almost two orders of magnitude. Further, a photodetachment signal below the ground state photodetachment threshold was found, which indicates the existence of a bound excited state in W-.
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| 22. |
- Liu, Y., et al.
(författare)
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Beam purification by photodetachment (invited)
- 2012
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Ingår i: Review of Scientific Instruments. - : AIP Publishing. - 0034-6748 .- 1089-7623. ; 83:2
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Tidskriftsartikel (refereegranskat)abstract
- Ion beam purity is of crucial importance to many basic and applied studies in nuclear science. Selective photodetachment has been proposed to suppress unwanted species in negative ion beams while preserving the intensity of the species of interest. A highly efficient technique based on photodetachment in a gas-filled radio frequency quadrupole ion cooler has been demonstrated. In off-line experiments with stable ions, up to 104 times suppression of the isobar contaminants in a number of interesting radioactive negative ion beams has been demonstrated. For selected species, this technique promises new experimental possibilities in studies on exotic nuclei, accelerator mass spectrometry, and fundamental properties of negative atomic and molecular ions.
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| 23. |
- Malmodin, Jens, et al.
(författare)
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Life Cycle Assessment of ICT : Carbon Footprint and Operational Electricity Use from the Operator, National, and Subscriber Perspective in Sweden
- 2014
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Ingår i: Journal of Industrial Ecology. - : Wiley. - 1088-1980 .- 1530-9290. ; 18:6, s. 829-845
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Tidskriftsartikel (refereegranskat)abstract
- The use of information and communication technology (ICT) is growing throughout society, and new products and solutions are developed at an increasing rate. To enable environmental assessment of specific ICT products and other products that rely on ICT in some way, a more complete, detailed, and up-to-date study based on real measurements is needed. To date, similar studies have not been readily available or fully comprehensive. This study assessed the overall operational electricity use and life-cycle-based carbon footprint (CF) relating to ICT in Sweden, including activities not commonly addressed previously, such as shared data transport networks and data centers and manufacturing of network infrastructure. Specific, detailed inventory data are presented and used for assessment of the Internet Protocol core network, data transmission, operator activities, and access network. These specific data, in combination with secondary, more generic data for end-user equipment, allow a comprehensive overall assessment. The majority of the ICT network CF is the result of end-user equipment, mainly personal computers, followed by third-party enterprise networks and data centers and then access networks. The parts closest to the user proved to be clearly responsible for the majority of the impact. The results are presented for Swedish ICT networks and for ICT networks in general based on a global average electricity mix.
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| 24. |
- Martschini, M., et al.
(författare)
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AMS of Cl-36 with the VERA 3 MV tandem accelerator
- 2013
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Ingår i: Nuclear Instruments & Methods in Physics Research Section B-Beam Interactions with Materials and Atoms. - : Elsevier BV. - 0168-583X. ; 294, s. 115-120
-
Tidskriftsartikel (refereegranskat)abstract
- Recent progress with compact ionization chambers has opened new possibilities for isobar Refraining from the additional use of degrader foils has the benefit of high transmission to the detector Precision and accuracy have been thoroughly assessed over the last two years. Since drifts in the Recently we also explored novel techniques for additional sulfur suppression already in the ion source.
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| 25. |
- Martschini, Martin, et al.
(författare)
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Light induced suppression of sulfur in a cesium sputter ion source
- 2012
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Ingår i: International Journal of Mass Spectrometry. - : Elsevier BV. - 1387-3806. ; 315, s. 55-59
-
Tidskriftsartikel (refereegranskat)abstract
- New techniques for suppression of atomic isobars in negative ion beams are of great interest for accelerator mass spectrometry (AMS). Especially small and medium-sized facilities can significantly extend their measurement capabilities to new interesting isotopes with a technique independent of terminal voltage. In a new approach, the effect of continuous wave laser light directed towards the cathode surface in a cesium sputter ion source of the Middleton type was studied. The laser light induced a significant change in oxygen, sulfur and chlorine negative ion production from a AgCl target. Approximately 100 mW of laser light reduced the sulfur to chlorine ratio by one order of magnitude. The effect was found to depend on laser power and ion source parameters but not on the laser wavelength. The time constant of the effect varied from a few seconds up to several minutes. Experiments were first performed at the ion beam facility GUNILLA at University of Gothenburg with macroscopic amounts of sulfur. The results were then reproduced at the VERA AMS facility with chemically cleaned AgCl targets containing ∼1 ppm sulfur. The physical explanation behind the effect is still unclear. Nevertheless, the technique has been successfully applied during a regular AMS measurement of 36Cl.
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| 26. |
- Meerupati, Tejashwari, et al.
(författare)
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Genomic Mechanisms Accounting for the Adaptation to Parasitism in Nematode-Trapping Fungi
- 2013
-
Ingår i: PLoS Genetics. - : Public Library of Science (PLoS). - 1553-7404. ; 9:11
-
Tidskriftsartikel (refereegranskat)abstract
- Orbiliomycetes is one of the earliest diverging branches of the filamentous ascomycetes. The class contains nematode-trapping fungi that form unique infection structures, called traps, to capture and kill free-living nematodes. The traps have evolved differently along several lineages and include adhesive traps (knobs, nets or branches) and constricting rings. We show, by genome sequencing of the knob-forming species Monacrosporium haptotylum and comparison with the net-forming species Arthrobotrys oligospora, that two genomic mechanisms are likely to have been important for the adaptation to parasitism in these fungi. Firstly, the expansion of protein domain families and the large number of species-specific genes indicated that gene duplication followed by functional diversification had a major role in the evolution of the nematode-trapping fungi. Gene expression indicated that many of these genes are important for pathogenicity. Secondly, gene expression of orthologs between the two fungi during infection indicated that differential regulation was an important mechanism for the evolution of parasitism in nematode-trapping fungi. Many of the highly expressed and highly upregulated M. haptotylum transcripts during the early stages of nematode infection were species-specific and encoded small secreted proteins (SSPs) that were affected by repeat-induced point mutations (RIP). An active RIP mechanism was revealed by lack of repeats, dinucleotide bias in repeats and genes, low proportion of recent gene duplicates, and reduction of recent gene family expansions. The high expression and rapid divergence of SSPs indicate a striking similarity in the infection mechanisms of nematode-trapping fungi and plant and insect pathogens from the crown groups of the filamentous ascomycetes (Pezizomycotina). The patterns of gene family expansions in the nematode-trapping fungi were more similar to plant pathogens than to insect and animal pathogens. The observation of RIP activity in the Orbiliomycetes suggested that this mechanism was present early in the evolution of the filamentous ascomycetes.
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| 27. |
- Mishra, Yogeshwar, et al.
(författare)
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A microfluidic device for the study of the orientational dynamics of microrods
- 2012
-
Ingår i: Proc. SPIE 8251, Microfluidics, BioMEMS, and Medical Microsystems X. - : SPIE. ; 8251:825109
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- We describe a microfluidic device for studying the orientational dynamics of microrods. The device enables us to experimentally investigate the tumbling of microrods immersed in the shear flow in a microfluidic channel with a depth of 400 μm and a width of 2.5 mm. The orientational dynamics was recorded using a 20X microscopic objective and a CCD camera. The microrods were produced by shearing microdroplets of photocurable epoxy resin. We show different examples of empirically observed tumbling. On the one hand we find that short stretches of the experimentally determined time series are well described by fits to solutions of Jeffery's approximate equation of motion [Jeffery, Proc. R. Soc. London. 102 (1922), 161-179]. On the other hand we find that the empirically observed trajectories drift between different solutions of Jeffery's equation. We discuss possible causes of this orbit drift.
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| 28. |
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| 29. |
- Raudberget, Dag, 1967, et al.
(författare)
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Implementing the principles of Set-based Concurrent
- 2012
-
Ingår i: NordDesign 2012, August 22 – 24, 2012, Aalborg, Denmark.
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Konferensbidrag (refereegranskat)abstract
- This paper describes a new design approach that implements the three principles of Set-basedConcurrent Engineering by using the concept of Configurable Component modelling. Severalcase studies has proven the efficiency of Configurable Component modelling as well as theSet-based philosophy, and by combining these two research areas, a computer basedmodelling of Configurable Component objects is used to support the Set-based philosophy.The approach is demonstrated by a case study that indicates a promising future of combiningSet-based Concurrent Engineering with Configurable Component modelling for re-designproblems.
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| 30. |
- Raudberget, Dag, 1967, et al.
(författare)
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Implementing the principles of set-based concurrent engineering in configurable component platforms
- 2012
-
Ingår i: NordDesign 2012 - Proceedings of the 9th NordDesign Conference. - Aalborg : Center for Industrial Production. - 9788791831515
-
Konferensbidrag (refereegranskat)abstract
- This paper describes a new design approach that implements the three principles of Set-based Concurrent Engineering by using the concept of Configurable Component modelling. Several case studies has proven the efficiency of Configurable Component modelling as well as the Set-based philosophy, and by combining these two research areas, a computer based modelling of Configurable Component objects is used to support the Set-based philosophy. The approach is demonstrated by a case study that indicates a promising future of combining Set-based Concurrent Engineering with Configurable Component modelling for re-design problems.
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| 31. |
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| 32. |
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| 33. |
- Sánchez-Soriano, Miguel Angel, et al.
(författare)
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Mutiphysics study of RF/microwave planar devices : Effect of the input signal power
- 2014
-
Ingår i: 2014 15th International Conference on Thermal, Mechanical and Multi-Physics Simulation and Experiments in Microelectronics and Microsystems, EuroSimE 2014. - : IEEE Computer Society. - 9781479947904
-
Konferensbidrag (refereegranskat)abstract
- In this paper, the effects of the input signal power on microwave planar devices are studied in detail. In this context, a complete multiphysics study is performed, involving the electro-thermo-mechanical coupling in microwave components. For this study, a multiphysics simulator is used. As shown, for moderate input powers, the device transfer function can be altered, mainly in terms of an increase of losses and a frequency shift. Additionally, hot spots are to be appeared, whose location is related to the electromagnetic field distribution of the passive device under test. Guidelines are also provided to estimate the average power handling capability (APHC) of planar components. As an example, the multiphysics analysis of a microstrip coupled-line filter centered at 42 GHz is tackled taken into account different thermal and mechanical boundary conditions.
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| 34. |
- Ström, Mikael, et al.
(författare)
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UML modelling concepts of HAZOP to enhance the ability to identify emerging risks
- 2013
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Ingår i: Journal of Risk Research. - : Informa UK Limited. - 1366-9877 .- 1466-4461. ; 16:3-4, s. 421-432
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Tidskriftsartikel (refereegranskat)abstract
- Unified Modelling Language (UML) has a graphical notation for 13 different types of diagrams and can be used as a general modelling tool. Well-known examples of diagram types are class diagrams for modelling classes that can be instanced into objects, state machine diagrams for modelling states in systems and activity diagrams for modelling process flows. A literature survey shows that UML has been used to model concepts and methodologies of risk assessment and risk management. One example is the Coras Framework. The international standard CEI IEC 61882 Hazard and operability (HAZOP) studies describes concepts for investigating and detecting possible hazards in systems. In CEI IEC 6882, guide words like More and Less are applied to system parameters to invoke deviations in the system and assess possible hazards due to the deviation from the design intent. In this paper, we have used UML to model concepts of CEI IEC 61882 Hazards and operability studies. Diagrams of UML were used to show dependencies and relations between parts of the target system and concepts of CEI IEC 61882. Extensions of UML are suggested to better capture and display the concepts of CEI IEC 61882, the results of a HAZOP study and emerging risk. These extensions are referred to as UML for emerging risks (UML-ER).
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| 35. |
- Wedelin, Dag, 1964, et al.
(författare)
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Teaching and learning mathematical modelling and problem solving: A case study
- 2013
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Ingår i: 1st International Conference of the Portuguese-Society-for-Engineering-Education (CISPEE), November 2013, Porto, Portugal. - 9781479912193
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Konferensbidrag (refereegranskat)abstract
- Engineering students often fail to connect and apply what they have learnt in introductory mathematics courses to other subjects, sometimes leading to the belief that mathematics is not relevant to them. To bridge this gap between mathematical theory and practice, we have designed a course in mathematical modelling and problem solving at Chalmers University of Technology. The main purpose of the present study is to investigate and better understand what challenges engineering students experience when dealing with mathematical modelling problems and what strategies they use to overcome those challenges. Data was collected through semistructured interviews with six students early in the course and the interviews were based on two problems that the students had solved during the course. The data was analysed using basic strategies for qualitative analysis and led to the identification of two central challenges experienced by the students as well as several strategies for overcoming them. The first challenge is that students are not fully aware of the importance of understanding the problem, and the second is that students get stuck because they do not sufficiently consider alternatives in a non-linear solution process. While these issues have little to do with mathematical modelling as such, the modelling problems given clearly reveal these shortcomings, which we see as lacking problem solving skills. Our findings confirm the importance of teaching mathematical modelling and problem solving, and in a more general setting we see cognitive apprenticeship as a promising framework for teaching and learning in engineering education.
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| 36. |
- Öhrfelt Olsson, Annika, 1973, et al.
(författare)
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Identification of Novel α-Synuclein Isoforms in Human Brain Tissue by using an Online NanoLC-ESI-FTICR-MS Method.
- 2011
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Ingår i: Neurochemical research. - : Springer Science and Business Media LLC. - 1573-6903 .- 0364-3190. ; 36:11, s. 2029-2042
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Tidskriftsartikel (refereegranskat)abstract
- Parkinson's disease (PD) and Dementia with Lewy bodies (DLB) are neurodegenerative diseases that are characterized by intra-neuronal inclusions of Lewy bodies in distinct brain regions. These inclusions consist mainly of aggregated α-synuclein (α-syn) protein. The present study used immunoprecipitation combined with nanoflow liquid chromatography (LC) coupled to high resolution electrospray ionization Fourier transform ion cyclotron resonance tandem mass spectrometry (ESI-FTICR-MS/MS) to determine known and novel isoforms of α-syn in brain tissue homogenates. N-terminally acetylated full-length α-syn (Ac-α-syn(1-140)) and two N-terminally acetylated C-terminally truncated forms of α-syn (Ac-α-syn(1-139) and Ac-α-syn(1-103)) were found. The different forms of α-syn were further studied by Western blotting in brain tissue homogenates from the temporal cortex Brodmann area 36 (BA36) and the dorsolateral prefrontal cortex BA9 derived from controls, patients with DLB and PD with dementia (PDD). Quantification of α-syn in each brain tissue fraction was performed using a novel enzyme-linked immunosorbent assay (ELISA).
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