| 1. |
- Kass, G E, et al.
(författare)
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Two separate plasma membrane Ca2+ carriers participate in receptor-mediated Ca2+ influx in rat hepatocytes.
- 1994
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Ingår i: Biochimica et Biophysica Acta. - : Elsevier BV. - 0006-3002 .- 1878-2434. ; 1223:2, s. 226-33
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Tidskriftsartikel (refereegranskat)abstract
- The plasma membrane Ca2+ carrier system involved in receptor-mediated Ca2+ entry was studied. Using the Ca2+ readdition protocol, the rate of cytosolic free Ca2+ concentration ([Ca2+]i) increase in vasopressin-pretreated hepatocytes was significantly higher than in thapsigargin- or 2,5-di(tert-butyl)hydroquinone-pretreated cells. The addition of Mn2+ to unstimulated hepatocytes resulted in a biphasic quench of fura-2 fluorescence. After an initial phase that was fast in rate but of short duration, the rate of fura-2 quench by Mn2+ became much slower and lasted until all the cellular fura-2 was quenched. Pretreatment of the cells with vasopressin only accelerated the rate of the latter phase but not of the initial one. In agonist-stimulated cells, acidification of the extracellular medium or the presence of ruthenium red, econazole or SK&F 96365 decreased the rates of both [Ca2+]i increase and Mn2+ entry upon addition of the respective cation. By contrast, neomycin and N-tosyl-L-phenylalanine chloromethyl ketone markedly decreased the rate of [Ca2+]i increase upon Ca2+ readdition but had no effect on vasopressin-stimulated Mn2+ entry. None of the treatments affected the ability of vasopressin and thapsigargin to mobilize the internal Ca2+ store. It is concluded that in hepatocytes the two pathways of receptor-mediated Ca2+ entry control two distinct yet pharmacologically related cation carriers.
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| 2. |
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| 3. |
- Berggren, Matz S., 1950
(författare)
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Periclimenes nomadophila and Tuleariocaris sarec, two new species of pontoniine shrimps (Crustacea: Decapoda: Pontoniinae), from Inhaca Island, Moçambique
- 1994
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Ingår i: Journal of Crustacean Biology. - 0278-0372. ; 14:4, s. 782-802
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Tidskriftsartikel (refereegranskat)abstract
- Two new species of pontoniine hrimps from Moçambique are described and illustrated. The first species, Periclimenes nomadophila, is the third pontoniine species found to be associated with scyphozoans and the first record of association with a pelagic jellyfish (Rhopilema nomadica). Character differences between closely related species are tabulated and a key to the different species in the Periclimenes obscurus group is presented. The second described species, Tuleariocaris sarec, is the fourth species in its genus. All are associated with sea urchins. Tuleariocaris sarec clings tightly head down, to the spines of its host. A key to the species of the genus Tuleariocarisis presented.
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| 4. |
- Hogenius, S, et al.
(författare)
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Demographical, odontological, and psychological variables in individuals referred for osseointegrated dental implants.
- 1992
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Ingår i: Community dentistry and oral epidemiology. - 0301-5661. ; 20:4, s. 224-8
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Tidskriftsartikel (refereegranskat)abstract
- Edentulism and/or the wearing of a removable denture always requires adaptation, not only on a functional, but also on an emotional, level. Four hundred and seventy-three patients referred for treatment with osseointegrated implants due to problems with removable prostheses entered the study and 315 (66.6%) completed it. The average age was close to 60 yr, and the majority of patients were women. The average time of edentulousness was 14.3 yr. Twelve percent experienced profound negative effects from wearing dentures, this to an extent that it led to overt psychological and social effects. Subjective ratings revealed that functional and/or intra-personal effects were of higher significance than social consequences. The group was found to be more depressed than average as well as having an external health locus of control orientation.
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| 5. |
- Kass, G E, et al.
(författare)
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Receptor-mediated Mn2+ influx in rat hepatocytes : comparison of cells loaded with Fura-2 ester and cells microinjected with Fura-2 salt
- 1994
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Ingår i: Biochemical Journal. - 0264-6021 .- 1470-8728. ; 302, s. 5-9
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Tidskriftsartikel (refereegranskat)abstract
- In single Fura-2 ester-loaded hepatocytes, stimulation by vasopressin, but not emptying of the agonist-sensitive Ca2+ store by 2,5-di-(t-butyl)hydroquinone, resulted in an increase in the rate of Fura-2 fluorescence-quenching by Mn2+. Similarly, in cells microinjected with Fura-2 salt, vasopressin stimulated Mn2+ entry while 2,5-di-(t-butyl)hydroquinone or thapsigargin did not. The pattern of Fura-2 quenching by Mn2+ only correlated with the movement of Mn2+ across the plasma membrane.
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