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- Hallman, David, 1979-, et al.
(författare)
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Contrasting effect of objectively measured physical activity during work and leisure on heart rate variability during sleep
- 2017
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Ingår i: European Journal of Preventive Cardiology. - : Sage Publications. - 2047-4873 .- 2047-4881. ; 24:2S, s. 32-33
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Tidskriftsartikel (refereegranskat)abstract
- Aim: Leisure-time physical activity (LTPA) has a beneficial effect on cardiovascular health and longevity, while occupational physical activity (OPA) is associated with an increased risk of cardiovascular diseases and mortality. The physiological mechanism of this apparently contrasting relationship between LTPA and OPA on cardiovascular health remains unknown. A possible explanation is that OPA and LTPA exert different effects on the autonomic nervous system. Thus, we aimed to investigate whether objectively measured OPA and LTPA are differentially associated with cardiac autonomic regulation in an occupational sample.Methods: Cross-sectional data from the Danish cohort DPHACTO were analysed. The study comprised 514 bluecollar workers who took part in ambulatory monitoring of physical activity and heart rate variability (HRV). Physical activity (i.e. time spent in walking, climbing stairs, running and cycling) was assessed objectively using accelerometers (Actigraph) worn on the thigh, hip and trunk over 4–5 working days. Simultaneously, a heart rate monitor (Actiheart) was used to collect inter-beat intervals from the ECG signal. Heart rate and HRV indices were analysed during nocturnal sleep as markers of cardiac autonomic activity. Multiple regression analysis was used to determinethe main effects of OPA and LTPA and their interaction on heart rate and HRV indices, adjusting for multiple confounders (age, gender, body mass index, smoking and cardiovascular ailments).Results: Time spent in physical activity was on average (SD) 1.4 (0.6) hours/day for OPA and 0.9 (0.4) hours/day for LTPA. OPA showed generally negative associations with nocturnal HRV indices, while positive estimates were observed for LTPA. There was a statistically significant interaction effect between OPA and LTPA on heartrate (P < 0.0001) and HRV indices in time (root mean square of standard deviation, P = 0.004: standard deviation of normal to normal sinus beat, P = 0.019) and frequency domains (high frequency power, P = 0.022; low frequency power, P = 0.033). The favourable effect of LTPA on nocturnal HRV clearly diminished with higher levels of OPA, and high levels of both OPA and LTPA had a detrimental effect. The observed associations persisted after adjustment for possible confounders.Conclusion: Our findings suggest that time spent in OPA and LTPA have interactive effects on nocturnal autonomic regulation. Future longitudinal studies should examine whether autonomic regulation is a mediator for the effect of OPA and LTPA on cardiovascular disease and mortality.
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- Hallman, David M., et al.
(författare)
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Objectively measured physical activity and 12-month trajectories of neck-shoulder pain in workers : a prospective study in DPHACTO
- 2017
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Ingår i: Scandinavian Journal of Public Health. - : SAGE Publications. - 1403-4948 .- 1651-1905. ; 45:3, s. 288-298
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Tidskriftsartikel (refereegranskat)abstract
- Aims: This study aimed to investigate the association between objectively measured physical activity at work and leisure and the intensity (mean level and time course) of neck–shoulder pain (NSP) over 12 months among male and female blue collar workers. Methods: Data were obtained from 625 blue collar workers from the Danish cohort DPHACTO. Physical activity was measured objectively at baseline using accelerometers. The percentage of time spent in physical activity (walking, climbing stairs, running and cycling) was calculated for both work and leisure time. Longitudinal data on the intensity of NSP (numerical rating scale 0–10) were collected using text messages every fourth week over 12 months. Linear mixed models were used to investigate the associations between occupational physical activity (OPA) and leisure time physical activity (LTPA) and the trajectories of the intensity of NSP, adjusted for individual, biomechanical and psychosocial factors, and baseline pain. Results: OPA was not associated with the mean intensity of NSP over 12 months. LTPA was negatively associated with the mean intensity of NSP both among men (B=−0.71, 95% CI −1.31 to −0.11) and women (B=−0.85, 95% CI −1.57 to −0.13). Sex interactions on the 12-month trajectories of NSP showed that higher physical activity was associated with a slower reduction in NSP among men for OPA only (B=0.03, 95% CI 0.01-0.05) and women for LTPA only (B=0.05, 95% CI 0.00-0.09). Conclusions: We found that more time in LTPA was associated with a lower overall intensity of NSP over 12 months among blue collar workers. However, depending on sex and domain, high physical activity had an unfavourable effect on the course of NSP over 12 months.
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- Hallman, David, 1979-, et al.
(författare)
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On the health paradox of occupational and leisure-time physical activity using objective measurements : effects on autonomic imbalance
- 2017
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Ingår i: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 12:5
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Tidskriftsartikel (refereegranskat)abstract
- ObjectiveLeisure-time physical activity (LTPA) has considerable benefits for cardiovascular health and longevity, while occupational physical activity (OPA) is associated with an elevated cardiovascular risk. This “health paradox” may be explained by different effects on the autonomic nervous system from OPA and LTPA. Thus, we aimed to investigate whether objectively measured OPA and LTPA are differentially associated with autonomic regulation among workers.MethodsThe study comprised 514 blue-collar workers from the Danish cohort DPHACTO. Physical activity (i.e. walking, climbing stairs, running and cycling) was assessed objectively using accelerometers worn on the thigh, hip and trunk over multiple working days. During this period, a heart rate monitor was used to sample heart period intervals from the ECG signal. Heart rate and heart rate variability (HRV) indices were analyzed during nocturnal sleep as markers of autonomic regulation. Multiple regression analysis was used to determine the main effects of OPA and LTPA and their interaction on heart rate and HRV, adjusting for multiple confounders.ResultsStatistically significant interaction was found between OPA and LTPA on heart rate (adjusted p<0.0001) and HRV indices in time (rMSSD, adjusted p = 0.004) and frequency-domains (HF, adjusted p = 0.022; LF, adjusted p = 0.033). The beneficial effect of LTPA on nocturnal heart rate and HRV clearly diminished with higher levels of OPA, and high levels of both OPA and LTPA had a detrimental effect.ConclusionWe found contrasting associations for objectively measured OPA and LTPA with heart rate and HRV during sleep. Differential effects of OPA and LTPA on autonomic regulation may contribute to the physical activity health paradox.
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