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- Berg, N O, et al.
(författare)
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Bronchocarcinogenic Properties of Welding and Thermal Spraying Fumes Containing Chromium in the Rat
- 1987
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Ingår i: American Journal of Industrial Medicine. - : Wiley. - 0271-3586 .- 1097-0274. ; 11, s. 39-54
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Tidskriftsartikel (refereegranskat)abstract
- The possible bronchocarcinogenic effects of fumes released during the shielded metal arc welding of stainless steel and the thermal spraying of chromium oxide (Cr2O3) have been studied on the rat. The fume particles were shown to contain tri- and hexavalent chromium in soluble and low soluble forms; they were collected and implanted as pellets in the bronchi of groups of 100 rats by the method of Laskin et al. A negative control group of 100 rats was included, as well as positive controls receiving pellets containing benz(a)pyrene. The experiment was continued for 34 months; no differences of biological significance were noted between the growth rates, survival times, and terminal organ weights of the test and negative control groups. At autopsy, the macroscopic and microscopic appearance of the organs in the three groups, including the local reaction to the implanted pellet, were similar. No precancerous changes were observed at the implantation sites; one rat, who received a pellet containing welding fumes, showed squamous cell carcinoma remote from the implantation site and not associated with the bronchus. It had the appearance of a metastasis. All three benz(a)pyrene control rats developed cancer at the implantation site. The occupational health implications of these findings are discussed.
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- Berg, Sören, et al.
(författare)
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Ion assisted selective thin film deposition
- 1986
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Ingår i: Journal of Vacuum Science & Technology. A. Vacuum, Surfaces, and Films. - 0734-2101 .- 1520-8559. ; 4:3, s. 448-
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Tidskriftsartikel (refereegranskat)
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| 8. |
- Berg, Sören, et al.
(författare)
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Process modelling of reactive sputtering
- 1989
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Ingår i: Journal of Vacuum Science & Technology. A. Vacuum, Surfaces, and Films. - 0734-2101 .- 1520-8559. ; 7:3, s. 1225-1229
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Tidskriftsartikel (refereegranskat)
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- Blom, Hans-Olof, et al.
(författare)
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Reactively sputtered titanium boride thin films
- 1989
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Ingår i: Journal of Vacuum Science & Technology. A. Vacuum, Surfaces, and Films. - 0734-2101 .- 1520-8559. ; 7:2, s. 162-165
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Tidskriftsartikel (refereegranskat)
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- Eriksson, M., et al.
(författare)
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Soft-tissue sarcomas and exposure to chemical substances : A case-referent study
- 1981
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Ingår i: British Journal of Industrial Medicine. - : BMJ. - 0007-1072. ; 38:1, s. 27-33
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Tidskriftsartikel (refereegranskat)abstract
- In 1977 several patients were seen with soft-tissue sarcomas and previous exposure to phenoxy acids. This clinical observation resulted in a case-referent (case-control) study being undertaken which showed that exposure to phenoxy acids or chlorophenols, which are chemically related, gave a roughly six-fold increase in the risk for this type of tumor. A further case-referent study of soft-tissue sarcomas has now been performed to confirm these earlier findings and also to obtain further information on the effects of different phenoxy acids. This new investigation gave an increase of the same magnitude in the risk for soft-tissue sarcomas after exposure to phenoxy acids or chlorophenols, but this risk related also to exposure to phenoxy acids free from impurities, such as polychlorinated dibenzodioxins and dibenzofurans.
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