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- Aronsson, Lars, 1955-, et al.
(author)
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The Tourist : bodies, senses and encounters
- 2001
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In: Turismens och fritidens mångfald. - Karlstad : Karlstad University Studies. - 9189422538 ; , s. 231-250
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Book chapter (peer-reviewed)
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| 12. |
- Aronsson, Lars, 1955-, et al.
(author)
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Tid för resande?
- 2000
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In: Nordisk Samhällsgeografisk Tidskrift, ISSN 0282-4329.
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Journal article (peer-reviewed)
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| 13. |
- Crouch, David, et al.
(author)
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Tourist Encounters
- 2001
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In: Tourist Studies. - 1468-7976 .- 1741-3206. ; 1:3, s. 253-270
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Journal article (peer-reviewed)
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| 14. |
- Nilsson, Ola, 1957, et al.
(author)
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Importance of vesicle proteins in the diagnosis and treatment of neuroendocrine tumors.
- 2004
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In: Annals of the New York Academy of Sciences. - : Wiley. - 0077-8923 .- 1749-6632. ; 1014, s. 280-3
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Journal article (peer-reviewed)abstract
- We have analyzed the expression of synaptic vesicle proteins in human neuroendocrine tumors and the potential use of vesicle proteins in the diagnosis and treatment of neuroendocrine tumors. Biopsies from endocrine and nonendocrine tumors of the gastrointestinal tract, pancreas, and adrenals were examined by immunocytochemistry using antibodies against synaptic vesicle protein 2 (SV2), vesicular monoamine transporter 1 and 2 (VMAT1 and 2), and neuroendocrine secretory protein 55 (NESP55). SV2 was expressed in all endocrine tumors of the gastrointestinal tract and pancreas as well as in gastrointestinal stromal tumors (GISTs). None of the adenocarcinomas expressed SV2. VMAT1 and 2 were expressed in amine-producing tumors of the gastrointestinal tract (ECL cell and EC cell carcinoids) and in a small number of peptide-producing pancreatic endocrine tumors. NESP55 was expressed in neuroblastomas and adrenal pheochromocytomas as well as in a subgroup of pancreatic endocrine tumors. The importance of VMAT1 and 2 for the uptake of 123I-MIBG in tumor cells was demonstrated. It was concluded that neuroendocrine tumors express multiple synaptic vesicle proteins that are useful in the histopathological diagnosis and classification of tumors. Vesicle proteins may prove to be useful for targeting tumor therapy.
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- Vikhoff-Baaz, Barbro, et al.
(author)
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Lateralisation with magnetic resonance spectroscopic imaging in temporal lobe epilepsy: an evaluation of visual and region-of-interest analysis of metabolite concentration images.
- 2001
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In: Neuroradiology. - 0028-3940. ; 43:9, s. 721-7
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Journal article (peer-reviewed)abstract
- We carried out spectroscopic imaging (MRSI) on nine consecutive patients with temporal lobe epilepsy being assessed for epilepsy surgery, and nine neurologically healthy, age-matched volunteers. A volume of interest (VOI) was angled along the temporal horns on axial and sagittal images, and symmetrically over the temporal lobes on coronal images. Images showing the concentrations of N-acetylaspartate (NAA) and of choline-containing compounds plus creatine and phosphocreatine (Cho + Cr) were used for lateralisation. We compared assessment by visual inspection and by signal analysis from regions of interest (ROI) in different positions, where side-to-side differences in NAA/(Cho + Cr) ratio were used for lateralisation. The NAA/ (Cho + Cr) ratio from the different ROI was also compared with that in the brain stem to assess if the latter could be used as an internal reference, e. g., for identification of bilateral changes. The metabolite concentration images were found useful for lateralisation of temporal lobe abnormalities related to epilepsy. Visual analysis can, with high accuracy, be used routinely. ROI analysis is useful for quantifying changes, giving more quantitative information about spatial distribution and the degree of signal loss. There was a large variation in NAA/ (Cho + Cr) values in both patients and volunteers. The brain stem may be used as a reference for identification of bilateral changes.
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